Volume 7; Issue 4

European Journal of Cancer Supplements

Volume 7; Issue 4

1

Editorial Board

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European Journal of Cancer Supplements

Year:

2009

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english

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2

SP140 Gene methylation biomarkers for lung cancer risk, recurrence, and prognosis

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European Journal of Cancer Supplements

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2009

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english

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3

Acknowledgements

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European Journal of Cancer Supplements

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2009

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4

Alphabetical list of exhibitors

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European Journal of Cancer Supplements

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2009

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5

Welcome address

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European Journal of Cancer Supplements

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2009

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english

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6

Faculty list

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European Journal of Cancer Supplements

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2009

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english

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7

Societies' profiles

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European Journal of Cancer Supplements

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2009

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english

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8

Scientific Program – Overview

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European Journal of Cancer Supplements

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2009

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english

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9

Scientific Program – Details

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European Journal of Cancer Supplements

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2009

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english

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10

Faculty's Biosketches

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European Journal of Cancer Supplements

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2009

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english

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11

SP139 Leukemic stem cells

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European Journal of Cancer Supplements

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2009

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english

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12

SP149 Validation of statistically reliable biomarkers

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European Journal of Cancer Supplements

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2009

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english

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13

SP141 Serum proteomics in lung cancer

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European Journal of Cancer Supplements

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2009

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english

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14

SP158 The use of autoantibodies in the early detection of cancer

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European Journal of Cancer Supplements

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2009

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english

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15

SP153 Stem cells and breast cancer: treatment resistance, markers and novel therapeutic targets

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European Journal of Cancer Supplements

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2009

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english

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SP165 Optimizing information obtained from fine needle aspiration (FNA) biopsies

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European Journal of Cancer Supplements

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2009

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english

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17

SP175 Application of high resolution mass spectrometry for cancer biomarker discovery and validation

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European Journal of Cancer Supplements

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2009

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english

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18

SP156 New targets and cancer therapy: successes and failures

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European Journal of Cancer Supplements

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2009

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english

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19

SP147 Pharmacogenomics in pancreatic cancer

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European Journal of Cancer Supplements

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2009

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english

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20

SP157 Informed consent for future research: how much can/should we ask upfront & afterwards

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European Journal of Cancer Supplements

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2009

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english

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21

SP174 Gene signatures: Are we ready to change clinical management in cancer patient treatment?

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European Journal of Cancer Supplements

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2009

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english

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22

SP168 Clinical relevance of circulating tumor cells (CTC) in primary and metastatic breast cancer

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European Journal of Cancer Supplements

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2009

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english

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23

SP142 Molecular imaging

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European Journal of Cancer Supplements

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2009

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english

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SP171 Prognostic and predictive signatures in breast cancer: update and future perspectives

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European Journal of Cancer Supplements

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2009

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english

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25

SP160 Targeted therapies directed against EML4-ALK translocations and BRAF mutations in patients with lung cancer

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European Journal of Cancer Supplements

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2009

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english

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SP164 Biomarker research: the patient perspective

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European Journal of Cancer Supplements

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2009

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english

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SP162 Clinical application of biomarkers: discovery, validation, and application

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European Journal of Cancer Supplements

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2009

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english

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SP150 Pharmacogenomics in colon cancer

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European Journal of Cancer Supplements

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2009

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english

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SP151 Current challenges in the design and conduct of pharmacogenetic and pharmacogenomic studies

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European Journal of Cancer Supplements

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2009

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english

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SP145 PET imaging in upper GI Cancer – past experience and current EORTC initiatives

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European Journal of Cancer Supplements

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2009

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english

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SP169 Gap & priorities: Biomarker integration in drug development

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European Journal of Cancer Supplements

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2009

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english

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SP172 Getting the most from the least tissue

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European Journal of Cancer Supplements

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2009

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english

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SP163 BMP4 and the inhibitors of differentiation, Id-1 and Id-3, play an essential role in the maintenance of colon cancer-initiating cells

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European Journal of Cancer Supplements

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2009

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english

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SP154 The role of pharmacogenetics and pharmacogenomics in cancer therapy

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European Journal of Cancer Supplements

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2009

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english

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SP143 Cancer stem cells and the microenvironment: The role of hypoxia

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European Journal of Cancer Supplements

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2009

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english

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36

SP152 Beyond immunohistochemistry: Accurate, reproducible and quantitative measurement of protein analyte concentrations in fixed tissue

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European Journal of Cancer Supplements

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2009

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english

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SP167 Methodology and design of phase 0 and phase 2 trials with biomarker variables and endpoints

