Volume 20; Issue 22

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Clinical Cancer Research
Volume 20; Issue 22

Clinical Cancer Research

Volume 20; Issue 22

1

Two Novel ALK Mutations Mediate Acquired Resistance to the Next-Generation ALK Inhibitor Alectinib

Katayama, R., Friboulet, L., Koike, S., Lockerman, E. L., Khan, T. M., Gainor, J. F., Iafrate, A. J., Takeuchi, K., Taiji, M., Okuno, Y., Fujita, N., Engelman, J. A., Shaw, A. T.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.70 MB

english, 2014

2

Neuroblastoma Killing Properties of V 2 and V 2-Negative T Cells Following Expansion by Artificial Antigen-Presenting Cells

Fisher, J. P. H., Yan, M., Heuijerjans, J., Carter, L., Abolhassani, A., Frosch, J., Wallace, R., Flutter, B., Capsomidis, A., Hubank, M., Klein, N., Callard, R., Gustafsson, K., Anderson, J.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 2.02 MB

english, 2014

3

Activating and Propagating Polyclonal Gamma Delta T Cells with Broad Specificity for Malignancies

Deniger, D. C., Maiti, S. N., Mi, T., Switzer, K. C., Ramachandran, V., Hurton, L. V., Ang, S., Olivares, S., Rabinovich, B. A., Huls, M. H., Lee, D. A., Bast, R. C., Champlin, R. E., Cooper, L. J. N.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 4.20 MB

english, 2014

4

The Renin-Angiotensin System Mediates EGF Receptor-Vitamin D Receptor Cross-Talk in Colitis-Associated Colon Cancer

Dougherty, U., Mustafi, R., Sadiq, F., Almoghrabi, A., Mustafi, D., Kreisheh, M., Sundaramurthy, S., Liu, W., Konda, V. J., Pekow, J., Khare, S., Hart, J., Joseph, L., Wyrwicz, A., Karczmar, G. S., Li

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 19.00 MB

english, 2014

5

Validation of Biomarkers That Complement CA19.9 in Detecting Early Pancreatic Cancer

Chan, A., Prassas, I., Dimitromanolakis, A., Brand, R. E., Serra, S., Diamandis, E. P., Blasutig, I. M.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 902 KB

english, 2014

6

Immunotherapy for Primary Brain Tumors: No Longer a Matter of Privilege

Fecci, P. E., Heimberger, A. B., Sampson, J. H.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 705 KB

english, 2014

7

Facing the Future of Brain Tumor Clinical Research

Gilbert, M. R., Armstrong, T. S., Pope, W. B., van den Bent, M. J., Wen, P. Y.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 528 KB

english, 2014

8

Promising Cell-Based Immunotherapy Using Gamma Delta T Cells: Together Is Better

Dechanet-Merville, J.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 327 KB

english, 2014

9

The Evolving Role of Molecular Markers in the Diagnosis and Management of Diffuse Glioma

Huse, J. T., Aldape, K. D.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 932 KB

english, 2014

10

Tumor-Suppressive miR148a Is Silenced by CpG Island Hypermethylation in IDH1-Mutant Gliomas

Li, S., Chowdhury, R., Liu, F., Chou, A. P., Li, T., Mody, R. R., Lou, J. J., Chen, W., Reiss, J., Soto, H., Prins, R., Liau, L. M., Mischel, P. S., Nghiemphu, P. L., Yong, W. H., Cloughesy, T. F., La

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

11

PIK3CA Mutational Status in Circulating Tumor Cells Can Change During Disease Recurrence or Progression in Patients with Breast Cancer

Markou, A., Farkona, S., Schiza, C., Efstathiou, T., Kounelis, S., Malamos, N., Georgoulias, V., Lianidou, E.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 999 KB

english, 2014

12

Phase II Study of Perifosine and Sorafenib Dual-Targeted Therapy in Patients with Relapsed or Refractory Lymphoproliferative Diseases

Guidetti, A., Carlo-Stella, C., Locatelli, S. L., Malorni, W., Mortarini, R., Viviani, S., Russo, D., Marchiano, A., Sorasio, R., Dodero, A., Farina, L., Giordano, L., Di Nicola, M., Anichini, A., Cor

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 491 KB

english, 2014

13

Dual mTORC1/2 Blockade Inhibits Glioblastoma Brain Tumor Initiating Cells In Vitro and In Vivo and Synergizes with Temozolomide to Increase Orthotopic Xenograft Survival

Luchman, H. A., Stechishin, O. D. M., Nguyen, S. A., Lun, X. Q., Cairncross, J. G., Weiss, S.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.79 MB

english, 2014

14

Antiangiogenic Therapy for Glioblastoma: Current Status and Future Prospects

Batchelor, T. T., Reardon, D. A., de Groot, J. F., Wick, W., Weller, M.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 577 KB

english, 2014

15

Interrogating Two Schedules of the AKT Inhibitor MK-2206 in Patients with Advanced Solid Tumors Incorporating Novel Pharmacodynamic and Functional Imaging Biomarkers

