Volume 109

European Journal of Medicinal Chemistry

Volume 109

1

Arylpiperidines as a new class of oxidosqualene cyclase inhibitors

Keller, Marco, Wolfgardt, Annette, Müller, Christoph, Wilcken, Rainer, Böckler, Frank M., Oliaro-Bosso, Simonetta, Ferrante, Terenzio, Balliano, Gianni, Bracher, Franz

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1021 KB

english, 2016

2

Silibinin derivatives as anti-prostate cancer agents: Synthesis and cell-based evaluations

Vue, Bao, Zhang, Sheng, Zhang, Xiaojie, Parisis, Konstantinos, Zhang, Qiang, Zheng, Shilong, Wang, Guangdi, Chen, Qiao-Hong

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.14 MB

english, 2016

3

Synthesis and structure of new dicopper(II) complexes bridged by N-(2-hydroxy-5-methylphenyl)-N′-[3-(dimethylamino)propyl]oxamide with in vitro anticancer activity: A comparative study of reactivities towards DNA/protein by molecular docking and experimental assays

Zheng, Kang, Yan, Mei-Xing, Li, Yan-Tuan, Wu, Zhi-Yong, Yan, Cui-Wei

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 2.55 MB

english, 2016

4

Prospective of curcumin, a pleiotropic signalling molecule from Curcuma longa in the treatment of Glioblastoma

Luthra, Pratibha Mehta, Lal, Neetika

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 2.36 MB

english, 2016

5

Design and synthesis of pyrrolobenzodiazepine-gallic hybrid agents as p53-dependent and -independent apoptogenic signaling in melanoma cells

Chou, Yu-Wei, Senadi, Gopal Chandru, Chen, Chung-Yu, Kuo, Kung-Kai, Lin, Ying-Ting, Wang, Jeh-Jeng, Lee, Jia-Hau, Wang, Ya-Ching, Hu, Wan-Ping

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 3.23 MB

english, 2016

6

Synthesis of dihydrosterculic acid-based monoglucosyl diacylglycerol and its analogues and their biological evaluation

Srikanth, Vudhgiri, Prasad, R.B.N., Poornachandra, Y., Phani Babu, V.S., Ganesh Kumar, C., Jagadeesh, B., Jala, Ram Chandra Reddy

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.52 MB

english, 2016

7

Neuroprotective profile of pyridothiazepines with blocking activity of the mitochondrial Na+/Ca2+ exchanger

Martínez-Sanz, Francisco J., Lajarín-Cuesta, Rocío, González-Lafuente, Laura, Moreno-Ortega, Ana J., Punzón, Eva, Cano-Abad, María F., de los Ríos, Cristóbal

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 907 KB

english, 2016

8

Novel 2-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,3,4-oxadiazole and 3-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,2,4-oxadiazole derivatives as dengue virus inhibitors targeting NS5 polymerase

Benmansour, Fatiha, Eydoux, Cécilia, Querat, Gilles, de Lamballerie, Xavier, Canard, Bruno, Alvarez, Karine, Guillemot, Jean-Claude, Barral, Karine

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.33 MB

english, 2016

9

Design, synthesis, and biological evaluation of crenatoside analogues as novel influenza neuraminidase inhibitors

Chen, Bao-Long, Wang, Ya-Jing, Guo, Hong, Zeng, Guang-Yao

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 871 KB

english, 2016

10

Cytotoxicity and apoptotic activity of novel organobismuth(V) and organoantimony(V) complexes in different cancer cell lines

Islam, Arshad, Rodrigues, Bernardo Lages, Marzano, Ivana Marques, Perreira-Maia, Elene C., Dittz, Dalton, Paz Lopes, Miriam Teresa, Ishfaq, Muhammad, Frézard, Frédéric, Demicheli, Cynthia

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 2.18 MB

english, 2016

11

Inhibition of tau aggregation using a naturally-occurring cyclic peptide scaffold

Wang, Conan K., Northfield, Susan E., Huang, Yen-Hua, Ramos, Mariana C., Craik, David J.

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.77 MB

english, 2016

12

Synthesis of diacylated γ-glutamyl-cysteamine prodrugs, and in vitro evaluation of their cytotoxicity and intracellular delivery of cysteamine

Frost, Lisa, Suryadevara, Pratap, Cannell, Stephanie J., Groundwater, Paul W., Hambleton, Paul A., Anderson, Rosaleen J.

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 782 KB

english, 2016

13

Identification of N-(6-mercaptohexyl)-3-(4-pyridyl)-1H-pyrazole-5-carboxamide and its disulfide prodrug as potent histone deacetylase inhibitors with in vitro and in vivo anti-tumor efficacy

Wen, Jiachen, Bao, Yu, Niu, Qun, Yang, Jinyu, Fan, Yinbo, Li, Jinhua, Jing, Yongkui, Zhao, Linxiang, Liu, Dan

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.62 MB

english, 2016

14

Melatonergic ligands: Design, synthesis and pharmacological evaluation of novel series of naphthofuranic derivatives

Landagaray, Elodie, Ettaoussi, Mohamed, Duroux, Romain, Boutin, Jean A., Caignard, Daniel-Henri, Delagrange, Philippe, Melnyk, Patricia, Berthelot, Pascal, Yous, Saïd

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 557 KB

english, 2016

15

Design, synthesis and anti-HIV evaluation of novel diarylpyridine derivatives targeting the entrance channel of NNRTI binding pocket

Yang, Jiapei, Chen, Wenmin, Kang, Dongwei, Lu, Xueyi, Li, Xiao, Liu, Zhaoqiang, Huang, Boshi, Daelemans, Dirk, Pannecouque, Christophe, De Clercq, Erik, Zhan, Peng, Liu, Xinyong

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.06 MB

english, 2016

16

Synthesis of 2-arylfuro[3,2-b]pyridines: Effect of the C2-aryl group on melatoninergic activity

Couhert, Audrey, Delagrange, Philippe, Caignard, Daniel-Henri, Chartier, Agnès, Suzenet, Franck, Guillaumet, Gérald

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.11 MB

english, 2016

17

A comparison of novel organoiridium(III) complexes and their ligands as a potential treatment for prostate cancer

Hockey, Samantha C., Barbante, Gregory J., Francis, Paul S., Altimari, Jarrad M., Yoganantharajah, Prusothman, Gibert, Yann, Henderson, Luke C.

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 875 KB

english, 2016

18

Editorial board

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 57 KB

english, 2016

19

Graphical contents list

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 2.23 MB

english, 2016