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European Journal of Cancer Supplements

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2009

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english

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SP148 Emerging tissue-based cancer biomarkers in breast cancer

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European Journal of Cancer Supplements

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2009

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english

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SP173 Predictive markers for EGFR targeting therapies

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European Journal of Cancer Supplements

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2009

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english

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SP146 Coordinating biological material collection in the context of multinational clinical trials

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European Journal of Cancer Supplements

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2009

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english

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41

SP161 NNBC3 Europe – Evaluation of the ASCO recommended prognostic factors uPA/PAI-1 in node negative breast cancer patients

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European Journal of Cancer Supplements

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2009

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english

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42

OP62 Polymorphisms in AKT1 and EGFR as possible new biomarkers of clinical outcome and toxicity in non-small-cell lung cancer patients treated with gefitinib

E. Giovannetti, P. Zucali, C. Tibaldi, E. Smit, A. Falcone, A. Santoro, L. Leon, G. Giaccone, R. Danesi, G. Peters

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European Journal of Cancer Supplements

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2009

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english

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43

OP82 Diagnostic performance of soluble mesothelin and megakaryocyte potentiating factor as biomarkers of mesothelioma

K. Hollevoet, K. Nackaerts, J. Thimpont, P. Germonpré, P. De Vuyst, L. Bosqueé, C. Legrand, K. Yoshiro, J. Delanghe, J. van Meerbeeck

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European Journal of Cancer Supplements

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2009

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english

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44

OP125 Downregulation of EZH2 is associated with estrogen receptor upregulation and favourable outcome to tamoxifen in advanced breast cancer

E. Reijm, K. Ruigrok-Ritstier, I. van Staveren, M. Look, M. Meijer-van Gelder, A. Sieuwerts, S. Sleijfer, J. Foekens, E. Berns, M. Jansen

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European Journal of Cancer Supplements

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2009

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english

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OP78 EGFR mutations based on circulating free DNA (cfDNA) in the subset of Japanese patients (pts) from IPASS (IRESSA Pan ASia Study), a Phase III study of first-line gefitinib (G) vs carboplatin/paclitaxel (C/P) in clinically selected patients with advanced non-small-cell lung cancer (NSCLC)

N. Yamamoto, Y. Ichinose, Y. Nishiwaki, Y. Ohe, K. Nishio, H. Jiang, E. Duffield, N. Saijo, T. Mok, M. Fukuoka

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European Journal of Cancer Supplements

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2009

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english

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PP112 A quantitative methylation specific PCR assay to determine promoter methylation status of the MGMT gene

S. Anderson, L. Can, J. Howitt, L. Kam-Morgan, M. Eisenberg

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European Journal of Cancer Supplements

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2009

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english

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PP102 Monitoring BCG immunotherapy for high risk urothelial cancer of the urinary bladder – a novel biomarker

P.U. Ardelt, B. Kneitz, P. Adam, C. Reiss, A. Kocot, J. Fensterle, R. Pasqualini, W. Arap, E.W. Gerharz, H. Riedmiller

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European Journal of Cancer Supplements

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2009

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english

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48

PP92 Molecular changes predicting response to therapy and prognosis among patients with stage IIIB breast cancer

F. Atzori, G. Palmieri, M.T. Ionta, M.C. Sini, M. Budroni, M.C. Deidda, V. Pusceddu, F. Piras, P. Demurtas, B. Massidda

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European Journal of Cancer Supplements

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2009

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english

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PP22 TGFB1–509C>T and IL10–92C>A polymorphic variants in relationship to breast cancer progression and response to neoadjuvant chemotherapy

N. Babyshkina, A. Shevchenko, N. Cherdyntseva, E. Slonimskaya

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European Journal of Cancer Supplements

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2009

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english

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50

PP61 Detection of breast cancer markers in serum by surface-enhanced laser desorption/ionisation time-of-flight mass spectrometry (SELDI-TOF-MS)

D. Boehm, A. Lebrecht, K. Keller, R. Schwirz, M. Schmidt, F. Grus, H. Koelbl

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European Journal of Cancer Supplements

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2009

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english

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51

PP97 The human carcinoembryonic antigen (CEA) predicts therapeutic response towards VEGF-targeting therapies in colorectal cancer

K. Brämswig, G.W. Prager, A. Martel, M. Pöttler, G. Heinze, B.R. Binder, T. Brodowicz, G. Kornek, W. Scheithauer, C.C. Zielinski

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European Journal of Cancer Supplements

