Volume 86; Issue 6

Clinical Pharmacology & Therapeutics

Volume 86; Issue 6

1

Current Understanding of the Pharmacogenomics of Metformin

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 163 KB

english, 2009

2

Risk to the Breast-Fed Neonate From Codeine Treatment to the Mother: A Quantitative Mechanistic Modeling Study

Willmann, S, Edginton, A N, Coboeken, K, Ahr, G, Lippert, J

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 328 KB

english, 2009

3

The Road From Discovery to Clinic: Adiponectin as a Biomarker of Metabolic Status

Kusminski, C M, Scherer, P E

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 297 KB

english, 2009

4

Orally Administered Glucagon-Like Peptide-1 Affects Glucose Homeostasis Following an Oral Glucose Tolerance Test in Healthy Male Subjects

Steinert, R E, Poller, B, Castelli, M C, Friedman, K, Huber, A R, Drewe, J, Beglinger, C

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 192 KB

english, 2009

5

Comparison of Native E. coli and PEG Asparaginase Pharmacokinetics and Pharmacodynamics in Pediatric Acute Lymphoblastic Leukemia

Panetta, J C, Gajjar, A, Hijiya, N, Hak, L J, Cheng, C, Liu, W, Pui, C H, Relling, M V

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 338 KB

english, 2009

6

Do NSAIDs Actually Protect Against Myocardial Infarction and Death?

van Beers, E J, de Groot, J R, Tijssen, J G P

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 82 KB

english, 2009

7

Potent and Selective Agonism of the Melanocortin Receptor 4 With MK-0493 Does Not Induce Weight Loss in Obese Human Subjects: Energy Intake Predicts Lack of Weight Loss Efficacy

Krishna, R, Gumbiner, B, Stevens, C, Musser, B, Mallick, M, Suryawanshi, S, Maganti, L, Zhu, H, Han, T H, Scherer, L

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 209 KB

english, 2009

8

Genetic Influences on the Pharmacokinetics of Orally and Intravenously Administered Digoxin as Exhibited by Monozygotic Twins

Birkenfeld, A L, Jordan, J, Hofmann, U, Busjahn, A, Franke, G, Krüger, N, Igel, S, Mürdter, T, Drescher, S, Shi, S

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 138 KB

english, 2009

9

ERRATUM: The Role of Ethnicity in Variability in Response to Drugs: Focus on Clinical Pharmacology Studies

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 39 KB

english, 2009

10

Clinical Trial Design in Neonatal Pharmacology: Effect of Center Differences, With Lessons From the Pediatric Oncology Cooperative Research Experience

Cohen-Wolkowiez, M, Benjamin, D K, Moran, C, Smith, P B

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 90 KB

english, 2009

11

CORRIGENDUM: Effects of Selective Serotonin Reuptake Inhibitor Therapy on Endothelial Function and Inflammatory Markers in Patients With Coronary Heart Disease

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 39 KB

english, 2009

12

Pediatric Drug Development: Concepts and Applications

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 86 KB

english, 2009

13

Developmental Pharmacogenetics: A General Paradigm for Application to Neonatal Pharmacology and Toxicology

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 208 KB

english, 2009

14

Clinical Trial Simulations in Pediatric Patients Using Realistic Covariates: Application to Teduglutide, a Glucagon-Like Peptide-2 Analog in Neonates and Infants With Short-Bowel Syndrome

Mouksassi, M S, Marier, J F, Cyran, J, Vinks, A A

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 397 KB

english, 2009

15

Sustained Neurobehavioral Effects of Exposure to SSRI Antidepressants During Development: Molecular to Clinical Evidence

Oberlander, T F, Gingrich, J A, Ansorge, M S

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 142 KB

english, 2009

16

Response to “No Obvious Extra Cardiovascular Risk Associated With Low-Dose NSAIDs,” “Do NSAIDs Actually Protect Against Myocardial Infarction and Death?,” and “Are Myocardial Infarctions and Death in Healthy Individuals Associated With the Use of Cyclooxygenase Inhibitors?”

Fosbøl, E L, Gislason, G H, Køber, L, Torp-Pedersen, C

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 82 KB

english, 2009

17

Clinical Trials in Neonates: A Therapeutic Imperative

Ward, R M, Kern, S E

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 99 KB

english, 2009

18

Population Pharmacokinetics and Pharmacogenetics of Tacrolimus in De Novo Pediatric Kidney Transplant Recipients

Zhao, W, Elie, V, Roussey, G, Brochard, K, Niaudet, P, Leroy, V, Loirat, C, Cochat, P, Cloarec, S, André, J L

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 220 KB

english, 2009

19

Can We Afford It?: Ethical Consideration of Expensive Drug Treatment for Neonates and Infants

Zlotnik Shaul, R, Vitale, D

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 99 KB

english, 2009

20

Neonatal Pharmacology: Rational Therapeutics for the Most Vulnerable

James, L, Ito, S

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 98 KB

english, 2009

21

ASCPT News

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 277 KB

english, 2009

22

In This Issue

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 100 KB

english, 2009

23

Highlights

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 361 KB

english, 2009

24

Are Myocardial Infarctions and Death in Healthy Individuals Associated With the Use of Cyclooxygenase Inhibitors?

Renner, B, Brune, K

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 91 KB

english, 2009

25

No Obvious Extra Cardiovascular Risk Associated With Low-Dose NSAIDs

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 83 KB

english, 2009

26

Utility of Adiponectin as a Biomarker Predictive of Glycemic Efficacy Is Demonstrated by Collaborative Pooling of Data From Clinical Trials Conducted by Multiple Sponsors

Wagner, J A, Wright, E C, Ennis, M M, Prince, M, Kochan, J, Nunez, D J R, Schneider, B, Wang, M-D, Chen, Y, Ghosh, S

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 333 KB

english, 2009

27

Escitalopram Is a Weak Inhibitor of the CYP2D6-Catalyzed O-Demethylation of (+)-Tramadol but Does Not Reduce the Hypoalgesic Effect in Experimental Pain

Noehr-Jensen, L, Zwisler, S T, Larsen, F, Sindrup, S H, Damkier, P, Brosen, K

Journal:

Clinical Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 209 KB

english, 2009

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