Fundraising September 15, 2024 – October 1, 2024 About fundraising

Volume 87; Issue 5

Clinical Pharmacology & Therapeutics

Volume 87; Issue 5

1

The Biomarkers Consortium: Practice and Pitfalls of Open-Source Precompetitive Collaboration

Wagner, J A, Prince, M, Wright, E C, Ennis, M M, Kochan, J, Nunez, D J R, Schneider, B, Wang, M-D, Chen, Y, Ghosh, S

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 179 KB

english, 2010

2

ABCG2 Polymorphism Is Associated With the Low-Density Lipoprotein Cholesterol Response to Rosuvastatin

Tomlinson, B, Hu, M, Lee, V W Y, Lui, S S H, Chu, T T W, Poon, E W M, Ko, G T C, Baum, L, Tam, L S, Li, E K

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 150 KB

english, 2010

3

Effects of the Selective α1A-Adrenoceptor Antagonist Silodosin on ECGs of Healthy Men in a Randomized, Double-Blind, Placebo- and Moxifloxacin-Controlled Study

Morganroth, J, Lepor, H, Hill, L A, Volinn, W, Hoel, G

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 160 KB

english, 2010

4

Targeted Cancer Therapies in the Twenty-First Century: Lessons From Imatinib

Stegmeier, F, Warmuth, M, Sellers, W R, Dorsch, M

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 191 KB

english, 2010

5

Regional P-Glycoprotein Activity and Inhibition at the Human Blood–Brain Barrier as Imaged by Positron Emission Tomography

Eyal, S, Ke, B, Muzi, M, Link, J M, Mankoff, D A, Collier, A C, Unadkat, J D

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 329 KB

english, 2010

6

Biodistribution of 89Zr-trastuzumab and PET Imaging of HER2-Positive Lesions in Patients With Metastatic Breast Cancer

Dijkers, E C, Oude Munnink, T H, Kosterink, J G, Brouwers, A H, Jager, P L, de Jong, J R, van Dongen, G A, Schröder, C P, Lub-de Hooge, M N, de Vries, E G

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 309 KB

english, 2010

7

Integration of Genetic, Clinical, and INR Data to Refine Warfarin Dosing

Lenzini, P, Wadelius, M, Kimmel, S, Anderson, J L, Jorgensen, A L, Pirmohamed, M, Caldwell, M D, Limdi, N, Burmester, J K, Dowd, M B

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 185 KB

english, 2010

8

Orexin Receptor Antagonism, a New Sleep-Promoting Paradigm: An Ascending Single-Dose Study With Almorexant

Hoever, P, de Haas, S, Winkler, J, Schoemaker, R C, Chiossi, E, van Gerven, J, Dingemanse, J

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 1.21 MB

english, 2010

9

Pharmacokinetic/Pharmacodynamic Modeling of Biomarker Response to Sunitinib in Healthy Volunteers

Lindauer, A, Di Gion, P, Kanefendt, F, Tomalik-Scharte, D, Kinzig, M, Rodamer, M, Dodos, F, Sörgel, F, Fuhr, U, Jaehde, U

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 331 KB

english, 2010

10

How Informatics Can Potentiate Precompetitive Open-Source Collaboration to Jump-Start Drug Discovery and Development

Perakslis, E D, Van Dam, J, Szalma, S

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 144 KB

english, 2010

11

ASCPT News

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 236 KB

english, 2010

12

Can Open-Source Drug R&D Repower Pharmaceutical Innovation?

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 143 KB

english, 2010

13

The Critical Path Institute’s Approach to Precompetitive Sharing and Advancing Regulatory Science

Woosley, R L, Myers, R T, Goodsaid, F

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 432 KB

english, 2010

14

Precompetitive Research: A New Prescription for Drug Development?

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 69 KB

english, 2010

15

The Future Is Much Closer Collaboration Between the Pharmaceutical Industry and Academic Medical Centers

Vallance, P, Williams, P, Dollery, C

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 158 KB

english, 2010

16

Genetic Variation in Nicotine Metabolism Predicts the Efficacy of Extended-Duration Transdermal Nicotine Therapy

Lerman, C, Jepson, C, Wileyto, E P, Patterson, F, Schnoll, R, Mroziewicz, M, Benowitz, N, Tyndale, R F

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 156 KB

english, 2010

17

Arguments Against Precompetitive Collaboration

Vargas, G, Boutouyrie, B, Ostrowitzki, S, Santarelli, L

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 145 KB

english, 2010

18

Open-Minded to Open Innovation and Precompetitive Collaboration

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 138 KB

english, 2010

19

The Need for Precompetitive Integrative Bionetwork Disease Model Building

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 280 KB

english, 2010

20

In This Issue

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 154 KB

english, 2010

21

Highlights

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 556 KB

english, 2010

22

Adaptive-Optimal Design in PET Occupancy Studies

Zamuner, S, Di Iorio, V L, Nyberg, J, Gunn, R N, Cunningham, V J, Gomeni, R, Hooker, A C

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 253 KB

english, 2010