Volume 16; Issue 2

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Clinical Cancer Research
Volume 16; Issue 2

Clinical Cancer Research

Volume 16; Issue 2

1

GSK690693 Delays Tumor Onset and Progression in Genetically Defined Mouse Models Expressing Activated Akt

Altomare, D. A., Zhang, L., Deng, J., Di Cristofano, A., Klein-Szanto, A. J., Kumar, R., Testa, J. R.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 902 KB

english, 2010

2

New Insights into Checkpoint Kinase 1 in the DNA Damage Response Signaling Network

Dai, Y., Grant, S.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 381 KB

english, 2010

3

Targeting Polo-like Kinase in Cancer Therapy

Degenhardt, Y., Lampkin, T.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 341 KB

english, 2010

4

The Cross-Validated Adaptive Signature Design

Freidlin, B., Jiang, W., Simon, R.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 231 KB

english, 2010

5

Activities of SYK and PLC 2 Predict Apoptotic Response of CLL Cells to SRC Tyrosine Kinase Inhibitor Dasatinib

Song, Z., Lu, P., Furman, R. R., Leonard, J. P., Martin, P., Tyrell, L., Lee, F. Y., Knowles, D. M., Coleman, M., Wang, Y. L.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 984 KB

english, 2010

6

Activity of the Kinesin Spindle Protein Inhibitor Ispinesib (SB-715992) in Models of Breast Cancer

Purcell, J. W., Davis, J., Reddy, M., Martin, S., Samayoa, K., Vo, H., Thomsen, K., Bean, P., Kuo, W. L., Ziyad, S., Billig, J., Feiler, H. S., Gray, J. W., Wood, K. W., Cases, S.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 1.01 MB

english, 2010

7

Mechanisms of Ascorbate-Induced Cytotoxicity in Pancreatic Cancer

Du, J., Martin, S. M., Levine, M., Wagner, B. A., Buettner, G. R., Wang, S.-h., Taghiyev, A. F., Du, C., Knudson, C. M., Cullen, J. J.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 691 KB

english, 2010

8

Integration of DNA Copy Number Alterations and Prognostic Gene Expression Signatures in Breast Cancer Patients

Horlings, H. M., Lai, C., Nuyten, D. S.A., Halfwerk, H., Kristel, P., van Beers, E., Joosse, S. A., Klijn, C., Nederlof, P. M., Reinders, M. J.T., Wessels, L. F.A., van de Vijver, M. J.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 577 KB

english, 2010

9

MicroRNA Expression Differentiates Histology and Predicts Survival of Lung Cancer

Landi, M. T., Zhao, Y., Rotunno, M., Koshiol, J., Liu, H., Bergen, A. W., Rubagotti, M., Goldstein, A. M., Linnoila, I., Marincola, F. M., Tucker, M. A., Bertazzi, P. A., Pesatori, A. C., Caporaso, N.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 610 KB

english, 2010

10

A CYP3A4 Phenotype-Based Dosing Algorithm for Individualized Treatment of Irinotecan

van der Bol, J. M., Mathijssen, R. H.J., Creemers, G.-J. M., Planting, A. S.Th., Loos, W. J., Wiemer, E. A.C., Friberg, L. E., Verweij, J., Sparreboom, A., de Jong, F. A.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 309 KB

english, 2010

11

Mechanisms of Inactivation of PTCH1 Gene in Nevoid Basal Cell Carcinoma Syndrome: Modification of the Two-Hit Hypothesis

Pan, S., Dong, Q., Sun, L.-S., Li, T.-J.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 486 KB

english, 2010

12

Romidepsin and Belinostat Synergize the Antineoplastic Effect of Bortezomib in Mantle Cell Lymphoma

Paoluzzi, L., Scotto, L., Marchi, E., Zain, J., Seshan, V. E., O'Connor, O. A.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 842 KB

english, 2010

13

Interleukin 13 Mediates Signal Transduction through Interleukin 13 Receptor 2 in Pancreatic Ductal Adenocarcinoma: Role of IL-13 Pseudomonas Exotoxin in Pancreatic Cancer Therapy

Shimamura, T., Fujisawa, T., Husain, S. R., Joshi, B., Puri, R. K.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 1.15 MB

english, 2010

14

Improved Potency and Selectivity of an Oncolytic E1ACR2 and E1B19K Deleted Adenoviral Mutant in Prostate and Pancreatic Cancers

Oberg, D., Yanover, E., Adam, V., Sweeney, K., Costas, C., Lemoine, N. R., Hallden, G.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 820 KB

english, 2010

15

Development of Molecularly Targeted Therapies in Hepatocellular Carcinoma: Where Do We Go Now?

