Current Opinion in Pharmacology

1

Molecular biology and functional genomics of liver X receptors (LXR) in relationship to metabolic diseases

Malin Hedengran Faulds, Chunyan Zhao, Karin Dahlman-Wright

Journal:

Year:

2010

Language:

english

File:

PDF, 224 KB

english, 2010

2

Wnt and mammary stem cells: hormones cannot fly wingless

Kevin Roarty, Jeffrey M Rosen

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 366 KB

english, 2010

3

Glucocorticoid receptor cofactors as therapeutic targets

S Stoney Simons Jr

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 181 KB

english, 2010

4

Mechanisms of adiponectin regulation and use as a pharmacological target

Susan A Phillips, Jacqueline T Kung

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 237 KB

english, 2010

5

Inflammatory signaling pathways in self-renewing breast cancer stem cells

Kunihiko Hinohara, Noriko Gotoh

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 225 KB

english, 2010

6

Insulin signaling in fatty acid and fat synthesis: a transcriptional perspective

Roger HF Wong, Hei Sook Sul

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 459 KB

english, 2010

7

SnoN in mammalian development, function and diseases

Nadine S Jahchan, Kunxin Luo

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 197 KB

english, 2010

8

Brk/PTK6 signaling in normal and cancer cell models

Julie H Ostrander, Andrea R Daniel, Carol A Lange

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 362 KB

english, 2010

9

Multidirectional interplay between nuclear receptors and microRNAs

Deo Prakash Pandey, Didier Picard

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 228 KB

english, 2010

10

HNF4α — role in drug metabolism and potential drug target?

Wendy W Hwang-Verslues, Frances M Sladek

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 348 KB

english, 2010

11

Regulation of ErbB receptor signalling in cancer cells by microRNA

Andrew Barker, Keith M Giles, Michael R Epis, Priscilla M Zhang, Felicity Kalinowski, Peter J Leedman

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 242 KB

english, 2010

12

Computer-aided drug-discovery techniques that account for receptor flexibility

Jacob D Durrant, J Andrew McCammon

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 131 KB

english, 2010

13

Allostery and population shift in drug discovery

Gozde Kar, Ozlem Keskin, Attila Gursoy, Ruth Nussinov

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 469 KB

english, 2010

14

Coarse-grained models: getting more with less

AJ Rader

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 238 KB

english, 2010

15

The role of conformational ensembles of seven transmembrane receptors in functional selectivity

Nagarajan Vaidehi, Terry Kenakin

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 360 KB

english, 2010

16

Drugs for ‘protein clouds’: targeting intrinsically disordered transcription factors

A Keith Dunker, Vladimir N Uversky

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 292 KB

english, 2010

17

Using NMR to study fast dynamics in proteins: methods and applications

Paul J Sapienza, Andrew L Lee

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 533 KB

english, 2010

18

The molecular mechanisms underlying the pharmacological actions of ER modulators: implications for new drug discovery in breast cancer

Donald P McDonnell, Suzanne E Wardell

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 345 KB

english, 2010

19

Reaching biological timescales with all-atom molecular dynamics simulations

Matthew C Zwier, Lillian T Chong

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 236 KB

english, 2010

20

Regulation of specific target genes and biological responses by estrogen receptor subtype agonists

Dale C Leitman, Sreenivasan Paruthiyil, Omar I Vivar, Elise F Saunier, Candice B Herber, Isaac Cohen, Mary Tagliaferri, Terence P Speed

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 299 KB

english, 2010

21

Erratum to “Development of aptamer therapeutics” [Curr. Opin. Pharmacol. 10 (2010) 557–562]

David HJ Bunka, Olga Platonova, Peter G Stockley

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 148 KB

english, 2010

22

From protein folding to protein function and biomolecular binding by energy landscape theory

Alexander Schug, José N Onuchic

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 431 KB

english, 2010

23

Fluorescence anisotropy and resonance energy transfer: powerful tools for measuring real time protein dynamics in a physiological environment

Christopher M Yengo, Christopher L Berger

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 215 KB

english, 2010

24

Ensemble-based methods for describing protein dynamics

Donald J Jacobs

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 429 KB

english, 2010

25

Protein dynamics: dancing on an ever-changing free energy stage

Dennis R Livesay

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 183 KB

english, 2010

26

Molecular dynamics simulations of protein dynamics and their relevance to drug discovery

Freddie R Salsbury Jr

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 148 KB

english, 2010

27

Unraveling the intricacies of receptor activated cell signaling and transcriptional cascades enhance opportunities to develop new therapeutic targets for endocrine and metabolic diseases

Gary L Firestone

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 122 KB

english, 2010

28

Editorial Board

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 45 KB

english, 2010

29

Next Issue page

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 83 KB

english, 2010

Volume 10; Issue 6

Molecular biology and functional genomics of liver X receptors (LXR) in relationship to metabolic diseases

Wnt and mammary stem cells: hormones cannot fly wingless

Glucocorticoid receptor cofactors as therapeutic targets

Mechanisms of adiponectin regulation and use as a pharmacological target

Inflammatory signaling pathways in self-renewing breast cancer stem cells

Insulin signaling in fatty acid and fat synthesis: a transcriptional perspective

SnoN in mammalian development, function and diseases

Brk/PTK6 signaling in normal and cancer cell models

Multidirectional interplay between nuclear receptors and microRNAs

HNF4α — role in drug metabolism and potential drug target?

Regulation of ErbB receptor signalling in cancer cells by microRNA

Computer-aided drug-discovery techniques that account for receptor flexibility

Allostery and population shift in drug discovery

Coarse-grained models: getting more with less

The role of conformational ensembles of seven transmembrane receptors in functional selectivity

Drugs for ‘protein clouds’: targeting intrinsically disordered transcription factors

Using NMR to study fast dynamics in proteins: methods and applications

The molecular mechanisms underlying the pharmacological actions of ER modulators: implications for new drug discovery in breast cancer

Reaching biological timescales with all-atom molecular dynamics simulations

Regulation of specific target genes and biological responses by estrogen receptor subtype agonists

Erratum to “Development of aptamer therapeutics” [Curr. Opin. Pharmacol. 10 (2010) 557–562]

From protein folding to protein function and biomolecular binding by energy landscape theory

Fluorescence anisotropy and resonance energy transfer: powerful tools for measuring real time protein dynamics in a physiological environment

Ensemble-based methods for describing protein dynamics

Protein dynamics: dancing on an ever-changing free energy stage

Molecular dynamics simulations of protein dynamics and their relevance to drug discovery

Unraveling the intricacies of receptor activated cell signaling and transcriptional cascades enhance opportunities to develop new therapeutic targets for endocrine and metabolic diseases

Editorial Board

Contents

Next Issue page