Volume 17; Issue 4

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Clinical Cancer Research
Volume 17; Issue 4

Clinical Cancer Research

Volume 17; Issue 4

1

Principles and Current Strategies for Targeting Autophagy for Cancer Treatment

Amaravadi, R. K., Lippincott-Schwartz, J., Yin, X.-M., Weiss, W. A., Takebe, N., Timmer, W., DiPaola, R. S., Lotze, M. T., White, E.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 18.24 MB

english, 2011

2

Targeting Wnt Signaling in Colon Cancer Stem Cells

de Sousa, E. M. F., Vermeulen, L., Richel, D., Medema, J. P.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 12.45 MB

english, 2011

3

Serum Biomarker Panels for the Detection of Pancreatic Cancer

Brand, R. E., Nolen, B. M., Zeh, H. J., Allen, P. J., Eloubeidi, M. A., Goldberg, M., Elton, E., Arnoletti, J. P., Christein, J. D., Vickers, S. M., Langmead, C. J., Landsittel, D. P., Whitcomb, D. C.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 564 KB

english, 2011

4

ShRNA-Targeted MAP4K4 Inhibits Hepatocellular Carcinoma Growth

Liu, A.-W., Cai, J., Zhao, X.-L., Jiang, T.-H., He, T.-F., Fu, H.-Q., Zhu, M.-H., Zhang, S.-H.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 719 KB

english, 2011

5

Extended Dose Ipilimumab with a Peptide Vaccine: Immune Correlates Associated with Clinical Benefit in Patients with Resected High-Risk Stage IIIc/IV Melanoma

Sarnaik, A. A., Yu, B., Yu, D., Morelli, D., Hall, M., Bogle, D., Yan, L., Targan, S., Solomon, J., Nichol, G., Yellin, M., Weber, J. S.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 620 KB

english, 2011

6

Carbon Nanotubes Enhance CpG Uptake and Potentiate Antiglioma Immunity

Zhao, D., Alizadeh, D., Zhang, L., Liu, W., Farrukh, O., Manuel, E., Diamond, D. J., Badie, B.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 2.53 MB

english, 2011

7

Tumor Growth Inhibition by Olaparib in BRCA2 Germline-Mutated Patient-Derived Ovarian Cancer Tissue Xenografts

Kortmann, U., McAlpine, J. N., Xue, H., Guan, J., Ha, G., Tully, S., Shafait, S., Lau, A., Cranston, A. N., O'Connor, M. J., Huntsman, D. G., Wang, Y., Gilks, C. B.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 1.61 MB

english, 2011

8

Efficient In vivo Priming by Vaccination with Recombinant NY-ESO-1 Protein and CpG in Antigen Naive Prostate Cancer Patients

Karbach, J., Neumann, A., Atmaca, A., Wahle, C., Brand, K., von Boehmer, L., Knuth, A., Bender, A., Ritter, G., Old, L. J., Jager, E.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 677 KB

english, 2011

9

Tumor Regression and Growth Rates Determined in Five Intramural NCI Prostate Cancer Trials: The Growth Rate Constant as an Indicator of Therapeutic Efficacy

Stein, W. D., Gulley, J. L., Schlom, J., Madan, R. A., Dahut, W., Figg, W. D., Ning, Y.-m., Arlen, P. M., Price, D., Bates, S. E., Fojo, T.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 797 KB

english, 2011

10

Clinical Validation of Colorectal Cancer Biomarkers Identified from Bioinformatics Analysis of Public Expression Data

Jung, Y., Lee, S., Choi, H.-S., Kim, S.-N., Lee, E., Shin, Y., Seo, J., Kim, B., Jung, Y., Kim, W. K., Chun, H.-K., Lee, W. Y., Kim, J.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 672 KB

english, 2011

11

Seamless Phase I-II Trial Design for Assessing Toxicity and Efficacy for Targeted Agents