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 235 KB

english, 2010

16

ERBB2 Induces an Antiapoptotic Expression Pattern of Bcl-2 Family Members in Node-Negative Breast Cancer

Petry, I. B., Fieber, E., Schmidt, M., Gehrmann, M., Gebhard, S., Hermes, M., Schormann, W., Selinski, S., Freis, E., Schwender, H., Brulport, M., Ickstadt, K., Rahnenfuhrer, J., Maccoux, L., West, J.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 328 KB

english, 2010

17

Tumor O6-methylguanine-DNA Methyltransferase Inactivation by Oral Lomeguatrib

Watson, A. J., Sabharwal, A., Thorncroft, M., McGown, G., Kerr, R., Bojanic, S., Soonawalla, Z., King, A., Miller, A., Waller, S., Leung, H., Margison, G. P., Middleton, M. R.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 209 KB

english, 2010

18

Antitumor Effect of NK012, a 7-Ethyl-10-Hydroxycamptothecin-Incorporating Polymeric Micelle, on U87MG Orthotopic Glioblastoma in Mice Compared with Irinotecan Hydrochloride in Combination with Bevacizumab

Kuroda, J.-i., Kuratsu, J.-i., Yasunaga, M., Koga, Y., Kenmotsu, H., Sugino, T., Matsumura, Y.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 1.01 MB

english, 2010

19

DNA Microarrays Are Predictive of Cancer Prognosis: A Re-evaluation

Fan, X., Shi, L., Fang, H., Cheng, Y., Perkins, R., Tong, W.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 461 KB

english, 2010

20

Prospective Comparison of Clinical and Genomic Multivariate Predictors of Response to Neoadjuvant Chemotherapy in Breast Cancer

Lee, J. K., Coutant, C., Kim, Y.-C., Qi, Y., Theodorescu, D., Symmans, W. F., Baggerly, K., Rouzier, R., Pusztai, L.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 313 KB

english, 2010

21

Expression of Mutated IGHV3-23 Genes in Chronic Lymphocytic Leukemia Identifies a Disease Subset with Peculiar Clinical and Biological Features

Bomben, R., Dal-Bo, M., Benedetti, D., Capello, D., Forconi, F., Marconi, D., Bertoni, F., Maffei, R., Laurenti, L., Rossi, D., Del Principe, M. I., Luciano, F., Sozzi, E., Cattarossi, I., Zucchetto,

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 449 KB

english, 2010

22

Methylation Induced Gene Silencing of HtrA3 in Smoking-Related Lung Cancer

Beleford, D., Liu, Z., Rattan, R., Quagliuolo, L., Boccellino, M., Baldi, A., Maguire, J., Staub, J., Molina, J., Shridhar, V.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 644 KB

english, 2010

23

A Unifying Microenvironment Model in Follicular Lymphoma: Outcome Is Predicted by Programmed Death-1-Positive, Regulatory, Cytotoxic, and Helper T Cells and Macrophages

Wahlin, B. E., Aggarwal, M., Montes-Moreno, S., Gonzalez, L. F., Roncador, G., Sanchez-Verde, L., Christensson, B., Sander, B., Kimby, E.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 1.10 MB

english, 2010

24

Immunoglobulin Heavy Chain Variable Gene Usage and (Super)-antigen Drive in Chronic Lymphocytic Leukemia

Buhler, A., Zenz, T., Stilgenbauer, S.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 276 KB

english, 2010

25

Angiopoietin-2 Promotes Disease Progression of Neuroendocrine Tumors

Detjen, K. M., Rieke, S., Deters, A., Schulz, P., Rexin, A., Vollmer, S., Hauff, P., Wiedenmann, B., Pavel, M., Scholz, A.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 557 KB

english, 2010

26

Glioma-Associated Cancer-Initiating Cells Induce Immunosuppression

Wei, J., Barr, J., Kong, L.-Y., Wang, Y., Wu, A., Sharma, A. K., Gumin, J., Henry, V., Colman, H., Sawaya, R., Lang, F. F., Heimberger, A. B.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 576 KB

english, 2010

27

Identification of Cyclooxygenase-2 as a Major Actor of the Transcriptomic Adaptation of Endothelial and Tumor Cells to Cyclic Hypoxia: Effect on Angiogenesis and Metastases

Daneau, G., Boidot, R., Martinive, P., Feron, O.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 701 KB

english, 2010

28

Antibodies to TWEAK Receptor Inhibit Human Tumor Growth through Dual Mechanisms

Culp, P. A., Choi, D., Zhang, Y., Yin, J., Seto, P., Ybarra, S. E., Su, M., Sho, M., Steinle, R., Wong, M. H.L., Evangelista, F., Grove, J., Cardenas, M., James, M., Hsi, E. D., Chao, D. T., Powers, D

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 603 KB

english, 2010

29

Reduced DNA Repair Capacity for Removing Tobacco Carcinogen-Induced DNA Adducts Contributes to Risk of Head and Neck Cancer but not Tumor Characteristics

Wang, L.-E, Hu, Z., Sturgis, E. M., Spitz, M. R., Strom, S. S., Amos, C. I., Guo, Z., Qiao, Y., Gillenwater, A. M., Myers, J. N., Clayman, G. L., Weber, R. S., El-Naggar, A. K., Mao, L., Lippman, S. M

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 479 KB

english, 2010

30

Vandetanib, Designed to Inhibit VEGFR2 and EGFR Signaling, Had No Clinical Activity as Monotherapy for Recurrent Ovarian Cancer and No Detectable Modulation of VEGFR2

