Clinical Therapeutics

1

Potential Health Care Cost Savings Associated With Early Treatment of Multiple Sclerosis Using Disease-Modifying Therapy

Suellen M. Curkendall, Cheng Wang, Barbara H. Johnson, Zhun Cao, Ronald Preblick, Amelito M. Torres, Volker Knappertz, Kathleen Gondek

Journal:

Year:

2011

Language:

english

File:

PDF, 691 KB

english, 2011

2

Pharmacokinetics of Oral Cyanocobalamin Formulated With Sodium N-[8-(2-hydroxybenzoyl)amino]caprylate (SNAC): An Open-Label, Randomized, Single-Dose, Parallel-Group Study in Healthy Male Subjects

M. Cristina Castelli, Diane F. Wong, Kristen Friedman, M. Gary I. Riley

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 443 KB

english, 2011

3

A Comparative Analysis of the Impact of a Positive List System on New Chemical Entity Drugs and Incrementally Modified Drugs in South Korea

DongMun Ha, Yong Choi, Dae Up Kim, Kyu Hyuck Chung, Eui-Kyung Lee

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 449 KB

english, 2011

4

Impact of Drug Label Changes on Propofol Use in Pediatrics for Moderate Conscious Sedation

Pamela C. Heaton, Joseph Schuchter, Carole M. Lannon, Alex R. Kemper

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 735 KB

english, 2011

5

Glycemic Control With Insulin Glargine Plus Insulin Glulisine Versus Premixed Insulin Analogues in Real-World Practices: A Cost-Effectiveness Study With a Randomized Pragmatic Trial Design

Philip A. Levin, Quanwu Zhang, James H. Mersey, Francis Y. Lee, Lee A. Bromberger, Madhu Bhushan, Rajat Bhushan

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 309 KB

english, 2011

6

A Placebo- and Active-Controlled Assessment of 6- and 50-mg Oral Doxepin on Cardiac Repolarization in Healthy Volunteers: A Thorough QT Evaluation

Robert S. Mansbach, Elizabeth Ludington, Roberta Rogowski, Jeffrey P. Kittrelle, Philip Jochelson

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 900 KB

english, 2011

7

Efficacy and Tolerability of Self-Titrated Biphasic Insulin Aspart 70/30 in Patients Aged >65 Years With Type 2 Diabetes: An Exploratory Post Hoc Subanalysis of the INITIATEplus Trial

David S. Oyer, Mark D. Shepherd, Franklin C. Coulter, Anuj Bhargava, Antonio J. DeLuzio, Pei-Ling Chu, Bruce S. Trippe

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 424 KB

english, 2011

8

Repeated and Escalating Preoperative Subanesthetic Doses of Ketamine for Postoperative Pain Control in Patients Undergoing Tumor Resection: A Randomized, Placebo-Controlled, Double-Blind Trial

Evgeny Rakhman, Dmitri Shmain, Ian White, Margaret P. Ekstein, Yehuda Kollender, Shoshana Chazan, Solomon Dadia, Jacob Bickels, Eyal Amar, Avi A. Weinbroum

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 874 KB

english, 2011

9

Measurement and Rates of Persistence With and Adherence to Biologics for Rheumatoid Arthritis: A Systematic Review

Marissa A. Blum, Danielle Koo, Jalpa A. Doshi

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 316 KB

english, 2011

10

Pharmacokinetic Properties of Infliximab in Children and Adults with Crohn's Disease: A Retrospective Analysis of Data from 2 Phase III Clinical Trials

Adedigbo A. Fasanmade, Omoniyi J. Adedokun, Marion Blank, Honghui Zhou, Hugh M. Davis

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 2.41 MB

english, 2011

11

Pharmacokinetic Comparison of Orally Disintegrating and Conventional Donepezil Formulations in Healthy Korean Male Subjects: A Single-Dose, Randomized, Open-Label, 2-Sequence, 2-Period Crossover Study

Kyoung-Ah Kim, Jong Lae Lim, Chin Kim, Ji-Young Park

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 501 KB

english, 2011

12

Review of the Therapeutic Uses of Liraglutide

Gina J. Ryan, Karla T. Foster, Lynetta Johnson Jobe

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 878 KB

english, 2011

13

Pharmacokinetic, Pharmacodynamic, and Tolerability Profiles of the Dipeptidyl Peptidase-4 Inhibitor Linagliptin: A 4-Week Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase IIa Study in Japanese Type 2 Diabetes Patients