Hoering, A., LeBlanc, M., Crowley, J.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 435 KB

english, 2011

12

A Multilocus Technique for Risk Evaluation of Patients with Neuroblastoma

Ambros, I. M., Brunner, B., Aigner, G., Bedwell, C., Beiske, K., Benard, J., Bown, N., Combaret, V., Couturier, J., Defferrari, R., Gross, N., Jeison, M., Lunec, J., Marques, B., Martinsson, T., Mazzo

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 983 KB

english, 2011

13

Both Gene Amplification and Allelic Loss Occur at 14q13.3 in Lung Cancer

Harris, T., Pan, Q., Sironi, J., Lutz, D., Tian, J., Sapkar, J., Perez-Soler, R., Keller, S., Locker, J.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 1.23 MB

english, 2011

14

Phase I Dose-Escalation Study of the Novel Antiandrogen BMS-641988 in Patients with Castration-Resistant Prostate Cancer

Rathkopf, D., Liu, G., Carducci, M. A., Eisenberger, M. A., Anand, A., Morris, M. J., Slovin, S. F., Sasaki, Y., Takahashi, S., Ozono, S., Fung, N. K. E., Cheng, S., Gan, J., Gottardis, M., Obermeier,

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 278 KB

english, 2011

15

Polo-Like Kinase 1 is a Therapeutic Target in High-Risk Neuroblastoma

Ackermann, S., Goeser, F., Schulte, J. H., Schramm, A., Ehemann, V., Hero, B., Eggert, A., Berthold, F., Fischer, M.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 800 KB

english, 2011

16

Natural Killer Cells are Scarce in Colorectal Carcinoma Tissue Despite High Levels of Chemokines and Cytokines

Halama, N., Braun, M., Kahlert, C., Spille, A., Quack, C., Rahbari, N., Koch, M., Weitz, J., Kloor, M., Zoernig, I., Schirmacher, P., Brand, K., Grabe, N., Falk, C. S.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 2.22 MB

english, 2011

17

Impact of ABCB1 Allelic Variants on QTc Interval Prolongation

Sissung, T. M., Gardner, E. R., Piekarz, R. L., Howden, R., Chen, X., Woo, S., Franke, R., Clark, J. A., Miller-DeGraff, L., Steinberg, S. M., Venzon, D., Liewehr, D., Kleeberger, S. R., Bates, S. E.,

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 461 KB

english, 2011

18

Preoperative Circulating Tumor Cell Detection Using the Isolation by Size of Epithelial Tumor Cell Method for Patients with Lung Cancer Is a New Prognostic Biomarker

Hofman, V., Bonnetaud, C., Ilie, M. I., Vielh, P., Vignaud, J. M., Flejou, J. F., Lantuejoul, S., Piaton, E., Mourad, N., Butori, C., Selva, E., Poudenx, M., Sibon, S., Kelhef, S., Venissac, N., Jais,

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 653 KB

english, 2011

19

Combination mTOR and IGF-1R Inhibition: Phase I Trial of Everolimus and Figitumumab in Patients with Advanced Sarcomas and Other Solid Tumors

Quek, R., Wang, Q., Morgan, J. A., Shapiro, G. I., Butrynski, J. E., Ramaiya, N., Huftalen, T., Jederlinic, N., Manola, J., Wagner, A. J., Demetri, G. D., George, S.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 441 KB

english, 2011

20

Pathologic Reassessment of Prostate Cancer Surgical Specimens Before Molecular Retrospective Studies

Fromont, G., Validire, P., Prapotnich, D., Rozet, F., Vallancien, G., Cussenot, O., Cathelineau, X.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 294 KB

english, 2011

21

Markers of Pancreatic Cancer: Working Toward Early Detection

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 4.15 MB

english, 2011

22

PIK3CA Mutations May Be Discordant between Primary and Corresponding Metastatic Disease in Breast Cancer

Dupont Jensen, J., Laenkholm, A.-V., Knoop, A., Ewertz, M., Bandaru, R., Liu, W., Hackl, W., Barrett, J. C., Gardner, H.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 588 KB

english, 2011

23

ICER Evokes Dusp1-p38 Pathway Enhancing Chemotherapy Sensitivity in Myeloid Leukemia

