Volume 20; Issue 17

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Clinical Cancer Research
Volume 20; Issue 17

Clinical Cancer Research

Volume 20; Issue 17

1

An Integrative Analysis of the Tumorigenic Role of TAZ in Human Non-Small Cell Lung Cancer

Noguchi, S., Saito, A., Horie, M., Mikami, Y., Suzuki, H. I., Morishita, Y., Ohshima, M., Abiko, Y., Mattsson, J. S. M., Konig, H., Lohr, M., Edlund, K., Botling, J., Micke, P., Nagase, T.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.57 MB

english, 2014

2

Decreased Expression of miR216a Contributes to Non-Small-Cell Lung Cancer Progression

Wang, R.-T., Xu, M., Xu, C.-X., Song, Z.-G., Jin, H.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 922 KB

english, 2014

3

Noninvasive Diagnosis of Actionable Mutations by Deep Sequencing of Circulating Free DNA in Lung Cancer from Never-Smokers: A Proof-of-Concept Study from BioCAST/IFCT-1002

Couraud, S., Vaca-Paniagua, F., Villar, S., Oliver, J., Schuster, T., Blanche, H., Girard, N., Tredaniel, J., Guilleminault, L., Gervais, R., Prim, N., Vincent, M., Margery, J., Larive, S., Foucher, P

Journal:

Clinical Cancer Research

Year:

2014

File:

PDF, 315 KB

2014

4

Large-Scale Characterization of DNA Methylation Changes in Human Gastric Carcinomas with and without Metastasis

Liu, Z., Zhang, J., Gao, Y., Pei, L., Zhou, J., Gu, L., Zhang, L., Zhu, B., Hattori, N., Ji, J., Yuasa, Y., Kim, W., Ushijima, T., Shi, H., Deng, D.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 9.64 MB

english, 2014

5

FDA Approval: Ado-Trastuzumab Emtansine for the Treatment of Patients with HER2-Positive Metastatic Breast Cancer

Amiri-Kordestani, L., Blumenthal, G. M., Xu, Q. C., Zhang, L., Tang, S. W., Ha, L., Weinberg, W. C., Chi, B., Candau-Chacon, R., Hughes, P., Russell, A. M., Miksinski, S. P., Chen, X. H., McGuinn, W.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 262 KB

english, 2014

6

To "Grow" or "Go": TMEM16A Expression as a Switch between Tumor Growth and Metastasis in SCCHN

Shiwarski, D. J., Shao, C., Bill, A., Kim, J., Xiao, D., Bertrand, C. A., Seethala, R. S., Sano, D., Myers, J. N., Ha, P., Grandis, J., Gaither, L. A., Puthenveedu, M. A., Duvvuri, U.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 3.64 MB

english, 2014

7

Phase I Safety and Pharmacodynamic of Inecalcitol, a Novel VDR Agonist with Docetaxel in Metastatic Castration-Resistant Prostate Cancer Patients

Medioni, J., Deplanque, G., Ferrero, J.-M., Maurina, T., Rodier, J.-M. P., Raymond, E., Allyon, J., Maruani, G., Houillier, P., Mackenzie, S., Renaux, S., Dufour-Lamartinie, J.-F., Elaidi, R., Lerest,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 360 KB

english, 2014

8

p53MVA Therapy in Patients with Refractory Gastrointestinal Malignancies Elevates p53-Specific CD8+ T-cell Responses

Hardwick, N. R., Carroll, M., Kaltcheva, T., Qian, D., Lim, D., Leong, L., Chu, P., Kim, J., Chao, J., Fakih, M., Yen, Y., Espenschied, J., Ellenhorn, J. D. I., Diamond, D. J., Chung, V.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 730 KB

english, 2014

9

Expression of Androgen and Estrogen Signaling Components and Stem Cell Markers to Predict Cancer Progression and Cancer-Specific Survival in Patients with Metastatic Prostate Cancer