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2009

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english

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52

PP74 Detection of K-RAS oncogene mutations using PCR and pyrosequencing

L. Cai, L. Kam-Morgan, M. Eisenberg, S. Anderson

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European Journal of Cancer Supplements

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2009

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english

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PP109 Comparability and reliability of different approaches to obtain gene expression measurements from formalin-fixed, paraffin-embedded breast cancer samples

M. Callari, V. Musella, P. Miodini, L. De Cecco, M.G. Daidone, V. Cappelletti

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European Journal of Cancer Supplements

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2009

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english

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PP108 Genes associated to development of distant metastases in node negative breast cancer patients

V. Cappelletti, M. Callari, L. De Cecco, P. Miodini, V. Musella, L. Sensi, M.L. Carcangiu, S. Veneroni, M.G. Daidone

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European Journal of Cancer Supplements

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2009

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english

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PP111 Examination of the expression profiles of PGIS and TXS in NSCLC: Regulation of tumor cell growth and invasive potential

M.-C. Cathcart, K. Gately, E. Kay, J.V. Reynolds, K.J. O'Byrne

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European Journal of Cancer Supplements

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2009

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english

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PP86 Sister chromatid exchanges as marker of genomic instability in familial breast cancer patients

P. Chiarappa, M. Bruno, C. D'Amico, N. Muscaridola, R. Daprile, A. Paradiso, A. Mangia

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European Journal of Cancer Supplements

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2009

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english

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PP55 A MAGE-A3 specific quantitative RT-PCR assay used for patient accrual in MAGRIT, a Phase III ASCI (Antigen-Specific Cancer Immunotherapeutic) trial in adjuvant NSCLC

T. Coche, J. Louahed, O. Gruselle, H. Wu, H. Hoffmann, E. Esteban-Gonzales, P. Therasse

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European Journal of Cancer Supplements

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2009

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english

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PP56 Prostate-specific antigen doubling time in metastatic castration-resistant prostate cancer: a clinically useful prognostic factor

G. Colloca, D. Guarneri, G. Addamo, A. Venturino, Z. Coccorullo, R. Ratti, E. Campora

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European Journal of Cancer Supplements

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2009

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english

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PP25 Correlation between clinical prognostic factors and MR spectroscopy-based biomarkers determined at 3.0 T without endorectal coils for patients with localised prostate cancer

G. Crehange, S. Parfait, M. Liegard, D. Ben Salem, P. Maingon, M. Funes de la Vega, L. Cormier, F. Bonnetain, F. Brunotte, P. Walker

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European Journal of Cancer Supplements

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english

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PP38 Proteomic analysis of plasma from BRCA1/BRCA2 mutation carriers as modifier risk factor of breast cancer

A.B. Custodio, P. Pérez-Segura, J.J. Zamorano, A.J. López-Farré, E. Olivera, J. Puente, E. Díaz-Rubio

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European Journal of Cancer Supplements

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2009

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PP17 The predictive value of HLA Class I tumor cell expression and tumor infiltration by regulatory T cells for chemotherapy in patients with early breast cancer

E. de Kruijf, J. van Nes, A. Sajet, H. Putter, S. Osanto, F. Speetjens, V. Smit, G.J. Liefers, C. van de Velde, P. Kuppen

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European Journal of Cancer Supplements

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2009

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PP28 Prediction of response to neo-adjuvant radiotherapy in patients with locally advanced rectal cancer by means of sequential 18F-FDG-PET

M. De Ridder, H. Everaert, A. Horens, B. Engels, C. Vanhove, A. Sermeus, D. Debruyne, D. Verellen, D. Urbain, G. Storme

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European Journal of Cancer Supplements

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2009

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english

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PP20 Clinical significance of the epidermal growth factor receptors (EGFR and HER-2) overexpression in esophageal squamous cell cancer

V. Delektorskaya, G. Chemeris, P. Kononec, A. Grigorchuk

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European Journal of Cancer Supplements

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2009

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english

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PP73 Differential staining of SPARC across 3 different tumor types treated with nab-paclitaxel

N. Desai, V. Trieu, D. Knauer, J. Iglesias

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European Journal of Cancer Supplements

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2009

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PP48 A proliferation measure integrates the outcome-related information contained in the breast cancer transcriptome

V. Detours, D. Venet, D. Weiss-Solis, H. Bersini, J. Dumont, C. Maenhaut

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European Journal of Cancer Supplements

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2009

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PP26 Immune response to gastrin-17 is an independent covariate for improved survival in gastrointestinal cancers

