Volume 25; Issue 4

Drug Metabolism and Pharmacokinetics

Volume 25; Issue 4

1

Molecular Mechanisms of Biliary Excretion of Cefditoren and the Effects of Cefditoren on the Expression Levels of Hepatic Transporters

Meng, Qiang, Liu, Qi, Wang, Changyuan, Sun, Huijun, Kaku, Taiichi, Kato, Yukio, Liu, Kexin

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 495 KB

english, 2010

2

Human Erythrocyte Nucleoside Transporter ENT1 Functions at Ice-cold Temperatures

Takano, Mikihisa, Kimura, Eri, Suzuki, Satoshi, Nagai, Junya, Yumoto, Ryoko

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 684 KB

english, 2010

3

Comparison of Cytochrome P450 3A Enzymes in Cynomolgus Monkeys and Humans

Iwasaki, Kazuhide, Murayama, Norie, Koizumi, Ryo, Uno, Yasuhiro, Yamazaki, Hiroshi

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 152 KB

english, 2010

4

Kinetics of 6-Thioxanthine Metabolism by Allelic Variants of Xanthine Oxidase

Kudo, Mutsumi, Sasaki, Takamitsu, Ishikawa, Masaaki, Hirasawa, Noriyasu, Hiratsuka, Masahiro

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 334 KB

english, 2010

5

Genetic Variations in UDP-glucuronosyltransferase 2B7 Gene (UGT2B7) in a Korean Population

Hwang, Mi-Sun, Lee, Su-Jun, Jeong, Hye-Eun, Lee, SangSeop, Yoo, Mi-Ae, Shin, Jae-Gook

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 405 KB

english, 2010

6

Six Novel Single Nucleotide Polymorphisms of the Steroid Sulfatase Gene in a Japanese Population

Matsumoto, Jun, Ariyoshi, Noritaka, Ishii, Itsuko, Kitada, Mitsukazu

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 313 KB

english, 2010

7

Effects of CYP2C93 and CYP2C9 13 on Diclofenac Metabolism and Inhibition-based Drug-Drug Interactions

Zi, Jing, Liu, Duan, Ma, Pingping, Huang, He, Zhu, Juanli, Wei, Dongqing, Yang, Jin, Chen, Chao

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 266 KB

english, 2010

8

Elevated Systemic Elimination of Cimetidine in Rats with Acute Biliary Obstruction: The Role of Renal Organic Cation Transporter OCT2

Kurata, Tomohiko, Muraki, Yuichi, Mizutani, Hideki, Iwamoto, Takuya, Okuda, Masahiro

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 347 KB

english, 2010

9

Prediction of Interindividual Variability in Pharmacokinetics for CYP3A4 Substrates in Humans

Kato, Motohiro, Chiba, Koji, Ito, Takashi, Koue, Toshiko, Sugiyama, Yuichi

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 688 KB

english, 2010

10

Consideration of Reliable Concentrations for Prediction of Change in Enzyme Activity by Mechanism-based Inactivation Using Physiologically-based Pharmacokinetic Model Simulations

Sato, Kimihiko, Mizuki, Yasuyuki, Komuro, Setsuko

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 600 KB

english, 2010

11

The Globalization of JSSX DMPK Progress in Research

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 144 KB

english, 2010

12

Increased Expression of Hepatic Organic Cation Transporter 1 and Hepatic Distribution of Metformin in High-fat Diet-induced Obese Mice

Jang, Eun-Hee, Klm, Hyoung-Kwang, Park, Chang-Shin, Kang, Ju-Hee

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 384 KB

english, 2010

13

Deconjugation Kinetics of Glucuronidated Phase II Flavonoid Metabolites by β-glucuronidase from Neutrophils

Bartholomé, Roger, Haenen, Guido, Hollman, Peter C.H., Bast, Aalt, Dagnelie, Pieter C., Roos, Dirk, Keijer, Jaap, Kroon, Paul A., Needs, Paul W., Arts, Ilja C.W.

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 312 KB

english, 2010