Volume 20; Issue 7

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Clinical Cancer Research
Volume 20; Issue 7

Clinical Cancer Research

Volume 20; Issue 7

1

The Impact of EGFR T790M Mutations and BIM mRNA Expression on Outcome in Patients with EGFR-Mutant NSCLC Treated with Erlotinib or Chemotherapy in the Randomized Phase III EURTAC Trial

Costa, C., Molina, M. A., Drozdowskyj, A., Gimenez-Capitan, A., Bertran-Alamillo, J., Karachaliou, N., Gervais, R., Massuti, B., Wei, J., Moran, T., Majem, M., Felip, E., Carcereny, E., Garcia-Campelo

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 651 KB

english, 2014

2

A Short Treatment with Galactomannan GM-CT-01 Corrects the Functions of Freshly Isolated Human Tumor-Infiltrating Lymphocytes

Demotte, N., Bigirimana, R., Wieers, G., Stroobant, V., Squifflet, J.-L., Carrasco, J., Thielemans, K., Baurain, J.-F., Van Der Smissen, P., Courtoy, P. J., van der Bruggen, P.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 966 KB

english, 2014

3

Emergence of Constitutively Active Estrogen Receptor- Mutations in Pretreated Advanced Estrogen Receptor-Positive Breast Cancer

Jeselsohn, R., Yelensky, R., Buchwalter, G., Frampton, G., Meric-Bernstam, F., Gonzalez-Angulo, A. M., Ferrer-Lozano, J., Perez-Fidalgo, J. A., Cristofanilli, M., Gomez, H., Arteaga, C. L., Giltnane,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 805 KB

english, 2014

4

Intratumoral Immunization: A New Paradigm for Cancer Therapy

Marabelle, A., Kohrt, H., Caux, C., Levy, R.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 444 KB

english, 2014

5

Estrogen Receptor Mutations in Breast Cancer--New Focus on an Old Target

Segal, C. V., Dowsett, M.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 350 KB

english, 2014

6

BRAF Inhibitor Resistance Mechanisms in Metastatic Melanoma: Spectrum and Clinical Impact

Rizos, H., Menzies, A. M., Pupo, G. M., Carlino, M. S., Fung, C., Hyman, J., Haydu, L. E., Mijatov, B., Becker, T. M., Boyd, S. C., Howle, J., Saw, R., Thompson, J. F., Kefford, R. F., Scolyer, R. A.,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.01 MB

english, 2014

7

Circulating Oncometabolite 2-Hydroxyglutarate Is a Potential Surrogate Biomarker in Patients with Isocitrate Dehydrogenase-Mutant Intrahepatic Cholangiocarcinoma

Borger, D. R., Goyal, L., Yau, T., Poon, R. T., Ancukiewicz, M., Deshpande, V., Christiani, D. C., Liebman, H. M., Yang, H., Kim, H., Yen, K., Faris, J. E., Iafrate, A. J., Kwak, E. L., Clark, J. W.,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 629 KB

english, 2014

8

Reduced Expression of miRNA-27a Modulates Cisplatin Resistance in Bladder Cancer by Targeting the Cystine/Glutamate Exchanger SLC7A11

Drayton, R. M., Dudziec, E., Peter, S., Bertz, S., Hartmann, A., Bryant, H. E., Catto, J. W.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 999 KB

english, 2014

9

A Panel of Three Markers Hyper- and Hypomethylated in Urine Sediments Accurately Predicts Bladder Cancer Recurrence

Su, S.-F., de Castro Abreu, A. L., Chihara, Y., Tsai, Y., Andreu-Vieyra, C., Daneshmand, S., Skinner, E. C., Jones, P. A., Siegmund, K. D., Liang, G.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

10

Functional Identification of Cancer-Specific Methylation of CDO1, HOXA9, and TAC1 for the Diagnosis of Lung Cancer

Wrangle, J., Machida, E. O., Danilova, L., Hulbert, A., Franco, N., Zhang, W., Glockner, S. C., Tessema, M., Van Neste, L., Easwaran, H., Schuebel, K. E., Licchesi, J., Hooker, C. M., Ahuja, N., Amano

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.02 MB

english, 2014

11

Molecular Pathways: Emerging Roles of Mammalian Sirtuin SIRT7 in Cancer

Paredes, S., Villanova, L., Chua, K. F.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 440 KB

english, 2014

12

Omacetaxine: A Protein Translation Inhibitor for Treatment of Chronic Myelogenous Leukemia

