Volume 16; Issue 3

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Clinical Cancer Research
Volume 16; Issue 3

Clinical Cancer Research

Volume 16; Issue 3

1

Prevalence and Heterogeneity of KRAS, BRAF, and PIK3CA Mutations in Primary Colorectal Adenocarcinomas and Their Corresponding Metastases

Baldus, S. E., Schaefer, K.-L., Engers, R., Hartleb, D., Stoecklein, N. H., Gabbert, H. E.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 494 KB

english, 2010

2

Plasma EBV DNA Clearance Rate as a Novel Prognostic Marker for Metastatic/Recurrent Nasopharyngeal Carcinoma

Wang, W.-Y., Twu, C.-W., Chen, H.-H., Jan, J.-S., Jiang, R.-S., Chao, J. Y.C., Liang, K.-L., Chen, K.-W., Wu, C.-T., Lin, J.-C.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 595 KB

english, 2010

3

Aggressive Chronic Lymphocytic Leukemia with Elevated Genomic Complexity Is Associated with Multiple Gene Defects in the Response to DNA Double-Strand Breaks

Ouillette, P., Fossum, S., Parkin, B., Ding, L., Bockenstedt, P., Al-Zoubi, A., Shedden, K., Malek, S. N.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 643 KB

english, 2010

4

MiR-222 Overexpression Confers Cell Migratory Advantages in Hepatocellular Carcinoma through Enhancing AKT Signaling

Wong, Q. W-L., Ching, A. K-K., Chan, A. W-H., Choy, K.-W., To, K.-F., Lai, P. B-S., Wong, N.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 606 KB

english, 2010

5

Hepatitis C Virus Proteins Modulate MicroRNA Expression and Chemosensitivity in Malignant Hepatocytes

Braconi, C., Valeri, N., Gasparini, P., Huang, N., Taccioli, C., Nuovo, G., Suzuki, T., Croce, C. M., Patel, T.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 527 KB

english, 2010

6

IGFBP2 and IGFBP3 Protein Expressions in Human Breast Cancer: Association with Hormonal Factors and Obesity

Probst-Hensch, N. M., Steiner, J. H.B., Schraml, P., Varga, Z., Zurrer-Hardi, U., Storz, M., Korol, D., Fehr, M. K., Fink, D., Pestalozzi, B. C., Lutolf, U. M., Theurillat, J.-P., Moch, H.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 353 KB

english, 2010

7

18F-Fluorodeoxyglucose Positron Emission Tomography Predicts Survival of Patients with Neuroendocrine Tumors

Binderup, T., Knigge, U., Loft, A., Federspiel, B., Kjaer, A.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 299 KB

english, 2010

8

A Degenerate HLA-DR Epitope Pool of HER-2/neu Reveals a Novel In vivo Immunodominant Epitope, HER-2/neu88-102

Karyampudi, L., Formicola, C., Erskine, C. L., Maurer, M. J., Ingle, J. N., Krco, C. J., Wettstein, P. J., Kalli, K. R., Fikes, J. D., Beebe, M., Hartmann, L. C., Disis, M. L., Ferrone, S., Ishioka, G

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 357 KB

english, 2010

9

Validation of SAG/RBX2/ROC2 E3 Ubiquitin Ligase as an Anticancer and Radiosensitizing Target

Jia, L., Yang, J., Hao, X., Zheng, M., He, H., Xiong, X., Xu, L., Sun, Y.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 763 KB

english, 2010

10

Efficacy of Combining GMX1777 with Radiation Therapy for Human Head and Neck Carcinoma

Kato, H., Ito, E., Shi, W., Alajez, N. M., Yue, S., Lee, C., Chan, N., Bhogal, N., Coackley, C. L., Vines, D., Green, D., Waldron, J., Gullane, P., Bristow, R., Liu, F.-F.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 1.31 MB

english, 2010

11

Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate

Okeley, N. M., Miyamoto, J. B., Zhang, X., Sanderson, R. J., Benjamin, D. R., Sievers, E. L., Senter, P. D., Alley, S. C.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 645 KB

english, 2010

12

Endometrial Profile of Tamoxifen and Low-Dose Estradiol Combination Therapy

Wood, C. E., Kaplan, J. R., Fontenot, M. B., Williams, J. K., Cline, J. M.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 594 KB

english, 2010

13

TKTL1 Is Activated by Promoter Hypomethylation and Contributes to Head and Neck Squamous Cell Carcinoma Carcinogenesis through Increased Aerobic Glycolysis and HIF1 Stabilization

Sun, W., Liu, Y., Glazer, C. A., Shao, C., Bhan, S., Demokan, S., Zhao, M., Rudek, M. A., Ha, P. K., Califano, J. A.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 404 KB

english, 2010

14

Clinical Pharmacokinetics of Amifostine and WR1065 in Pediatric Patients with Medulloblastoma

McKibbin, T., Panetta, J. C., Fouladi, M., Gajjar, A., Bai, F., Okcu, M. F., Stewart, C. F.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 384 KB

english, 2010

15

Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase Inhibition Results in Biphasic Alteration of Epidermal Homeostasis with Keratinocytic Apoptosis and Pigmentation Disorders

Schad, K., Baumann Conzett, K., Zipser, M. C., Enderlin, V., Kamarashev, J., French, L. E., Dummer, R.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 311 KB

english, 2010

16

Nuclear Factor- B and Tumor-Associated Macrophages

Mancino, A., Lawrence, T.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 294 KB

english, 2010

17

Heterogeneity for Stem Cell-Related Markers According to Tumor Subtype and Histologic Stage in Breast Cancer