L. DiMichele, J. Weidman, J.M. Oortgiesen

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European Journal of Cancer Supplements

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2009

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PP11 Expression differences of proteolytic factors uPA, PAI-1, and seven kallikrein-related peptidases (KLK5, 6, 7, 8, 10, 11, 13) between primary tumor and omentum metastasis impact outcome in advanced ovarian cancer

J. Dorn, N. Harbeck, R. Kates, A. Gkazepis, A. Scorilas, A. Soosaipillai, E. Diamandis, M. Kiechle, B. Schmalfeldt, M. Schmitt

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European Journal of Cancer Supplements

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2009

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PP29 Tissue factor expression in colorectal cancer: a surrogate for KRAS and p53?

J.W. Feilchenfeldt, L.-X. Qin, A.A. Jungbluth, J. Rak, G. Nash, Z. Zeng, F. Barany, J. Shia, P. Paty, N. Kemeny

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European Journal of Cancer Supplements

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PP53 Hakai – a novel tissue based tumour progression marker

A. Figueroa, M. del Mar Haz Conde, M. Blanco Calvo, I. Santamarina Cainzos, V. Medina Villaamil, P. Iglesias, L.A. Aparicio, M. Valladares Ayerbes

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European Journal of Cancer Supplements

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2009

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english

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PP119 VEGF polymorphisms as predictors of bevacizumab efficacy in metastatic colorectal cancer

V. Formica, R. Palmirotta, G. Del Monte, A. Savonarola, G. Ludovici, M.L. De Marchis, I. Grenga, M. Schirru, F. Guadagni, M. Roselli

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European Journal of Cancer Supplements

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2009

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PP70 Cdk4/6 inhibition sensitizes medulloblastoma-derived stem like cells to ionizing radiation

A. Foy, H. Ye, J. Sarkaria, C. Wetmore

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European Journal of Cancer Supplements

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2009

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english

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PP107 The molecular basis of the chemosensitivity of cutaneous melanoma to chemotherapy

F.G. Gabriel, S. Glaysher, R. Chalk, P. Johnson, K. Peregrin, J. Smith, L.A. Knight, M.E. Polak, J. Hurren, I.A. Cree

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European Journal of Cancer Supplements

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2009

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english

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PP12 Signature of miRNA in TEL/AML1-positive acute lymphoblastic leukemia: potential regulation of CD9 expression

V. Gandemer, A. Vallee, J. Bonneau, A.-G. Rio, T. Zenz, M.-D. Galibert

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European Journal of Cancer Supplements

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2009

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english

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PP129 Molecular biomarker analysis of clinical prostate biopsy specimens: Tissue print techniques simplify development of DNA methylation marker tests while preserving the FFPE specimen for histology

S. Gaston, A. Guerra, J. Meadows, J. Bigley, I. Renard, J. Louwagie, K. Bierau

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European Journal of Cancer Supplements

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2009

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english

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PP121 High coexpression of both the epidermal growth factor receptor (EGFR) and insulin-like growth factor receptor-1 (IGF-1R) correlates with a poor patient prognosis in resected non-small cell lung cancer (NSCLC).

K. Gately, L. Forde, S. Cuffe, R. Cummins, E. Kay, K. O'Byrne

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European Journal of Cancer Supplements

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2009

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english

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PP81 18F-FDG PET/CT for early detection of relapse in head and neck squamous cell carcinoma

Journal:

European Journal of Cancer Supplements

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2009

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english

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PP14 RRM1 expression in muscle invasive, locally advanced urothelial cancer is associated with survival in younger patients

L. Harshman, G. Bepler, Z. Zheng, J. Higgins, G. Allen, S. Srinivas

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European Journal of Cancer Supplements

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2009

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english

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PP16 Metronomic weekly use of zoledronic acid for breast cancer with bone metastases has more potent antitumor and bone-preserving effects than conventional zoledronic acid given every-four-weeks

X. Hu, X. Zhao, X. Xu, J. Ragaz, H. Guo, J. Wu, Z. Shao, X. Guo, J. Chen, Z. Wang

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European Journal of Cancer Supplements

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2009

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english

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PP65 PIK3CA mutations in patients with advanced cancers treated in a phase I clinic

F. Janku, D.S. Hong, A.M. Tsimberidou, A. Naing, G.S. Falchook, J.J. Wheler, S.L. Moulder, R. Kurzrock

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European Journal of Cancer Supplements

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2009

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english

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PP104 TYMS and DPYD polymorphisms and toxicity of 5-fluorouracil and capecitabine chemotherapy in colon cancer patients

