Volume 12; Issue 5

Controlled Clinical Trials

Volume 12; Issue 5
1

Suspended judgment the optimistic bias favoring medical action

Year:
1991
Language:
english
File:
PDF, 190 KB
english, 1991
5

Society for clinical trials: Board of directors, officers 1991–1992

Year:
1991
Language:
english
File:
PDF, 55 KB
english, 1991
9

Monotone spline additive-risks model

Year:
1991
Language:
english
File:
PDF, 66 KB
english, 1991
10

A comparison of odds ratio and relative risk models for binary data

Year:
1991
Language:
english
File:
PDF, 66 KB
english, 1991
13

Use of relational database “views” in clinical trial data management

Year:
1991
Language:
english
File:
PDF, 147 KB
english, 1991
14

Low cost database management in clinical trials—Riding the tidal wave of technology

Year:
1991
Language:
english
File:
PDF, 71 KB
english, 1991
15

A new clinical trials design for aids research: The “measured-choice” design

Year:
1991
Language:
english
File:
PDF, 71 KB
english, 1991
17

Clinical trials of investigational antiepileptic drugs: Monotherapy designs

Year:
1991
Language:
english
File:
PDF, 69 KB
english, 1991
25

Post-stratification approach to missing data problems in clinical trials

Year:
1991
Language:
english
File:
PDF, 74 KB
english, 1991
27

Statistical controversies in meta-analysis: Fixed effects or random effects models?

Year:
1991
Language:
english
File:
PDF, 72 KB
english, 1991
28

Recent developments in statistical methods for evaluating uniformity of treatment effects

Year:
1991
Language:
english
File:
PDF, 72 KB
english, 1991
29

Estimating subgroup treatment effects in clinical trials

Year:
1991
Language:
english
File:
PDF, 140 KB
english, 1991
30

Multicenter trials: Analysis with treatment by center interactions

Year:
1991
Language:
english
File:
PDF, 69 KB
english, 1991
32

Investigation of aickins measure of agreement

Year:
1991
Language:
english
File:
PDF, 81 KB
english, 1991
34

The changing role of a project manager during a multicenter clinical trial

Year:
1991
Language:
english
File:
PDF, 77 KB
english, 1991
35

Inter-data center and inter-group collaboration: The EORTC experience

Year:
1991
Language:
english
File:
PDF, 77 KB
english, 1991
42

Analysis of repeated measures in clinical trials using summary statistics

Year:
1991
Language:
english
File:
PDF, 67 KB
english, 1991
47

Publication practices in NIH-sponsored multicenter clinical trials

Year:
1991
Language:
english
File:
PDF, 84 KB
english, 1991
49

Results from clinical trials: How should they influence other ongoing clinical studies?

Year:
1991
Language:
english
File:
PDF, 69 KB
english, 1991
51

Facing unexpected major interaction—Results from a trial on graves' disease

Year:
1991
Language:
english
File:
PDF, 69 KB
english, 1991
53

The choice of sequential boundaries based on the concept of power spending

Year:
1991
Language:
english
File:
PDF, 73 KB
english, 1991
54

A conditional probability sequential stopping rule for clinical trials

Year:
1991
Language:
english
File:
PDF, 73 KB
english, 1991
55

Stochastic curtailment—or when should we stop or continue a clinical trial?