Gandhi, V., Plunkett, W., Cortes, J. E.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 374 KB

english, 2014

13

Prognostic and Predictive Values of the Immunoscore in Patients with Rectal Cancer

Anitei, M.-G., Zeitoun, G., Mlecnik, B., Marliot, F., Haicheur, N., Todosi, A.-M., Kirilovsky, A., Lagorce, C., Bindea, G., Ferariu, D., Danciu, M., Bruneval, P., Scripcariu, V., Chevallier, J.-M., Zi

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 738 KB

english, 2014

14

Phase Ib Study of Buparlisib plus Trastuzumab in Patients with HER2-Positive Advanced or Metastatic Breast Cancer That Has Progressed on Trastuzumab-Based Therapy

Saura, C., Bendell, J., Jerusalem, G., Su, S., Ru, Q., De Buck, S., Mills, D., Ruquet, S., Bosch, A., Urruticoechea, A., Beck, J. T., Di Tomaso, E., Sternberg, D. W., Massacesi, C., Hirawat, S., Dirix

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 898 KB

english, 2014

15

Definition of Primary and Secondary Glioblastoma--Response

Ohgaki, H., Burger, P., Kleihues, P.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 414 KB

english, 2014

16

Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers

Garcia, P. D., Langowski, J. L., Wang, Y., Chen, M., Castillo, J., Fanton, C., Ison, M., Zavorotinskaya, T., Dai, Y., Lu, J., Niu, X.-H., Basham, S., Chan, J., Yu, J., Doyle, M., Feucht, P., Warne, R.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.03 MB

english, 2014

17

Definition of Primary and Secondary Glioblastoma--Letter

Werner, P., Fritzsch, D., Holland, H., Bauer, M., Krupp, W., Hoffmann, K.-T., Saur, D., Then Bergh, F., Sabri, O., Barthel, H.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 393 KB

english, 2014

18

Topical Application of a Mucoadhesive Freeze-Dried Black Raspberry Gel Induces Clinical and Histologic Regression and Reduces Loss of Heterozygosity Events in Premalignant Oral Intraepithelial Lesions: Results from a Multicentered, Placebo-Controlled Clinical Trial

Mallery, S. R., Tong, M., Shumway, B. S., Curran, A. E., Larsen, P. E., Ness, G. M., Kennedy, K. S., Blakey, G. H., Kushner, G. M., Vickers, A. M., Han, B., Pei, P., Stoner, G. D.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.81 MB

english, 2014

19

Integrative Analysis of 1q23.3 Copy-Number Gain in Metastatic Urothelial Carcinoma

Riester, M., Werner, L., Bellmunt, J., Selvarajah, S., Guancial, E. A., Weir, B. A., Stack, E. C., Park, R. S., O'Brien, R., Schutz, F. A. B., Choueiri, T. K., Signoretti, S., Lloreta, J., Marchionni,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.23 MB

english, 2014

20

Maximizing Return on Socioeconomic Investment in Phase II Proof-of-Concept Trials

Chen, C., Beckman, R. A.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 283 KB

english, 2014

21

Primate-Specific miR-663 Functions as a Tumor Suppressor by Targeting PIK3CD and Predicts the Prognosis of Human Glioblastoma

Shi, Y., Chen, C., Zhang, X., Liu, Q., Xu, J.-L., Zhang, H.-R., Yao, X.-H., Jiang, T., He, Z.-C., Ren, Y., Cui, W., Xu, C., Liu, L., Cui, Y.-H., Yu, S.-Z., Ping, Y.-F., Bian, X.-W.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.59 MB

english, 2014

22

A Phase I, Multicenter, Open-Label, First-in-Human, Dose-Escalation Study of the Oral Smoothened Inhibitor Sonidegib (LDE225) in Patients with Advanced Solid Tumors

Rodon, J., Tawbi, H. A., Thomas, A. L., Stoller, R. G., Turtschi, C. P., Baselga, J., Sarantopoulos, J., Mahalingam, D., Shou, Y., Moles, M. A., Yang, L., Granvil, C., Hurh, E., Rose, K. L., Amakye, D

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 568 KB

english, 2014

23

Aberrant Presentation of HPA-Reactive Carbohydrates Implies Selectin-Independent Metastasis Formation in Human Prostate Cancer

Lange, T., Kupfernagel, M., Wicklein, D., Gebauer, F., Maar, H., Brugge, K., Muller, I., Simon, R., Schlomm, T., Sauter, G., Schumacher, U.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.33 MB

english, 2014

24

Prediction of Survival in Resected Non-Small Cell Lung Cancer Using a Protein Expression-Based Risk Model: Implications for Personalized Chemoprevention and Therapy