M. Jokić, M. Gamulin, I. Poparić, M. Grgić, S. Kapitanović

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European Journal of Cancer Supplements

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2009

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english

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PP51 Heat shock of tumor cells at sublethal temperatures causes an immediate phosphorylation of the C-terminal hydrophobic motive of Akt

E. Kampmann, V. Sujeva, K. Tschoep, C. Paulmann, R.D. Issels

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European Journal of Cancer Supplements

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2009

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english

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PP87 Etoposide/platinum therapy, UGT1A1 and GSTP1 polymorphisms, and toxicity in children with solid tumors

S. Kapitanovic, T. Catela Ivkovic, G. Jakovljevic, J. Stepan Giljevic

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European Journal of Cancer Supplements

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2009

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english

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PP128 Expression profiling of BRCA1 and BRCA2 deficient human tumours and cell-lines using a breast specific platform to identify a biomarker of DNA repair deficiency

P. Kerr, J. Mulligan, V. Farztdinov, F. McDyer, I. Halfpenny, T. Delaney, F. Couch, J. Quinn, P. Harkin, R. Kennedy

Journal:

European Journal of Cancer Supplements

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2009

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english

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84

PP117 Increased EGFR gene copy number is variably associated with both EGFR and KRAS Mutation (Mt) status and influences Progression Free Survival (PFS) to first-line chemotherapy in EGFR/KRAS wildtype (WT) patients

S. Kono, A.C. Tan, P. Bunn, A. Davies, R. Doebele, A. Oton, F. Hirsch, M. Varella-Garcia, W. Franklin, D.R. Camidge

Journal:

European Journal of Cancer Supplements

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2009

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english

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PP126 Quantitative protein analysis in FFPE tissue: Application to the tissue microenvironment

D. Krizman, M. Ford, R. Jones, M. Darfler

Journal:

European Journal of Cancer Supplements

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2009

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english

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PP116 Lycopene and prostate cancer

N. Kumar, J. Powsang

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European Journal of Cancer Supplements

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2009

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english

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PP60 Correlation of absolute lymphocyte count with clinical benefit and overall survival: results of compassionate-use trial of ipilimumab in advanced melanoma at Memorial Sloan-Kettering Cancer Center

G. Ku, J. Yuan, S. Schroeder, D. Page, K. Panageas, R. Carvajal, P. Chapman, G. Schwartz, J. Allison, J. Wolchok

Journal:

European Journal of Cancer Supplements

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2009

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english

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PP52 Amplification of the chromosome 17 q22 amplicon containing TOP2A gene is correlated with better survival in HER2 amplified/hormone receptors negative breast cancers

P.-J. Lamy, F. Fina, A.-C. Servanton, C. Dussert, L'H. Ouafik, W. Jacot, P.-M. Martin

Journal:

European Journal of Cancer Supplements

Year:

2009

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english

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PP114 Non-coding mitochondrial RNA differential expression: a new biomarker for noninvasive cancer diagnosis

E. Landerer, V. Burzio, A. Rivas, C. López, L.O. Burzio, J. Villegas

Journal:

European Journal of Cancer Supplements

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2009

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english

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PP23 Immunohistochemical marker profile in colorectal cancer: Our experience

S. Maksimovic, B. Jakovljevic

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

91

PP84 Na+/H+ exchanger regulatory factor 1 (NHERF1) and angiogenesis in familial breast cancer

A. Mangia, A. Malfettone, A. Bellizzi, C. Saponaro, C. Salvatore, G. Simone, A. Paradiso

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

92

PP19 Randomised phase III clinical trial of 5 different arms of treatment for patients with cancer-related anorexia/cachexia syndrome (CACS)

G. Mantovani, C. Madeddu, A. Maccio', F. Panzone, R. Serpe, M. Dessi', G. Antoni, E. Massa, G. Astara

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

93

PP106 DNA promoter methylation in breast cancer as possible biomarkers for screening breast cancer and association with molecular breast cancer subtypes

J. Martinez-Galan, B. Torres-Torres, R. Del Moral, V. Conde, R. Luque, J. Valdivia, M.I. Nunez, M. Villalobos, J.R. Delgado, M. Ruiz de Almodovar

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

94

PP83 Implementation and cost effectiveness of intra-operative qRT-PCR analysis of sentinel lymph nodes (SLN) in breast cancer

