Volume 16; Issue 2

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Drugs in R & D
Volume 16; Issue 2

Drugs in R & D

Volume 16; Issue 2

1

Safety, Tolerability and Pharmacokinetics of FAAH Inhibitor V158866: A Double-Blind, Randomised, Placebo-Controlled Phase I Study in Healthy Volunteers

Pawsey, Stephen, Wood, Mike, Browne, Helen, Donaldson, Kirsteen, Christie, Mark, Warrington, Steven

Journal:

Year:

2016

Language:

english

File:

PDF, 870 KB

english, 2016

2

Dual Bronchodilator Therapy with Umeclidinium/Vilanterol Versus Tiotropium plus Indacaterol in Chronic Obstructive Pulmonary Disease: A Randomized Controlled Trial

Kalberg, Chris, O’Dell, Dianne, Galkin, Dmitry, Newlands, Amy, Fahy, William A.

Journal:

Year:

2016

Language:

english

File:

PDF, 556 KB

english, 2016

3

Randomized Comparative Bioavailability of a Novel Three-Dimensional Printed Fast-Melt Formulation of Levetiracetam Following the Administration of a Single 1000-mg Dose to Healthy Human Volunteers Under Fasting and Fed Conditions

Boudriau, Sophie, Hanzel, Cecilia, Massicotte, Julie, Sayegh, Laura, Wang, Jing, Lefebvre, Marc

Journal:

Year:

2016

Language:

english

File:

PDF, 614 KB

english, 2016

4

Efficacy and Safety Profile of Diclofenac/Cyclodextrin and Progesterone/Cyclodextrin Formulations: A Review of the Literature Data

Scavone, Cristina, Bonagura, Angela Colomba, Fiorentino, Sonia, Cimmaruta, Daniela, Cenami, Rosina, Torella, Marco, Fossati, Tiziano, Rossi, Francesco

Journal:

Year:

2016

Language:

english

File:

PDF, 762 KB

english, 2016

5

A Multinational, Randomized, Open-label, Treat-to-Target Trial Comparing Insulin Degludec and Insulin Glargine in Insulin-Naïve Patients with Type 2 Diabetes Mellitus

Pan, Changyu, Gross, Jorge L., Yang, Wenying, Lv, Xiaofeng, Sun, Li, Hansen, Charlotte Thim, Xu, Hongfei, Wagner, Robert

Journal:

Year:

2016

Language:

english

File:

PDF, 893 KB

english, 2016

6

Dabigatran Versus Warfarin After Bioprosthesis Valve Replacement for the Management of Atrial Fibrillation Postoperatively: DAWA Pilot Study

Durães, André Rodrigues, de Souza Roriz, Pollianna, de Almeida Nunes, Bianca, Albuquerque, Felipe Pinho e, de Bulhões, Fábio Vieira, de Souza Fernandes, Andre Mauricio, Aras, Roque

Journal:

Year:

2016

Language:

english

File:

PDF, 403 KB

english, 2016

7

Pharmacokinetic Interaction of Rifampicin with Oral Versus Intravenous Anticancer Drugs: Challenges, Dilemmas and Paradoxical Effects Due to Multiple Mechanisms

Srinivas, Nuggehally R.

Journal:

Year:

2016

Language:

english

File:

PDF, 494 KB

english, 2016

8

Population Pharmacokinetic Modelling of FE 999049, a Recombinant Human Follicle-Stimulating Hormone, in Healthy Women After Single Ascending Doses

Rose, Trine Høyer, Röshammar, Daniel, Erichsen, Lars, Grundemar, Lars, Ottesen, Johnny T.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

9

Investigation of Metabolite Profile of YM758, a Novel If Channel Inhibitor

Nakada, Naoyuki

Journal:

Year:

2016

Language:

english

File:

PDF, 1.06 MB

english, 2016

10

Characterisation of Population Pharmacokinetics and Endogenous Follicle-Stimulating Hormone (FSH) Levels After Multiple Dosing of a Recombinant Human FSH (FE 999049) in Healthy Women

Rose, Trine Høyer, Röshammar, Daniel, Erichsen, Lars, Grundemar, Lars, Ottesen, Johnny T.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.27 MB

english, 2016

11

Significant Pharmacokinetic Interactions Between Quinine and Ampicillin–Cloxacillin Combination

Falade, Olubunmi B., Falusi, Adeyinka G., Olaniyi, Ajibola A., Ezeasor, Chizoba, Kwasi, David A., Babalola, Chinedum P.

Journal:

Year:

2016

Language:

english

File:

PDF, 633 KB

english, 2016

12

Cytotoxicity of Oxycodone and Morphine in Human Neuroblastoma and Mouse Motoneuronal Cells: A Comparative Approach

Kokki, Merja, Pesonen, Maija, Vehviläinen, Piia, Litmala, Outi, Pasanen, Markku, Kokki, Hannu

Journal:

Year:

2016

Language:

english

File:

PDF, 1.51 MB

english, 2016