Volume 90; Issue 1

Clinical Pharmacology & Therapeutics

Volume 90; Issue 1

1

Genetically Polymorphic OCT1: Another Piece in the Puzzle of the Variable Pharmacokinetics and Pharmacodynamics of the Opioidergic Drug Tramadol

Tzvetkov, M V, Saadatmand, A R, Lötsch, J, Tegeder, I, Stingl, J C, Brockmöller, J

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 1.58 MB

english, 2011

2

Sensitivity of Intravenous and Oral Alfentanil and Pupillary Miosis as Minimal and Noninvasive Probes for Hepatic and First-Pass CYP3A Induction

Kharasch, E D, Francis, A, London, A, Frey, K, Kim, T, Blood, J

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 1.37 MB

english, 2011

3

Alendronate Adherence and Its Impact on Hip-Fracture Risk in Patients With Established Osteoporosis in Taiwan

Lin, T-C, Yang, C-Y, Kao Yang, Y-H, Lin, S-J

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 635 KB

english, 2011

4

Impact of Smoking, Smoking Cessation, and Genetic Polymorphisms on CYP1A2 Activity and Inducibility

Dobrinas, M, Cornuz, J, Oneda, B, Kohler Serra, M, Puhl, M, Eap, C B

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 794 KB

english, 2011

5

Predicting Adverse Drug Reactions Using Publicly Available PubChem BioAssay Data

Pouliot, Y, Chiang, A P, Butte, A J

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 1.82 MB

english, 2011

6

Detecting Drug Interactions From Adverse-Event Reports: Interaction Between Paroxetine and Pravastatin Increases Blood Glucose Levels

Tatonetti, N P, Denny, J C, Murphy, S N, Fernald, G H, Krishnan, G, Castro, V, Yue, P, Tsau, P S, Kohane, I, Roden, D M

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 2.01 MB

english, 2011

7

Childhood Obesity: A Ticking Time Bomb for Cardiovascular Disease?

Logue, J, Sattar, N

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 537 KB

english, 2011

8

Obesity, the Metabolic Syndrome, and Sexual Dysfunction in Men

Esposito, K, Giugliano, D

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 1.04 MB

english, 2011

9

A Randomized Study of the Efficacy and Safety of Intravenous Acetaminophen vs. Intravenous Placebo for the Treatment of Fever

Kett, D H, Breitmeyer, J B, Ang, R, Royal, M A

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 520 KB

english, 2011

10

Mechanisms and Genetics of Antipsychotic-Associated Weight Gain

Balt, S L, Galloway, G P, Baggott, M J, Schwartz, Z, Mendelson, J

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 199 KB

english, 2011

11

Biomarkers for the Prediction of Type 2 Diabetes and Cardiovascular Disease

Herder, C, Karakas, M, Koenig, W

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 211 KB

english, 2011

12

Pharmacokinetic Impact of SLCO1A2 Polymorphisms on Imatinib Disposition in Patients With Chronic Myeloid Leukemia

Yamakawa, Y, Hamada, A, Shuto, T, Yuki, M, Uchida, T, Kai, H, Kawaguchi, T, Saito, H

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 192 KB

english, 2011

13

The Human Placental Perfusion Model: A Systematic Review and Development of a Model to Predict In Vivo Transfer of Therapeutic Drugs

Hutson, J R, Garcia-Bournissen, F, Davis, A, Koren, G

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 1.57 MB

english, 2011

14

Implications of Obesity for Drug Therapy: Limitations and Challenges

Jain, R, Chung, S M, Jain, L, Khurana, M, Lau, S W J, Lee, J E, Vaidyanathan, J, Zadezensky, I, Choe, S, Sahajwalla, C G

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 272 KB

english, 2011

15

New Drug Targets for the Treatment of Obesity

Powell, A G, Apovian, C M, Aronne, L J

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 226 KB

english, 2011

16

The Obesity Paradox in Heart Failure: Accepting Reality and Making Rational Decisions

Anker, S D, von Haehling, S

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 80 KB

english, 2011

17

Population Pharmacokinetic-Pharmacodynamic Analysis of Trastuzumab-Associated Cardiotoxicity

van Hasselt, J G C, Boekhout, A H, Beijnen, J H, Schellens, J H M, Huitema, A D R

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 205 KB

english, 2011

18

Cigarette Smoking, Nicotine, and Body Weight

Audrain-McGovern, J, Benowitz, N L

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 166 KB

english, 2011

19

Clinical Pharmacology as a Foundation for Translational Science

Waldman, S A, Hohl, R J, Kearns, G L, Swan, S J, Terzic, A

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

File:

PDF, 71 KB

2011

20

Clinical Pharmacology as a Foundation for Translational Science

Waldman, S A, Hohl, R J, Kearns, G L, Swan, S J, Terzic, A

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 71 KB

english, 2011

21

The Paradox of Obesity and Cardiovascular Disease Risk: Time to Change Labels

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 95 KB

english, 2011

22

The Male Genital Tract Is Not a Pharmacological Sanctuary From Efavirenz

Avery, L B, Bakshi, R P, Cao, Y J, Hendrix, C W

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 147 KB

english, 2011

23

Dietary Management of the Metabolic Syndrome

Kimokoti, R W, Brown, L S

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 97 KB

english, 2011

24

The Metabolic Syndrome: Looking Beyond the Debates

Prabhakaran, D, Reddy, K S

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 90 KB

english, 2011

25

The Importance of High-Quality Evidence of the Long-Term Impact of Nonfatal Events Used in Randomized Controlled Trials: A Case Study of Prasugrel

Lu, C Y, Karnon, J, Sorich, M J

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 127 KB

english, 2011

26

Practical Ethics: Establishing a Pathway to Benefit for Complex Pharmacogenomic Tests

Haga, S B, Burke, W

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 92 KB

english, 2011

27

Regulatory Science as a Bridge Between Science and Society

Tominaga, T, Asahina, Y, Uyama, Y, Kondo, T

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 144 KB

english, 2011

28

In This Issue

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 105 KB

english, 2011

29

ASCPT News

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 193 KB

english, 2011

30

ASCPT News

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 250 KB

english, 2011

31

Highlights

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 369 KB

english, 2011