A. McDowell, R. Cutress, F. Gabriel, M. Jeffrey, A. Agrawal, M. Wise, C. Yiangou, J. Raftery, I. Cree

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

95

PP44 Development of a quantitative scoring algorithm for a Dual-Hapten, Dual-Color ISH assay (DDISH) to determine HER2 gene status

A. McElhinny, J. Ranger-Moore, I. Loftin, L. Wang, M. Loftus, R. Tubbs, T. Grogan, P. Roche

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

96

PP58 Novel potential therapeutic targets for cholangiocarcinoma identified by array comparative hybridization

S. Mckay, K. Unger, D. Spalding, R. Hutchins, G. Thomas, G. Stamp

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

97

PP47 First line gefitinib versus first line chemotherapy by carboplatin plus paclitaxel in non-small cell lung cancer patients with EGFR mutations: a phase III study (002) by North East Japan Gefitinib Study Group

Y. Minegishi, A. Inoue, K. Kobayashi, A. Gemma, M. Maemondo, S. Oizumi, Y. Saijo, S. Morita, K. Hagiwara, T. Nukiwa

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

98

PP113 Cetuximab with irinotecan/folinic acid/5-FU as first-line treatment inadvanced gastric cancer: A prospective multi-center phase II study and its molecular markers of the Arbeitsgemeinschaft Internistische Onkologie

A. Mueller, S. Schwarz, S. Biesterfeld, S. Kanzler, T. Trarbach, T. Seufferlein, S. Kubicka, F. Lordick, P.R. Galle, M. Moehler

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

99

PP110 Effect of fixative and sample age on success rate in gene profiling studies

V. Musella, P. Miodini, M. Callari, A. Carbone, M.G. Daidone, V. Cappelletti

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

100

PP137 Immunohistochemistry in cancer medicine: our experience in Cameroun

B. Nkegoum, V.J. Ama Moor, M.J. Atanga, T. Mbah

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

101

PP72 Demonstration of dose-dependent target inhibition using a quantitative biomarker assay for SB939, a potent, orally active HDAC inhibitor, in a Phase I clinical study in solid tumors

V. Novotny-Diermayr, A.-L. Liang, Y.K. Loh, H. Hentze, R. Jayaraman, K. Ethirajulu, J. Zhu, J.M. Wood

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

102

PP32 A unified approach to define incidence of acute kidney injury (AKI) with serum creatinine as biomarker

G. Nowshad, S. Alam, M.H. Rahbar, A.K. Salahudeen

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

103

PP120 Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis in resected non-small cell lung cancer

D. O'Callaghan, E. Rexhepaj, K. Gately, D. Delany, F. O'Connell, E. Kay, W. Gallagher, K. O'Byrne

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

104

PP138 A whole blood RNA transcript-based model to predict biopsy Gleason score in newly diagnosed prostate cancer patients

W. Oh, J. Magidson, D. Bankaitis-Davis, L. Siconolfi, B. Schurko, R. Cantu, S. Braitsch, K. Wassman, P. Kantoff, R. Ross

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

105

PP90 Hereditary transmission of polymorphisms in familial breast cancer

B. Pilato, R. Pinto, D. Petriella, K. Danza, M. Martinucci, G. Iannelli, M. Bruno, C. D'Amico, A. Paradiso, S. Tommasi

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

106

PP43 RCL2 fixation of neurosurgical specimens: well preserved histomorphology and DNA integrity

M. Preusser, S. Plumer, E. Dirnberger, J. Hainfellner, C. Mannhalter

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

107

PP98 High expression of hsa-miR-30a-3p, hsa-miR-30c and hsa-miR-182 predict favorable outcome on tamoxifen treatment in patients with recurrent breast cancer

F.G. Rodríguez-González, A.M. Sieuwerts, V. de Weerd, M.P. Look, M. Smid, M.E. Meijer-van Gelder, J.W.M. Martens, J.A. Foekens

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

108

PP122 Intraoperative tissue fluorescence using 5-aminolevolinic acid (ALA) is more sensitive than contrast-MRI or amino acid (FET)-PET guided glioblastoma (GBM) surgery

K. Roessler, A. Becherer, I. Zachenhofer, M. Donat, M. Cejna

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

109

PP127 INHANCE (Iressa™ Novel Head and Neck Chemotherapy Evaluation) randomised phase II trial: clinical findings and associated translational research into EGFR-related biomarkers in tumour and skin biopsies

S. Rogers, R. Collier, E. Clark, M. Tanay, J. Hickey, C. Box, P. Rhys-Evans, C. Nutting, S. Eccles, K. Harrington

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

110

PP63 Predictive markers in patients with upper gastrointestinal (GI) cancers treated with erlotinib and bevacizumab in a multicenter phase II trial

