Volume 157

European Journal of Medicinal Chemistry

Volume 157

1

Synthesis and biological evaluation of dihydroquinoline carboxamide derivatives as anti-tubercular agents

Kumar, Gautam, Sathe, Asawari, Krishna, Vagolu Siva, Sriram, Dharmarajan, Jachak, Sanjay M.

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.14 MB

english, 2018

2

Novel hydrazido benzenesulfonamides-isatin conjugates: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies

Abo-Ashour, Mahmoud F., Eldehna, Wagdy M., Nocentini, Alessio, Ibrahim, Hany S., Bua, Silvia, Abou-Seri, Sahar M., Supuran, Claudiu T.

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.11 MB

english, 2018

3

Novel selenadiazole derivatives as selective antitumor and radical scavenging agents

Ruberte, Ana Carolina, Plano, Daniel, Encío, Ignacio, Aydillo, Carlos, Sharma, Arun K., Sanmartín, Carmen

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.19 MB

english, 2018

4

Synthesis, pharmacology and preclinical evaluation of 11C-labeled 1,3-dihydro-2H-benzo[d]imidazole-2-ones for imaging γ8-dependent transmembrane AMPA receptor regulatory protein

Chen, Zhen, Mori, Wakana, Zhang, Xiaofei, Yamasaki, Tomoteru, Dunn, Patrick J., Zhang, Genwei, Fu, Hualong, Shao, Tuo, Zhang, Yiding, Hatori, Akiko, Ma, Longle, Fujinaga, Masayuki, Xie, Lin, Deng, Xia

Journal:

European Journal of Medicinal Chemistry

Year:

2018

File:

PDF, 2.65 MB

2018

5

Design, synthesis and biological evaluation of novel ferrocene-pyrazole derivatives containing nitric oxide donors as COX-2 inhibitors for cancer therapy

Ren, Shen-Zhen, Wang, Zhong-Chang, Zhu, Dan, Zhu, Xiao-Hua, Shen, Fa-Qian, Wu, Song-Yu, Chen, Jin-Jin, Xu, Chen, Zhu, Hai-Liang

Journal:

European Journal of Medicinal Chemistry

Year:

2018

File:

PDF, 1.62 MB

2018

6

Bioactive heterocycles containing a 3,4,5-trimethoxyphenyl fragment exerting potent antiproliferative activity through microtubule destabilization

Fu, Dong-Jun, Yang, Jia-Jia, Li, Ping, Hou, Yu-Hui, Huang, Sheng-Nan, Tippin, Matthew Alexander, Pham, Victor, Song, Liankun, Zi, Xiaolin, Xue, Wei-Li, Zhang, Li-Rong, Zhang, Sai-Yang

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 4.13 MB

english, 2018

7

Recent advances in the medical use of silver complex

Liang, Xiaoxia, Luan, Shangxian, Yin, Zhongqiong, He, Min, He, Changliang, Yin, Lizi, Zou, Yuanfeng, Yuan, Zhixiang, Li, Lixia, Song, Xu, Lv, Chen, Zhang, Wei

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 874 KB

english, 2018

8

Difuran-substituted quinoxalines as a novel class of PI3Kα H1047R mutant inhibitors: Synthesis, biological evaluation and structure-activity relationship

Zhang, Ning, Yu, Zhimei, Yang, Xiaohong, Zhou, Yan, Tang, Qing, Hu, Ping, Wang, Jia, Zhang, Shao-Lin, Wang, Ming-Wei, He, Yun

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.41 MB

english, 2018

9

Donepezil-butylated hydroxytoluene (BHT) hybrids as Anti-Alzheimer's disease agents with cholinergic, antioxidant, and neuroprotective properties

Cai, Pei, Fang, Si-Qiang, Yang, Hua-Li, Yang, Xue-Lian, Liu, Qiao-Hong, Kong, Ling-Yi, Wang, Xiao-Bing

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 3.85 MB

english, 2018

10

Discovery of a potent non-oxime reactivator of nerve agent inhibited human acetylcholinesterase

de Koning, Martijn Constantijn, Horn, Gabriele, Worek, Franz, van Grol, Marco

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.60 MB

english, 2018

11

99m Tc(CO) 3 + labeled domain I/II-specific anti-EGFR (scFv) 2 antibody fragment for imaging EGFR expression

