Volume 131

European Journal of Medicinal Chemistry

Volume 131

1

Discovery of N -(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl)phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-( tert -butyl)benzamide (CHMFL-BTK-01) as a highly selective irreversible Bruton's tyrosine kinase (BTK) inhibitor

Liang, Qianmao, Chen, Yongfei, Yu, Kailin, Chen, Cheng, Zhang, Shouxiang, Wang, Aoli, Wang, Wei, Wu, Hong, Liu, Xiaochuan, Wang, Beilei, Wang, Li, Hu, Zhenquan, Wang, Wenchao, Ren, Tao, Zhang, Shanchu

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 4.64 MB

english, 2017

2

Prodrugs of triterpenoids and their derivatives

Zhou, Meng, Zhang, Rong-Hong, Wang, Min, Xu, Guo-Bo, Liao, Shang-Gao

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.00 MB

english, 2017

3

Coumarin sulfonates: New alkaline phosphatase inhibitors; in vitro and in silico studies

Salar, Uzma, Khan, Khalid Mohammed, Iqbal, Jamshed, Ejaz, Syeda Abida, Hameed, Abdul, al-Rashida, Mariya, Perveen, Shahnaz, Tahir, Muhammad Nawaz

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.68 MB

english, 2017

4

Development of 2, 4-diaminoquinazoline derivatives as potent PAK4 inhibitors by the core refinement strategy

Hao, Chenzhou, Huang, Wanxu, Li, Xiaodong, Guo, Jing, Chen, Meng, Yan, Zizheng, Wang, Kai, Jiang, Xiaolin, Song, Shuai, Wang, Jian, Zhao, Dongmei, Li, Feng, Cheng, Maosheng

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.80 MB

english, 2017

5

Therapeutic potentials of baicalin and its aglycone, baicalein against inflammatory disorders

Dinda, Biswanath, Dinda, Subhajit, DasSharma, Saikat, Banik, Rajarshi, Chakraborty, Ankita, Dinda, Manikarna

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 678 KB

english, 2017

6

Synthesis, screening and docking of fused pyrano[3,2- d ]pyrimidine derivatives as xanthine oxidase inhibitor

Kaur, Manroopraj, Kaur, Amandeep, Mankotia, Suhani, Singh, Harbinder, Singh, Arshdeep, Singh, Jatinder Vir, Gupta, Manish Kumar, Sharma, Sahil, Nepali, Kunal, Bedi, Preet Mohinder Singh

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 793 KB

english, 2017

7

Synthesis of heterocyclic ring-fused tricyclic diterpene analogs as novel inhibitors of RANKL-induced osteoclastogenesis and bone resorption

Wei, Gao, Wu, Yalan, He, Xiao-Long, Liu, Ting, Liu, Mingyao, Luo, Jian, Qiu, Wen-Wei

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.88 MB

english, 2017

8

MAO enzymes inhibitory activity of new benzimidazole derivatives including hydrazone and propargyl side chains

Can, Özgür Devrim, Osmaniye, Derya, Demir Özkay, Ümide, Sağlık, Begüm Nurpelin, Levent, Serkan, Ilgın, Sinem, Baysal, Merve, Özkay, Yusuf, Kaplancıklı, Zafer Asım

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 3.47 MB

english, 2017

9

Synthesis and antiplasmodial activity of novel indoleamide derivatives bearing sulfonamide and triazole pharmacophores

Devender, N., Gunjan, Sarika, Tripathi, Renu, Tripathi, Rama Pati

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 708 KB

english, 2017

10

(−)-UB006: A new fatty acid synthase inhibitor and cytotoxic agent without anorexic side effects

Makowski, Kamil, Mir, Joan Francesc, Mera, Paula, Ariza, Xavier, Asins, Guillermina, Hegardt, Fausto G., Herrero, Laura, García, Jordi, Serra, Dolors

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.81 MB

english, 2017

11

New bis(hydroxymethyl) alkanoate curcuminoid derivatives exhibit activity against triple-negative breast cancer in vitro and in vivo

Hsieh, Min-Tsang, Chang, Ling-Chu, Hung, Hsin-Yi, Lin, Hui-Yi, Shih, Mei-Hui, Tsai, Chang-Hai, Kuo, Sheng-Chu, Lee, Kuo-Hsiung

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.10 MB

english, 2017

12

Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents

El-Gohary, N.S., Shaaban, M.I.