K.S. Rohrberg, I. Buysschaert, H. Pappot, B. Guldhammer Skov, I.J. Christensen, R.K. Olesen, M. Ladekarl, P. Pfeiffer, P. Carmeliet, U. Lassen

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

111

PP103 RT-PCR-based UCA1 expression detection in urine samples as non-invasive reliable method for urothelial cancer diagnosis

S. Rorive, F. Sandras, L. Biskri, C. Fossion, X. Catteau, T. Roumeguere, M. Vanden Bossche, T. Mijatovic, I. Salmon

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

112

PP24 CXCR4: a predictive marker of bone metastases in breast cancer patients

E. Sacanna, T. Ibrahim, M. Gaudio, L. Mercatali, R. Ricci, E. Scarpi, M. Ricci, P. Serra, D. Amadori

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

113

PP33 Functional characterization of CYP2C8 promoter polymorphisms

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

114

PP89 Upregulated p38 MAPK signaling in circulating pancreatic cancer cells

G. Sergeant, R. van Eijsden, J. Allemeersch, V. Van Duppen, R. Aers, T. Roskams, N. Ectors, P. Van Hummelen, J. Van Pelt, B. Topal

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

115

PP67 Early alpha-fetoprotein response predicts treatment efficacy of anti-angiogenic therapy in combination with metronomic chemotherapy for advanced hepatocellular carcinoma

Y.-Y. Shao, Z.-Z. Lin, C. Hsu, Y.-C. Shen, C.-H. Hsu, A.-L. Cheng

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

116

PP35 Dual use of single WT-1 immunohistochemistry in evaluation of ovarian tumors: a preliminary study of 20 cases

S. Siddiqui, Y.-H. Hsiao, W. Wang, Y.-g. Man

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

117

PP95 Predictive mRNA and microRNA markers of response to the HDAC inhibitor PCI-24781 in colorectal tumors

M. Sirisawad, L. Tee, H. Mamuszka, J.J. Buggy

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

118

PP27 Expression of microRNA-221 is progressively reduced in aggressive prostate cancer and metastasis and predicts clinical recurrence

M. Spahn, S. Kneitz, C.-J. Scholz, N. Stenger, T. Rüdiger, P. Ströbel, H. Riedmiller, B. Kneitz

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

119

PP59 Prognostic significance of aB-crystallin, vimentin and HSP 27 association in primary breast cancer

R. Sreseli, P. Quinlan, R. Quinlan, S. Hadad, S. Bray, D. Kellock, L. Baker, L. Jordan, C. Purdie, A. Thompson

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

120

PP118 Detection and quantification of EGF receptor phosphorylation in formalin-fixed tumor sections by selected/multiple reaction monitoring mass spectrometry

P. Taylor, J. Tong, W. Shih, M.M. Darfler, M.S. Tsao, D.B. Krizman, C. Eitner, M.F. Moran

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

121

PP94 The Chernobyl Tissue Bank – a model for integrating “omics” research on single blocks of tissue

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

122

PP85 Genotyping of microsatellite alterations and EGFR somatic mutations in exhaled breath condensate of NSCLC patients

S. Tommasi, G.E. Carpagnano, R. Pinto, M.P. Foschino-Barbaro, A. Spanevello, F. Carpagnano, G. Mulè, A. Paradiso

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 66 KB

english, 2009

123

PP45 Analytical performance of a novel dual color dual hapten brightfield genotypic assay for determination of HER2 status in breast carcinoma (DDISH)

R. Tubbs, I. Loftin, L. Wang, R. Miller, M. Sugarman, M. Loftus, J. Pettay, J. Ranger-Moore, A. McElhinny, P. Roche

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

124

PP93 Molecular heterogeneity in G3 N0 breast cancer – better treatment tailoring for patients of different ages?

