Volume 18; Issue 2

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Clinical Cancer Research
Volume 18; Issue 2

Clinical Cancer Research

Volume 18; Issue 2

1

Multiple Myeloma Mesenchymal Stem Cells: Characterization, Origin, and Tumor-Promoting Effects

Reagan, M. R., Ghobrial, I. M.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 800 KB

english, 2012

2

EpCAM/CD3-Bispecific T-cell Engaging Antibody MT110 Eliminates Primary Human Pancreatic Cancer Stem Cells

Cioffi, M., Dorado, J., Baeuerle, P. A., Heeschen, C.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.43 MB

english, 2012

3

Molecular Pathways: Osteoclast-Dependent and Osteoclast-Independent Roles of the RANKL/RANK/OPG Pathway in Tumorigenesis and Metastasis

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 4.10 MB

english, 2012

4

Loss of 18q22.3 Involving the Carboxypeptidase of Glutamate-like Gene Is Associated with Poor Prognosis in Resected Pancreatic Cancer

Lee, J.-H., Giovannetti, E., Hwang, J.-H., Petrini, I., Wang, Q., Voortman, J., Wang, Y., Steinberg, S. M., Funel, N., Meltzer, P. S.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

5

Targeting Tumor-Associated Endothelial Cells: Anti-VEGFR2 Immunoliposomes Mediate Tumor Vessel Disruption and Inhibit Tumor Growth

Wicki, A., Rochlitz, C., Orleth, A., Ritschard, R., Albrecht, I., Herrmann, R., Christofori, G., Mamot, C.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 5.80 MB

english, 2012

6

Leflunomide Induces Apoptosis in Fludarabine-Resistant and Clinically Refractory CLL Cells

Dietrich, S., Kramer, O. H., Hahn, E., Schafer, C., Giese, T., Hess, M., Tretter, T., Rieger, M., Hullein, J., Zenz, T., Ho, A. D., Dreger, P., Luft, T.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.77 MB

english, 2012

7

VTX-2337 Is a Novel TLR8 Agonist That Activates NK Cells and Augments ADCC

Lu, H., Dietsch, G. N., Matthews, M.-A. H., Yang, Y., Ghanekar, S., Inokuma, M., Suni, M., Maino, V. C., Henderson, K. E., Howbert, J. J., Disis, M. L., Hershberg, R. M.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 576 KB

english, 2012

8

Association of HER2/ErbB2 Expression and Gene Amplification with Pathologic Features and Prognosis in Esophageal Adenocarcinomas

Yoon, H. H., Shi, Q., Sukov, W. R., Wiktor, A. E., Khan, M., Sattler, C. A., Grothey, A., Wu, T.-T., Diasio, R. B., Jenkins, R. B., Sinicrope, F. A.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 335 KB

english, 2012

9

Anti-EGFR Antibody Cetuximab Enhances the Cytolytic Activity of Natural Killer Cells toward Osteosarcoma

Pahl, J. H. W., Ruslan, S. E. N., Buddingh, E. P., Santos, S. J., Szuhai, K., Serra, M., Gelderblom, H., Hogendoorn, P. C. W., Egeler, R. M., Schilham, M. W., Lankester, A. C.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 728 KB

english, 2012

10

Serum Interleukin-6, Insulin, and HOMA-IR in Male Individuals with Colorectal Adenoma

Sasaki, Y., Takeda, H., Sato, T., Orii, T., Nishise, S., Nagino, K., Iwano, D., Yaoita, T., Yoshizawa, K., Saito, H., Tanaka, Y., Kawata, S.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 426 KB

english, 2012

11

Genetic Variations in Epigenetic Genes Are Predictors of Recurrence in Stage I or II Non-Small Cell Lung Cancer Patients

Wagner, K. W., Ye, Y., Lin, J., Vaporciyan, A. A., Roth, J. A., Wu, X.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 280 KB

english, 2012

12

A Genome-Wide Association Study of Overall Survival in Pancreatic Cancer Patients Treated with Gemcitabine in CALGB 80303

Innocenti, F., Owzar, K., Cox, N. L., Evans, P., Kubo, M., Zembutsu, H., Jiang, C., Hollis, D., Mushiroda, T., Li, L., Friedman, P., Wang, L., Glubb, D., Hurwitz, H., Giacomini, K. M., McLeod, H. L.,

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 445 KB

english, 2012

13

Molecular Analysis of Colorectal Tumors within a Diverse Patient Cohort at a Single Institution

Sylvester, B. E., Huo, D., Khramtsov, A., Zhang, J., Smalling, R. V., Olugbile, S., Polite, B. N., Olopade, O. I.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 435 KB

english, 2012

14

Phase II, Open-Label, Randomized Trial of the MEK1/2 Inhibitor Selumetinib as Monotherapy versus Temozolomide in Patients with Advanced Melanoma