Pigazzi, M., Manara, E., Beghin, A., Baron, E., Tregnago, C., Basso, G.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 922 KB

english, 2011

24

Polymorphisms inside MicroRNAs and MicroRNA Target Sites Predict Clinical Outcomes in Prostate Cancer Patients Receiving Androgen-Deprivation Therapy

Bao, B.-Y., Pao, J.-B., Huang, C.-N., Pu, Y.-S., Chang, T.-Y., Lan, Y.-H., Lu, T.-L., Lee, H.-Z., Juang, S.-H., Chen, L.-M., Hsieh, C.-J., Huang, S.-P.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 304 KB

english, 2011

25

Phase I Clinical Study of Seneca Valley Virus (SVV-001),a Replication-Competent Picornavirus, in Advanced Solid Tumors with Neuroendocrine Features

Rudin, C. M., Poirier, J. T., Senzer, N. N., Stephenson, J., Loesch, D., Burroughs, K. D., Reddy, P. S., Hann, C. L., Hallenbeck, P. L.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 786 KB

english, 2011

26

Exploratory Analysis of Early Toxicity of Sunitinib in Advanced Hepatocellular Carcinoma Patients: Kinetics and Potential Biomarker Value

Zhu, A. X., Duda, D. G., Ancukiewicz, M., di Tomaso, E., Clark, J. W., Miksad, R., Fuchs, C. S., Ryan, D. P., Jain, R. K.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 641 KB

english, 2011

27

MEK-Independent Survival of B-RAFV600E Melanoma Cells Selected for Resistance to Apoptosis Induced by the RAF Inhibitor PLX4720

Jiang, C. C., Lai, F., Thorne, R. F., Yang, F., Liu, H., Hersey, P., Zhang, X. D.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 869 KB

english, 2011

28

Frequency of Circulating Tregs with Demethylated FOXP3 Intron 1 in Melanoma Patients Receiving Tumor Vaccines and Potentially Treg-Depleting Agents

de Vries, I. J. M., Castelli, C., Huygens, C., Jacobs, J. F. M., Stockis, J., Schuler-Thurner, B., Adema, G. J., Punt, C. J. A., Rivoltini, L., Schuler, G., Coulie, P. G., Lucas, S.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 400 KB

english, 2011

29

One Allele's Loss Is Another's Gain: Alterations of NKX2-8 in Non-Small Cell Lung Cancer

Neal, J. W., Shaw, A. T.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 256 KB

english, 2011

30

Dasatinib Plus Nutlin-3 Shows Synergistic Antileukemic Activity in Both p53wild-type and p53mutated B Chronic Lymphocytic Leukemias by Inhibiting the Akt Pathway

Zauli, G., Voltan, R., Bosco, R., Melloni, E., Marmiroli, S., Rigolin, G. M., Cuneo, A., Secchiero, P.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 748 KB

english, 2011

31

CYP24A1 Is an Independent Prognostic Marker of Survival in Patients with Lung Adenocarcinoma

Chen, G., Kim, S. H., King, A. N., Zhao, L., Simpson, R. U., Christensen, P. J., Wang, Z., Thomas, D. G., Giordano, T. J., Lin, L., Brenner, D. E., Beer, D. G., Ramnath, N.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 568 KB

english, 2011

32

Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of ENMD-2076, a Novel Angiogenic and Aurora Kinase Inhibitor,in Patients with Advanced Solid Tumors

Diamond, J. R., Bastos, B. R., Hansen, R. J., Gustafson, D. L., Eckhardt, S. G., Kwak, E. L., Pandya, S. S., Fletcher, G. C., Pitts, T. M., Kulikowski, G. N., Morrow, M., Arnott, J., Bray, M. R., Sido

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 775 KB

english, 2011

33

Silibinin Prevents Lung Tumorigenesis in Wild-Type but not in iNOS-/- Mice: Potential of Real-Time Micro-CT in Lung Cancer Chemoprevention Studies

Ramasamy, K., Dwyer-Nield, L. D., Serkova, N. J., Hasebroock, K. M., Tyagi, A., Raina, K., Singh, R. P., Malkinson, A. M., Agarwal, R.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 1.24 MB

english, 2011

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