Volume 15; Issue 22

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Clinical Cancer Research
Volume 15; Issue 22

Clinical Cancer Research

Volume 15; Issue 22

1

Antiphosphatidylserine Antibody Combined with Irradiation Damages Tumor Blood Vessels and Induces Tumor Immunity in a Rat Model of Glioblastoma

He, J., Yin, Y., Luster, T. A., Watkins, L., Thorpe, P. E.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 557 KB

english, 2009

2

Sarcopenia in an Overweight or Obese Patient Is an Adverse Prognostic Factor in Pancreatic Cancer

Tan, B. H.L., Birdsell, L. A., Martin, L., Baracos, V. E., Fearon, K. C.H.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 317 KB

english, 2009

3

A Phase 1 Dose Escalation Study of the Safety and Pharmacokinetics of the Novel Proteasome Inhibitor Carfilzomib (PR-171) in Patients with Hematologic Malignancies

O'Connor, O. A., Stewart, A. K., Vallone, M., Molineaux, C. J., Kunkel, L. A., Gerecitano, J. F., Orlowski, R. Z.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 377 KB

english, 2009

4

Contribution of Degradation Products to the Anticancer Activity of Curcumin

Shen, L., Ji, H.-F.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 104 KB

english, 2009

5

Homozygous Deletion of MTAP Gene as a Poor Prognosticator in Gastrointestinal Stromal Tumors

Huang, H.-Y., Li, S.-H., Yu, S.-C., Chou, F.-F., Tzeng, C.-C., Hu, T.-H., Uen, Y.-H., Tian, Y.-F., Wang, Y.-H., Fang, F.-M., Huang, W.-W., Wei, Y.-C., Wu, J.-M., Li, C.-F.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 754 KB

english, 2009

6

Circulating Tumor Cell as a Diagnostic Marker in Primary Lung Cancer

Tanaka, F., Yoneda, K., Kondo, N., Hashimoto, M., Takuwa, T., Matsumoto, S., Okumura, Y., Rahman, S., Tsubota, N., Tsujimura, T., Kuribayashi, K., Fukuoka, K., Nakano, T., Hasegawa, S.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 687 KB

english, 2009

7

Randomized Biomarker Trial of Anastrozole or Low-Dose Tamoxifen or Their Combination in Subjects with Breast Intraepithelial Neoplasia

Bonanni, B., Serrano, D., Gandini, S., Guerrieri-Gonzaga, A., Johansson, H., Macis, D., Cazzaniga, M., Luini, A., Cassano, E., Oldani, S., Lien, E. A., Pelosi, G., Decensi, A.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 158 KB

english, 2009

8

PIK3CA Mutations Predict Local Recurrences in Rectal Cancer Patients

He, Y., Van't Veer, L. J., Mikolajewska-Hanclich, I., van Velthuysen, M.-L. F., Zeestraten, E. C.M., Nagtegaal, I. D., van de Velde, C. J.H., Marijnen, C. A.M.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 344 KB

english, 2009

9

Could Antitumor Activity of Curcumin in Patients Be due to Its Metabolites? A Response

Dhillon, N., Sung, B., Kurzrock, R., Aggarwal, B. B.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 154 KB

english, 2009

10

DNA Variants in Region for Noncoding Interfering Transcript of Dihydrofolate Reductase Gene and Outcome in Childhood Acute Lymphoblastic Leukemia

Al-Shakfa, F., Dulucq, S., Brukner, I., Milacic, I., Ansari, M., Beaulieu, P., Moghrabi, A., Laverdiere, C., Sallan, S. E., Silverman, L. B., Neuberg, D., Kutok, J. L., Sinnett, D., Krajinovic, M.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 509 KB

english, 2009

11

Getting Knit-PI3Ky: PIK3CA Mutation Status to Direct Multimodality Therapy?