Year:
1991
Language:
english
File:
PDF, 73 KB
english, 1991
56

Sample size for sequentially monitored trials with noncompliance and lag

Year:
1991
Language:
english
File:
PDF, 77 KB
english, 1991
60

The relative importance of prognostic factors in studies of survival

Year:
1991
Language:
english
File:
PDF, 68 KB
english, 1991
62

Measuring screening biases in case fatality analyses with clinical trial data

Year:
1991
Language:
english
File:
PDF, 74 KB
english, 1991
63

Modelling morbidity of major diseases in a community from a delphi-type data

Year:
1991
Language:
english
File:
PDF, 74 KB
english, 1991
64

Teaching probabilistic expert system using clinical data

Year:
1991
Language:
english
File:
PDF, 150 KB
english, 1991
65

Use of an artificial neural network for statistical pattern recognition

Year:
1991
Language:
english
File:
PDF, 78 KB
english, 1991
66

Model selection procedures in analyzing case-control studies

Year:
1991
Language:
english
File:
PDF, 78 KB
english, 1991
67

Using the accrual period to update sample size estimates in prevention studies

Year:
1991
Language:
english
File:
PDF, 159 KB
english, 1991
70

Sample size and power for comparing vaccines

Year:
1991
Language:
english
File:
PDF, 70 KB
english, 1991
71

How to show the equivalence of two vaccines in a clinical trial

Year:
1991
Language:
english
File:
PDF, 70 KB
english, 1991
72

Competence, control, confirmation and refutation

Year:
1991
Language:
english
File:
PDF, 70 KB
english, 1991
73

Datafax evaluated

Year:
1991
Language:
english
File:
PDF, 76 KB
english, 1991
74

Towards a standardization of DDE

Year:
1991
Language:
english
File:
PDF, 76 KB
english, 1991
76

Electronic clinical trials in a group of UN community doctors

Year:
1991
Language:
english
File:
PDF, 84 KB
english, 1991
77

Using the foxpro code generator in the development of a distributed data entry system

Year:
1991
Language:
english
File:
PDF, 153 KB
english, 1991
78

Shared quality control in a distributed data entry system

Year:
1991
Language:
english
File:
PDF, 70 KB
english, 1991
79

Statistical methods for analyzing heart rate irregularity during atrial fibrillation

Year:
1991
Language:
english
File:
PDF, 70 KB
english, 1991
80

Analysis of the circadian blood pressure curve in normal men

Year:
1991
Language:
english
File:
PDF, 144 KB
english, 1991
83

The benefits of producing data collection forms the hard way

Year:
1991
Language:
english
File:
PDF, 73 KB
english, 1991
88

Too many trials with too small sample sizes

Year:
1991
Language:
english
File:
PDF, 77 KB
english, 1991
89

Sample sizes of prevention trials have been too small

Year:
1991
Language:
english
File:
PDF, 159 KB
english, 1991
90

Factors affecting the sample size benefits of run-in strategies

Year:
1991
Language:
english
File:
PDF, 84 KB
english, 1991
93

Problems of covariate adjustment in clinical trials

Year:
1991
Language:
english
File:
PDF, 71 KB
english, 1991
94

Subsampling strategies in clinical trials

Year:
1991
Language:
english
File:
PDF, 143 KB
english, 1991
95

The role of quality of life assessments in clinical trials

Year:
1991
Language:
english
File:
PDF, 74 KB
english, 1991
96

A comparison of quality-of-life measures in a randomized trial

Year:
1991
Language:
english
File:
PDF, 74 KB
english, 1991
98

Quality of life evaluation in clinical trials in cancer medicine

Year:
1991
Language:
english
File:
PDF, 76 KB
english, 1991
100

Implementation of concentration-controlled trials (CCTs)

Year:
1991
Language:
english
File:
PDF, 82 KB
english, 1991
101

A Bayesian approach to the design of phase II clinical trials

Year:
1991
Language:
english
File:
PDF, 82 KB
english, 1991
102

A phase II design for therapies which may be ineffective

Year:
1991
Language:
english
File:
PDF, 154 KB
english, 1991
104

Meta-analyses of animal experiments

Year:
1991
Language:
english
File:
PDF, 74 KB
english, 1991
108

A study of patient accrual patterns in 23 VA multicenter clinical trials

Year:
1991
Language:
english
File:
PDF, 73 KB
english, 1991
110

Phase I trials: Is it better to use patients or normal volunteers?

Year:
1991
Language:
english
File:
PDF, 144 KB
english, 1991
112

Serial correlation in the design and analysis of crossover trials

Year:
1991
Language:
english
File:
PDF, 72 KB
english, 1991
114

Block designs with neighbor correlations

Year:
1991
Language:
english
File:
PDF, 73 KB
english, 1991
115

Statistical issues addressed in a large screening trial

Year:
1991
Language:
english
File:
PDF, 73 KB
english, 1991
116

Statistical models for correlated responses in graft patency assessment

Year:
1991
Language:
english
File:
PDF, 73 KB
english, 1991
117

An analysis strategy for multi-dose combination drug clinical trials

Year:
1991
Language:
english
File:
PDF, 81 KB
english, 1991
118

A comparative study of non-randomized and randomized controls

Year:
1991
Language:
english
File:
PDF, 81 KB
english, 1991
119

Guidelines for simultaneous participation in two or more randomized trials

Year:
1991
Language:
english
File:
PDF, 156 KB
english, 1991
120

Length of follow-up in randomized clinical trials

Year:
1991
Language:
english
File:
PDF, 79 KB
english, 1991
122

Randomization by cluster: An example from the field of perinatal trials

Year:
1991
Language:
english
File:
PDF, 73 KB
english, 1991
123

How one data coordinating center resolved its computing literacy problems

Year:
1991
Language:
english
File:
PDF, 73 KB
english, 1991
125

Software solutions for management of clinical data—Present and future

Year:
1991
Language:
english
File:
PDF, 68 KB
english, 1991
126

Computer-assisted radiographic digitization in the assessment of total HIP implants

