Volume 21; Issue 6

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Clinical Cancer Research
Volume 21; Issue 6

Clinical Cancer Research

Volume 21; Issue 6

1

Steroid Sidestep: Evading Androgen Ablation by Abiraterone

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 309 KB

english, 2015

2

Safety and Efficacy of VCN-01, an Oncolytic Adenovirus Combining Fiber HSG-Binding Domain Replacement with RGD and Hyaluronidase Expression

Rodriguez-Garcia, A., Gimenez-Alejandre, M., Rojas, J. J., Moreno, R., Bazan-Peregrino, M., Cascallo, M., Alemany, R.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 987 KB

english, 2015

3

Molecular Pathways: Targeting the Dependence of Mutant RAS Cancers on the DNA Damage Response

Grabocka, E., Commisso, C., Bar-Sagi, D.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 516 KB

english, 2015

4

Abiraterone Treatment in Castration-Resistant Prostate Cancer Selects for Progesterone Responsive Mutant Androgen Receptors

Chen, E. J., Sowalsky, A. G., Gao, S., Cai, C., Voznesensky, O., Schaefer, R., Loda, M., True, L. D., Ye, H., Troncoso, P., Lis, R. L., Kantoff, P. W., Montgomery, R. B., Nelson, P. S., Bubley, G. J.,

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 384 KB

english, 2015

5

Prospective Validation of a New Method of Monitoring Minimal Residual Disease in Childhood Acute Myelogenous Leukemia

Steinbach, D., Bader, P., Willasch, A., Bartholomae, S., Debatin, K.-M., Zimmermann, M., Creutzig, U., Reinhardt, D., Gruhn, B.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 763 KB

english, 2015

6

Tumor-Associated Macrophages in SHH Subgroup of Medulloblastomas

Margol, A. S., Robison, N. J., Gnanachandran, J., Hung, L. T., Kennedy, R. J., Vali, M., Dhall, G., Finlay, J. L., Erdreich-Epstein, A., Krieger, M. D., Drissi, R., Fouladi, M., Gilles, F. H., Judkins

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.33 MB

english, 2015

7

Pathological Response and Circulating Tumor Cell Count Identifies Treated HER2+ Inflammatory Breast Cancer Patients with Excellent Prognosis: BEVERLY-2 Survival Data

Pierga, J.-Y., Petit, T., Levy, C., Ferrero, J.-M., Campone, M., Gligorov, J., Lerebours, F., Roche, H., Bachelot, T., Charafe-Jauffret, E., Bonneterre, J., Hernandez, J., Bidard, F.-C., Viens, P.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 384 KB

english, 2015

8

Impaired Self-Renewal and Increased Colitis and Dysplastic Lesions in Colonic Mucosa of AKR1B8-Deficient Mice

Shen, Y., Ma, J., Yan, R., Ling, H., Li, X., Yang, W., Gao, J., Huang, C., Bu, Y., Cao, Y., He, Y., Wan, L., Zu, X., Liu, J., Huang, M. C., Stenson, W. F., Liao, D.-F., Cao, D.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.07 MB

english, 2015

9

Effective Targeting of the P53-MDM2 Axis in Preclinical Models of Infant MLL-Rearranged Acute Lymphoblastic Leukemia

Richmond, J., Carol, H., Evans, K., High, L., Mendomo, A., Robbins, A., Meyer, C., Venn, N. C., Marschalek, R., Henderson, M., Sutton, R., Kurmasheva, R. T., Kees, U. R., Houghton, P. J., Smith, M. A.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 15.19 MB

english, 2015

10

Interleukin-6 as a Therapeutic Target

Rossi, J.-F., Lu, Z.-Y., Jourdan, M., Klein, B.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 4.00 MB

english, 2015

11

Pilot Trial of Combined BRAF and EGFR Inhibition in BRAF-Mutant Metastatic Colorectal Cancer Patients

