Volume 47; Issue 11

Drug Metabolism and Disposition

Volume 47; Issue 11

1

Elucidation of N 1 -methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters

Miyake, Takeshi, Mizuno, Tadahaya, Takehara, Issey, Mochizuki, Tatsuki, Kimura, Miyuki, Matsuki, Shunji, Irie, Shin, Watanabe, Nobuaki, Kato, Yukio, Ieiri, Ichiro, Maeda, Kazuya, Ando, Osamu, Kusuhara

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 954 KB

english, 2019

2

Interindividual Variation in CYP3A Activity Influences Lapatinib Bioactivation

Bissada, Jennifer E., Truong, Vivian, Abouda, Arsany A., Wines, Kahari J., Crouch, Rachel D., Jackson, Klarissa D.

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 1.59 MB

english, 2019

3

Development of a Gold Nanoparticle–Functionalized Surface Plasmon Resonance Assay for the Sensitive Detection of Monoclonal Antibodies and Its Application in Pharmacokinetics

Bai, Haihong, Yuan, Mei, Wang, Xiaojing, Wang, Xinghe, Che, Jinjing

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 369 KB

english, 2019

4

Enhanced and Persistent Inhibition of Organic Cation Transporter 1 Activity by Preincubation of Cyclosporine A

Panfen, Erika, Chen, Weiqi, Zhang, Yueping, Sinz, Michael, Marathe, Punit, Gan, Jinping, Shen, Hong

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 1.32 MB

english, 2019

5

Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability

Martinez, Stephanie E., Shi, Jian, Zhu, Hao-Jie, Perez Jimenez, Tania E., Zhu, Zhaohui, Court, Michael H.

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 1004 KB

english, 2019

6

The Molecular Mechanism Regulating Diurnal Rhythm of Flavin-Containing Monooxygenase 5 in Mouse Liver

Chen, Min, Guan, Baozhang, Xu, Haiman, Yu, Fangjun, Zhang, Tianpeng, Wu, Baojian

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 1.44 MB

english, 2019

7

Systematic Development and Verification of a Physiologically Based Pharmacokinetic Model of Rivaroxaban

Cheong, Eleanor Jing Yi, Teo, Denise Wun Xi, Chua, Denise Xin Yi, Chan, Eric Chun Yong

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 1.62 MB

english, 2019

8

Glutathione Conjugation and Protein Adduction Derived from Oxidative Debromination of Benzbromarone in Mice

Wang, Hui, Wang, Wenbao, Gong, Bowen, Wang, Zedan, Feng, Yukun, Zhang, Weige, Wang, Shaojie, Peng, Ying, Zheng, Jiang

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 1.22 MB

english, 2019

9

Metabolism of Strained Rings: Glutathione S -transferase–Catalyzed Formation of a Glutathione-Conjugated Spiro-azetidine without Prior Bioactivation

Li, Xue-Qing, Grönberg, Gunnar, Bangur, Eva-Henriette, Hayes, Martin A., Castagnoli, Neal, Weidolf, Lars

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 918 KB

english, 2019

10

Kinetic Modeling of Steady-State Situations in Cytochrome P450 Enzyme Reactions

Guengerich, F. Peter

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 822 KB

english, 2019

11

Interindividual Variation in CYP3A Activity Influences Lapatinib Bioactivation

Bissada, Jennifer E., Truong, Vivian, Abouda, Arsany A., Wines, Kahari J., Crouch, Rachel D., Jackson, Klarissa D.

Journal:

Drug Metabolism and Disposition

Year:

2019

File:

PDF, 1.59 MB

2019

12

Investigating the Impact of Albumin on the Liver Uptake of Pitavastatin and Warfarin in Nagase Analbuminemic Rats

Chang, Jae H., Chen, Yi-Chen, Cheong, Jonathan, Jones, Robert S., Pang, Jodie

Journal:

Drug Metabolism and Disposition

Year:

2019

File:

PDF, 544 KB

2019