Volume 3; Issue 1

npj Aging and Mechanisms of Disease

Volume 3; Issue 1

1

Conserved and species-specific molecular denominators in mammalian skeletal muscle aging

Mercken, Evi M., Capri, Miriam, Carboneau, Bethany A., Conte, Maria, Heidler, Juliana, Santoro, Aurelia, Martin-Montalvo, Alejandro, Gonzalez-Freire, Marta, Khraiwesh, Husam, González-Reyes, José A.,

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 7.44 MB

english, 2017

2

Identification of transcription factors that promote the differentiation of human pluripotent stem cells into lacrimal gland epithelium-like cells

Hirayama, Masatoshi, Ko, Shigeru B.H., Kawakita, Tetsuya, Akiyama, Tomohiko, Goparaju, Sravan K., Soma, Atsumi, Nakatake, Yuhki, Sakota, Miki, Chikazawa-Nohtomi, Nana, Shimmura, Shigeto, Tsubota, Kazu

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 3.51 MB

english, 2017

3

Functionally and morphologically damaged mitochondria observed in auditory cells under senescence-inducing stress

Kamogashira, Teru, Hayashi, Ken, Fujimoto, Chisato, Iwasaki, Shinichi, Yamasoba, Tatsuya

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 3.23 MB

english, 2017

4

Ubiquitous overexpression of the DNA repair factor dPrp19 reduces DNA damage and extends Drosophila life span

Garschall, Kathrin, Dellago, Hanna, Gáliková, Martina, Schosserer, Markus, Flatt, Thomas, Grillari, Johannes

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 896 KB

english, 2017

5

Opposing activities of oncogenic MIR17HG and tumor suppressive MIR100HG clusters and their gene targets regulate replicative senescence in human adult stem cells

Lopez, Mary F., Niu, Ping, Wang, Lu, Vogelsang, Maryann, Gaur, Meenakshi, Krastins, Bryan, Zhao, Yueqiang, Smagul, Aibek, Nussupbekova, Aliya, Akanov, Aikan A., Jordan, I. King, Lunyak, Victoria V.

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 2.97 MB

english, 2017

6

An alanine expanded PABPN1 causes increased utilization of intronic polyadenylation sites

Abbassi-Daloii, Tooba, Yousefi, Soheil, de Klerk, Eleonora, Grossouw, Laurens, Riaz, Muhammad, ’t Hoen, Peter A. C., Raz, Vered

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 1.31 MB

english, 2017

7

Global rise of potential health hazards caused by blue light-induced circadian disruption in modern aging societies

Hatori, Megumi, Gronfier, Claude, Van Gelder, Russell N., Bernstein, Paul S., Carreras, Josep, Panda, Satchidananda, Marks, Frederick, Sliney, David, Hunt, Charles E., Hirota, Tsuyoshi, Furukawa, Tosh

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 332 KB

english, 2017

8

Both overlapping and independent mechanisms determine how diet and insulin-ligand knockouts extend lifespan of Drosophila melanogaster

Zandveld, Jelle, van den Heuvel, Joost, Zwaan, Bastiaan J., Piper, Matthew D.W.

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 1.05 MB

english, 2017

9

Message from the new Co-Editor-in-Chief

Imai, Shin-ichiro

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 205 KB

english, 2017

10

SMARCD1 regulates senescence-associated lipid accumulation in hepatocytes

Inoue, Chisato, Zhao, Chong, Tsuduki, Yumi, Udono, Miyako, Wang, Lixiang, Nomura, Masatoshi, Katakura, Yoshinori

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 1.78 MB

english, 2017

11

Treatment of diabetic mice with the SGLT2 inhibitor TA-1887 antagonizes diabetic cachexia and decreases mortality

Sugizaki, Taichi, Zhu, Shunshun, Guo, Ge, Matsumoto, Akiko, Zhao, Jiabin, Endo, Motoyoshi, Horiguchi, Haruki, Morinaga, Jun, Tian, Zhe, Kadomatsu, Tsuyoshi, Miyata, Keishi, Itoh, Hiroshi, Oike, Yuichi

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 3.19 MB

english, 2017

12

Somatic growth, aging, and longevity

Bartke, Andrzej

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 622 KB

english, 2017

13

Periodontitis induced by bacterial infection exacerbates features of Alzheimer’s disease in transgenic mice

Ishida, Naoyuki, Ishihara, Yuichi, Ishida, Kazuto, Tada, Hiroyuki, Funaki-Kato, Yoshiko, Hagiwara, Makoto, Ferdous, Taslima, Abdullah, Mohammad, Mitani, Akio, Michikawa, Makoto, Matsushita, Kenji

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 975 KB

english, 2017

14

Health benefits of late-onset metformin treatment every other week in mice

Alfaras, Irene, Mitchell, Sarah J., Mora, Hector, Lugo, Darisbeth Rosario, Warren, Alessandra, Navas-Enamorado, Ignacio, Hoffmann, Vickie, Hine, Christopher, Mitchell, James R., Le Couteur, David G.,

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 4.03 MB

english, 2017

15

Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study

Dellinger, Ryan W., Santos, Santiago Roel, Morris, Mark, Evans, Mal, Alminana, Dan, Guarente, Leonard, Marcotulli, Eric

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 641 KB

english, 2017

16

Neuroprotective role of retinal SIRT3 against acute photo-stress

Ban, Norimitsu, Ozawa, Yoko, Osada, Hideto, Lin, Jonathan B., Toda, Eriko, Watanabe, Mitsuhiro, Yuki, Kenya, Kubota, Shunsuke, Apte, Rajendra S., Tsubota, Kazuo

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 1.82 MB

english, 2017

17

Cytochrome b5 protects photoreceptors from light stress-induced lipid peroxidation and retinal degeneration

Chen, Xinping, Hall, Hana, Simpson, Jeffrey P., Leon-Salas, Walter D., Ready, Donald F., Weake, Vikki M.

Journal:

npj Aging and Mechanisms of Disease

Year:

2017

Language:

english

File:

PDF, 2.52 MB

english, 2017

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