Volume 18; Issue 6

Drug Metabolism and Pharmacokinetics

Volume 18; Issue 6

1

Estimation of Bioavailability of Salmon Calcitonin from the Hypocalcemic Effect in Rats (I): Pharmacokinetic-Pharmacodynamic Modeling Based on the Endogenous Ca Regulatory System

Miyazaki, Makoto, Nakade, Susumu, Iwanaga, Kazunori, Morimoto, Kazuhiro, Kakemi, Masao

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2003

Language:

english

File:

PDF, 253 KB

english, 2003

2

Decreased Function of Genetic Variants, Pro283Leu and Arg287Gly, in Human Organic Cation Transporter hOCT1

Takeuchi, Ayako, Motohashi, Hideyuki, Okuda, Masahiro, Inui, Ken-ichi

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2003

Language:

english

File:

PDF, 177 KB

english, 2003

3

CYP2D in the Brain

Funae, Yoshihiko, Kishimoto, Wataru, Cho, Toshio, Niwa, Toshiro, Hiroi, Toyoko

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2003

Language:

english

File:

PDF, 321 KB

english, 2003

4

Estimation of Bioavailability of Salmon Calcitonin from the Hypocalcemic Effect in Rats (II): Effect of Protease Inhibitor on the Pharmacokinetic-Pharmacodynamic Relationship after Intranasal Administration

Miyazaki, Makoto, Nakade, Susumu, Iwanaga, Kazunori, Morimoto, Kazuhiro, Kakemi, Masao

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2003

Language:

english

File:

PDF, 208 KB

english, 2003

5

Novel Organic Nitrate Prodrug 4(R)-N-(2-Nitroxyethyl)-2-Oxothiazolidine-4-Carboxamide (RS-7897) Serves as a Xenobiotic Substrate for Pyroglutamyl Aminopeptidase I in Dogs

Abe, Koji, Yamada, Makiko, Terao, Toshio, Mizuno, Hiroshi, Matsuoka, Yuko, Yorikane, Ryosuke, Tokui, Taro, Ikeda, Toshihiko

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2003

Language:

english

File:

PDF, 205 KB

english, 2003

6

Involvement of Multiple Transport Systems in the Disposition of an Active Metabolite of a Prodrugtype New Quinolone Antibiotic, Prulifloxacin

Yagi, Yukihiro, Shibutani, Sachiyo, Hodoshima, Naoko, Ishiwata, Kazuya, Okudaira, Noriko, Li, Qing, Sai, Yoshimichi, Kato, Yukio, Tsuji, Akira

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2003

Language:

english

File:

PDF, 445 KB

english, 2003

7

New SRM Data Dependent Exclusion (MS)n Measurement for Structural Determination of Drug Metabolites Using LC/ESI/Ion Trap MS

Tozuka, Zenzaburo, Kaneko, Hayato, Shiraga, Toshifumi, Beppu, Manabu, Niwa, Toshiro, Kawamura, Akio, Kagayama, Akira

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2003

Language:

english

File:

PDF, 702 KB

english, 2003

8

Comparative Study of Flux of FITC-labeled Dextran 4000 on Normal (iso)- and Hyper-osmolarity in Basal Side in Caco-2 Cell Monolayers

Ohkubo, Rie, Tomita, Mikio, Hotta, Yoshiyuki, Nagira, Mayuko, Hayashi, Masahiro

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2003

Language:

english

File:

PDF, 103 KB

english, 2003

9

Twentysix Novel Single Nucleotide Polymorphisms and their Frequencies of the NR1I3(CAR) Gene in a Japanese Population

Ikeda, Shinobu, Kurose, Kouichi, Ozawa, Shogo, Sai, Kimie, Hasegawa, Ryuichi, Komamura, Kazuo, Ueno, Kazuyuki, Kamakura, Shiro, Kitakaze, Masafumi, Tomoike, Hitonobu, Nakajima, Toshiharu, Matsumoto, K

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2003

Language:

english

File:

PDF, 349 KB

english, 2003

10

The Intestinal First-pass Metabolism of Substrates of CYP3A4 and P-glycoprotei—Quantitative Analysis Based on Information from the Literature

Kato, Motohiro, Chiba, Koji, Hisaka, Akihiro, Ishigami, Michi, Kayama, Makoto, Mizuno, Naomi, Nagata, Yoshinori, Takakuwa, Susumu, Tsukamoto, Yuko, Ueda, Kaoru, Kusuhara, Hiroyuki, Ito, Kiyomi, Sugiya

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2003

Language:

english

File:

PDF, 200 KB

english, 2003

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