Myers, A. P., Meyerhardt, J. A., Cantley, L. C.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 173 KB

english, 2009

12

A Genomic Approach to Improve Prognosis and Predict Therapeutic Response in Chronic Lymphocytic Leukemia

Friedman, D. R., Weinberg, J. B., Barry, W. T., Goodman, B. K., Volkheimer, A. D., Bond, K. M., Chen, Y., Jiang, N., Moore, J. O., Gockerman, J. P., Diehl, L. F., Decastro, C. M., Potti, A., Nevins, J

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 504 KB

english, 2009

13

Snail Promotes CXCR2 Ligand-Dependent Tumor Progression in Non-Small Cell Lung Carcinoma

Yanagawa, J., Walser, T. C., Zhu, L. X., Hong, L., Fishbein, M. C., Mah, V., Chia, D., Goodglick, L., Elashoff, D. A., Luo, J., Magyar, C. E., Dohadwala, M., Lee, J. M., St. John, M. A., Strieter, R.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 753 KB

english, 2009

14

Mechanisms of Sunitinib Resistance in Gastrointestinal Stromal Tumors Harboring KITAY502-3ins Mutation: An In vitro Mutagenesis Screen for Drug Resistance

Guo, T., Hajdu, M., Agaram, N. P., Shinoda, H., Veach, D., Clarkson, B. D., Maki, R. G., Singer, S., DeMatteo, R. P., Besmer, P., Antonescu, C. R.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 642 KB

english, 2009

15

T-Cell Responses to Cyclin B1 Are Not Restricted to p53-Overexpressing Tumors

von Bergwelt-Baildon, M. S., Shimabukuro-Vornhagen, A., Klein-Gonzalez, N., Kondo, E.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 111 KB

english, 2009

16

Electrocardiographic Characterization of the QTc Interval in Patients with Advanced Solid Tumors: Pharmacokinetic- Pharmacodynamic Evaluation of Sunitinib

Bello, C. L., Mulay, M., Huang, X., Patyna, S., Dinolfo, M., Levine, S., Van Vugt, A., Toh, M., Baum, C., Rosen, L.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 265 KB

english, 2009

17

A Novel Toll-Like Receptor 9 Agonist Cooperates with Trastuzumab in Trastuzumab-Resistant Breast Tumors through Multiple Mechanisms of Action

Damiano, V., Garofalo, S., Rosa, R., Bianco, R., Caputo, R., Gelardi, T., Merola, G., Racioppi, L., Garbi, C., Kandimalla, E. R., Agrawal, S., Tortora, G.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 463 KB

english, 2009

18

Deregulated GSK3 Sustains Gastrointestinal Cancer Cells Survival by Modulating Human Telomerase Reverse Transcriptase and Telomerase

Mai, W., Kawakami, K., Shakoori, A., Kyo, S., Miyashita, K., Yokoi, K., Jin, M., Shimasaki, T., Motoo, Y., Minamoto, T.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 1.08 MB

english, 2009

19

A Single Supratherapeutic Dose of Vorinostat Does Not Prolong the QTc Interval in Patients with Advanced Cancer

Munster, P. N., Rubin, E. H., Van Belle, S., Friedman, E., Patterson, J. K., Van Dyck, K., Li, X., Comisar, W., Chodakewitz, J. A., Wagner, J. A., Iwamoto, M.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 220 KB

english, 2009

20

NKG2D Ligand Expression in Human Colorectal Cancer Reveals Associations with Prognosis and Evidence for Immunoediting

McGilvray, R. W., Eagle, R. A., Watson, N. F.S., Al-Attar, A., Ball, G., Jafferji, I., Trowsdale, J., Durrant, L. G.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 496 KB

english, 2009

21

Survivin as a Prognostic Marker for Urothelial Carcinoma of the Bladder: A Multicenter External Validation Study

Shariat, S. F., Karakiewicz, P. I., Godoy, G., Karam, J. A., Ashfaq, R., Fradet, Y., Isbarn, H., Montorsi, F., Jeldres, C., Bastian, P. J., Nielsen, M. E., Muller, S. C., Sagalowsky, A. I., Lotan, Y.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 447 KB

english, 2009

22

Tumor-Derived Tissue Factor-Bearing Microparticles Are Associated With Venous Thromboembolic Events in Malignancy

Zwicker, J. I., Liebman, H. A., Neuberg, D., Lacroix, R., Bauer, K. A., Furie, B. C., Furie, B.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 647 KB

english, 2009

23

Reciprocal Regulation of c-Src and STAT3 in Non-Small Cell Lung Cancer

Byers, L. A., Sen, B., Saigal, B., Diao, L., Wang, J., Nanjundan, M., Cascone, T., Mills, G. B., Heymach, J. V., Johnson, F. M.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 692 KB

english, 2009

24

Effect of Granulocyte/Macrophage Colony-Stimulating Factor on Circulating CD8+ and CD4+ T-Cell Responses to a Multipeptide Melanoma Vaccine: Outcome of a Multicenter Randomized Trial

