Volume 90; Issue 5

Clinical Pharmacology & Therapeutics

Volume 90; Issue 5

1

Genetic Variants of Interferon-Stimulated Genes and IL-28B as Host Prognostic Factors of Response to Combination Treatment for Chronic Hepatitis C

Lopez-Rodriguez, R, Trapero-Marugan, M, Borque, M J, Roman, M, Hernandez-Bartolome, A, Rodriguez-Muñoz, Y, Martin-Vilchez, S, Abad-Santos, F, Muñoz de Rueda, P, Vidal-Castiñeira, J R, Rodrigo, L, Salm

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 275 KB

english, 2011

2

Hidden Administration of Drugs

Benedetti, F, Carlino, E, Pollo, A

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 653 KB

english, 2011

3

Linking Pharmacology to Clinical Reports: Cyclobenzaprine and Its Possible Association With Serotonin Syndrome

Mestres, J, Seifert, S A, Oprea, T I

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 129 KB

english, 2011

4

Mechanisms Involved in Placebo and Nocebo Responses and Implications for Drug Trials

Rief, W, Bingel, U, Schedlowski, M, Enck, P

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 166 KB

english, 2011

5

Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of JNJ-38431055, a Novel GPR119 Receptor Agonist and Potential Antidiabetes Agent, in Healthy Male Subjects

Katz, L B, Gambale, J J, Rothenberg, P L, Vanapalli, S R, Vaccaro, N, Xi, L, Polidori, D C, Vets, E, Sarich, T C, Stein, P P

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 192 KB

english, 2011

6

Plasma Letrozole Concentrations in Postmenopausal Women With Breast Cancer Are Associated With CYP2A6 Genetic Variants, Body Mass Index, and Age

Desta, Z, Kreutz, Y, Nguyen, A T, Li, L, Skaar, T, Kamdem, L K, Henry, N L, Hayes, D F, Storniolo, A M, Stearns, V, Hoffmann, E, Tyndale, R F, Flockhart, D A

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 247 KB

english, 2011

7

A Common 5′-UTR Variant in MATE2-K Is Associated With Poor Response to Metformin

Choi, J H, Yee, S W, Ramirez, A H, Morrissey, K M, Jang, G H, Joski, P J, Mefford, J A, Hesselson, S E, Schlessinger, A, Jenkins, G, Castro, R A, Johns, S J, Stryke, D, Sali, A, Ferrin, T E, Witte, J

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 440 KB

english, 2011

8

A Proposal for an Individualized Pharmacogenetics-Based Warfarin Initiation Dose Regimen for Patients Commencing Anticoagulation Therapy

Avery, P J, Jorgensen, A, Hamberg, A K, Wadelius, M, Pirmohamed, M, Kamali, F

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 206 KB

english, 2011

9

Developing a Valid Patient-Reported Outcome Measure

Rothrock, N E, Kaiser, K A, Cella, D

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 164 KB

english, 2011

10

Response to “Commercial Factors Override Science in Combination Addiction Drug Trial”

Strain, E C, Harrison, J A, Bigelow, G E

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 55 KB

english, 2011

11

In This Issue

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 63 KB

english, 2011

12

Determining the Time Course of CYP3A Inhibition by Potent Reversible and Irreversible CYP3A Inhibitors Using A Limited Sampling Strategy

Katzenmaier, S, Markert, C, Riedel, K-D, Burhenne, J, Haefeli, W E, Mikus, G

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 243 KB

english, 2011

13

Blinding in Randomized Clinical Trials: Imposed Impartiality

Hróbjartsson, A, Boutron, I

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 103 KB

english, 2011

14

Registration of Observational Studies Does Not Enhance Validity

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 94 KB

english, 2011

15

Acetaminophen Metabolism After Major Surgery: A Greater Challenge With Increasing Age

Pickering, G, Schneider, E, Papet, I, Pujos-Guillot, E, Pereira, B, Simen, E, Dubray, C, Schoeffler, P

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 140 KB

english, 2011

16

Placebo in Clinical Trials

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 72 KB

english, 2011

17

StaR Child Health: Developing Evidence-Based Guidance for the Design, Conduct, and Reporting of Pediatric Trials

Hartling, L, Wittmeier, K D M, Caldwell, P H, van der Lee, J H, Klassen, T P, Craig, J C, Offringa, M

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 238 KB

english, 2011

18

Highlights

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 321 KB

english, 2011

19

Integration of Diverse Data Sources for Prediction of Adverse Drug Events

Abernethy, D R, Bai, J P F, Burkhart, K, Xie, H-G, Zhichkin, P

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 84 KB

english, 2011

20

Commercial Factors Override Science in Combination Addiction Drug Trial

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 54 KB

english, 2011

21

The Patient-Reported Outcome (PRO) Consortium: Filling Measurement Gaps for PRO End Points to Support Labeling Claims

Coons, S J, Kothari, S, Monz, B U, Burke, L B

Journal:

Clinical Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 119 KB

english, 2011