Volume 21; Issue 5

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Clinical Cancer Research
Volume 21; Issue 5

Clinical Cancer Research

Volume 21; Issue 5

1

Molecular Pathways: Linking Tumor Microenvironment to Epithelial-Mesenchymal Transition in Metastasis

Jung, H.-Y., Fattet, L., Yang, J.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 7.57 MB

english, 2015

2

Clinical Relevance of KRAS-Mutated Subclones Detected with Picodroplet Digital PCR in Advanced Colorectal Cancer Treated with Anti-EGFR Therapy

Laurent-Puig, P., Pekin, D., Normand, C., Kotsopoulos, S. K., Nizard, P., Perez-Toralla, K., Rowell, R., Olson, J., Srinivasan, P., Le Corre, D., Hor, T., El Harrak, Z., Li, X., Link, D. R., Bouche, O

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 706 KB

english, 2015

3

Molecular Pathways: Translational and Therapeutic Implications of the Notch Signaling Pathway in Cancer

Previs, R. A., Coleman, R. L., Harris, A. L., Sood, A. K.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 819 KB

english, 2015

4

Circulating Tumor Cell Analysis in Metastatic Triple-Negative Breast Cancers

Magbanua, M. J. M., Carey, L. A., DeLuca, A., Hwang, J., Scott, J. H., Rimawi, M. F., Mayer, E. L., Marcom, P. K., Liu, M. C., Esteva, F. J., Park, J. W., Rugo, H. S.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 624 KB

english, 2015

5

Targeting the Metabolic Plasticity of Multiple Myeloma with FDA-Approved Ritonavir and Metformin

Dalva-Aydemir, S., Bajpai, R., Martinez, M., Adekola, K. U. A., Kandela, I., Wei, C., Singhal, S., Koblinski, J. E., Raje, N. S., Rosen, S. T., Shanmugam, M.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

6

CDK 4/6 Inhibitor Palbociclib (PD0332991) in Rb+ Advanced Breast Cancer: Phase II Activity, Safety, and Predictive Biomarker Assessment

DeMichele, A., Clark, A. S., Tan, K. S., Heitjan, D. F., Gramlich, K., Gallagher, M., Lal, P., Feldman, M., Zhang, P., Colameco, C., Lewis, D., Langer, M., Goodman, N., Domchek, S., Gogineni, K., Rose

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 787 KB

english, 2015

7

A Serum MicroRNA Signature Predicts Tumor Relapse and Survival in Triple-Negative Breast Cancer Patients

Kleivi Sahlberg, K., Bottai, G., Naume, B., Burwinkel, B., Calin, G. A., Borresen-Dale, A.-L., Santarpia, L.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.08 MB

english, 2015

8

Nottingham Clinico-Pathological Response Index (NPRI) after Neoadjuvant Chemotherapy (Neo-ACT) Accurately Predicts Clinical Outcome in Locally Advanced Breast Cancer

Abdel-Fatah, T. M., Ball, G., Lee, A. H. S., Pinder, S., MacMilan, R. D., Cornford, E., Moseley, P. M., Silverman, R., Price, J., Latham, B., Palmer, D., Chan, A., Ellis, I. O., Chan, S. Y. T.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 3.74 MB

english, 2015

9

A Pilot Trial Using Lymphocytes Genetically Engineered with an NY-ESO-1-Reactive T-cell Receptor: Long-term Follow-up and Correlates with Response

Robbins, P. F., Kassim, S. H., Tran, T. L. N., Crystal, J. S., Morgan, R. A., Feldman, S. A., Yang, J. C., Dudley, M. E., Wunderlich, J. R., Sherry, R. M., Kammula, U. S., Hughes, M. S., Restifo, N. P

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

10

Integrin 6-Targeted Immunoliposomes Mediate Tumor-Specific Drug Delivery and Enhance Therapeutic Efficacy in Colon Carcinoma

Liang, B., Shahbaz, M., Wang, Y., Gao, H., Fang, R., Niu, Z., Liu, S., Wang, B., Sun, Q., Niu, W., Liu, E., Wang, J., Niu, J.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 14.91 MB

english, 2015

11

Raising the Bar for Antineoplastic Agents: How to Choose Threshold Values for Superiority Trials in Advanced Solid Tumors

