Volume 21; Issue 4

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Clinical Cancer Research
Volume 21; Issue 4

Clinical Cancer Research

Volume 21; Issue 4

1

Molecular Pathways: The PERKs and Pitfalls of Targeting the Unfolded Protein Response in Cancer

Maas, N. L., Diehl, J. A.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.71 MB

english, 2015

2

Evaluation of a Tumor Microenvironment-Based Prognostic Score in Primary Operable Colorectal Cancer

Park, J. H., McMillan, D. C., Powell, A. G., Richards, C. H., Horgan, P. G., Edwards, J., Roxburgh, C. S. D.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.26 MB

english, 2015

3

Integrative Analysis of Head and Neck Cancer Identifies Two Biologically Distinct HPV and Three Non-HPV Subtypes

Keck, M. K., Zuo, Z., Khattri, A., Stricker, T. P., Brown, C. D., Imanguli, M., Rieke, D., Endhardt, K., Fang, P., Bragelmann, J., DeBoer, R., El-Dinali, M., Aktolga, S., Lei, Z., Tan, P., Rozen, S. G

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 3.61 MB

english, 2015

4

Epithelial-Mesenchymal Transitioned Circulating Tumor Cells Capture for Detecting Tumor Progression

Satelli, A., Mitra, A., Brownlee, Z., Xia, X., Bellister, S., Overman, M. J., Kopetz, S., Ellis, L. M., Meng, Q. H., Li, S.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 18.74 MB

english, 2015

5

Stem Cells Increase in Numbers in Perinecrotic Areas in Human Renal Cancer

Varna, M., Gapihan, G., Feugeas, J.-P., Ratajczak, P., Tan, S., Ferreira, I., Leboeuf, C., Setterblad, N., Duval, A., Verine, J., Germain, S., Mongiat-Artus, P., Janin, A., Bousquet, G.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 8.08 MB

english, 2015

6

Antitumor Activity in RAS-Driven Tumors by Blocking AKT and MEK

Tolcher, A. W., Khan, K., Ong, M., Banerji, U., Papadimitrakopoulou, V., Gandara, D. R., Patnaik, A., Baird, R. D., Olmos, D., Garrett, C. R., Skolnik, J. M., Rubin, E. H., Smith, P. D., Huang, P., Le

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

7

Synergistic Activity of PARP Inhibition by Talazoparib (BMN 673) with Temozolomide in Pediatric Cancer Models in the Pediatric Preclinical Testing Program

Smith, M. A., Reynolds, C. P., Kang, M. H., Kolb, E. A., Gorlick, R., Carol, H., Lock, R. B., Keir, S. T., Maris, J. M., Billups, C. A., Lyalin, D., Kurmasheva, R. T., Houghton, P. J.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.90 MB

english, 2015

8

A Phase Ib Dose-Escalation Study of the Oral Pan-PI3K Inhibitor Buparlisib (BKM120) in Combination with the Oral MEK1/2 Inhibitor Trametinib (GSK1120212) in Patients with Selected Advanced Solid Tumors

Bedard, P. L., Tabernero, J., Janku, F., Wainberg, Z. A., Paz-Ares, L., Vansteenkiste, J., Van Cutsem, E., Perez-Garcia, J., Stathis, A., Britten, C. D., Le, N., Carter, K., Demanse, D., Csonka, D., P

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 629 KB

english, 2015

9

Ceritinib for the Treatment of Late-Stage (Metastatic) Non-Small Cell Lung Cancer

Massarelli, E., Papadimitrakopoulou, V.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 486 KB

english, 2015

10

DNMT1-MicroRNA126 Epigenetic Circuit Contributes to Esophageal Squamous Cell Carcinoma Growth via ADAM9-EGFR-AKT Signaling

Liu, R., Gu, J., Jiang, P., Zheng, Y., Liu, X., Jiang, X., Huang, E., Xiong, S., Xu, F., Liu, G., Ge, D., Chu, Y.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.50 MB

english, 2015

11

Immune Escape Mechanisms as a Guide for Cancer Immunotherapy

Beatty, G. L., Gladney, W. L.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 329 KB

english, 2015

12

Activation of Vitamin D Receptor Signaling Downregulates the Expression of Nuclear FOXM1 Protein and Suppresses Pancreatic Cancer Cell Stemness

