Volume 21; Issue 7

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Clinical Cancer Research
Volume 21; Issue 7

Clinical Cancer Research

Volume 21; Issue 7

1

Comprehensive Genomic Analysis Identifies Novel Subtypes and Targets of Triple-Negative Breast Cancer

Burstein, M. D., Tsimelzon, A., Poage, G. M., Covington, K. R., Contreras, A., Fuqua, S. A. W., Savage, M. I., Osborne, C. K., Hilsenbeck, S. G., Chang, J. C., Mills, G. B., Lau, C. C., Brown, P. H.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 16.59 MB

english, 2015

2

Translating the Molecular Message of Triple-Negative Breast Cancer into Targeted Therapy

Vidula, N., Rugo, H. S.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 492 KB

english, 2015

3

Pancreatic Cancer-Derived Exosomes Cause Paraneoplastic -cell Dysfunction

Javeed, N., Sagar, G., Dutta, S. K., Smyrk, T. C., Lau, J. S., Bhattacharya, S., Truty, M., Petersen, G. M., Kaufman, R. J., Chari, S. T., Mukhopadhyay, D.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 10.16 MB

english, 2015

4

A Novel CDC25B Promoter-Based Oncolytic Adenovirus Inhibited Growth of Orthotopic Human Pancreatic Tumors in Different Preclinical Models

Weber, H. L., Gidekel, M., Werbajh, S., Salvatierra, E., Rotondaro, C., Sganga, L., Haab, G. A., Curiel, D. T., Cafferata, E. G., Podhajcer, O. L.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 8.37 MB

english, 2015

5

KEAP1 Genetic Polymorphisms Associate with Breast Cancer Risk and Survival Outcomes

Hartikainen, J. M., Tengstrom, M., Winqvist, R., Jukkola-Vuorinen, A., Pylkas, K., Kosma, V.-M., Soini, Y., Mannermaa, A.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

6

DNMT3A Mutational Status Affects the Results of Dose-Escalated Induction Therapy in Acute Myelogenous Leukemia

Sehgal, A. R., Gimotty, P. A., Zhao, J., Hsu, J.-M., Daber, R., Morrissette, J. D., Luger, S., Loren, A. W., Carroll, M.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.25 MB

english, 2015

7

BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth

Wang, T., Xiao, M., Ge, Y., Krepler, C., Belser, E., Lopez-Coral, A., Xu, X., Zhang, G., Azuma, R., Liu, Q., Liu, R., Li, L., Amaravadi, R. K., Xu, W., Karakousis, G., Gangadhar, T. C., Schuchter, L.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 3.09 MB

english, 2015

8

Randomized Trial of Oral Cyclophosphamide and Veliparib in High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers, or BRCA-Mutant Ovarian Cancer

Kummar, S., Oza, A. M., Fleming, G. F., Sullivan, D. M., Gandara, D. R., Naughton, M. J., Villalona-Calero, M. A., Morgan, R. J., Szabo, P. M., Youn, A., Chen, A. P., Ji, J., Allen, D. E., Lih, C.-J.,

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 9.58 MB

english, 2015

9

Improvements in Radiographic Progression-Free Survival Stratified by ERG Gene Status in Metastatic Castration-Resistant Prostate Cancer Patients Treated with Abiraterone Acetate

Attard, G., de Bono, J. S., Logothetis, C. J., Fizazi, K., Mukherjee, S. D., Joshua, A. M., Schrijvers, D., van den Eertwegh, A. J. M., Li, W., Molina, A., Griffin, T. W., Kheoh, T., Ricci, D. S., Zel

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 264 KB

english, 2015

10

Sequence Variation in Mature MicroRNA-499 Confers Unfavorable Prognosis of Lung Cancer Patients Treated with Platinum-Based Chemotherapy