Fujimura, T., Takahashi, S., Urano, T., Takayama, K., Sugihara, T., Obinata, D., Yamada, Y., Kumagai, J., Kume, H., Ouchi, Y., Inoue, S., Homma, Y.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.15 MB

english, 2014

10

New Strategies in Personalized Medicine for Solid Tumors: Molecular Markers and Clinical Trial Designs

Jurgensmeier, J. M., Eder, J. P., Herbst, R. S.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 382 KB

english, 2014

11

SAR650984, A Novel Humanized CD38-Targeting Antibody, Demonstrates Potent Antitumor Activity in Models of Multiple Myeloma and Other CD38+ Hematologic Malignancies

Deckert, J., Wetzel, M.-C., Bartle, L. M., Skaletskaya, A., Goldmacher, V. S., Vallee, F., Zhou-Liu, Q., Ferrari, P., Pouzieux, S., Lahoute, C., Dumontet, C., Plesa, A., Chiron, M., Lejeune, P., Chitt

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.77 MB

english, 2014

12

Biomarker Analyses from a Placebo-Controlled Phase II Study Evaluating Erlotinib Onartuzumab in Advanced Non-Small Cell Lung Cancer: MET Expression Levels Are Predictive of Patient Benefit

Koeppen, H., Yu, W., Zha, J., Pandita, A., Penuel, E., Rangell, L., Raja, R., Mohan, S., Patel, R., Desai, R., Fu, L., Do, A., Parab, V., Xia, X., Januario, T., Louie, S. G., Filvaroff, E., Shames, D.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 677 KB

english, 2014

13

Reversible LSD1 Inhibition Interferes with Global EWS/ETS Transcriptional Activity and Impedes Ewing Sarcoma Tumor Growth

Sankar, S., Theisen, E. R., Bearss, J., Mulvihill, T., Hoffman, L. M., Sorna, V., Beckerle, M. C., Sharma, S., Lessnick, S. L.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.66 MB

english, 2014

14

Dose Selection, Pharmacokinetics, and Pharmacodynamics of BRAF Inhibitor Dabrafenib (GSK2118436)

Falchook, G. S., Long, G. V., Kurzrock, R., Kim, K. B., Arkenau, H.- T., Brown, M. P., Hamid, O., Infante, J. R., Millward, M., Pavlick, A., Chin, M. T., O'Day, S. J., Blackman, S. C., Curtis, C. M.,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 759 KB

english, 2014

15

miR-409-3p/-5p Promotes Tumorigenesis, Epithelial-to-Mesenchymal Transition, and Bone Metastasis of Human Prostate Cancer

Josson, S., Gururajan, M., Hu, P., Shao, C., Chu, G. C.-Y., Zhau, H. E., Liu, C., Lao, K., Lu, C.-L., Lu, Y.-T., Lichterman, J., Nandana, S., Li, Q., Rogatko, A., Berel, D., Posadas, E. M., Fazli, L.,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 2.03 MB

english, 2014

16

Detection of Minimal Residual Disease in B Lymphoblastic Leukemia by High-Throughput Sequencing of IGH

Wu, D., Emerson, R. O., Sherwood, A., Loh, M. L., Angiolillo, A., Howie, B., Vogt, J., Rieder, M., Kirsch, I., Carlson, C., Williamson, D., Wood, B. L., Robins, H.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.93 MB

english, 2014

17

A let-7 microRNA-Binding Site Polymorphism in KRAS Predicts Improved Outcome in Patients with Metastatic Colorectal Cancer Treated with Salvage Cetuximab/Panitumumab Monotherapy

Saridaki, Z., Weidhaas, J. B., Lenz, H.-J., Laurent-Puig, P., Jacobs, B., De Schutter, J., De Roock, W., Salzman, D. W., Zhang, W., Yang, D., Pilati, C., Bouche, O., Piessevaux, H., Tejpar, S.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 806 KB

english, 2014

18

Noninvasive Detection of Glutamate Predicts Survival in Pediatric Medulloblastoma

