Volume 98

Environmental Health Perspectives

Volume 98

1

Preface

Helmut Bartsch, Ian O'Neill and Fred Kadlubar

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 118 KB

english, 1992

2

Perinatal and Multigenerational Effect of Carcinogens: Possible Contribution to Determination of Cancer Susceptibility

Hiroshi Yamasaki, Alexandre Loktionov and Lorenzo Tomatis

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 231 KB

english, 1992

3

The Debrisoquine Metabolic Phenotype and DNA-Based Assays: Implications of Misclassification for the Association of Lung Cancer and the Debrisoquine Metabolic Phenotype

N. E. Caporaso, P. G. Shields, M. T. Landi, G. L. Shaw, M. A. Tucker, R. Hoover, H. Sugimura, A. Weston and C. C. Harris

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 233 KB

english, 1992

4

Integrated Approach for Evaluating Species and Interindividual Differences in Responsiveness to Dioxins and Structural Analogs

George Clark, Angelika Tritscher, Douglas Bell and George Lucier

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 531 KB

english, 1992

5

Immunohistochemical Detection of Pulmonary Cytochrome P450IA and Metabolic Activities Associated with P450IA1 and P450IA2 Isozymes in Lung Cancer Patients

Sisko Anttila, Harri Vainio, Eino Hietanen, Anne-Marie Camus, Christian Malaveille, Gisele Brun, Kirsti Husgafvel-Pursiainen, Lasse Heikkilä, Antti Karjalainen and Helmut Bartsch

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 548 KB

english, 1992

6

Detection of ras Gene Mutations in Human Lung Cancer: Comparison of Two Screening Assays Based on the Polymerase Chain Reaction

Kirsti Husgafvel-Pursiainen, Maaret Ridanpää, Peter Hackman, Sisko Anttila, Antti Karjalainen, Agneta Önfelt, Anne-Lise Børresen and Harri Vainio

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 423 KB

english, 1992

7

Meeting Report: The Third United States-Japan Meeting on the Toxicological Characterization of Environmental Chemicals

Yuji Kurokawa and Terri Damstra

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 281 KB

english, 1992

8

Front Matter

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 317 KB

english, 1992

9

Multiple Genetic Alterations in Human Carcinogenesis

Takashi Sugimura, Masaaki Terada, Jun Yokota, Setsuo Hirohashi and Keiji Wakabayashi

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 354 KB

english, 1992

10

Role of Proto-Oncogene Activation in Carcinogenesis

Marshall W. Anderson, Steven H. Reynolds, Ming You and Robert M. Maronpot

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 507 KB

english, 1992

11

Tumor-Suppressor Genes: Cardinal Factors in Inherited Predisposition to Human Cancers

H. John Evans and Jane Prosser

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 555 KB

english, 1992

12

Intragenomic Repair Heterogeneity of DNA Damage

David A. Scicchitano and Philip C. Hanawalt

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 310 KB

english, 1992

13

Cisplatin-DNA Damage and Repair in Peripheral Blood Leukocytes in Vivo and in Vitro

Meenakshi Dabholkar, Lita Bradshaw, Ricardo J. Parker, Indrani Gill, Frieda Bostick-Bruton, Franco M. Muggia and Eddie Reed

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 398 KB

english, 1992

14

Relationship of H-ras-1, L-myc, and p53 Polymorphisms with Lung Cancer Risk and Prognosis

Ainsley Weston, Neil E. Caporaso, Laurie S. Perrin, Haruhiko Sugimura, Seiichi Tamai, Theodore G. Krontiris, Benjamin F. Trump, Robert N. Hoover and Curtis C. Harris

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 508 KB

english, 1992

15

Polymorphisms for Aromatic Amine Metabolism in Humans: Relevance for Human Carcinogenesis

Fred F. Kadlubar, Mary Ann Butler, Keith R. Kaderlik, Hsien-Chang Chou and Nicholas P. Lang

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 301 KB

english, 1992

16

Elucidation of Catalytic Specificities of Human Cytochrome P450 and Glutathione S-Transferase Enzymes and Relevance to Molecular Epidemiology