Qiu, F., Yang, L., Ling, X., Yang, R., Yang, X., Zhang, L., Fang, W., Xie, C., Huang, D., Zhou, Y., Lu, J.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 7.75 MB

english, 2015

11

Pancreatic Cancer-Associated Diabetes Is an "Exosomopathy"

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 795 KB

english, 2015

12

Loss of SOD3 (EcSOD) Expression Promotes an Aggressive Phenotype in Human Pancreatic Ductal Adenocarcinoma

O'Leary, B. R., Fath, M. A., Bellizzi, A. M., Hrabe, J. E., Button, A. M., Allen, B. G., Case, A. J., Altekruse, S., Wagner, B. A., Buettner, G. R., Lynch, C. F., Hernandez, B. Y., Cozen, W., Beardsle

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

13

Idelalisib: First-in-Class PI3K Delta Inhibitor for the Treatment of Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia, and Follicular Lymphoma

Yang, Q., Modi, P., Newcomb, T., Queva, C., Gandhi, V.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.78 MB

english, 2015

14

FDA Approval: Idelalisib Monotherapy for the Treatment of Patients with Follicular Lymphoma and Small Lymphocytic Lymphoma

Miller, B. W., Przepiorka, D., de Claro, R. A., Lee, K., Nie, L., Simpson, N., Gudi, R., Saber, H., Shord, S., Bullock, J., Marathe, D., Mehrotra, N., Hsieh, L. S., Ghosh, D., Brown, J., Kane, R. C.,

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 203 KB

english, 2015

15

Lung Master Protocol (Lung-MAP)--A Biomarker-Driven Protocol for Accelerating Development of Therapies for Squamous Cell Lung Cancer: SWOG S1400

Herbst, R. S., Gandara, D. R., Hirsch, F. R., Redman, M. W., LeBlanc, M., Mack, P. C., Schwartz, L. H., Vokes, E., Ramalingam, S. S., Bradley, J. D., Sparks, D., Zhou, Y., Miwa, C., Miller, V. A., Yel

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 546 KB

english, 2015

16

Generation 2.5 Antisense Oligonucleotides Targeting the Androgen Receptor and Its Splice Variants Suppress Enzalutamide-Resistant Prostate Cancer Cell Growth

Yamamoto, Y., Loriot, Y., Beraldi, E., Zhang, F., Wyatt, A. W., Nakouzi, N. A., Mo, F., Zhou, T., Kim, Y., Monia, B. P., MacLeod, A. R., Fazli, L., Wang, Y., Collins, C. C., Zoubeidi, A., Gleave, M.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.28 MB

english, 2015

17

Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal Cancer Patients Treated with 5-FU and Radiation

Bohanes, P., Rankin, C. J., Blanke, C. D., Winder, T., Ulrich, C. M., Smalley, S. R., Rich, T. A., Martensen, J. A., Benson, A. B., Mayer, R. J., Cripps, C. M., Danenberg, K., Makar, K. W., Zhang, W.,

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 913 KB

english, 2015

18

The BET Bromodomain Inhibitor OTX015 Affects Pathogenetic Pathways in Preclinical B-cell Tumor Models and Synergizes with Targeted Drugs

Boi, M., Gaudio, E., Bonetti, P., Kwee, I., Bernasconi, E., Tarantelli, C., Rinaldi, A., Testoni, M., Cascione, L., Ponzoni, M., Mensah, A. A., Stathis, A., Stussi, G., Riveiro, M. E., Herait, P., Ing

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 8.24 MB

english, 2015

19

Cross-Species Antibody Microarray Interrogation Identifies a 3-Protein Panel of Plasma Biomarkers for Early Diagnosis of Pancreas Cancer

Mirus, J. E., Zhang, Y., Li, C. I., Lokshin, A. E., Prentice, R. L., Hingorani, S. R., Lampe, P. D.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 5.75 MB

english, 2015

20

Molecular Pathways: Aspirin and Wnt Signaling--A Molecularly Targeted Approach to Cancer Prevention and Treatment