K. Unger, S. Oliveros, H. Zitzelsberger, S. Riley, C. Davies, W. Williams, R. Leonard, G. Thomas

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

125

PP64 Prognostic relevance of isocitrate dehydrogenase I and II mutations and MGMT promoter hypermethylation in diffuse astrocytomas

L. Valletta, S. Guzzetti, A.L. Di Stefano, E. Maderna, B. Pollo, G. Finocchiaro, M. Eoli

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

126

PP96 Tumor tissue profiling at the drug targeting level: kinase activity

R. van Beuningen, R. Ruijtenbeek, L. Houkes, R. de Wijn, P. Boender, R. Hilhorst

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

127

PP77 CPT1C, a promising anticancer target in the treatment of hypoxic brain tumours

K. Zaugg, I. Lohse, J. Feng, N. Macedo-Sanchez, T. Mak

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 34 KB

english, 2009

128

P46 The volatile fingerprint of melanoma

T. Abaffy, R. Duncan, D. Riemer, G. Elgart, J. Keri, R. DeFazio

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

129

P68 Proteomic changes in colorectal cancer cell lines in response to sorafenib treatment

T. Auer, G. Gamerith, B. Sarg, D. Mueller, H. Zwierzina, H. Lindner, W. Hilbe, J. Loeffler-Ragg

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

130

P31 Aurora kinase B: expression and potential therapeutic target in malignant pleural mesothelioma. An in vitro study

P.-G. Betta, T. Bensi, R. Libener, M. Salvio, E. Arnolfo, F. Ugo, M. Botta, E. Piccolini, S. Orecchia

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

131

P41 Transcribed ultraconserved elements expression in tumour cell lines

M. Blanco, M. Haz, M. Reboredo, V. Medina, I. Santamarina, P. Iglesias, L.A. Aparicio, M. Valladares

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 67 KB

english, 2009

132

P99 Rho C in melanoma: possible target for statin treatment?

L. Brochez, T. Malfait, B. Boone, J. Lambert, R. Kiss, V. Mathieu

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

133

P10 Detection of circulating tumor cells (CTCs) in Stage cT3–4orN+ rectal cancer patients (pts) undergoing combined neoadjuvant therapy plus curative surgery. Preliminary data

G. Contino, E. Bertani, G.M. Zampino, L. Zorzino, E. Magni, B. Andreoni, M.T. Sandri, A. Chiappa

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

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english, 2009

134

P30 Assessment of oxidative stress in tumor cells and normal mucosa cells from head and neck squamous cell carcinoma patients

D. Dequanter, K. Zouaoui, V. Nuyens, A. Rousseau, D. Brohée, M. Vanhaeverbeek, Ph. Lothaire

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

135

P34 Reduced p63 expression in myoepithelium correlating with increased invasiveness in epithelium

Y.-H. Hsiao, C. Deng, Y.A. Su, H.-D. Tsai, X. Wang, J.T. Mason, M.-C. Chou, Y.-g. Man

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

136

P75 A promising method for visualization of immune responses in immunoproteomics

K. Keller, D. Boehm, A. Lebrecht, H. Koelbl, F. Grus

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

137

P115 Green tea catechins mixture (Polyphenon E) is an equally potent proteasome-inhibitor as purified EGCG

N. Kumar, A. Kazi, S. Said

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

138

P71 Vascular endothelial growth factor (VEGF) inhibition and erythropoiesis – a missing link?

M.S. Kuruvilla, A. Benger, H. Hirte, S. Hotte

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

139

P39 Response of non small cell lung cancer xenografts to targeted therapies is not related to epithelial-to-mesenchymal transition

J. Rolff, A. Lamich, I. Fichtner

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

140

P134 A sensitive tamoxifen response profile in patients with metastatic breast cancer indicates that an Interferon-gamma (IFN-g) centered cellular immune response is involved in tamoxifen resistance

S. Tian, A. Glas, M. Kok, I. Simon, M. Snel, M.P.H.M. Jansen, L.F.A. Wessels, S. Linn, E.M.J.J. Berns, L. van 't Veer

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

141

P124 MicroRNAs as circulating tumor cells biomarkers in gastrointestinal cancer

M. Valladares-Ayerbes, V. Medina Villaamil, M. Reboredo López, A. Carral Maseda, S.M. Díaz Prado, M. Blanco Calvo, I. Santamarina Caínzos, M. Haz Conde, L.M. Antón Aparicio

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

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english, 2009

142

P136 KRAS mutation is highly correlated with EGFR alterations in patients with non-small cell lung cancer

J.-Y. Wang, S.-R. Lin

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

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english, 2009

143

P54 Irradiation-enhanced mammalian target of rapamycin (mTOR)-targeted glioblastoma therapy with CCI-779 (temsirolimus)

M. Weiler, P.-N. Pfenning, A.-L. Thiepold, L. Jestaedt, B. Berger, M. Bendszus, W. Wick

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 54 KB

english, 2009

144

Author index

Journal:

European Journal of Cancer Supplements

Year:

2009

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2009

145

Abstract index

Journal:

European Journal of Cancer Supplements

Year:

2009

File:

PDF, 27 KB

2009