Annunziata, C. M., Walker, A. J., Minasian, L., Yu, M., Kotz, H., Wood, B. J., Calvo, K., Choyke, P., Kimm, D., Steinberg, S. M., Kohn, E. C.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 315 KB

english, 2010

31

Phase I Study of Recombinant Human Interleukin-7 Administration in Subjects with Refractory Malignancy

Sportes, C., Babb, R. R., Krumlauf, M. C., Hakim, F. T., Steinberg, S. M., Chow, C. K., Brown, M. R., Fleisher, T. A., Noel, P., Maric, I., Stetler-Stevenson, M., Engel, J., Buffet, R., Morre, M., Ama

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 685 KB

english, 2010

32

Individualizing Dosing of Irinotecan

Ratain, M. J., Innocenti, F.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 196 KB

english, 2010

33

Time to Treatment Response in Patients with Follicular Lymphoma Treated with Bortezomib Is Longer Compared with Other Histologic Subtypes

O'Connor, O. A., Portlock, C., Moskowitz, C., Hamlin, P., Straus, D., Gerecitano, J., Gonen, M., Dumitrescu, O., Sarasohn, D., Butos, J., Neylon, E., Mac-Gregor Cortelli, B., Blumel, S., Evens, A. M.,

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 425 KB

english, 2010

34

NVP-BEZ235 as a New Therapeutic Option for Sarcomas

Manara, M. C., Nicoletti, G., Zambelli, D., Ventura, S., Guerzoni, C., Landuzzi, L., Lollini, P.-L., Maira, S.-M., Garcia-Echeverria, C., Mercuri, M., Picci, P., Scotlandi, K.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 833 KB

english, 2010

35

Safety, Pharmacokinetics, and Pharmacodynamics of AMG 102, a Fully Human Hepatocyte Growth Factor-Neutralizing Monoclonal Antibody, in a First-in-Human Study of Patients with Advanced Solid Tumors

Gordon, M. S., Sweeney, C. J., Mendelson, D. S., Eckhardt, S. G., Anderson, A., Beaupre, D. M., Branstetter, D., Burgess, T. L., Coxon, A., Deng, H., Kaplan-Lefko, P., Leitch, I. M., Oliner, K. S., Ya

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 755 KB

english, 2010

36

A Phase I Study of 7-t-Butyldimethylsilyl-10-Hydroxycamptothecin in Adult Patients with Refractory or Metastatic Solid Malignancies

Arnold, S. M., Rinehart, J. J., Tsakalozou, E., Eckardt, J. R., Fields, S. Z., Shelton, B. J., DeSimone, P. A., Kee, B. K., Moscow, J. A., Leggas, M.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 308 KB

english, 2010

37

Analysis of Genetic Variants in Never-Smokers with Lung Cancer Facilitated by an Internet-Based Blood Collection Protocol: A Preliminary Report

Girard, N., Lou, E., Azzoli, C. G., Reddy, R., Robson, M., Harlan, M., Orlow, I., Yatabe, Y., Nafa, K., Ladanyi, M., Viale, A., Kris, M. G., Riely, G., Miller, V., Klein, R. J., Matsuo, K., Pao, W.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 528 KB

english, 2010

38

Identification of Markers of Taxane Sensitivity Using Proteomic and Genomic Analyses of Breast Tumors from Patients Receiving Neoadjuvant Paclitaxel and Radiation

Bauer, J. A., Chakravarthy, A. B., Rosenbluth, J. M., Mi, D., Seeley, E. H., De Matos Granja-Ingram, N., Olivares, M. G., Kelley, M. C., Mayer, I. A., Meszoely, I. M., Means-Powell, J. A., Johnson, K.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 761 KB

english, 2010

39

HER2-Specific T Cells Target Primary Glioblastoma Stem Cells and Induce Regression of Autologous Experimental Tumors

Ahmed, N., Salsman, V. S., Kew, Y., Shaffer, D., Powell, S., Zhang, Y. J., Grossman, R. G., Heslop, H. E., Gottschalk, S.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 1.09 MB

english, 2010

40

Phase II Trial of Ixabepilone Administered Daily for Five Days in Children and Young Adults with Refractory Solid Tumors: A Report from the Children's Oncology Group

Jacobs, S., Fox, E., Krailo, M., Hartley, G., Navid, F., Wexler, L., Blaney, S. M., Goodwin, A., Goodspeed, W., Balis, F. M., Adamson, P. C., Widemann, B. C.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 175 KB

english, 2010

41

Accurate Classification of Non-Small Cell Lung Carcinoma Using a Novel MicroRNA-Based Approach

Bishop, J. A., Benjamin, H., Cholakh, H., Chajut, A., Clark, D. P., Westra, W. H.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 862 KB

english, 2010

42

Secretory Leukocyte Protease Inhibitor Antagonizes Paclitaxel in Ovarian Cancer Cells

Rasool, N., LaRochelle, W., Zhong, H., Ara, G., Cohen, J., Kohn, E. C.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 695 KB

english, 2010