Current Opinion in Pharmacology

1

Qualitative pharmacology in a quantitative world: diminishing value in the drug discovery process

Michael Williams

Journal:

Year:

2011

Language:

english

File:

PDF, 186 KB

english, 2011

2

Non-invasive imaging in experimental medicine for drug development

Paul M Matthews, Ilan Rabiner, Roger Gunn

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 547 KB

english, 2011

3

Circuits and brain rhythms in schizophrenia: a wealth of convergent targets

Miles A Whittington, Anita K Roopun, Roger D Traub, Ceri H Davies

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 957 KB

english, 2011

4

Quality by Design in lead optimization: a new strategy to address productivity in drug discovery

Tino Rossi, Simone Braggio

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 674 KB

english, 2011

5

Modeling complex neuropsychiatric disorders with human induced pluripotent stem cells

Brian TD Tobe, Evan Y Snyder, Jeffrey S Nye

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 431 KB

english, 2011

6

Scientific process, pharmacology and drug discovery

David G Trist

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 413 KB

english, 2011

7

How technology can aid the pharmacologist in carrying out drug discovery

David G Trist, Ceri H Davies

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 229 KB

english, 2011

8

Assaying dissociable elements of behavioural inhibition and impulsivity: translational utility of animal models

Trevor Humby, Lawrence S Wilkinson

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 299 KB

english, 2011

9

Studying synaptic plasticity in the human brain and opportunities for drug discovery

Pradeep J Nathan, Stuart R Cobb, Bai Lu, Edward T Bullmore, Ceri H Davies

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 590 KB

english, 2011

10

The role of gene expression profiling in drug discovery

Stewart Bates

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 257 KB

english, 2011

11

At least it won’t hurt: the personal risks of antibiotic exposure

Andrew J Stewardson, Benedikt Huttner, Stephan Harbarth

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 483 KB

english, 2011

12

A new evolutionary and pharmacokinetic–pharmacodynamic scenario for rapid emergence of resistance to single and multiple anti-tuberculosis drugs

Jotam G Pasipanodya, Tawanda Gumbo

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 349 KB

english, 2011

13

Dosing of colistin—back to basic PK/PD

Phillip J Bergen, Jian Li, Roger L Nation

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 411 KB

english, 2011

14

Beyond serial passages: new methods for predicting the emergence of resistance to novel antibiotics

José Luis Martínez, Fernando Baquero, Dan I Andersson

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 248 KB

english, 2011

15

Revisiting Beta-lactams – PK/PD improves dosing of old antibiotics

Alasdair MacGowan

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 254 KB

english, 2011

16

Co-resistance: an opportunity for the bacteria and resistance genes

Rafael Cantón, Patricia Ruiz-Garbajosa

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 310 KB

english, 2011

17

Resistance drives antibacterial drug development

Ursula Theuretzbacher

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 324 KB

english, 2011

18

Optimizing dosage to prevent emergence of resistance – lessons from in vitro models

Renu Singh, Vincent H Tam

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 238 KB

english, 2011

19

Assessment of efficacy of antifungals in experimental models of invasive aspergillosis in an era of emerging resistance: the value of real-time quantitative PCR

Seyedmojtaba Seyedmousavi, Willem J.G. Melchers, Paul E. Verweij, Johan W. Mouton

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 292 KB

english, 2011

20

Update on antibacterial and antifungal drugs – can we master the resistance crisis?

Ursula Theuretzbacher, Johan W. Mouton

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 165 KB

english, 2011

21

From genes to therapeutic targets for psychiatric disorders – what to expect?

Pierandrea Muglia

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 243 KB

english, 2011

22

Editorial Board

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 48 KB

english, 2011

23

Next Issue page

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 76 KB

english, 2011

25

Understanding pharmacology in humans: Phase I and Phase II (Data Generation)

Emilio Merlo Pich

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 363 KB

english, 2011

Volume 11; Issue 5

Qualitative pharmacology in a quantitative world: diminishing value in the drug discovery process

Non-invasive imaging in experimental medicine for drug development

Circuits and brain rhythms in schizophrenia: a wealth of convergent targets

Quality by Design in lead optimization: a new strategy to address productivity in drug discovery

Modeling complex neuropsychiatric disorders with human induced pluripotent stem cells

Scientific process, pharmacology and drug discovery

How technology can aid the pharmacologist in carrying out drug discovery

Assaying dissociable elements of behavioural inhibition and impulsivity: translational utility of animal models

Studying synaptic plasticity in the human brain and opportunities for drug discovery

The role of gene expression profiling in drug discovery

At least it won’t hurt: the personal risks of antibiotic exposure

A new evolutionary and pharmacokinetic–pharmacodynamic scenario for rapid emergence of resistance to single and multiple anti-tuberculosis drugs

Dosing of colistin—back to basic PK/PD

Beyond serial passages: new methods for predicting the emergence of resistance to novel antibiotics

Revisiting Beta-lactams – PK/PD improves dosing of old antibiotics

Co-resistance: an opportunity for the bacteria and resistance genes

Resistance drives antibacterial drug development

Optimizing dosage to prevent emergence of resistance – lessons from in vitro models

Assessment of efficacy of antifungals in experimental models of invasive aspergillosis in an era of emerging resistance: the value of real-time quantitative PCR

Update on antibacterial and antifungal drugs – can we master the resistance crisis?

From genes to therapeutic targets for psychiatric disorders – what to expect?

Editorial Board

Contents

Next Issue page

Understanding pharmacology in humans: Phase I and Phase II (Data Generation)