Yap, T. A., Yan, L., Patnaik, A., Tunariu, N., Biondo, A., Fearen, I., Papadopoulos, K. P., Olmos, D., Baird, R., Delgado, L., Tetteh, E., Beckman, R. A., Lupinacci, L., Riisnaes, R., Decordova, S., H

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 693 KB

english, 2014

16

Molecular Insights into Pediatric Brain Tumors Have the Potential to Transform Therapy

Gajjar, A., Pfister, S. M., Taylor, M. D., Gilbertson, R. J.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 826 KB

english, 2014

17

Lung Squamous Cell Carcinomas with Basaloid Histology Represent a Specific Molecular Entity

Brambilla, C., Laffaire, J., Lantuejoul, S., Moro-Sibilot, D., Mignotte, H., Arbib, F., Toffart, A.-C., Petel, F., Hainaut, P., Rousseaux, S., Khochbin, S., de Reynies, A., Brambilla, E.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.52 MB

english, 2014

18

Perfect ALKemy: Optimizing the Use of ALK-Directed Therapies in Lung Cancer

Politi, K., Gettinger, S.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 345 KB

english, 2014

19

Ponatinib Inhibits Polyclonal Drug-Resistant KIT Oncoproteins and Shows Therapeutic Potential in Heavily Pretreated Gastrointestinal Stromal Tumor (GIST) Patients

Garner, A. P., Gozgit, J. M., Anjum, R., Vodala, S., Schrock, A., Zhou, T., Serrano, C., Eilers, G., Zhu, M., Ketzer, J., Wardwell, S., Ning, Y., Song, Y., Kohlmann, A., Wang, F., Clackson, T., Heinri

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 974 KB

english, 2014

20

Dose-Response Relationship in Phase I Clinical Trials: A European Drug Development Network (EDDN) Collaboration Study

Moreno Garcia, V., Olmos, D., Gomez-Roca, C., Cassier, P. A., Morales-Barrera, R., Del Conte, G., Gallerani, E., Brunetto, A. T., Schoffski, P., Marsoni, S., Schellens, J. H. M., Penel, N., Voest, E.,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 509 KB

english, 2014

21

A HGF/cMET Autocrine Loop Is Operative in Multiple Myeloma Bone Marrow Endothelial Cells and May Represent a Novel Therapeutic Target

Ferrucci, A., Moschetta, M., Frassanito, M. A., Berardi, S., Catacchio, I., Ria, R., Racanelli, V., Caivano, A., Solimando, A. G., Vergara, D., Maffia, M., Latorre, D., Rizzello, A., Zito, A., Ditonno

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 2.35 MB

english, 2014

22

Human Anaplastic Thyroid Carcinoma Cells Are Sensitive to NK Cell-Mediated Lysis via ULBP2/5/6 and Chemoattract NK Cells

Wennerberg, E., Pfefferle, A., Ekblad, L., Yoshimoto, Y., Kremer, V., Kaminskyy, V. O., Juhlin, C. C., Hoog, A., Bodin, I., Svjatoha, V., Larsson, C., Zedenius, J., Wennerberg, J., Lundqvist, A.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 743 KB

english, 2014

23

STAT3 Mediates Regorafenib-Induced Apoptosis in Hepatocellular Carcinoma

Tai, W.-T., Chu, P.-Y., Shiau, C.-W., Chen, Y.-L., Li, Y.-S., Hung, M.-H., Chen, L.-J., Chen, P.-L., Su, J.-C., Lin, P.-Y., Yu, H.-C., Chen, K.-F.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.84 MB

english, 2014

24

Central Nervous System Malignancies: What Next?

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 84 KB

english, 2014

25

Molecular Pathways: IL11 as a Tumor-Promoting Cytokine--Translational Implications for Cancers

Ernst, M., Putoczki, T. L.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 955 KB

english, 2014

26

Serum Interleukin-8 Reflects Tumor Burden and Treatment Response across Malignancies of Multiple Tissue Origins

Sanmamed, M. F., Carranza-Rua, O., Alfaro, C., Onate, C., Martin-Algarra, S., Perez, G., Landazuri, S. F., Gonzalez, A., Gross, S., Rodriguez, I., Munoz-Calleja, C., Rodriguez-Ruiz, M., Sangro, B., Lo

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 999 KB

english, 2014

27

LIM and SH3 Protein 1 Induces TGF -Mediated Epithelial-Mesenchymal Transition in Human Colorectal Cancer by Regulating S100A4 Expression

Wang, H., Shi, J., Luo, Y., Liao, Q., Niu, Y., Zhang, F., Shao, Z., Ding, Y., Zhao, L.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 3.62 MB

english, 2014

28

Phase I Trial of Bortezomib (PS-341; NSC 681239) and "Nonhybrid" (Bolus) Infusion Schedule of Alvocidib (Flavopiridol; NSC 649890) in Patients with Recurrent or Refractory Indolent B-cell Neoplasms

Holkova, B., Kmieciak, M., Perkins, E. B., Bose, P., Baz, R. C., Roodman, G. D., Stuart, R. K., Ramakrishnan, V., Wan, W., Peer, C. J., Dawson, J., Kang, L., Honeycutt, C., Tombes, M. B., Shrader, E.,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 457 KB

english, 2014

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