F. Peter Guengerich, Tsutomu Shimada, Kevin D. Raney, Chul-Ho Yun, David J. Meyer, Brian Ketterer, Thomas M. Harris, John D. Groopman and Fred F. Kadlubar

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 275 KB

english, 1992

17

Human Cytochromes P450: Evolution and cDNA-Directed Expression

Frank J. Gonzalez and Harry V. Gelboin

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 247 KB

english, 1992

18

The Human Glutathione S-Transferase Supergene Family, Its Polymorphism, and Its Effects on Susceptibility to Lung Cancer

Brian Ketterer, Jonathan M. Harris, Glen Talaska, David J. Meyer, Sally E. Pemble, John B. Taylor, Nicholas P. Lang and Fred F. Kadlubar

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 347 KB

english, 1992

19

Interindividual Variation in Carcinogen Metabolism and Bladder Cancer Risk

Paolo Vineis and Guglielmo Ronco

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 229 KB

english, 1992

20

Molecular Genetic Analysis of the Cytochrome P450-Debrisoquine Hydroxylase Locus and Association with Cancer Susceptibility

C. A. Dale Smith, Julie E. Moss, Alan C. Gough, Nigel K. Spurr and C. Roland Wolf

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 286 KB

english, 1992

21

Genetic Monitoring of Human Polymorphic Cancer Susceptibility Genes by Polymerase Chain Reaction: Application to Glutathione Transferase μ

Douglas A. Bell, Claudia L. Thompson, Jack Taylor, Chris R. Miller, Frederica Perera, Ling L. Hsieh and George W. Lucier

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 512 KB

english, 1992

22

Carcinogen Metabolism in Human Lung Tissues and the Effect of Tobacco Smoking: Results from a Case-Control Multicenter Study on Lung Cancer Patients

Helmut Bartsch, Stefano Petruzzelli, Silvio De Flora, Eino Hietanen, Anne-Marie Camus, Marcel Castegnaro, Kroum Alexandrov, Margarita Rojas, Rodolfo Saracci and Carlo Giuntini

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 313 KB

english, 1992

23

DNA Adducts and Related Biomarkers in Populations Exposed to Environmental Carcinogens

Frederica Perera, Diane Brenner, Alan Jeffrey, Jack Mayer, Deliang Tang, Dorothy Warburton, Tie-Ian Young, Leila Wazneh, Louise Latriano, Grazyna Motykiewicz, Ewa Grzybowska, Mieczyslaw Chorazy, Kari

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 257 KB

english, 1992

24

Commentary: Application of Biomarkers to Risk Assessment

David W. Gaylor, Fred F. Kadlubar and Frederick A. Beland

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 163 KB

english, 1992

25

Commentary: Biomarkers in Epidemiology: Scientific Issues and Ethical Implications

Paul A. Schulte

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 254 KB

english, 1992

26

Commentary: Biomarkers in Occupational Cancer Epidemiology: Considerations in Study Design

Richard B. Hayes

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 275 KB

english, 1992

27

Contributions from Molecular/Biochemical Approaches in Epidemiology to Cancer Risk Assessment and Prevention

P. H. M. Lohman, B. Morolli, F. Darroudi, A. T. Natarajan, J. A. Gossen, J. Venema, L. H. F. Mullenders, E. W. Vogel, H. Vrieling and A. A. van Zeeland

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 958 KB

english, 1992

28

Allele Diversity of the H-ras-1 Variable Number of Tandem Repeats in Norwegian Lung Cancer Patients

David Ryberg, Toril Tefre, Vidar Skaug, Lodve Stangeland, Steinar Øvrebø, Anne Naalsund, Anne-Lise Børresen and Aage Haugen

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 156 KB

english, 1992

29

Polycyclic Aromatic Hydrocarbon-DNA Adducts and the CYP1A1 Restriction Fragment Length Polymorphism

Peter G. Shields, Haruhiko Sugimura, Neil E. Caporaso, Stefano F. Petruzzelli, Elise D. Bowman, Benjamin F. Trump, Ainsley Weston and Curtis C. Harris

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 533 KB

english, 1992

30

Aberrant Crypt Foci and Microadenoma As Markers for Colon Cancer

Michael C. Archer, W. Robert Bruce, Chung Chow Chan, Denis E. Corpet, Alan Medline, Luca Roncucci, Dennis Stamp and Xue-Ming Zhang