Year:
1991
Language:
english
File:
PDF, 68 KB
english, 1991
127

Statistical analysis of multiple failures in clinical trials for treatment of drug dependence

Year:
1991
Language:
english
File:
PDF, 68 KB
english, 1991
129

Visualization of clinical data with the SAS(R) system

Year:
1991
Language:
english
File:
PDF, 76 KB
english, 1991
130

24-hour blood pressure measurement; methods of analysis and data requirements

Year:
1991
Language:
english
File:
PDF, 147 KB
english, 1991
132

The use of the propensity score in the analysis of clinical trials

Year:
1991
Language:
english
File:
PDF, 72 KB
english, 1991
133

Bayesian analysis of neutron therapy trial

Year:
1991
Language:
english
File:
PDF, 147 KB
english, 1991
135

The analysis of multiple end points with a two-stage group sequential design

Year:
1991
Language:
english
File:
PDF, 77 KB
english, 1991
136

Parallel randomized and nonrandomized clinical trials: What can we gain?

Year:
1991
Language:
english
File:
PDF, 75 KB
english, 1991
138

Interim p-values for group sequentially monitored trials

Year:
1991
Language:
english
File:
PDF, 75 KB
english, 1991
139

Interim monitoring for vaccine efficacy

Year:
1991
Language:
english
File:
PDF, 77 KB
english, 1991
141

Sample size issues for inferences about correlated proportions

Year:
1991
Language:
english
File:
PDF, 77 KB
english, 1991
142

Simulation in clinical trial design

Year:
1991
Language:
english
File:
PDF, 71 KB
english, 1991
143

10.1016/0197-2456(91)90210-d

Year:
1991
Language:
english
File:
PDF, 71 KB
english, 1991
149

Surveillance in medicine

Year:
1991
Language:
english
File:
PDF, 69 KB
english, 1991
150

An illustration of survival analysis: A study of intensive care unit patients

Year:
1991
Language:
english
File:
PDF, 72 KB
english, 1991
151

Risk groups of lung cancer and the model of the people screening

Year:
1991
Language:
english
File:
PDF, 72 KB
english, 1991
152

Application of random effects regression to longitudinal psychiatric data

Year:
1991
Language:
english
File:
PDF, 72 KB
english, 1991
154

Electronic coordinating center—The centralized model

Year:
1991
Language:
english
File:
PDF, 79 KB
english, 1991
155

Intergroup participation—The challenge of multigroup trials

Year:
1991
Language:
english
File:
PDF, 152 KB
english, 1991
161

Applying the ISO/OSI model to distributed data entry systems

Year:
1991
Language:
english
File:
PDF, 69 KB
english, 1991
163

Recruitment of patients into company sponsored clinical trials in Australia

Year:
1991
Language:
english
File:
PDF, 75 KB
english, 1991
166

The perinatal trials service

Year:
1991
Language:
english
File:
PDF, 62 KB
english, 1991
168

Locating patients lost to follow-up in clinical trials

Year:
1991
Language:
english
File:
PDF, 81 KB
english, 1991
169

Comparison of methods for follow-up by mail

Year:
1991
Language:
english
File:
PDF, 81 KB
english, 1991
170

Patient response in a large follow-up by mail

Year:
1991
Language:
english
File:
PDF, 81 KB
english, 1991
174

Management of study proposals: From an idea to a manuscript

Year:
1991
Language:
english
File:
PDF, 79 KB
english, 1991
176

Conducting clinical study of GCP standards in the Soviet union-case analysis

Year:
1991
Language:
english
File:
PDF, 74 KB
english, 1991
179

Closed testing procedures for multiple end-point analysis

Year:
1991
Language:
english
File:
PDF, 70 KB
english, 1991
181

Application of regression tree method as a tool to analyze a clinical trial

Year:
1991
Language:
english
File:
PDF, 70 KB
english, 1991
183

The influence of missing data in the analysis of composite endpoints

Year:
1991
Language:
english
File:
PDF, 76 KB
english, 1991
185

Extended Mantel-Haenszel procedures for analyzing multicenter clinical trials

Year:
1991
Language:
english
File:
PDF, 67 KB
english, 1991
187

Subgroup analyses in clinical trials

Year:
1991
Language:
english
File:
PDF, 128 KB
english, 1991
190

Modifications to point summary odds ratio estimators

Year:
1991
Language:
english
File:
PDF, 75 KB
english, 1991
191

Analysis of recurrent events in superficial bladder cancer

Year:
1991
Language:
english
File:
PDF, 75 KB
english, 1991
192

A general measure of correlation for logistic model

Year:
1991
Language:
english
File:
PDF, 145 KB
english, 1991
193

Robust logistic regression in diagnosis assistance and clinical trials applications