Park, S. Y., Lee, H. E., Li, H., Shipitsin, M., Gelman, R., Polyak, K.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 979 KB

english, 2010

18

Delta-Like Ligand 4 Plays a Critical Role in Pericyte/Vascular Smooth Muscle Cell Formation during Vasculogenesis and Tumor Vessel Expansion in Ewing's Sarcoma

Schadler, K. L., Zweidler-McKay, P. A., Guan, H., Kleinerman, E. S.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 802 KB

english, 2010

19

Inherited Determinants of Ovarian Cancer Survival

Goode, E. L., Maurer, M. J., Sellers, T. A., Phelan, C. M., Kalli, K. R., Fridley, B. L., Vierkant, R. A., Armasu, S. M., White, K. L., Keeney, G. L., Cliby, W. A., Rider, D. N., Kelemen, L. E., Jones

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 520 KB

english, 2010

20

Application of a Time-Varying Covariate Model to the Analysis of CA 19-9 as Serum Biomarker in Patients with Advanced Pancreatic Cancer

Boeck, S., Haas, M., Laubender, R. P., Kullmann, F., Klose, C., Bruns, C. J., Wilkowski, R., Stieber, P., Holdenrieder, S., Buchner, H., Mansmann, U., Heinemann, V.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 260 KB

english, 2010

21

Phase II Trial of Tremelimumab (CP-675,206) in Patients with Advanced Refractory or Relapsed Melanoma

Kirkwood, J. M., Lorigan, P., Hersey, P., Hauschild, A., Robert, C., McDermott, D., Marshall, M. A., Gomez-Navarro, J., Liang, J. Q., Bulanhagui, C. A.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 215 KB

english, 2010

22

Associations between Radiocurability and Interstitial Fluid Pressure in Human Tumor Xenografts without Hypoxic Tissue

Rofstad, E. K., Ruud, E.-B. M., Mathiesen, B., Galappathi, K.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 248 KB

english, 2010

23

Targeting Vascular Endothelial Growth Factor Receptor in Thyroid Cancer: The Intracellular and Extracellular Implications

Keefe, S. M., Cohen, M. A., Brose, M. S.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 266 KB

english, 2010

24

Radiosensitization of Epidermal Growth Factor Receptor/HER2-Positive Pancreatic Cancer Is Mediated by Inhibition of Akt Independent of Ras Mutational Status

Kimple, R. J., Vaseva, A. V., Cox, A. D., Baerman, K. M., Calvo, B. F., Tepper, J. E., Shields, J. M., Sartor, C. I.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 438 KB

english, 2010

25

Immunobiological Characterization of Cancer Stem Cells Isolated from Glioblastoma Patients

Di Tomaso, T., Mazzoleni, S., Wang, E., Sovena, G., Clavenna, D., Franzin, A., Mortini, P., Ferrone, S., Doglioni, C., Marincola, F. M., Galli, R., Parmiani, G., Maccalli, C.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 360 KB

english, 2010

26

Clinical and Translational Studies of a Phase II Trial of the Novel Oral Akt Inhibitor Perifosine in Relapsed or Relapsed/Refractory Waldenstrom's Macroglobulinemia

Ghobrial, I. M., Roccaro, A., Hong, F., Weller, E., Rubin, N., Leduc, R., Rourke, M., Chuma, S., Sacco, A., Jia, X., Azab, F., Azab, A. K., Rodig, S., Warren, D., Harris, B., Varticovski, L., Sportell

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 440 KB

english, 2010

27

Targeting the Tumor Microenvironment With Src Kinase Inhibition

Chung, A. S., Ferrara, N.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 117 KB

english, 2010

28

Antitumor Activity of Targeting Src Kinases in Endothelial and Myeloid Cell Compartments of the Tumor Microenvironment

Liang, W., Kujawski, M., Wu, J., Lu, J., Herrmann, A., Loera, S., Yen, Y., Lee, F., Yu, H., Wen, W., Jove, R.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 905 KB

english, 2010

29

Suppression of Liver Tumor Growth and Metastasis by Adiponectin in Nude Mice through Inhibition of Tumor Angiogenesis and Downregulation of Rho Kinase/IFN-Inducible Protein 10/Matrix Metalloproteinase 9 Signaling

Man, K., Ng, K. T.P., Xu, A., Cheng, Q., Lo, C. M., Xiao, J. W., Sun, B. S., Lim, Z. X.H., Cheung, J. S., Wu, E. X., Sun, C. K.W., Poon, R. T.P., Fan, S. T.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 1.16 MB

english, 2010

30

Serum Prognostic Markers in Head and Neck Cancer

Meyer, F., Samson, E., Douville, P., Duchesne, T., Liu, G., Bairati, I.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 257 KB

english, 2010

31

Spatial Analyses Identify the Geographic Source of Patients at a National Cancer Institute Comprehensive Cancer Center

Su, S.-C., Kanarek, N., Fox, M. G., Guseynova, A., Crow, S., Piantadosi, S.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 441 KB

english, 2010

32

Monitoring Drug-Induced H2AX as a Pharmacodynamic Biomarker in Individual Circulating Tumor Cells

Wang, L. H., Pfister, T. D., Parchment, R. E., Kummar, S., Rubinstein, L., Evrard, Y. A., Gutierrez, M. E., Murgo, A. J., Tomaszewski, J. E., Doroshow, J. H., Kinders, R. J.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 815 KB

english, 2010