Li, Z., Jia, Z., Gao, Y., Xie, D., Wei, D., Cui, J., Mishra, L., Huang, S., Zhang, Y., Xie, K.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.16 MB

english, 2015

13

A Tale of Two Receptors: Insulin and Insulin-Like Growth Factor Signaling in Cancer

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 401 KB

english, 2015

14

pVHL/HIF-Regulated CD70 Expression Is Associated with Infiltration of CD27+ Lymphocytes and Increased Serum Levels of Soluble CD27 in Clear Cell Renal Cell Carcinoma

Ruf, M., Mittmann, C., Nowicka, A. M., Hartmann, A., Hermanns, T., Poyet, C., van den Broek, M., Sulser, T., Moch, H., Schraml, P.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.23 MB

english, 2015

15

Molecular Pathways: Trafficking of Metabolic Resources in the Tumor Microenvironment

Romero, I. L., Mukherjee, A., Kenny, H. A., Litchfield, L. M., Lengyel, E.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 515 KB

english, 2015

16

Correction: Reduced p21WAF1/CIP1 via Alteration of p53-DDX3 Pathway Is Associated with Poor Relapse-Free Survival in Early-Stage Human Papillomavirus-Associated Lung Cancer

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 419 KB

english, 2015

17

Translational Impact of Nanoparticle-Drug Conjugate CRLX101 with or without Bevacizumab in Advanced Ovarian Cancer

Pham, E., Birrer, M. J., Eliasof, S., Garmey, E. G., Lazarus, D., Lee, C. R., Man, S., Matulonis, U. A., Peters, C. G., Xu, P., Krasner, C., Kerbel, R. S.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 961 KB

english, 2015

18

Breast Cancers with a BRCA1-like DNA Copy Number Profile Recur Less Often Than Expected after High-Dose Alkylating Chemotherapy

Schouten, P. C., Marme, F., Aulmann, S., Sinn, H.-P., van Essen, H. F., Ylstra, B., Hauptmann, M., Schneeweiss, A., Linn, S. C.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 607 KB

english, 2015

19

Aspirin, NSAIDs, and Risk of Prostate Cancer: Results from the REDUCE Study

Vidal, A. C., Howard, L. E., Moreira, D. M., Castro-Santamaria, R., Andriole, G. L., Freedland, S. J.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 243 KB

english, 2015

20

MET Amplification Status in Therapy-Naive Adeno- and Squamous Cell Carcinomas of the Lung

Schildhaus, H.-U., Schultheis, A. M., Ruschoff, J., Binot, E., Merkelbach-Bruse, S., Fassunke, J., Schulte, W., Ko, Y.-D., Schlesinger, A., Bos, M., Gardizi, M., Engel-Riedel, W., Brockmann, M., Serke

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.79 MB

english, 2015

21

Real-time, Near-Infrared Fluorescence Imaging with an Optimized Dye/Light Source/Camera Combination for Surgical Guidance of Prostate Cancer

Neuman, B. P., Eifler, J. B., Castanares, M., Chowdhury, W. H., Chen, Y., Mease, R. C., Ma, R., Mukherjee, A., Lupold, S. E., Pomper, M. G., Rodriguez, R.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.55 MB

english, 2015

22

DNA-PK--A Candidate Driver of Hepatocarcinogenesis and Tissue Biomarker That Predicts Response to Treatment and Survival

Cornell, L., Munck, J. M., Alsinet, C., Villanueva, A., Ogle, L., Willoughby, C. E., Televantou, D., Thomas, H. D., Jackson, J., Burt, A. D., Newell, D., Rose, J., Manas, D. M., Shapiro, G. I., Curtin