Slingluff, C. L., Petroni, G. R., Olson, W. C., Smolkin, M. E., Ross, M. I., Haas, N. B., Grosh, W. W., Boisvert, M. E., Kirkwood, J. M., Chianese-Bullock, K. A.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 601 KB

english, 2009

25

Effect of Granulocyte/Macrophage Colony-Stimulating Factor on Vaccination with an Allogeneic Whole-Cell Melanoma Vaccine

Faries, M. B., Hsueh, E. C., Ye, X., Hoban, M., Morton, D. L.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 422 KB

english, 2009

26

Epidermal Growth Factor Receptor Is Required for Colonic Tumor Promotion by Dietary Fat in the Azoxymethane/Dextran Sulfate Sodium Model: Roles of Transforming Growth Factor- and PTGS2

Dougherty, U., Cerasi, D., Taylor, I., Kocherginsky, M., Tekin, U., Badal, S., Aluri, L., Sehdev, A., Cerda, S., Mustafi, R., Delgado, J., Joseph, L., Zhu, H., Hart, J., Threadgill, D., Fichera, A., B

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 557 KB

english, 2009

27

Microarray-Based Determination of Estrogen Receptor, Progesterone Receptor, and HER2 Receptor Status in Breast Cancer

Roepman, P., Horlings, H. M., Krijgsman, O., Kok, M., Bueno-de-Mesquita, J. M., Bender, R., Linn, S. C., Glas, A. M., van de Vijver, M. J.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 473 KB

english, 2009

28

Production of Interferon- -Inducible Protein-10 and Its Role as an Autocrine Invasion Factor in Nasal Natural Killer/T-Cell Lymphoma Cells

Moriai, S., Takahara, M., Ogino, T., Nagato, T., Kishibe, K., Ishii, H., Katayama, A., Shimizu, N., Harabuchi, Y.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 542 KB

english, 2009

29

Differential Cellular Responses to Prolonged LDR-IR in MLH1-Proficient and MLH1-Deficient Colorectal Cancer HCT116 Cells

Yan, T., Seo, Y., Kinsella, T. J.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 983 KB

english, 2009

30

CD8 T-Cell Responses Against Cyclin B1

Andersen, R. S., Sorensen, R. B., Andersen, M. H., Straten, P. t.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 121 KB

english, 2009

31

Subsets of Very Low Risk Wilms Tumor Show Distinctive Gene Expression, Histologic, and Clinical Features

Sredni, S. T., Gadd, S., Huang, C.-C., Breslow, N., Grundy, P., Green, D. M., Dome, J. S., Shamberger, R. C., Beckwith, J. B., Perlman, E. J.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 782 KB

english, 2009

32

Intratumoral Expression of Mature Human Neutrophil Peptide-1 Mediates Antitumor Immunity in Mice

Wang, Y.-s., Li, D., Shi, H.-s., Wen, Y.-j., Yang, L., Xu, N., Chen, X.-c., Chen, X., Chen, P., Li, J., Deng, H.-x., Wang, C.-t., Xie, G., Huang, S., Mao, Y.-q., Chen, L.-j., Zhao, X., Wei, Y.-q.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 686 KB

english, 2009

33

Comprehensive Genomic Analysis Reveals Clinically Relevant Molecular Distinctions between Thymic Carcinomas and Thymomas

Girard, N., Shen, R., Guo, T., Zakowski, M. F., Heguy, A., Riely, G. J., Huang, J., Lau, C., Lash, A. E., Ladanyi, M., Viale, A., Antonescu, C. R., Travis, W. D., Rusch, V. W., Kris, M. G., Pao, W.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 701 KB

english, 2009

34

Phase I/II Trial of Bevacizumab and Radiotherapy for Locally Advanced Inoperable Colorectal Cancer: Vasculature-Independent Radiosensitizing Effect of Bevacizumab

Koukourakis, M. I., Giatromanolaki, A., Sheldon, H., Buffa, F. M., Kouklakis, G., Ragoussis, I., Sivridis, E., Harris, A. L.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 503 KB

english, 2009

35

Partial CD4 Depletion Reduces Regulatory T Cells Induced by Multiple Vaccinations and Restores Therapeutic Efficacy

LaCelle, M. G., Jensen, S. M., Fox, B. A.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 427 KB

english, 2009

36

Lysine 63 Polyubiquitination in Immunotherapy and in Cancer-promoting Inflammation

Martinez-Forero, I., Rouzaut, A., Palazon, A., Dubrot, J., Melero, I.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 424 KB

english, 2009

37

Gene Expression Profiling of Paraffin-Embedded Primary Melanoma Using the DASL Assay Identifies Increased Osteopontin Expression as Predictive of Reduced Relapse-Free Survival