Sobrero, A. F., Pastorino, A., Sargent, D. J., Bruzzi, P.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 656 KB

english, 2015

12

Epigenetics Markers of Metastasis and HPV-Induced Tumorigenesis in Penile Cancer

Feber, A., Arya, M., de Winter, P., Saqib, M., Nigam, R., Malone, P. R., Tan, W. S., Rodney, S., Lechner, M., Freeman, A., Jameson, C., Muneer, A., Beck, S., Kelly, J. D.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.58 MB

english, 2015

13

FDA Approval: Siltuximab for the Treatment of Patients with Multicentric Castleman Disease

Deisseroth, A., Ko, C.-W., Nie, L., Zirkelbach, J. F., Zhao, L., Bullock, J., Mehrotra, N., Del Valle, P., Saber, H., Sheth, C., Gehrke, B., Justice, R., Farrell, A., Pazdur, R.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 151 KB

english, 2015

14

Redifferentiation of Iodine-Refractory BRAF V600E-Mutant Metastatic Papillary Thyroid Cancer with Dabrafenib

Rothenberg, S. M., McFadden, D. G., Palmer, E. L., Daniels, G. H., Wirth, L. J.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 679 KB

english, 2015

15

Zebrafish: A New Companion for Translational Research in Oncology

Barriuso, J., Nagaraju, R., Hurlstone, A.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.91 MB

english, 2015

16

Immunomodulatory Antibody Therapy of Cancer: The Closer, the Better

Dronca, R. S., Dong, H.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 263 KB

english, 2015

17

Cancer Immunotherapy: A Future Paradigm Shift in the Treatment of Non-Small Cell Lung Cancer

Anagnostou, V. K., Brahmer, J. R.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 590 KB

english, 2015

18

Gene Expression Markers of Efficacy and Resistance to Cetuximab Treatment in Metastatic Colorectal Cancer: Results from CALGB 80203 (Alliance)

Cushman, S. M., Jiang, C., Hatch, A. J., Shterev, I., Sibley, A. B., Niedzwiecki, D., Venook, A. P., Owzar, K., Hurwitz, H. I., Nixon, A. B.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 719 KB

english, 2015

19

Patient-Derived Xenografts from Non-Small Cell Lung Cancer Brain Metastases Are Valuable Translational Platforms for the Development of Personalized Targeted Therapy

Lee, H. W., Lee, J.-i., Lee, S. J., Cho, H. J., Song, H. J., Jeong, D. E., Seo, Y. J., Shin, S., Joung, J.-G., Kwon, Y.-J., Choi, Y.-L., Park, W.-Y., Lee, H. M., Seol, H. J., Shim, Y. M., Joo, K. M.,

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.86 MB

english, 2015

20

Curing Mice with Large Tumors by Locally Delivering Combinations of Immunomodulatory Antibodies

Dai, M., Yip, Y. Y., Hellstrom, I., Hellstrom, K. E.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.08 MB

english, 2015

21

Neuregulin 1 Expression Is a Predictive Biomarker for Response to AV-203, an ERBB3 Inhibitory Antibody, in Human Tumor Models

Meetze, K., Vincent, S., Tyler, S., Mazsa, E. K., Delpero, A. R., Bottega, S., McIntosh, D., Nicoletti, R., Winston, W. M., Weiler, S., Feng, B., Gyuris, J., Weng, Z.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 408 KB

english, 2015

22

Activity of MM-398, Nanoliposomal Irinotecan (nal-IRI), in Ewing's Family Tumor Xenografts Is Associated with High Exposure of Tumor to Drug and High SLFN11 Expression

Kang, M. H., Wang, J., Makena, M. R., Lee, J.-S., Paz, N., Hall, C. P., Song, M. M., Calderon, R. I., Cruz, R. E., Hindle, A., Ko, W., Fitzgerald, J. B., Drummond, D. C., Triche, T. J., Reynolds, C. P

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.83 MB

english, 2015

23

Sonic Hedgehog and Gli1 Expression Predict Outcome in Resected Pancreatic Adenocarcinoma

Marechal, R., Bachet, J.-B., Calomme, A., Demetter, P., Delpero, J. R., Svrcek, M., Cros, J., Bardier-Dupas, A., Puleo, F., Monges, G., Hammel, P., Louvet, C., Paye, F., Bachelier, P., Le Treut, Y. P.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.57 MB

english, 2015

24

Correlation of PD-L1 Tumor Expression and Treatment Outcomes in Patients with Renal Cell Carcinoma Receiving Sunitinib or Pazopanib: Results from COMPARZ, a Randomized Controlled Trial

