Volume 20; Issue 23

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Clinical Cancer Research
Volume 20; Issue 23

Clinical Cancer Research

Volume 20; Issue 23

1

Therapeutic Strategies Utilized in the Setting of Acquired Resistance to EGFR Tyrosine Kinase Inhibitors

Yu, H. A., Riely, G. J., Lovly, C. M.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 2.94 MB

english, 2014

2

Calreticulin Promotes Migration and Invasion of Esophageal Cancer Cells by Upregulating Neuropilin-1 Expression via STAT5A

Shi, F., Shang, L., Pan, B.-Q., Wang, X.-M., Jiang, Y.-Y., Hao, J.-J., Zhang, Y., Cai, Y., Xu, X., Zhan, Q.-M., Wang, M.-R.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 6.00 MB

english, 2014

3

Ramucirumab: Successfully Targeting Angiogenesis in Gastric Cancer

Javle, M., Smyth, E. C., Chau, I.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

4

Multiplexed Quantitative Analysis of CD3, CD8, and CD20 Predicts Response to Neoadjuvant Chemotherapy in Breast Cancer

Brown, J. R., Wimberly, H., Lannin, D. R., Nixon, C., Rimm, D. L., Bossuyt, V.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.34 MB

english, 2014

5

ABO Blood Group IgM Isoagglutinins Interact with Tumor-Associated O-Glycan Structures in Pancreatic Cancer

Hofmann, B. T., Stehr, A., Dohrmann, T., Gungor, C., Herich, L., Hiller, J., Harder, S., Ewald, F., Gebauer, F., Tachezy, M., Precht, C., Izbicki, J. R., Bockhorn, M., Wagener, C., Wolters-Eisfeld, G.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 826 KB

english, 2014

6

Elevated Serum Angiopoietin-like Protein 2 Correlates with the Metastatic Properties of Colorectal Cancer: A Serum Biomarker for Early Diagnosis and Recurrence

Toiyama, Y., Tanaka, K., Kitajima, T., Shimura, T., Kawamura, M., Kawamoto, A., Okugawa, Y., Saigusa, S., Hiro, J., Inoue, Y., Mohri, Y., Goel, A., Kusunoki, M.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.06 MB

english, 2014

7

Whole-Body Low-Dose Computed Tomography and Advanced Imaging Techniques for Multiple Myeloma Bone Disease

Pianko, M. J., Terpos, E., Roodman, G. D., Divgi, C. R., Zweegman, S., Hillengass, J., Lentzsch, S.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 319 KB

english, 2014

8

MHC Class I Loss Is a Frequent Mechanism of Immune Escape in Papillary Thyroid Cancer That Is Reversed by Interferon and Selumetinib Treatment In Vitro

Angell, T. E., Lechner, M. G., Jang, J. K., LoPresti, J. S., Epstein, A. L.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.63 MB

english, 2014

9

Safety and Preliminary Evidence of Biologic Efficacy of a Mammaglobin-A DNA Vaccine in Patients with Stable Metastatic Breast Cancer

Tiriveedhi, V., Tucker, N., Herndon, J., Li, L., Sturmoski, M., Ellis, M., Ma, C., Naughton, M., Lockhart, A. C., Gao, F., Fleming, T., Goedegebuure, P., Mohanakumar, T., Gillanders, W. E.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

10

Molecular Pathways: Exploiting Tumor-Specific Molecular Defects in DNA Repair Pathways for Precision Cancer Therapy

Dietlein, F., Reinhardt, H. C.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 627 KB

english, 2014

11

Effects of Tumor Microenvironment Heterogeneity on Nanoparticle Disposition and Efficacy in Breast Cancer Tumor Models

Song, G., Darr, D. B., Santos, C. M., Ross, M., Valdivia, A., Jordan, J. L., Midkiff, B. R., Cohen, S., Nikolaishvili-Feinberg, N., Miller, C. R., Tarrant, T. K., Rogers, A. B., Dudley, A. C., Perou,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 2.18 MB

english, 2014

12

AMACR Amplification in Myxofibrosarcomas: A Mechanism of Overexpression That Promotes Cell Proliferation with Therapeutic Relevance

Li, C.-F., Fang, F.-M., Lan, J., Wang, J.-W., Kung, H.-J., Chen, L.-T., Chen, T.-J., Li, S.-H., Wang, Y.-H., Tai, H.-C., Yu, S.-C., Huang, H.-Y.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 3.12 MB

english, 2014

13

p38 MAPK in Pancreatic Cancer: Finding a Protective Needle in the Haystack

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 347 KB

english, 2014

14

Team Work Matters: Dual Inhibition Puts Non-Hodgkin Lymphoma Under Siege

Bianchi, G., Ghobrial, I. M.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 376 KB

english, 2014

15

Efficacy of Anti-RON Antibody Zt/g4-Drug Maytansinoid Conjugation (Anti-RON ADC) as a Novel Therapeutics for Targeted Colorectal Cancer Therapy