Year:
1991
Language:
english
File:
PDF, 72 KB
english, 1991
195

Intraclass correlation coefficient—methodology and applications

Year:
1991
Language:
english
File:
PDF, 68 KB
english, 1991
197

Data tracking and recording techniques in a multicenter clinical trial

Year:
1991
Language:
english
File:
PDF, 74 KB
english, 1991
201

Computerized management of treatment assignments

Year:
1991
Language:
english
File:
PDF, 77 KB
english, 1991
202

A clinical research management system

Year:
1991
Language:
english
File:
PDF, 60 KB
english, 1991
205

Robust sequential crossover designs for clinical trials

Year:
1991
Language:
english
File:
PDF, 79 KB
english, 1991
206

Determination of sample size taking account of certain prior information

Year:
1991
Language:
english
File:
PDF, 144 KB
english, 1991
207

Cancer prevention trials using micronutrients: Design issues

Year:
1991
Language:
english
File:
PDF, 67 KB
english, 1991
210

Observed versus expected: Verifying clinical impressions in ophthalmologic trials

Year:
1991
Language:
english
File:
PDF, 77 KB
english, 1991
212

Primary prevention trials of cholesterol lowering agents: A tale of three trials

Year:
1991
Language:
english
File:
PDF, 75 KB
english, 1991
214

The Canadian abdominal aortic aneurysm (AAA) treatment trial

Year:
1991
Language:
english
File:
PDF, 76 KB
english, 1991
215

Corneal transplant follow-up study (CTFS)

Year:
1991
Language:
english
File:
PDF, 76 KB
english, 1991
218

Design and analysis considerations in prophylactic studies in recurrent vaginal candidiasis

Year:
1991
Language:
english
File:
PDF, 57 KB
english, 1991
223

Agreement assessment in multicenter clinical trials

Year:
1991
Language:
english
File:
PDF, 143 KB
english, 1991
228

A flaw in the generalized maximum likelihood estimate with a suggested repair

Year:
1991
Language:
english
File:
PDF, 70 KB
english, 1991
230

Two-step procedure for survival analysis

Year:
1991
Language:
english
File:
PDF, 71 KB
english, 1991
235

Data entry training for a small clinical trial

Year:
1991
Language:
english
File:
PDF, 69 KB
english, 1991
239

Improved monitoring of multicenter trials by an extended database

Year:
1991
Language:
english
File:
PDF, 149 KB
english, 1991
242

Management of data files in preparation for statistical analysis

Year:
1991
Language:
english
File:
PDF, 75 KB
english, 1991
243

Towards reducing observer effects in blood pressure (BP) measurement

Year:
1991
Language:
english
File:
PDF, 75 KB
english, 1991
245

Searching for hidden periodicities in biological time series

Year:
1991
Language:
english
File:
PDF, 81 KB
english, 1991
247

The questions we have to answer when using QALYS

Year:
1991
Language:
english
File:
PDF, 76 KB
english, 1991
248

An analysis of methods of communication in clinical trials

Year:
1991
Language:
english
File:
PDF, 76 KB
english, 1991
250

Sources of variation in clinical center workloads during a 15-year period

Year:
1991
Language:
english
File:
PDF, 74 KB
english, 1991
259

Electronic compliance monitoring in clinical trials: Benefits and risks

Year:
1991
Language:
english
File:
PDF, 77 KB
english, 1991
261

Data management concepts at the epidemiology data center

Year:
1991
Language:
english
File:
PDF, 154 KB
english, 1991
262

Early patient accrual for a multicenter clinical trial

Year:
1991
Language:
english
File:
PDF, 79 KB
english, 1991
264

Comparative study of multiple testing procedures in phase II clinical trials

Year:
1991
Language:
english
File:
PDF, 71 KB
english, 1991
268

Guidelines for monitoring company sponsored clinical trials in the pharmaceutical industry

Year:
1991
Language:
english
File:
PDF, 141 KB
english, 1991