Gala, M. K., Chan, A. T.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 9.86 MB

english, 2015

21

Association of Antigen-Specific T-cell Responses with Antigen Expression and Immunoparalysis in Multiple Myeloma

Fichtner, S., Hose, D., Engelhardt, M., Meissner, T., Neuber, B., Krasniqi, F., Raab, M., Schonland, S., Ho, A. D., Goldschmidt, H., Hundemer, M.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.17 MB

english, 2015

22

Nonviral Oncogenic Antigens and the Inflammatory Signals Driving Early Cancer Development as Targets for Cancer Immunoprevention

Chu, N. J., Armstrong, T. D., Jaffee, E. M.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.33 MB

english, 2015

23

Correction: TRAIL and Doxorubicin Combination Induces Proapoptotic and Antiangiogenic Effects in Soft Tissue Sarcoma In Vivo

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 769 KB

english, 2015

24

Global Promoter Methylation Analysis Reveals Novel Candidate Tumor Suppressor Genes in Natural Killer Cell Lymphoma

Kucuk, C., Hu, X., Jiang, B., Klinkebiel, D., Geng, H., Gong, Q., Bouska, A., Iqbal, J., Gaulard, P., McKeithan, T. W., Chan, W. C.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 944 KB

english, 2015

25

Habitual Myofibrillar Protein Synthesis Is Normal in Patients with Upper GI Cancer Cachexia

MacDonald, A. J., Johns, N., Stephens, N., Greig, C., Ross, J. A., Small, A. C., Husi, H., Fearon, K. C. H., Preston, T.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 433 KB

english, 2015

26

A Phase I Study of Cixutumumab (IMC-A12) in Combination with Temsirolimus (CCI-779) in Children with Recurrent Solid Tumors: A Children's Oncology Group Phase I Consortium Report

Fouladi, M., Perentesis, J. P., Wagner, L. M., Vinks, A. A., Reid, J. M., Ahern, C., Thomas, G., Mercer, C. A., Krueger, D. A., Houghton, P. J., Doyle, L. A., Chen, H., Weigel, B., Blaney, S. M.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 305 KB

english, 2015

27

Conditional Survival: A Useful Concept to Provide Information on How Prognosis Evolves over Time

Hieke, S., Kleber, M., Konig, C., Engelhardt, M., Schumacher, M.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 915 KB

english, 2015

28

A Phase I Study of CUDC-101, a Multitarget Inhibitor of HDACs, EGFR, and HER2, in Combination with Chemoradiation in Patients with Head and Neck Squamous Cell Carcinoma

Galloway, T. J., Wirth, L. J., Colevas, A. D., Gilbert, J., Bauman, J. E., Saba, N. F., Raben, D., Mehra, R., Ma, A. W., Atoyan, R., Wang, J., Burtness, B., Jimeno, A.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 142 KB

english, 2015

29

BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs

Liu, Z., Wei, P., Yang, Y., Cui, W., Cao, B., Tan, C., Yu, B., Bi, R., Xia, K., Chen, W., Wang, Y., Zhang, Y., Du, X., Zhou, X.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.15 MB

english, 2015

30

The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4

Liu, L., Mayes, P. A., Eastman, S., Shi, H., Yadavilli, S., Zhang, T., Yang, J., Seestaller-Wehr, L., Zhang, S.-Y., Hopson, C., Tsvetkov, L., Jing, J., Zhang, S., Smothers, J., Hoos, A.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.47 MB

english, 2015

31

CCR 20th Anniversary Commentary: In Search of Cetuximab's First Indication--Combination Therapy with Irinotecan in Colorectal Cancer

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 231 KB

english, 2015

32

Correction: Molecular Pathways: Targeting the Kinase Effectors of RHO-Family GTPases

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 137 KB

english, 2015

33

Correction: Combining PCI-24781, a Novel Histone Deacetylase Inhibitor, with Chemotherapy for the Treatment of Soft Tissue Sarcoma

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 579 KB

english, 2015