Feng, L., Yao, H.-P., Wang, W., Zhou, Y.-Q., Zhou, J., Zhang, R., Wang, M.-H.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 2.16 MB

english, 2014

16

miR-204-5p Inhibits Proliferation and Invasion and Enhances Chemotherapeutic Sensitivity of Colorectal Cancer Cells by Downregulating RAB22A

Yin, Y., Zhang, B., Wang, W., Fei, B., Quan, C., Zhang, J., Song, M., Bian, Z., Wang, Q., Ni, S., Hu, Y., Mao, Y., Zhou, L., Wang, Y., Yu, J., Du, X., Hua, D., Huang, Z.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 3.33 MB

english, 2014

17

New Strategies in Chronic Lymphocytic Leukemia: Shifting Treatment Paradigms

Awan, F. T., Byrd, J. C.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.60 MB

english, 2014

18

A Phase II Study of the Efficacy and Safety of the Combination Therapy of the MEK Inhibitor Refametinib (BAY 86-9766) Plus Sorafenib for Asian Patients with Unresectable Hepatocellular Carcinoma

Lim, H. Y., Heo, J., Choi, H. J., Lin, C.-Y., Yoon, J.-H., Hsu, C., Rau, K.-M., Poon, R. T. P., Yeo, W., Park, J.-W., Tay, M. H., Hsieh, W.-S., Kappeler, C., Rajagopalan, P., Krissel, H., Jeffers, M.,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 284 KB

english, 2014

19

Pilot Clinical Trial of Hedgehog Pathway Inhibitor GDC-0449 (Vismodegib) in Combination with Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma

Kim, E. J., Sahai, V., Abel, E. V., Griffith, K. A., Greenson, J. K., Takebe, N., Khan, G. N., Blau, J. L., Craig, R., Balis, U. G., Zalupski, M. M., Simeone, D. M.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 548 KB

english, 2014

20

Phase II Clinical Trial of Amatuximab, a Chimeric Antimesothelin Antibody with Pemetrexed and Cisplatin in Advanced Unresectable Pleural Mesothelioma

Hassan, R., Kindler, H. L., Jahan, T., Bazhenova, L., Reck, M., Thomas, A., Pastan, I., Parno, J., O'Shannessy, D. J., Fatato, P., Maltzman, J. D., Wallin, B. A.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 416 KB

english, 2014

21

Systemic Immune-Inflammation Index Predicts Prognosis of Patients after Curative Resection for Hepatocellular Carcinoma

Hu, B., Yang, X.-R., Xu, Y., Sun, Y.-F., Sun, C., Guo, W., Zhang, X., Wang, W.-M., Qiu, S.-J., Zhou, J., Fan, J.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.06 MB

english, 2014

22

Plasma Levels of Heat Shock Protein 90 Alpha Associated with Lung Cancer Development and Treatment Responses

Shi, Y., Liu, X., Lou, J., Han, X., Zhang, L., Wang, Q., Li, B., Dong, M., Zhang, Y.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 497 KB

english, 2014

23

Tumor Genotype Is an Independent Prognostic Factor in Primary Gastrointestinal Stromal Tumors of Gastric Origin: A European Multicenter Analysis Based on ConticaGIST

Wozniak, A., Rutkowski, P., Schoffski, P., Ray-Coquard, I., Hostein, I., Schildhaus, H.-U., Le Cesne, A., Bylina, E., Limon, J., Blay, J.-Y., Siedlecki, J. A., Wardelmann, E., Sciot, R., Coindre, J.-M

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 484 KB

english, 2014

24

An Open-Label Phase Ib Dose-Escalation Study of TRC105 (Anti-Endoglin Antibody) with Bevacizumab in Patients with Advanced Cancer

Gordon, M. S., Robert, F., Matei, D., Mendelson, D. S., Goldman, J. W., Chiorean, E. G., Strother, R. M., Seon, B. K., Figg, W. D., Peer, C. J., Alvarez, D., Adams, B. J., Theuer, C. P., Rosen, L. S.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 253 KB

english, 2014

25

T-Cell Levels Are Prognostic in Mantle Cell Lymphoma

Nygren, L., Wasik, A. M., Baumgartner-Wennerholm, S., Jeppsson-Ahlberg, A., Klimkowska, M., Andersson, P., Buhrkuhl, D., Christensson, B., Kimby, E., Wahlin, B. E., Sander, B.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 449 KB

english, 2014

26

LY2875358, a Neutralizing and Internalizing Anti-MET Bivalent Antibody, Inhibits HGF-Dependent and HGF-Independent MET Activation and Tumor Growth