Yoshiharu Horie, Shigeto Kanada, Hirotaka Watada, Akiko Sarashina, Atsushi Taniguchi, Naoyuki Hayashi, Eva U. Graefe-Mody, Hans-Juergen Woerle, Klaus A. Dugi

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 1.18 MB

english, 2011

14

Immunologic Effects and Tolerability Profile of In-Season Initiation of a Standardized-Quality Grass Allergy Immunotherapy Tablet: A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial in Adults with Grass Pollen–Induced Rhinoconjunctivitis

Kristian Reich, Christian Gessner, Axel Kroker, Jan Alexander Schwab, Wolfgang Pohl, Hanne Villesen, Eike Wüstenberg, Waltraud Emminger

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 459 KB

english, 2011

15

Rifaximin: New Therapeutic Indication and Future Directions

Anastasia Rivkin, Suzanna Gim

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 382 KB

english, 2011

16

Use of Patient Versus Population Preferences in Economic Evaluations of Health Care Interventions

James W. Shaw

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 96 KB

english, 2011

17

Letter to the Editor

Jan Matthys, Marc De Meyere

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 72 KB

english, 2011

18

Response to the Letter to the Editor

Elena Chiappini, Maurizio de Martino

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 77 KB

english, 2011

19

Editorial Board

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 35 KB

english, 2011

21

Editorial Board

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 29 KB

english, 2011

Volume 33; Issue 7

Potential Health Care Cost Savings Associated With Early Treatment of Multiple Sclerosis Using Disease-Modifying Therapy

Pharmacokinetics of Oral Cyanocobalamin Formulated With Sodium N-[8-(2-hydroxybenzoyl)amino]caprylate (SNAC): An Open-Label, Randomized, Single-Dose, Parallel-Group Study in Healthy Male Subjects

A Comparative Analysis of the Impact of a Positive List System on New Chemical Entity Drugs and Incrementally Modified Drugs in South Korea

Impact of Drug Label Changes on Propofol Use in Pediatrics for Moderate Conscious Sedation

Glycemic Control With Insulin Glargine Plus Insulin Glulisine Versus Premixed Insulin Analogues in Real-World Practices: A Cost-Effectiveness Study With a Randomized Pragmatic Trial Design

A Placebo- and Active-Controlled Assessment of 6- and 50-mg Oral Doxepin on Cardiac Repolarization in Healthy Volunteers: A Thorough QT Evaluation

Efficacy and Tolerability of Self-Titrated Biphasic Insulin Aspart 70/30 in Patients Aged >65 Years With Type 2 Diabetes: An Exploratory Post Hoc Subanalysis of the INITIATEplus Trial

Repeated and Escalating Preoperative Subanesthetic Doses of Ketamine for Postoperative Pain Control in Patients Undergoing Tumor Resection: A Randomized, Placebo-Controlled, Double-Blind Trial

Measurement and Rates of Persistence With and Adherence to Biologics for Rheumatoid Arthritis: A Systematic Review

Pharmacokinetic Properties of Infliximab in Children and Adults with Crohn's Disease: A Retrospective Analysis of Data from 2 Phase III Clinical Trials

Pharmacokinetic Comparison of Orally Disintegrating and Conventional Donepezil Formulations in Healthy Korean Male Subjects: A Single-Dose, Randomized, Open-Label, 2-Sequence, 2-Period Crossover Study

Review of the Therapeutic Uses of Liraglutide

Pharmacokinetic, Pharmacodynamic, and Tolerability Profiles of the Dipeptidyl Peptidase-4 Inhibitor Linagliptin: A 4-Week Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase IIa Study in Japanese Type 2 Diabetes Patients

Immunologic Effects and Tolerability Profile of In-Season Initiation of a Standardized-Quality Grass Allergy Immunotherapy Tablet: A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial in Adults with Grass Pollen–Induced Rhinoconjunctivitis

Rifaximin: New Therapeutic Indication and Future Directions

Use of Patient Versus Population Preferences in Economic Evaluations of Health Care Interventions

Letter to the Editor

Response to the Letter to the Editor

Table of Contents

Editorial Board

Editorial Board