Volume 19; Issue 3

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Drug Discovery Today
Volume 19; Issue 3

Drug Discovery Today

Volume 19; Issue 3

1

Computational proteomics: designing a comprehensive analytical strategy

Goh, Wilson Wen Bin, Wong, Limsoon

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 1.91 MB

english, 2014

2

Adipokines as drug targets in joint and bone disease

Scotece, Morena, Conde, Javier, Vuolteenaho, Katriina, Koskinen, Anna, López, Veronica, Gómez-Reino, Juan, Lago, Francisca, Moilanen, Eeva, Gualillo, Oreste

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 664 KB

english, 2014

3

Targeting the nucleolus for cancer-specific activation of p53

Drygin, Denis, O’Brien, Sean E., Hannan, Ross D., McArthur, Grant A., Von Hoff, Daniel D.

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 423 KB

english, 2014

4

Bearing arms against osteoarthritis and sarcopenia: when cartilage and skeletal muscle find common interest in talking together

De Ceuninck, Frédéric, Fradin, Armel, Pastoureau, Philippe

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 729 KB

english, 2014

5

Drug enterohepatic circulation and disposition: constituents of systems pharmacokinetics

Gao, Yu, Shao, Jingwei, Jiang, Zhou, Chen, Jianzhong, Gu, Songen, Yu, Suhong, Zheng, Ke, Jia, Lee

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 2.37 MB

english, 2014

6

Natural products as lead structures: chemical transformations to create lead-like libraries

Pascolutti, Mauro, Quinn, Ronald J.

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 2.36 MB

english, 2014

7

Protein disulfide isomerase: a promising target for cancer therapy

Xu, Shili, Sankar, Saranya, Neamati, Nouri

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 5.29 MB

english, 2014

8

The conformational musings of a medicinal chemist

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 563 KB

english, 2014

9

Reducing attrition in drug development: smart loading preclinical safety assessment

Roberts, Ruth A., Kavanagh, Stefan L., Mellor, Howard R., Pollard, Christopher E., Robinson, Sally, Platz, Stefan J.

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 335 KB

english, 2014

10

In vitro–in vivo extrapolation of drug-induced proarrhythmia predictions at the population level

Polak, Sebastian, Wiśniowska, Barbara, Fijorek, Kamil, Glinka, Anna, Mendyk, Aleksander

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 367 KB

english, 2014

11

Contents page 2

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 52 KB

english, 2014

12

The utility of biomarkers in CNS drug development

Palmer, Alan M.

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 169 KB

english, 2014

13

Virtual pharmaceutical companies: collaborating flexibly in pharmaceutical development

Forster, Simon P., Stegmaier, Julia, Spycher, Rene, Seeger, Stefan

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 1.34 MB

english, 2014

14

The development speed paradox: can increasing development speed reduce R&D productivity?

Lendrem, Dennis W., Lendrem, B. Clare

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 261 KB

english, 2014

15

Contents page 1

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 207 KB

english, 2014

16

Treating osteoporosis by targeting parathyroid hormone to bone

Ponnapakkam, T., Katikaneni, R., Sakon, J., Stratford, R., Gensure, R.C.

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 856 KB

english, 2014

17

Controlling 2-arachidonoylglycerol metabolism as an anti-inflammatory strategy

Alhouayek, Mireille, Masquelier, Julien, Muccioli, Giulio G.

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 802 KB

english, 2014

18

Can pharmaco-electroencephalography help improve survival of central nervous system drugs in early clinical development?

Wilson, Frederick J., Leiser, Steven C., Ivarsson, Magnus, Christensen, Søren R., Bastlund, Jesper F.

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 410 KB

english, 2014

19

Driving external chemistry optimization via operations management principles

Bi, F. Christopher, Frost, Heather N., Ling, Xiaolan, Perry, David A., Sakata, Sylvie K., Bailey, Simon, Fobian, Yvette M., Sloan, Leslie, Wood, Anthony

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 427 KB

english, 2014

20

Is bisphosphonate therapy compromised by the emergence of adverse bone disorders?

Verron, E., Bouler, J.M.

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 533 KB

english, 2014