Yaeger, R., Cercek, A., O'Reilly, E. M., Reidy, D. L., Kemeny, N., Wolinsky, T., Capanu, M., Gollub, M. J., Rosen, N., Berger, M. F., Lacouture, M. E., Vakiani, E., Saltz, L. B.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.72 MB

english, 2015

12

Gain of HIF-1 under Normoxia in Cancer Mediates Immune Adaptation through the AKT/ERK and VEGFA Axes

Lee, Y.-H., Bae, H. C., Noh, K. H., Song, K.-H., Ye, S.-k., Mao, C.-P., Lee, K.-M., Wu, T.- C., Kim, T. W.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 3.02 MB

english, 2015

13

Hedgehog Pathway Inhibitors Promote Adaptive Immune Responses in Basal Cell Carcinoma

Otsuka, A., Dreier, J., Cheng, P. F., Nageli, M., Lehmann, H., Felderer, L., Frew, I. J., Matsushita, S., Levesque, M. P., Dummer, R.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.16 MB

english, 2015

14

Pharmacodynamic Imaging Guides Dosing of a Selective Estrogen Receptor Degrader

Heidari, P., Deng, F., Esfahani, S. A., Leece, A. K., Shoup, T. M., Vasdev, N., Mahmood, U.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.46 MB

english, 2015

15

Tyrosine Kinase Inhibition in Leukemia Induces an Altered Metabolic State Sensitive to Mitochondrial Perturbations

Alvarez-Calderon, F., Gregory, M. A., Pham-Danis, C., DeRyckere, D., Stevens, B. M., Zaberezhnyy, V., Hill, A. A., Gemta, L., Kumar, A., Kumar, V., Wempe, M. F., Pollyea, D. A., Jordan, C. T., Serkova

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 4.11 MB

english, 2015

16

Genomic Analysis of Metastatic Cutaneous Squamous Cell Carcinoma

Li, Y. Y., Hanna, G. J., Laga, A. C., Haddad, R. I., Lorch, J. H., Hammerman, P. S.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 3.90 MB

english, 2015

17

Translational Implications of Tumor Heterogeneity

Jamal-Hanjani, M., Quezada, S. A., Larkin, J., Swanton, C.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 869 KB

english, 2015

18

Phase I Study of a Bispecific Ligand-Directed Toxin Targeting CD22 and CD19 (DT2219) for Refractory B-cell Malignancies

Bachanova, V., Frankel, A. E., Cao, Q., Lewis, D., Grzywacz, B., Verneris, M. R., Ustun, C., Lazaryan, A., McClune, B., Warlick, E. D., Kantarjian, H., Weisdorf, D. J., Miller, J. S., Vallera, D. A.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 724 KB

english, 2015

19

Phase I Trial of Cyclophosphamide as an Immune Modulator for Optimizing Oncolytic Reovirus Delivery to Solid Tumors

Roulstone, V., Khan, K., Pandha, H. S., Rudman, S., Coffey, M., Gill, G. M., Melcher, A. A., Vile, R., Harrington, K. J., de Bono, J., Spicer, J.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 955 KB

english, 2015

20

Molecular Subtypes of Clear Cell Renal Cell Carcinoma Are Associated with Sunitinib Response in the Metastatic Setting

Beuselinck, B., Job, S., Becht, E., Karadimou, A., Verkarre, V., Couchy, G., Giraldo, N., Rioux-Leclercq, N., Molinie, V., Sibony, M., Elaidi, R., Teghom, C., Patard, J.-J., Mejean, A., Fridman, W. H.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.23 MB

english, 2015

21

Cyclin-Dependent Kinase 5 Decreases in Gastric Cancer and Its Nuclear Accumulation Suppresses Gastric Tumorigenesis

Cao, L., Zhou, J., Zhang, J., Wu, S., Yang, X., Zhao, X., Li, H., Luo, M., Yu, Q., Lin, G., Lin, H., Xie, J., Li, P., Hu, X., Zheng, C., Bu, G., Zhang, Y.-w., Xu, H., Yang, Y., Huang, C., Zhang, J.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.26 MB

english, 2015

22

PEST Domain Mutations in Notch Receptors Comprise an Oncogenic Driver Segment in Triple-Negative Breast Cancer Sensitive to a -Secretase Inhibitor