Gold, K. A., Kim, E. S., Liu, D. D., Yuan, P., Behrens, C., Solis, L. M., Kadara, H., Rice, D. C., Wistuba, I. I., Swisher, S. G., Hofstetter, W. L., Lee, J. J., Hong, W. K.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 892 KB

english, 2014

25

Phase II Randomized Study of Figitumumab plus Docetaxel and Docetaxel Alone with Crossover for Metastatic Castration-Resistant Prostate Cancer

de Bono, J. S., Piulats, J. M., Pandha, H. S., Petrylak, D. P., Saad, F., Aparicio, L. M. A., Sandhu, S. K., Fong, P., Gillessen, S., Hudes, G. R., Wang, T., Scranton, J., Pollak, M. N.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 405 KB

english, 2014

26

Combination of YM155, a Survivin Suppressant, with Bendamustine and Rituximab: A New Combination Therapy to Treat Relapsed/Refractory Diffuse Large B-cell Lymphoma

Kaneko, N., Mitsuoka, K., Amino, N., Yamanaka, K., Kita, A., Mori, M., Miyoshi, S., Kuromitsu, S.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 482 KB

english, 2014

27

Seeing the Forest for the Trees: Kidney Oncogenomes in Relation to Therapeutic Outcomes

Chism, D. D., Rathmell, W. K.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 383 KB

english, 2014

28

Downregulation of FOXO3a Promotes Tumor Metastasis and Is Associated with Metastasis-Free Survival of Patients with Clear Cell Renal Cell Carcinoma

Ni, D., Ma, X., Li, H.-Z., Gao, Y., Li, X.-T., Zhang, Y., Ai, Q., Zhang, P., Song, E.-L., Huang, Q.-B., Fan, Y., Zhang, X.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.30 MB

english, 2014

29

Cross-talk between EphA2 and BRaf/CRaf Is a Key Determinant of Response to Dasatinib

Huang, J., Hu, W., Bottsford-Miller, J., Liu, T., Han, H. D., Zand, B., Pradeep, S., Roh, J.-W., Thanapprapasr, D., Dalton, H. J., Pecot, C. V., Rupaimoole, R., Lu, C., Fellman, B., Urbauer, D., Kang,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 2.39 MB

english, 2014

30

Having Pancreatic Cancer with Tumoral Loss of ATM and Normal TP53 Protein Expression Is Associated with a Poorer Prognosis

Kim, H., Saka, B., Knight, S., Borges, M., Childs, E., Klein, A., Wolfgang, C., Herman, J., Adsay, V. N., Hruban, R. H., Goggins, M.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 597 KB

english, 2014

31

T-cell Responses to Oncogenic Merkel Cell Polyomavirus Proteins Distinguish Patients with Merkel Cell Carcinoma from Healthy Donors

Lyngaa, R., Pedersen, N. W., Schrama, D., Thrue, C. A., Ibrani, D., Met, O., thor Straten, P., Nghiem, P., Becker, J. C., Hadrup, S. R.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 499 KB

english, 2014

32

Tumor Genetic Analyses of Patients with Metastatic Renal Cell Carcinoma and Extended Benefit from mTOR Inhibitor Therapy

Voss, M. H., Hakimi, A. A., Pham, C. G., Brannon, A. R., Chen, Y.-B., Cunha, L. F., Akin, O., Liu, H., Takeda, S., Scott, S. N., Socci, N. D., Viale, A., Schultz, N., Sander, C., Reuter, V. E., Russo,

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 708 KB

english, 2014

33

Is There Clinical Value to Prognostic Signatures in Early-Stage NSCLC?

Bunn, P. A., Hirsch, F. R., Aisner, D. L.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 243 KB

english, 2014

34

Novel Clinically Relevant Genes in GIST--Letter

Pantaleo, M. A., Nannini, M., Astolfi, A., Biasco, G.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 178 KB

english, 2014

35

Novel Clinically Relevant Genes in GIST--Response

Birner, P., Streubel, B.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 177 KB

english, 2014

36

AACR Celebrates 50 Years of Tobacco Research and Policy

Herbst, R. S., Hobin, J. A., Gritz, E. R.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 576 KB

english, 2014

37

It Shouldn't Take Another 50 Years: Accelerating Momentum to End the Tobacco Epidemic

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 188 KB

english, 2014