Liu, L., Zeng, W., Wortinger, M. A., Yan, S. B., Cornwell, P., Peek, V. L., Stephens, J. R., Tetreault, J. W., Xia, J., Manro, J. R., Credille, K. M., Ballard, D. W., Brown-Augsburger, P., Wacheck, V.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

27

Correction: Phase I Dose Escalation Study of MEDI-573, a Bispecific, Antiligand Monoclonal Antibody against IGFI and IGFII, in Patients with Advanced Solid Tumors

Journal:

Clinical Cancer Research

Year:

2014

File:

PDF, 96 KB

2014

28

First-in-Human Study of CH5132799, an Oral Class I PI3K Inhibitor, Studying Toxicity, Pharmacokinetics, and Pharmacodynamics, in Patients with Metastatic Cancer

Blagden, S., Olmin, A., Josephs, D., Stavraka, C., Zivi, A., Pinato, D. J., Anthoney, A., Decordova, S., Swales, K., Riisnaes, R., Pope, L., Noguchi, K., Shiokawa, R., Inatani, M., Prince, J., Jones,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 656 KB

english, 2014

29

Thomas C. Hall, MD, FACP: In Memoriam

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 276 KB

english, 2014

30

The Novel Organic Arsenical Darinaparsin Induces MAPK-Mediated and SHP1-Dependent Cell Death in T-cell Lymphoma and Hodgkin Lymphoma Cells and Human Xenograft Models

Ravi, D., Bhalla, S., Gartenhaus, R. B., Crombie, J., Kandela, I., Sharma, J., Mazar, A., Evens, A. M.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.15 MB

english, 2014

31

Synergy Between VEGF/VEGFR Inhibitors and Chemotherapy Agents in the Phase I Clinic

Tang, C., Hess, K., Jardim, D. L. F., Gagliato, D. D. M., Tsimberidou, A. M., Falchook, G., Fu, S., Janku, F., Naing, A., Piha-Paul, S., Subbiah, V., Wheler, J., Zinner, R. G., Kurzrock, R., Ellis, L.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 512 KB

english, 2014

32

A Phase I Trial of Single-Agent Reolysin in Patients with Relapsed Multiple Myeloma

Sborov, D. W., Nuovo, G. J., Stiff, A., Mace, T., Lesinski, G. B., Benson, D. M., Efebera, Y. A., Rosko, A. E., Pichiorri, F., Grever, M. R., Hofmeister, C. C.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 777 KB

english, 2014

33

Complement Pathway Is Frequently Altered in Endometriosis and Endometriosis-Associated Ovarian Cancer

Suryawanshi, S., Huang, X., Elishaev, E., Budiu, R. A., Zhang, L., Kim, S., Donnellan, N., Mantia-Smaldone, G., Ma, T., Tseng, G., Lee, T., Mansuria, S., Edwards, R. P., Vlad, A. M.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 2.10 MB

english, 2014

34

Phosphoinositide 3-Kinase Inhibitors Combined with Imatinib in Patient-Derived Xenograft Models of Gastrointestinal Stromal Tumors: Rationale and Efficacy

Van Looy, T., Wozniak, A., Floris, G., Sciot, R., Li, H., Wellens, J., Vanleeuw, U., Fletcher, J. A., Manley, P. W., Debiec-Rychter, M., Schoffski, P.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 637 KB

english, 2014

35

Predicting Breast Tumor Response to Neoadjuvant Chemotherapy with Diffuse Optical Spectroscopic Tomography prior to Treatment

Jiang, S., Pogue, B. W., Kaufman, P. A., Gui, J., Jermyn, M., Frazee, T. E., Poplack, S. P., DiFlorio-Alexander, R., Wells, W. A., Paulsen, K. D.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 892 KB

english, 2014

36

Genome-wide DNA Methylation Analysis of Lung Carcinoma Reveals One Neuroendocrine and Four Adenocarcinoma Epitypes Associated with Patient Outcome

Karlsson, A., Jonsson, M., Lauss, M., Brunnstrom, H., Jonsson, P., Borg, A., Jonsson, G., Ringner, M., Planck, M., Staaf, J.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 925 KB

english, 2014

37

Functional p38 MAPK Identified by Biomarker Profiling of Pancreatic Cancer Restrains Growth through JNK Inhibition and Correlates with Improved Survival

Zhong, Y., Naito, Y., Cope, L., Naranjo-Suarez, S., Saunders, T., Hong, S.-M., Goggins, M. G., Herman, J. M., Wolfgang, C. L., Iacobuzio-Donahue, C. A.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.62 MB

english, 2014

38

NK Cell Genotype and Phenotype at Diagnosis of Acute Lymphoblastic Leukemia Correlate with Postinduction Residual Disease

Sullivan, E. M., Jeha, S., Kang, G., Cheng, C., Rooney, B., Holladay, M., Bari, R., Schell, S., Tuggle, M., Pui, C.-H., Leung, W.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 470 KB

english, 2014