Solomon, Viswas Raja, Gonzalez, Carolina, Alizadeh, Elahe, Bernhard, Wendy, Hartimath, Siddesh V., Barreto, Kris, Geyer, Clarence Ronald, Fonge, Humphrey

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.44 MB

english, 2018

12

Synthesis, pharmacology and preclinical evaluation of 11C-labeled 1,3-dihydro-2H-benzo[d]imidazole-2-ones for imaging γ8-dependent transmembrane AMPA receptor regulatory protein

Chen, Zhen, Mori, Wakana, Zhang, Xiaofei, Yamasaki, Tomoteru, Dunn, Patrick J., Zhang, Genwei, Fu, Hualong, Shao, Tuo, Zhang, Yiding, Hatori, Akiko, Ma, Longle, Fujinaga, Masayuki, Xie, Lin, Deng, Xia

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.65 MB

english, 2018

13

Design, synthesis and biological evaluation of novel ferrocene-pyrazole derivatives containing nitric oxide donors as COX-2 inhibitors for cancer therapy

Ren, Shen-Zhen, Wang, Zhong-Chang, Zhu, Dan, Zhu, Xiao-Hua, Shen, Fa-Qian, Wu, Song-Yu, Chen, Jin-Jin, Xu, Chen, Zhu, Hai-Liang

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.62 MB

english, 2018

14

Conjugation of a 5-nitrofuran-2-oyl moiety to aminoalkylimidazoles produces non-toxic nitrofurans that are efficacious in vitro and in vivo against multidrug-resistant Mycobacterium tuberculosis

Krasavin, Mikhail, Lukin, Alexei, Vedekhina, Tatiana, Manicheva, Olga, Dogonadze, Marine, Vinogradova, Tatiana, Zabolotnykh, Natalia, Rogacheva, Elizaveta, Kraeva, Liudmila, Yablonsky, Piotr

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.73 MB

english, 2018

15

HDAC3 is a potential validated target for cancer: An overview on the benzamide-based selective HDAC3 inhibitors through comparative SAR/QSAR/QAAR approaches

Adhikari, Nilanjan, Amin, Sk. Abdul, Trivedi, Prakruti, Jha, Tarun, Ghosh, Balaram

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.37 MB

english, 2018

16

Breathing new life into West Nile virus therapeutics; discovery and study of zafirlukast as an NS2B-NS3 protease inhibitor

Martinez, Anastasia A., Espinosa, Bianca A., Adamek, Rebecca N., Thomas, Brent A., Chau, Jennifer, Gonzalez, Edwardo, Keppetipola, Niroshika, Salzameda, Nicholas T.

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.18 MB

english, 2018

17

Corrigendum to “An improved 99mTc-HYNIC-(Ser)3-LTVSPWY peptide with EDDA/tricine as co-ligands for targeting and imaging of HER2 overexpression tumor” [EJMECH 144, (2018) 767–773]

Khodadust, F., Ahmadpour, S., Aligholikhamseh, N., Abedi, S.M., Hosseinimehr, S.J.

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 201 KB

english, 2018

18

Corrigendum to “Novel natural compounds from endophytic fungi with anticancer activity” [EJMECH 156, (2018) 316–343]

Li, Shou-Jie, Zhang, Xuan, Wang, Xiang-Hua, Zhao, Chang-Qi

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 168 KB

english, 2018

19

Structure-activity and structure-property relationships of novel Nrf2 activators with a 1,2,4-oxadiazole core and their therapeutic effects on acetaminophen (APAP)-induced acute liver injury

Xu, Li-Li, Wu, Yu-Feng, Wang, Lei, Li, Cui-Cui, Li, Li, Di, Bin, You, Qi-Dong, Jiang, Zheng-Yu

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 3.05 MB

english, 2018

20

Graphical abstract TOC

Journal:

European Journal of Medicinal Chemistry

Year:

2018

File:

PDF, 296 KB

2018

21

Graphical abstract TOC

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 230 KB

english, 2018

22

Editorial Board

Journal:

European Journal of Medicinal Chemistry

Year:

2018

File:

PDF, 34 KB

2018