Conway, C., Mitra, A., Jewell, R., Randerson-Moor, J., Lobo, S., Nsengimana, J., Edward, S., Sanders, D. S., Cook, M., Powell, B., Boon, A., Elliott, F., de Kort, F., Knowles, M. A., Bishop, D. T., Ne

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 331 KB

english, 2009

38

Phase II Study of Androgen Synthesis Inhibition with Ketoconazole, Hydrocortisone, and Dutasteride in Asymptomatic Castration-Resistant Prostate Cancer

Taplin, M.-E., Regan, M. M., Ko, Y.-J., Bubley, G. J., Duggan, S. E., Werner, L., Beer, T. M., Ryan, C. W., Mathew, P., Tu, S.-M., Denmeade, S. R., Oh, W. K., Sartor, O., Mantzoros, C. S., Rittmaster,

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 208 KB

english, 2009

39

Immunostimulation Versus Immunosuppression after Multiple Vaccinations: the Woes of Therapeutic Vaccine Development

Eggermont, A. M.M.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 208 KB

english, 2009

40

Correction: EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 104 KB

english, 2009

41

Correction: Unique Clinicopathologic Features Characterize ALK-Rearranged Lung Adenocarcinoma in the Western Population

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 101 KB

english, 2009

42

Activation of Host Wound Responses in Breast Cancer Microenvironment

Troester, M. A., Lee, M. H., Carter, M., Fan, C., Cowan, D. W., Perez, E. R., Pirone, J. R., Perou, C. M., Jerry, D. J., Schneider, S. S.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 833 KB

english, 2009

43

Human Papillomavirus in Head and Neck Cancer: Its Role in Pathogenesis and Clinical Implications

Chung, C. H., Gillison, M. L.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 244 KB

english, 2009

44

Combined Inhibition of Janus Kinase 1/2 for the Treatment of JAK2V617F-Driven Neoplasms: Selective Effects on Mutant Cells and Improvements in Measures of Disease Severity

Liu, P. C.C., Caulder, E., Li, J., Waeltz, P., Margulis, A., Wynn, R., Becker-Pasha, M., Li, Y., Crowgey, E., Hollis, G., Haley, P., Sparks, R. B., Combs, A. P., Rodgers, J. D., Burn, T. C., Vaddi, K.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 666 KB

english, 2009

45

Role of Class 3 Semaphorins and Their Receptors in Tumor Growth and Angiogenesis

Gaur, P., Bielenberg, D. R., Samuel, S., Bose, D., Zhou, Y., Gray, M. J., Dallas, N. A., Fan, F., Xia, L., Lu, J., Ellis, L. M.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 340 KB

english, 2009

46

Phase I Trial of a Combination of the Multikinase Inhibitor Sorafenib and the Farnesyltransferase Inhibitor Tipifarnib in Advanced Malignancies

Hong, D. S., Sebti, S. M., Newman, R. A., Blaskovich, M. A., Ye, L., Gagel, R. F., Moulder, S., Wheler, J. J., Naing, A., Tannir, N. M., Ng, C. S., Sherman, S. I., El Naggar, A. K., Khan, R., Trent, J

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 312 KB

english, 2009

47

A Multimarker Prognostic Assay for Primary Cutaneous Melanoma

Kashani-Sabet, M., Venna, S., Nosrati, M., Rangel, J., Sucker, A., Egberts, F., Baehner, F. L., Simko, J., Leong, S. P.L., Haqq, C., Hauschild, A., Schadendorf, D., Miller, J. R., Sagebiel, R. W.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 194 KB

english, 2009

48

JNJ-26481585, a Novel "Second-Generation" Oral Histone Deacetylase Inhibitor, Shows Broad-Spectrum Preclinical Antitumoral Activity

Arts, J., King, P., Marien, A., Floren, W., Belien, A., Janssen, L., Pilatte, I., Roux, B., Decrane, L., Gilissen, R., Hickson, I., Vreys, V., Cox, E., Bol, K., Talloen, W., Goris, I., Andries, L., Du

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 1.04 MB

english, 2009

49

The Neuropharmacokinetics of Temozolomide in Patients with Resectable Brain Tumors: Potential Implications for the Current Approach to Chemoradiation

Portnow, J., Badie, B., Chen, M., Liu, A., Blanchard, S., Synold, T. W.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 337 KB

english, 2009