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.35 MB

english, 2015

23

Ang1 and Tie2 Are Predictive Biomarkers for Bevacizumab--Letter

Ciccolini, J., Serdjebi, C., Barbolosi, D., Lacarelle, B., Barlesi, F.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 134 KB

english, 2015

24

Vaccine-Induced Tumor Necrosis Factor-Producing T Cells Synergize with Cisplatin to Promote Tumor Cell Death

van der Sluis, T. C., van Duikeren, S., Huppelschoten, S., Jordanova, E. S., Beyranvand Nejad, E., Sloots, A., Boon, L., Smit, V. T. H. B. M., Welters, M. J. P., Ossendorp, F., van de Water, B., Arens

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.34 MB

english, 2015

25

A Phase I Study of DMS612, a Novel Bifunctional Alkylating Agent

Appleman, L. J., Balasubramaniam, S., Parise, R. A., Bryla, C., Redon, C. E., Nakamura, A. J., Bonner, W. M., Wright, J. J., Piekarz, R., Kohler, D. R., Jiang, Y., Belani, C. P., Eiseman, J., Chu, E.,

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.31 MB

english, 2015

26

Novel Actions of Next-Generation Taxanes Benefit Advanced Stages of Prostate Cancer

de Leeuw, R., Berman-Booty, L. D., Schiewer, M. J., Ciment, S. J., Den, R. B., Dicker, A. P., Kelly, W. K., Trabulsi, E. J., Lallas, C. D., Gomella, L. G., Knudsen, K. E.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.92 MB

english, 2015

27

Dual Inhibition of Bcr-Abl and Hsp90 by C086 Potently Inhibits the Proliferation of Imatinib-Resistant CML Cells

Wu, L., Yu, J., Chen, R., Liu, Y., Lou, L., Wu, Y., Huang, L., Fan, Y., Gao, P., Huang, M., Wu, Y., Chen, Y., Xu, J.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.83 MB

english, 2015

28

A Phase I Study of Continuous Oral Dosing of OSI-906, a Dual Inhibitor of Insulin-Like Growth Factor-1 and Insulin Receptors, in Patients with Advanced Solid Tumors

Puzanov, I., Lindsay, C. R., Goff, L., Sosman, J., Gilbert, J., Berlin, J., Poondru, S., Simantov, R., Gedrich, R., Stephens, A., Chan, E., Evans, T. R. J.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 391 KB

english, 2015

29

Systemic High-Dose Corticosteroid Treatment Does Not Improve the Outcome of Ipilimumab-Related Hypophysitis: A Retrospective Cohort Study

Min, L., Hodi, F. S., Giobbie-Hurder, A., Ott, P. A., Luke, J. J., Donahue, H., Davis, M., Carroll, R. S., Kaiser, U. B.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 344 KB

english, 2015

30

Recurrent PRDM10 Gene Fusions in Undifferentiated Pleomorphic Sarcoma

Hofvander, J., Tayebwa, J., Nilsson, J., Magnusson, L., Brosjo, O., Larsson, O., Vult von Steyern, F., Mandahl, N., Fletcher, C. D. M., Mertens, F.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 637 KB

english, 2015

31

Safety, Correlative Markers, and Clinical Results of Adjuvant Nivolumab in Combination with Vaccine in Resected High-Risk Metastatic Melanoma

Gibney, G. T., Kudchadkar, R. R., DeConti, R. C., Thebeau, M. S., Czupryn, M. P., Tetteh, L., Eysmans, C., Richards, A., Schell, M. J., Fisher, K. J., Horak, C. E., Inzunza, H. D., Yu, B., Martinez, A

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 849 KB

english, 2015

32

Phase I Study of Intermittent Oral Dosing of the Insulin-like Growth Factor-1 and Insulin Receptors Inhibitor OSI-906 in Patients With Advanced Solid Tumors

Jones, R. L., Kim, E. S., Nava-Parada, P., Alam, S., Johnson, F. M., Stephens, A. W., Simantov, R., Poondru, S., Gedrich, R., Lippman, S. M., Kaye, S. B., Carden, C. P.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 413 KB

english, 2015

33

CCR 20th Anniversary Commentary: Stayin' Alive--Antiapoptotic Proteins and Breast Cancer

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 223 KB

english, 2015