Wang, K., Zhang, Q., Li, D., Ching, K., Zhang, C., Zheng, X., Ozeck, M., Shi, S., Li, X., Wang, H., Rejto, P., Christensen, J., Olson, P.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.22 MB

english, 2015

23

Potential Role of pNF-H, a Biomarker of Axonal Damage in the Central Nervous System, as a Predictive Marker of Chemotherapy-Induced Cognitive Impairment

Natori, A., Ogata, T., Sumitani, M., Kogure, T., Yamauchi, T., Yamauchi, H.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 243 KB

english, 2015

24

Trabectedin Efficacy in Ewing Sarcoma Is Greatly Increased by Combination with Anti-IGF Signaling Agents

Amaral, A. T., Garofalo, C., Frapolli, R., Manara, M. C., Mancarella, C., Uboldi, S., Giandomenico, S. D., Ordonez, J. L., Sevillano, V., Malaguarnera, R., Picci, P., Hassan, A. B., Alava, E. D., D'In

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.81 MB

english, 2015

25

Pharmacogenomic Modeling in Pancreatic Cancer--Response

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 125 KB

english, 2015

26

Pharmacogenomic Modeling in Pancreatic Cancer--Letter

Avan, A., Avan, A., Maftouh, M., Mobarhan, M. G., Gholamin, S.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 132 KB

english, 2015

27

A Comparative Study of Molecular Characteristics of Diffuse Large B-cell Lymphoma from Patients with and without Human Immunodeficiency Virus Infection

Chao, C., Silverberg, M. J., Xu, L., Chen, L.-H., Castor, B., Martinez-Maza, O., Abrams, D. I., Zha, H. D., Haque, R., Said, J.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 362 KB

english, 2015

28

Antibody-Mediated Delivery of Anti-KRAS-siRNA In Vivo Overcomes Therapy Resistance in Colon Cancer

Baumer, S., Baumer, N., Appel, N., Terheyden, L., Fremerey, J., Schelhaas, S., Wardelmann, E., Buchholz, F., Berdel, W. E., Muller-Tidow, C.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 8.99 MB

english, 2015

29

Clinical and Biological Effects of an Agonist Anti-CD40 Antibody: A Cancer Research UK Phase I Study

Johnson, P., Challis, R., Chowdhury, F., Gao, Y., Harvey, M., Geldart, T., Kerr, P., Chan, C., Smith, A., Steven, N., Edwards, C., Ashton-Key, M., Hodges, E., Tutt, A., Ottensmeier, C., Glennie, M., W

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 848 KB

english, 2015

30

Integrating RAS Status into Prognostic Signatures for Adenocarcinomas of the Lung

Starmans, M. H., Pintilie, M., Chan-Seng-Yue, M., Moon, N. C., Haider, S., Nguyen, F., Lau, S. K., Liu, N., Kasprzyk, A., Wouters, B. G., Der, S. D., Shepherd, F. A., Jurisica, I., Penn, L. Z., Tsao,

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.66 MB

english, 2015

31

A First-in-Human Phase I Study of MORAb-004, a Monoclonal Antibody to Endosialin in Patients with Advanced Solid Tumors

Diaz, L. A., Coughlin, C. M., Weil, S. C., Fishel, J., Gounder, M. M., Lawrence, S., Azad, N., O'Shannessy, D. J., Grasso, L., Wustner, J., Ebel, W., Carvajal, R. D.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 900 KB

english, 2015

32

Correction: TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 140 KB

english, 2015

33

CCR 20th Anniversary Commentary: BMS-247550--Microtubule Stabilization as Successful Targeted Therapy

Pabla, N., Sparreboom, A.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 434 KB

english, 2015

34

Correction: Silencing of Human Phosphatidylethanolamine-Binding Protein 4 Sensitizes Breast Cancer Cells to Tumor Necrosis Factor- -Induced Apoptosis and Cell Growth Arrest

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015