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 546 KB

english, 2017

13

Systematic study of imidazoles inhibiting IDO1 via the integration of molecular mechanics and quantum mechanics calculations

Zou, Yi, Wang, Fang, Wang, Yan, Guo, Wenjie, Zhang, Yihua, Xu, Qiang, Lai, Yisheng

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 3.46 MB

english, 2017

14

N -Piperonyl substitution on aminoquinoline-pyrimidine hybrids: Effect on the antiplasmodial potency

Kholiya, Rohit, Khan, Shabana I., Bahuguna, Aparna, Tripathi, Mohit, Rawat, Diwan S.

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.58 MB

english, 2017

15

Synthesis and biological evaluation of novel podophyllotoxin-NSAIDs conjugates as multifunctional anti-MDR agents against resistant human hepatocellular carcinoma Bel-7402/5-FU cells

Zhang, Lei, Liu, Lai, Zheng, Chengyue, Wang, Yang, Nie, Xuqiang, Shi, Dabin, Chen, Yongzheng, Wei, Gang, Wang, Jing

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 4.26 MB

english, 2017

16

Synthesis of novel quinoline–based 4,5–dihydro–1 H –pyrazoles as potential anticancer, antifungal, antibacterial and antiprotozoal agents

Ramírez–Prada, Jonathan, Robledo, Sara M., Vélez, Iván D., Crespo, María del Pilar, Quiroga, Jairo, Abonia, Rodrigo, Montoya, Alba, Svetaz, Laura, Zacchino, Susana, Insuasty, Braulio

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 809 KB

english, 2017

17

An in vivo active 1,2,5-oxadiazole Pt(II) complex: A promising anticancer agent endowed with STAT3 inhibitory properties

Porta, Federica, Facchetti, Giorgio, Ferri, Nicola, Gelain, Arianna, Meneghetti, Fiorella, Villa, Stefania, Barlocco, Daniela, Masciocchi, Daniela, Asai, Akira, Miyoshi, Nao, Marchianò, Silvia, Kwon,

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 889 KB

english, 2017

18

Morpholine or methylpiperazine and salicylaldimine based heteroleptic square planner platinum (II) complexes: In vitro anticancer study and growth retardation effect on E. coli

Rahman, Faiz-Ur, Ali, Amjad, Khan, Inam Ullah, Duong, Hong-Quan, Yu, Shang-Bo, Lin, Yue-Jian, Wang, Hui, Li, Zhan-Ting, Zhang, Dan-Wei

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 5.02 MB

english, 2017

19

Synthesis, molecular docking, antimycobacterial and antimicrobial evaluation of new pyrrolo[3,2- c ]pyridine Mannich bases

Jose, Gilish, Suresha Kumara, Tholappanavara H., Sowmya, Haliwana B.V., Sriram, Dharmarajan, Guru Row, Tayur N., Hosamani, Amar A., More, Sunil S., Janardhan, Bhavya, Harish, B.G., Telkar, Sandeep, Ra

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 3.60 MB

english, 2017

20

Recent updates of carbapenem antibiotics

El-Gamal, Mohammed I., Brahim, Imen, Hisham, Noorhan, Aladdin, Rand, Mohammed, Haneen, Bahaaeldin, Amany

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 773 KB

english, 2017

21

Editorial board

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 57 KB

english, 2017

22

Graphical contents list

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.37 MB

english, 2017