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 981 KB

english, 1992

31

Use of Breath Hydrogen and Methane as Markers of Colonic Fermentation in Epidemiologic Studies: Circadian Patterns of Excretion

Loïc Le Marchand, Lynne R. Wilkens, Patricia Harwood and Robert V. Cooney

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 201 KB

english, 1992

32

Role of Lime in the Generation of Reactive Oxygen Species from Betel-Quid Ingredients

Urmila J. Nair, Günter Obe, Marlin Friesen, Mark T. Goldberg and Helmut Bartsch

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 186 KB

english, 1992

33

Cross-Sectional Study with Multiple Measurements of Biological Markers for Assessing Stomach Cancer Risks at the Population Level

Shcoichiro Tsugane, Mitsuhiro Tsuda, Fred Gey and Shaw Watanabe

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 219 KB

english, 1992

34

Determination of Point Mutational Spectra of Benzo[a]pyrene-diol Epoxide in Human Cells

Phouthone Keohavong and William G. Thilly

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 908 KB

english, 1992

35

Commentary: Nongenotoxic Carcinogens: An Extension of the Perspective Provided by Perera

J. Ashby and I. F. H. Purchase

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 223 KB

english, 1992

36

Development of Source Testing, Analytical, and Mutagenicity Bioassay Procedures for Evaluating Emissions from Municipal and Hospital Waste Combustors

Randall R. Watts, Paul M. Lemieux, Raymond A. Grote, R. William Lowans, Ron W. Williams, Lance R. Brooks, Sarah H. Warren, David M. DeMarini, Douglas A. Bell and Joellen Lewtas

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 336 KB

english, 1992

37

EPA Priorities for Biologic Markers Research in Environmental Health

John R. Fowle, III and Ken Sexton

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 289 KB

english, 1992

38

The Findings of the Agency for Toxic Substances and Disease Registry Medical Waste Tracking Act Report

Maureen Y. Lichtveld, Sven E. Rodenbeck and Jeffrey A. Lybarger

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 340 KB

english, 1992

39

Determinants of Serum Zinc in a Random Population Sample of Four Belgian Towns with Different Degrees of Environmental Exposure to Cadmium

Lutgarde Thijs, Jan Staessen, Antoon Amery, Pierre Bruaux, Jean-Pierre Buchet, Françoise Claeys, Pierre De Plaen, Geneviève Ducoffre, Robert Lauwerys, Paul Lijnen, Laurence Nick, Annie Saint Remy, Har

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 343 KB

english, 1992

40

Toxicity of Vesicant Agents Scheduled for Destruction by the Chemical Stockpile Disposal Program

A. P. Watson and G. D. Griffin

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 793 KB

english, 1992

41

Back Matter

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 182 KB

english, 1992

42

Molecular Epidemiology in Cancer Risk Assessment and Prevention: Recent Progress and Avenues for Future Research

Gerald N. Wogan

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 724 KB

english, 1992

43

Biomarkers for Individual Susceptibility to Carcinogenic Agents: Excretion and Carcinogenic Risk of Benzo[a]pyrene Metabolites

Alexei J. Likhachev, Dzamal Sh. Beniashvili, Vladimir J. Bykov, Pavel P. Dikun, Margarita L. Tyndyk, Irina V. Savochkina, Vladimir B. Yermilov and Mark A. Zabezhinski

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 224 KB

english, 1992

44

Role of proto-oncogene activation in carcinogenesis.

Anderson, M W, Reynolds, S H, You, M, Maronpot, R M

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 2.85 MB

english, 1992

45

Detection of ras gene mutations in human lung cancer: comparison of two screening assays based on the polymerase chain reaction.

Husgafvel-Pursiainen, K, Ridanpää, M, Hackman, P, Anttila, S, Karjalainen, A, Onfelt, A, Børresen, A L, Vainio, H

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 885 KB

english, 1992

46

The debrisoquine metabolic phenotype and DNA-based assays: implications of misclassification for the association of lung cancer and the debrisoquine metabolic phenotype.