Choueiri, T. K., Figueroa, D. J., Fay, A. P., Signoretti, S., Liu, Y., Gagnon, R., Deen, K., Carpenter, C., Benson, P., Ho, T. H., Pandite, L., de Souza, P., Powles, T., Motzer, R. J.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 720 KB

english, 2015

25

Direct Serum Assay for Cell-Free Bmi-1 mRNA and Its Potential Diagnostic and Prognostic Value for Colorectal Cancer

Zhang, X., Yang, X., Zhang, Y., Liu, X., Zheng, G., Yang, Y., Wang, L., Du, L., Wang, C.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 714 KB

english, 2015

26

Longitudinal Noninvasive Imaging of Progesterone Receptor as a Predictive Biomarker of Tumor Responsiveness to Estrogen Deprivation Therapy

Chan, S. R., Fowler, A. M., Allen, J. A., Zhou, D., Dence, C. S., Sharp, T. L., Fettig, N. M., Dehdashti, F., Katzenellenbogen, J. A.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.26 MB

english, 2015

27

CCR 20th Anniversary Commentary: Preclinical Study of Proteasome Inhibitor Bortezomib in Head and Neck Cancer

Allen, C. T., Conley, B., Sunwoo, J. B., Van Waes, C.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 213 KB

english, 2015

28

A Phase I Study of PF-04449913, an Oral Hedgehog Inhibitor, in Patients with Advanced Solid Tumors

Wagner, A. J., Messersmith, W. A., Shaik, M. N., Li, S., Zheng, X., McLachlan, K. R., Cesari, R., Courtney, R., Levin, W. J., El-Khoueiry, A. B.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 418 KB

english, 2015

29

The Human Agonistic CD40 Antibody ADC-1013 Eradicates Bladder Tumors and Generates T-cell-Dependent Tumor Immunity

Mangsbo, S. M., Broos, S., Fletcher, E., Veitonmaki, N., Furebring, C., Dahlen, E., Norlen, P., Lindstedt, M., Totterman, T. H., Ellmark, P.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

30

Phase I Dose-Escalation Trial of the Oral Investigational Hedgehog Signaling Pathway Inhibitor TAK-441 in Patients with Advanced Solid Tumors

Goldman, J., Eckhardt, S. G., Borad, M. J., Curtis, K. K., Hidalgo, M., Calvo, E., Ryan, D. P., Wirth, L. J., Parikh, A., Partyka, J., Faessel, H., Gangolli, E., Stewart, S., Rosen, L. S., Bowles, D.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 762 KB

english, 2015

31

Moving from Evaluation to Value in Cancer Care

Schilsky, R. L.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 310 KB

english, 2015

32

Radiotherapy Combined with the Immunocytokine L19-IL2 Provides Long-lasting Antitumor Effects

Zegers, C. M. L., Rekers, N. H., Quaden, D. H. F., Lieuwes, N. G., Yaromina, A., Germeraad, W. T. V., Wieten, L., Biessen, E. A. L., Boon, L., Neri, D., Troost, E. G. C., Dubois, L. J., Lambin, P.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.15 MB

english, 2015

33

CCR 20th Anniversary Commentary: In the Beginning, There Was PS-341

Teicher, B. A., Anderson, K. C.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 414 KB

english, 2015

34

Angiogenic Cytokines Are Antibody Targets During Graft-versus-Leukemia Reactions

Piesche, M., Ho, V. T., Kim, H., Nakazaki, Y., Nehil, M., Yaghi, N. K., Kolodin, D., Weiser, J., Altevogt, P., Kiefel, H., Alyea, E. P., Antin, J. H., Cutler, C., Koreth, J., Canning, C., Ritz, J., So

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 572 KB

english, 2015

35

A Phase I Study of Oral ARRY-614, a p38 MAPK/Tie2 Dual Inhibitor, in Patients with Low or Intermediate-1 Risk Myelodysplastic Syndromes

Garcia-Manero, G., Khoury, H. J., Jabbour, E., Lancet, J., Winski, S. L., Cable, L., Rush, S., Maloney, L., Hogeland, G., Ptaszynski, M., Calvo, M. C., Bohannan, Z., List, A., Kantarjian, H., Komrokji

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 480 KB

english, 2015