Drug Discovery Today

1

Protein structure prediction and model quality assessment

Andriy Kryshtafovych, Krzysztof Fidelis

Journal:

Year:

2009

Language:

english

File:

PDF, 396 KB

english, 2009

2

The genetics of a pharma merger

Philippe Sanseau, Marie Chabot-Fletcher, Michael J. Browne

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 235 KB

english, 2009

3

Modulating receptor function through RAMPs: can they represent drug targets in themselves?

Patrick M. Sexton, David R. Poyner, John Simms, Arthur Christopoulos, Debbie L. Hay

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 590 KB

english, 2009

4

Early integration of pharmacokinetic and dynamic reasoning is essential for optimal development of lead compounds: strategic considerations

Johan Gabrielsson, Hugues Dolgos, Per-Göran Gillberg, Ulf Bredberg, Bert Benthem, Göran Duker

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 1.76 MB

english, 2009

5

Decision support methods for the detection of adverse events in post-marketing data

M. Hauben, A. Bate

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 974 KB

english, 2009

6

Managing protein flexibility in docking and its applications

Chandrika B-Rao, Jyothi Subramanian, Somesh D. Sharma

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 541 KB

english, 2009

7

Insights into liaison between antiepileptic drugs and bone

Suruchi Khanna, Krishna K. Pillai, Divya Vohora

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 477 KB

english, 2009

8

Molecular perspectives on the non-responder phenomenon

David B. Jackson

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 1.12 MB

english, 2009

9

Clinical and economic impact of the nonresponder phenomenon – implications for systems based discovery

David B. Jackson

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 1.63 MB

english, 2009

10

In silico platform for xenobiotics ADME-T pharmacological properties modeling and prediction. Part I: beyond the reduction of animal model use

Lucie Huynh, Rosalinde Masereeuw, Thomas Friedberg, Magnus Ingelman-Sundberg, Philippe Manivet

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 677 KB

english, 2009

11

Healthy skepticism: assessing realistic model performance

Scott P. Brown, Steven W. Muchmore, Philip J. Hajduk

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 1.40 MB

english, 2009

12

In silico platform for xenobiotics ADME-T pharmacological properties modeling and prediction. Part II: the body in a Hilbertian space

Alexandre Jacob, Jaturong Pratuangdejkul, Sébastien Buffet, Jean-Marie Launay, Philippe Manivet

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 1.79 MB

english, 2009

13

Omic profiling for drug safety assessment: current trends and public–private partnerships

William M. Gallagher, David Tweats, Jochen Koenig

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 644 KB

english, 2009

14

The use of combinatorial chemistry libraries for the discovery of biologically active substances

Paul Edwards

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 65 KB

english, 2009

15

Human Microbiome Project—paving the way to a better understanding of ourselves and our microbes

William W.L. Hsiao, Claire M. Fraser-Liggett

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 112 KB

english, 2009

16

Volume 14; Issue 7-8

Protein structure prediction and model quality assessment

The genetics of a pharma merger

Modulating receptor function through RAMPs: can they represent drug targets in themselves?

Early integration of pharmacokinetic and dynamic reasoning is essential for optimal development of lead compounds: strategic considerations

Decision support methods for the detection of adverse events in post-marketing data

Managing protein flexibility in docking and its applications

Insights into liaison between antiepileptic drugs and bone

Molecular perspectives on the non-responder phenomenon

Clinical and economic impact of the nonresponder phenomenon – implications for systems based discovery

In silico platform for xenobiotics ADME-T pharmacological properties modeling and prediction. Part I: beyond the reduction of animal model use

Healthy skepticism: assessing realistic model performance

In silico platform for xenobiotics ADME-T pharmacological properties modeling and prediction. Part II: the body in a Hilbertian space

Omic profiling for drug safety assessment: current trends and public–private partnerships

The use of combinatorial chemistry libraries for the discovery of biologically active substances

Human Microbiome Project—paving the way to a better understanding of ourselves and our microbes

Contents

Contents