Kirkwood, J. M., Bastholt, L., Robert, C., Sosman, J., Larkin, J., Hersey, P., Middleton, M., Cantarini, M., Zazulina, V., Kemsley, K., Dummer, R.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 374 KB

english, 2012

15

CPTH6, a Thiazole Derivative, Induces Histone Hypoacetylation and Apoptosis in Human Leukemia Cells

Trisciuoglio, D., Ragazzoni, Y., Pelosi, A., Desideri, M., Carradori, S., Gabellini, C., Maresca, G., Nescatelli, R., Secci, D., Bolasco, A., Bizzarri, B., Cavaliere, C., D'Agnano, I., Filetici, P., R

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.92 MB

english, 2012

16

Phase I, Dose-Escalation Trial of the Oral Cyclin-Dependent Kinase 4/6 Inhibitor PD 0332991, Administered Using a 21-Day Schedule in Patients with Advanced Cancer

Flaherty, K. T., LoRusso, P. M., DeMichele, A., Abramson, V. G., Courtney, R., Randolph, S. S., Shaik, M. N., Wilner, K. D., O'Dwyer, P. J., Schwartz, G. K.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 205 KB

english, 2012

17

Iniparib Nonselectively Modifies Cysteine-Containing Proteins in Tumor Cells and Is Not a Bona Fide PARP Inhibitor

Liu, X., Shi, Y., Maag, D. X., Palma, J. P., Patterson, M. J., Ellis, P. A., Surber, B. W., Ready, D. B., Soni, N. B., Ladror, U. S., Xu, A. J., Iyer, R., Harlan, J. E., Solomon, L. R., Donawho, C. K.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 657 KB

english, 2012

18

Lifetime Cancer Risks in Individuals with Germline PTEN Mutations

Tan, M.-H., Mester, J. L., Ngeow, J., Rybicki, L. A., Orloff, M. S., Eng, C.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 633 KB

english, 2012

19

A Noncanonical Flt3ITD/NF- B Signaling Pathway Represses DAPK1 in Acute Myeloid Leukemia

Shanmugam, R., Gade, P., Wilson-Weekes, A., Sayar, H., Suvannasankha, A., Goswami, C., Li, L., Gupta, S., Cardoso, A. A., Al Baghdadi, T., Sargent, K. J., Cripe, L. D., Kalvakolanu, D. V., Boswell, H.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 952 KB

english, 2012

20

Tipping the Noxa/Mcl-1 Balance Overcomes ABT-737 Resistance in Chronic Lymphocytic Leukemia

Tromp, J. M., Geest, C. R., Breij, E. C. W., Elias, J. A., van Laar, J., Luijks, D. M., Kater, A. P., Beaumont, T., van Oers, M. H. J., Eldering, E.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.37 MB

english, 2012

21

New Challenges in Endpoints for Drug Development in Advanced Melanoma

Ribas, A., Hersey, P., Middleton, M. R., Gogas, H., Flaherty, K. T., Sondak, V. K., Kirkwood, J. M.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 217 KB

english, 2012

22

MicroRNA Molecular Profiles Associated with Diagnosis, Clinicopathologic Criteria, and Overall Survival in Patients with Resectable Pancreatic Ductal Adenocarcinoma

Jamieson, N. B., Morran, D. C., Morton, J. P., Ali, A., Dickson, E. J., Carter, C. R., Sansom, O. J., Evans, T. R. J., McKay, C. J., Oien, K. A.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 646 KB

english, 2012

23

Punctate LC3B Expression Is a Common Feature of Solid Tumors and Associated with Proliferation, Metastasis, and Poor Outcome

Lazova, R., Camp, R. L., Klump, V., Siddiqui, S. F., Amaravadi, R. K., Pawelek, J. M.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.92 MB

english, 2012

24

Ran Is a Potential Therapeutic Target for Cancer Cells with Molecular Changes Associated with Activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK Pathways

Yuen, H.-F., Chan, K.-K., Grills, C., Murray, J. T., Platt-Higgins, A., Eldin, O. S., O'Byrne, K., Janne, P., Fennell, D. A., Johnston, P. G., Rudland, P. S., El-Tanani, M.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 2.85 MB

english, 2012

25

Bexarotene via CBP/p300 Induces Suppression of NF- B-Dependent Cell Growth and Invasion in Thyroid Cancer

Cras, A., Politis, B., Balitrand, N., Darsin-Bettinger, D., Boelle, P. Y., Cassinat, B., Toubert, M.-E., Chomienne, C.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 753 KB

english, 2012

26

BAP1tism of a Tumor Suppressor

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 860 KB

english, 2012