Wilson, M., Gill, S. K., MacPherson, L., English, M., Arvanitis, T. N., Peet, A. C.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 444 KB

english, 2014

19

Association of EGFR Expression Level and Cetuximab Activity in Patient-Derived Xenograft Models of Human Non-Small Cell Lung Cancer

Amendt, C., Staub, E., Friese-Hamim, M., Storkel, S., Stroh, C.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 760 KB

english, 2014

20

Functional Genetic Approach Identifies MET, HER3, IGF1R, INSR Pathways as Determinants of Lapatinib Unresponsiveness in HER2-Positive Gastric Cancer

Zhang, Z., Wang, J., Ji, D., Wang, C., Liu, R., Wu, Z., Liu, L., Zhu, D., Chang, J., Geng, R., Xiong, L., Fang, Q., Li, J.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 2.43 MB

english, 2014

21

Molecular Pathways: Targeting ETS Gene Fusions in Cancer

Feng, F. Y., Brenner, J. C., Hussain, M., Chinnaiyan, A. M.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 474 KB

english, 2014

22

TMEFF2 Deregulation Contributes to Gastric Carcinogenesis and Indicates Poor Survival Outcome

Sun, T., Du, W., Xiong, H., Yu, Y., Weng, Y., Ren, L., Zhao, H., Wang, Y., Chen, Y., Xu, J., Xiang, Y., Qin, W., Cao, W., Zou, W., Chen, H., Hong, J., Fang, J.-Y.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 2.50 MB

english, 2014

23

GSK-3 -Regulated N-Acetyltransferase 10 Is Involved in Colorectal Cancer Invasion

Zhang, H., Hou, W., Wang, H.-L., Liu, H.-J., Jia, X.-Y., Zheng, X.-Z., Zou, Y.-X., Li, X., Hou, L., McNutt, M. A., Zhang, B.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 2.89 MB

english, 2014

24

Cell and Molecular Determinants of In Vivo Efficacy of the BH3 Mimetic ABT-263 against Pediatric Acute Lymphoblastic Leukemia Xenografts

Suryani, S., Carol, H., Chonghaile, T. N., Frismantas, V., Sarmah, C., High, L., Bornhauser, B., Cowley, M. J., Szymanska, B., Evans, K., Boehm, I., Tonna, E., Jones, L., Manesh, D. M., Kurmasheva, R.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.72 MB

english, 2014

25

TP53 Mutations and Lung Cancer: Not All Mutations Are Created Equal

Govindan, R., Weber, J.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 337 KB

english, 2014

26

"Companion Diagnostics": Has Their Time Come and Gone?

Hirsch, F. R., Bunn, P. A., Herbst, R. S.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 203 KB

english, 2014

27

Nondisruptive p53 Mutations Are Associated with Shorter Survival in Patients with Advanced Non-Small Cell Lung Cancer

Molina-Vila, M. A., Bertran-Alamillo, J., Gasco, A., Mayo-de-las-Casas, C., Sanchez-Ronco, M., Pujantell-Pastor, L., Bonanno, L., Favaretto, A. G., Cardona, A. F., Vergnenegre, A., Majem, M., Massuti,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 618 KB

english, 2014

28

Fc RIIa and Fc RIIIa Polymorphisms and Cetuximab Benefit in the Microscopic Disease

Sclafani, F., Gonzalez de Castro, D., Cunningham, D., Hulkki Wilson, S., Peckitt, C., Capdevila, J., Glimelius, B., Rosello Keranen, S., Wotherspoon, A., Brown, G., Tait, D., Begum, R., Thomas, J., Oa

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 247 KB

english, 2014

29

The Combination of Circulating Ang1 and Tie2 Levels Predicts Progression-Free Survival Advantage in Bevacizumab-Treated Patients with Ovarian Cancer

Backen, A., Renehan, A. G., Clamp, A. R., Berzuini, C., Zhou, C., Oza, A., Bannoo, S., Scherer, S. J., Banks, R. E., Dive, C., Jayson, G. C.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 377 KB

english, 2014