Volume 29; Issue 6

Drug Metabolism and Pharmacokinetics

Volume 29; Issue 6

1

Inhibitory Effects of Calf Thymus DNA on Metabolism Activity of CYP450 Enzyme in Human Liver Microsomes

Yang, Shuoye, Qiu, Zhixia, Zhang, Qiuyang, Chen, Jiayin, Chen, Xijing

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 938 KB

english, 2014

2

Three Dimensional In Vitro Human Tissue Models for ADME-Tox Studies

Chun, Young-Jin

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 53 KB

english, 2014

3

Human Nitrilase-like Protein Does Not Catalyze the Hydrolysis of Vildagliptin

Asakura, Mitsutoshi, Nakano, Masataka, Hayashida, Kohei, Fujii, Hideaki, Nakajima, Miki, Atsuda, Koichiro, Itoh, Tomoo, Fujiwara, Ryoichi

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 882 KB

english, 2014

4

Evaluation of a Thiodipeptide, l-Phenylalanyl-Ψ[CS-N]-l-alanine, as a Novel Probe for Peptide Transporter 1

Arakawa, Hiroshi, Saito, Sachi, Kanagawa, Masahiko, Kamioka, Hiroki, Yano, Kentaro, Morimoto, Kaori, Ogihara, Takuo

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 578 KB

english, 2014

5

Population Pharmacokinetic and Pharmacodynamic Analysis of Bosutinib

Hsyu, Poe-Hirr, Mould, Diane R., Abbas, Richat, Amantea, Michael

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 1.74 MB

english, 2014

6

A Proposal of a Pharmacokinetic/pharmacodynamic (PK/PD) Index Map for Selecting an Optimal PK/PD Index from Conventional Indices (AUC/MIC, Cmax/MIC, and TAM) for Antibiotics

Kitamura, Yoshiaki, Yoshida, Kenta, Kusama, Makiko, Sugiyama, Yuichi

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 567 KB

english, 2014

7

CYP-dependent Metabolism of Antitumor Pyrazolo[3,4-d]pyrimidine Derivatives Is Characterized by an Oxidative Dechlorination Reaction

Zamperini, Claudio, Dreassi, Elena, Vignaroli, Giulia, Radi, Marco, Dragoni, Stefania, Schenone, Silvia, Musumeci, Francesca, Valoti, Massimo, Antiochia, Riccarda, Botta, Maurizio

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 934 KB

english, 2014

8

Involvement of Moesin in the Development of Morphine Analgesic Tolerance through P-glycoprotein at the Blood-Brain Barrier

Kobori, Takuro, Fujiwara, Shuhei, Miyagi, Kei, Harada, Shinichi, Nakamoto, Kazuo, Nakagawa, Takayuki, Takahashi, Hideo, Narita, Minoru, Tokuyama, Shogo

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 1.28 MB

english, 2014

9

Ethnic Differences in ATP-binding Cassette Transporter, Sub-family G, Member 2 (ABCG2/BCRP): Genotype Combinations and Estimated Functions

Sakiyama, Masayuki, Matsuo, Hirotaka, Takada, Yuzo, Nakamura, Takahiro, Nakayama, Akiyoshi, Takada, Tappei, Kitajiri, Shin-ichiro, Wakai, Kenji, Suzuki, Hiroshi, Shinomiya, Nariyoshi

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 117 KB

english, 2014

10

Influence of UGT1A1 6, 27, and *28 Polymorphisms on Nilotinib-induced Hyperbilirubinemia in Japanese Patients with Chronic Myeloid Leukemia

Abumiya, Maiko, Takahashi, Naoto, Niioka, Takenori, Kameoka, Yoshihiro, Fujishima, Naohito, Tagawa, Hiroyuki, Sawada, Kenichi, Miura, Masatomo

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 531 KB

english, 2014