Volume 28; Issue 3

Drug Metabolism and Pharmacokinetics

Volume 28; Issue 3

1

Rapid Stimulating Effect of the Antiarrhythmic Agent Amiodarone on Absorption of Organic Anion Compounds

Segawa, Masahiro, Ogura, Jiro, Seki, Satoru, Itagaki, Shirou, Takahashi, Natsuko, Kobayashi, Masaki, Hirano, Takeshi, Yamaguchi, Hiroaki, Iseki, Ken

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 1.11 MB

english, 2013

2

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of Empagliflozin, a Sodium Glucose Cotransporter 2 (SGLT2) Inhibitor, in Healthy Japanese Subjects

Sarashina, Akiko, Koiwai, Kazuki, Seman, Leo J., Yamamura, Norio, Taniguchi, Atsushi, Negishi, Takahiro, Sesoko, Shogo, Woerle, Hans J., Dugi, Klaus A.

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 946 KB

english, 2013

3

Mechanism-based Inhibition of CYP1A1 and CYP3A4 by the Furanocoumarin Chalepensin

Ueng, Yune-Fang, Chen, Chien-Chih, Yamazaki, Hiroshi, Kiyotani, Kazuma, Chang, Yu-Ping, Lo, Wei-Shang, Li, Ding-Tzai, Tsai, Pei-Lun

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 1.44 MB

english, 2013

4

Comparison of Serotonin Glucuronidation Activity of UDP-glucuronosyltransferase 1a6a (Ugt1a6a) and Ugt1a6b: Evidence for the Preferential Expression of Ugt1a6a in the Mouse Brain

Uchihashi, Shinsuke, Nishikawa, Miyu, Sakaki, Toshiyuki, Ikushiro, Shin-ichi

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 471 KB

english, 2013

5

Genetic Variations of NR2A1 in Asian Populations: Implications in Pharmacogenetics Studies

Chew, Sin Chi, Lim, Joanne Siok Liu, Lee, Edmund J.D., Chowbay, Balram

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 824 KB

english, 2013

6

Cost-effectiveness Analysis of Microdose Clinical Trials in Drug Development

Yamane, Naoe, Igarashi, Ataru, Kusama, Makiko, Maeda, Kazuya, Ikeda, Toshihiko, Sugiyama, Yuichi

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 334 KB

english, 2013

7

Effects of Green Tea Catechins on Cytochrome P450 2B6, 2C8, 2C19, 2D6 and 3A Activities in Human Liver and Intestinal Microsomes

Misaka, Shingen, Kawabe, Keisuke, Onoue, Satomi, Werba, José Pablo, Giroli, Monica, Tamaki, Sekihiro, Kan, Toshiyuki, Kimura, Junko, Watanabe, Hiroshi, Yamada, Shizuo

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 541 KB

english, 2013

8

Strain Difference of Oxidative Metabolism of the Sedative-hypnotic Zaleplon by Aldehyde Oxidase and Cytochrome P450 In Vivo and In Vitro in Rats

Tanoue, Chiaki, Sugihara, Kazumi, Uramaru, Naoto, Watanabe, Yoko, Tayama, Yoshitaka, Ohta, Shigeru, Kitamura, Shigeyuki

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 762 KB

english, 2013

9

Cytotoxic Effects of Benzbromarone and Its 1′-Hydroxy Metabolite in Human Hepatocarcinoma FLC4 Cells Cultured on Micro-space Cell Culture Plates

Kobayashi, Kaoru, Kajiwara, Eri, Ishikawa, Masayuki, Mimura, Hanaka, Oka, Hidenobu, Ejiri, Yoko, Hosoda, Masaya, Chiba, Kan

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 367 KB

english, 2013

10

Population Pharmacokinetics and Exposure–response Relationship of a Muscarinic Receptor Antagonist, Imidafenacin

Hasegawa, Chihiro, Ohno, Tomoya, Nakade, Susumu, Shibakawa, Kimio, Miyabe, Hiroyuki, Ouchi, Takafumi, Ogawa, Mikio

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 2.16 MB

english, 2013

11

Impact of ABCC2, ABCG2 and SLCO1B1 Polymorphisms on the Pharmacokinetics of Pitavastatin in Humans

Oh, Eun Sil, Kim, Choon Ok, Cho, Sung Kweon, Park, Min Soo, Chung, Jae-Yong

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 319 KB

english, 2013

12

The Influence of UGT2B7, UGT1A8, MDR1, ALDH, ADH, CYP3A4 and CYP3A5 Genetic Polymorphisms on the Pharmacokinetics of Silodosin in Healthy Chinese Volunteers

Wang, Zining, Xiang, Qian, Cui, Yimin, Zhao, Xia, Zhou, Ying

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 223 KB

english, 2013

13

Competitive Inhibition of Human Organic Anion Transporters 1 (SLC22A6), 3 (SLC22A8) and 4 (SLC22A11) by Major Components of the Medicinal Herb Salvia miltiorrhiza (Danshen)

Wang, Li, Sweet, Douglas H.

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 1.39 MB

english, 2013

14

Hepatocyte Nuclear Factor 6 Activates the Transcription of CYP3A4 in Hepatocyte-like Cells Differentiated from Human Induced Pluripotent Stem Cells

Sasaki, Takamitsu, Takahashi, Shogo, Numata, Yoshihiro, Narita, Masayo, Tanaka, Yutaka, Kumagai, Takeshi, Kondo, Yuki, Matsunaga, Tamihide, Ohmori, Shigeru, Nagata, Kiyoshi

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 2.54 MB

english, 2013

15

Influence of SLCO1B3 Genetic Variations on Tacrolimus Pharmacokinetics in Renal Transplant Recipients

Boivin, Andrée-Anne, Cardinal, Héloïse, Barama, Azemi, Naud, Judith, Pichette, Vincent, Hébert, Marie-Josée, Roger, Michel

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 127 KB

english, 2013

16

The JSSX Annual Meeting: Today and the Future

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 39 KB

english, 2013