Caporaso, N E, Shields, P G, Landi, M T, Shaw, G L, Tucker, M A, Hoover, R, Sugimura, H, Weston, A, Harris, C C

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 990 KB

english, 1992

47

Preface

Bartsch, Helmut, O'Neill, Ian, Kadlubar, Fred

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 216 KB

english, 1992

48

Relationship of H-ras-1, L-myc, and p53 polymorphisms with lung cancer risk and prognosis.

Weston, A, Caporaso, N E, Perrin, L S, Sugimura, H, Tamai, S, Krontiris, T G, Trump, B F, Hoover, R N, Harris, C C

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 1.49 MB

english, 1992

49

Allele diversity of the H-ras-1 variable number of tandem repeats in Norwegian lung cancer patients.

Ryberg, D, Tefre, T, Skaug, V, Stangeland, L, Ovrebø, S, Naalsund, A, Børresen, A L, Haugen, A

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 395 KB

english, 1992

50

Human cytochromes P450: evolution and cDNA-directed expression.

Gonzalez, F J, Gelboin, H V

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 1.02 MB

english, 1992

51

Determination of point mutational spectra of benzo[a]pyrene-diol epoxide in human cells.

Keohavong, P, Thilly, W G

Journal:

Environmental Health Perspectives

Year:

1992

File:

PDF, 1.55 MB

1992

52

Carcinogen metabolism in human lung tissues and the effect of tobacco smoking: results from a case--control multicenter study on lung cancer patients.

Bartsch, H, Petruzzelli, S, De Flora, S, Hietanen, E, Camus, A M, Castegnaro, M, Alexandrov, K, Rojas, M, Saracci, R, Giuntini, C

Journal:

Environmental Health Perspectives

Year:

1992

File:

PDF, 1.38 MB

1992

53

Genetic monitoring of human polymorphic cancer susceptibility genes by polymerase chain reaction: application to glutathione transferase mu.

Bell, D A, Thompson, C L, Taylor, J, Miller, C R, Perera, F, Hsieh, L L, Lucier, G W

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 1.14 MB

english, 1992

54

Biomarkers in epidemiology: scientific issues and ethical implications.

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 1.08 MB

english, 1992

55

Polycyclic aromatic hydrocarbon-DNA adducts and the CYP1A1 restriction fragment length polymorphism.

Shields, P G, Sugimura, H, Caporaso, N E, Petruzzelli, S F, Bowman, E D, Trump, B F, Weston, A, Harris, C C

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 909 KB

english, 1992

56

Aberrant crypt foci and microadenoma as markers for colon cancer.

Archer, M C, Bruce, W R, Chan, C C, Corpet, D E, Medline, A, Roncucci, L, Stamp, D, Zhang, X M

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 1.32 MB

english, 1992

57

Tumor-suppressor genes: cardinal factors in inherited predisposition to human cancers.

Evans, H J, Prosser, J

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 3.10 MB

english, 1992

58

Carcinogen metabolism in human lung tissues and the effect of tobacco smoking: results from a case--control multicenter study on lung cancer patients.

Bartsch, H, Petruzzelli, S, De Flora, S, Hietanen, E, Camus, A M, Castegnaro, M, Alexandrov, K, Rojas, M, Saracci, R, Giuntini, C

Journal:

Environmental Health Perspectives

Year:

1992

Language:

english

File:

PDF, 1.38 MB

english, 1992

59

Application of biomarkers to risk assessment.

Gaylor, D W, Kadlubar, F F, Beland, F A

Journal:

Environmental Health Perspectives

Year:

1992

File:

PDF, 526 KB

1992

60

The findings of the Agency for Toxic Substances and Disease Registry Medical Waste Tracking Act report.

Lichtveld, M Y, Rodenbeck, S E, Lybarger, J A

Journal:

Environmental Health Perspectives

Year:

1992

File:

PDF, 1.76 MB

1992

61

Perinatal and multigenerational effect of carcinogens: possible contribution to determination of cancer susceptibility.

Yamasaki, H, Loktionov, A, Tomatis, L

Journal:

Environmental Health Perspectives

Year:

1992

File:

PDF, 1.03 MB

1992

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