Volume 34; Issue 5

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Clinical Therapeutics
Volume 34; Issue 5

Clinical Therapeutics

Volume 34; Issue 5

1

Differences in the In Vitro and In Vivo Pharmacokinetic Profiles of Once-Daily Modified-Release Methylphenidate Formulations in Canada: Examination of Current Bioequivalence Criteria

Megan J. Shram, Anne Marie Quinn, Nancy Chen, Janice Faulknor, Doanh Luong, Edward M. Sellers, Laszlo Endrenyi

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 482 KB

english, 2012

2

Belimumab: Review of Use in Systemic Lupus Erythematosus

Eric G. Boyce, Bryan E. Fusco

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 504 KB

english, 2012

3

Review of Linagliptin for the Treatment of Type 2 Diabetes Mellitus

Joshua J. Neumiller, Stephen M. Setter

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 425 KB

english, 2012

4

Effect of Exenatide, Pen Insulin, and Vial Insulin on Patient Outcomes: A Retrospective Database Analysis of Persistence and First-Year Costs in a Commercially Insured Population

Nazia Rashid, Jeffrey S. McCombs, Elizabeth Schwartz

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 359 KB

english, 2012

5

The Effect of Levodopa on Pulmonary Function in Parkinson's Disease: A Systematic Review and Meta-Analysis

Larissa Monteiro, Adelmir Souza-Machado, Silvia Valderramas, Ailton Melo

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 363 KB

english, 2012

6

Asenapine: A Clinical Review of a Second-Generation Antipsychotic

Steven C. Stoner, Heather A. Pace

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 540 KB

english, 2012

7

Safety Profile and Tolerability of Up to 1 Year of Pregabalin Treatment in 3 Open-Label Extension Studies in Patients With Fibromyalgia

Lesley M. Arnold, Birol Emir, T. Kevin Murphy, Bernhardt G. Zeiher, Lynne Pauer, Gayle Scott, Danielle Petersel

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 429 KB

english, 2012

8

Cost-Effectiveness Analysis of Interferon Beta-1b for the Treatment of Patients With a First Clinical Event Suggestive of Multiple Sclerosis

John P. Caloyeras, Bin Zhang, Cheng Wang, Marianne Eriksson, Sten Fredrikson, Karola Beckmann, Volker Knappertz, Christoph Pohl, Hans-Peter Hartung, Dhvani Shah, Jeffrey D. Miller, Rupert Sandbrink, V

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 882 KB

english, 2012

9

Utility of Interferon-γ Release Assay Results to Monitor Anti-Tubercular Treatment in Adults and Children

Elena Chiappini, Francesca Fossi, Francesca Bonsignori, Sara Sollai, Luisa Galli, Maurizio de Martino

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 317 KB

english, 2012

10

The Safety Profile of Dalfampridine Extended Release in Multiple Sclerosis Clinical Trials

David R. Cornblath, E. Jay Bienen, Andrew R. Blight

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 584 KB

english, 2012

11

Tacrolimus Versus Intravenous Pulse Cyclophosphamide Therapy in Chinese Adults With Steroid-Resistant Idiopathic Minimal Change Nephropathy: A Multicenter, Open-Label, Nonrandomized Cohort Trial

Heng Li, Xiangdong Shi, Hong Shen, Xiayu Li, Huiping Wang, Hongmei Li, Guangbiao Xu, Jianghua Chen

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 506 KB

english, 2012

12

Pharmacokinetic and Pharmacodynamic Properties of the Calcimimetic Agent Cinacalcet (KRN1493) in Healthy Male Korean Subjects: A Randomized, Open-Label, Single Ascending–Dose, Parallel-Group Study

SeungHwan Lee, Namyi Gu, Bo-Hyung Kim, Kyoung Soo Lim, Sang-Goo Shin, In-Jin Jang, Kyung-Sang Yu

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 713 KB

english, 2012

13

A Randomized, Double-Blind, Parallel, Single-Site Pilot Trial to Compare Two Different Starting Doses of Methotrexate in Methotrexate-Naïve Adult Patients with Rheumatoid Arthritis

Eva-Luise Hobl, Robert M. Mader, Bernd Jilma, Bernhard Duhm, Monika Mustak, Hans Bröll, Petra Högger, Ludwig Erlacher

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 320 KB

english, 2012

14

Efficacy and Tolerability of a 20-mg Dose of Methylphenidate for the Treatment of Daytime Sleepiness in Adult Patients With Myotonic Dystrophy Type 1: A 2-Center, Randomized, Double-Blind, Placebo-Controlled, 3-Week Crossover Trial

Jack Puymirat, Jean-Pierre Bouchard, Jean Mathieu

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 311 KB

english, 2012

15

Effects of Ketoconazole and Rifampicin on the Pharmacokinetics of Gemigliptin, a Dipeptidyl Peptidase-IV Inhibitor: A Crossover Drug–Drug Interaction Study in Healthy Male Korean Volunteers

Yook-Hwan Noh, Hyeong-Seok Lim, Seok-Joon Jin, Mi Jo Kim, Yo Han Kim, Hye Ryoung Sung, Hee Youn Choi, Kyun-Seop Bae

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 849 KB

english, 2012

16

Are Selective Serotonin Reuptake Inhibitors Safe for Drivers? What is the Evidence?

Silvia Ravera, Johannes G. Ramaekers, Lolkje T.W. de Jong-van den Berg, Johan J. de Gier

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 438 KB

english, 2012

17

Failure to Intensify Hypertension Therapy After Rejected Aliskiren Claims

Feng Zeng, Jinhee Park, Craig A. Plauschinat, Bimal V. Patel

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 309 KB

english, 2012

18

Impact of a Text Messaging Pilot Program on Patient Medication Adherence

Kalee F. Foreman, Karen M. Stockl, Lisa B. Le, Eric Fisk, Sameer M. Shah, Heidi C. Lew, Brian K. Solow, Bradford S. Curtis

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 214 KB

english, 2012

19

Fraud or flawed ? At the end of the day it may be the patient who pays the bill !

Peter Kranke, Jan Wallenborn, Norbert Roewer, Leopold H.J. Eberhart

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 120 KB

english, 2012

20

The authors respond

Derek H. Tang, Daniel C. Malone

Journal:

Clinical Therapeutics

Year:

2012

Language:

english

File:

PDF, 113 KB

english, 2012