Volume 39; Issue 1

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Drug Metabolism Reviews
Volume 39; Issue 1

Drug Metabolism Reviews

Volume 39; Issue 1

1

Genomic Structure and Transcriptional Regulation of the Rat, Mouse, and Human Carboxylesterase Genes

Hosokawa, Masakiyo, Furihata, Tomomi, Yaginuma, Yumiko, Yamamoto, Naoko, Koyano, Nao, Fujii, Ayako, Nagahara, Yuko, Satoh, Testuo, Chiba, Kan

Journal:

Drug Metabolism Reviews

Year:

2007

Language:

english

File:

PDF, 286 KB

english, 2007

2

State-of-the-art Tools for Computational Site of Metabolism Predictions: Comparative Analysis, Mechanistical Insights, and Future Applications

Afzelius, Lovisa, Hasselgren Arnby, Catrin, Broo, Anders, Carlsson, Lars, Isaksson, Christine, Jurva, Ulrik, Kjellander, Britta, Kolmodin, Karin, Nilsson, Kristina, Raubacher, Florian, Weidolf, Lars

Journal:

Drug Metabolism Reviews

Year:

2007

Language:

english

File:

PDF, 1.71 MB

english, 2007

3

Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies

Hewitt, Nicola J., Gómez Lechón, María José, Houston, J. Brian, Hallifax, David, Brown, Hayley S., Maurel, Patrick, Kenna, J. Gerald, Gustavsson, Lena, Lohmann, Christina, Skonberg, Christian, Guillou

Journal:

Drug Metabolism Reviews

Year:

2007

Language:

english

File:

PDF, 1.35 MB

english, 2007

4

Pharmacogenetic Screening of the Gene Deletion and Duplications of CYP2D6*

Meijerman, Irma, Sanderson, Linda M., Smits, Paul H.M., Beijnen, Jos H., Schellens, Jan H.M.

Journal:

Drug Metabolism Reviews

Year:

2007

Language:

english

File:

PDF, 263 KB

english, 2007

5

Application of Chimeric Mice with Humanized Liver for Predictive ADME

Katoh, Miki, Yokoi, Tsuyoshi

Journal:

Drug Metabolism Reviews

Year:

2007

Language:

english

File:

PDF, 217 KB

english, 2007

6

What is the Objective of the Mass Balance Study? A Retrospective Analysis of Data in Animal and Human Excretion Studies Employing Radiolabeled Drugs

Roffey, Sarah J., Obach, R. Scott, Gedge, Jenny I., Smith, Dennis A.

Journal:

Drug Metabolism Reviews

Year:

2007

Language:

english

File:

PDF, 225 KB

english, 2007

7

The Antioxidant/electrophile Response Element Motif

Nerland, Donald E.

Journal:

Drug Metabolism Reviews

Year:

2007

Language:

english

File:

PDF, 144 KB

english, 2007

8

Addendum

Journal:

Drug Metabolism Reviews

Year:

2007

File:

PDF, 19 KB

2007

9

Carbonyl Reductases and Pluripotent Hydroxysteroid Dehydrogenases of the Short-chain Dehydrogenase/reductase Superfamily

Hoffmann, Frank, Maser, Edmund

Journal:

Drug Metabolism Reviews

Year:

2007

Language:

english

File:

PDF, 844 KB

english, 2007

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