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Volume 209
Main
European Journal of Medicinal Chemistry
Volume 209
European Journal of Medicinal Chemistry
Volume 209
1
Design, synthesis and biological evaluation of indanoneâchalcone hybrids as potent and selective hCES2A inhibitors
Huo, Peng-Chao
,
Guan, Xiao-Qing
,
Liu, Peng
,
Song, Yun-Qing
,
Sun, Meng-Ru
,
He, Rong-Jing
,
Zou, Li-Wei
,
Xue, Li-Juan
,
Shi, Jin-Hui
,
Zhang, Nan
,
Liu, Zhi-Guo
,
Ge, Guang-Bo
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 1.67 MB
Your tags:
2021
2
New imidazopyridines with phosphodiesterase 4 and 7 inhibitory activity and their efficacy in animal models of inflammatory and autoimmune diseases
RuÄilová, Veronika
,
Åwierczek, Artur
,
Vanda, David
,
Funk, Petr
,
Lemrová, Barbora
,
Gawalska, Alicja
,
Bucki, Adam
,
Nowak, Barbara
,
Zadrożna, Monika
,
Pociecha, Krzysztof
,
Soural, Miroslav
,
Wyska, El
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 7.31 MB
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2021
3
Meroterpenoids produced by fungi: Occurrence, structural diversity, biological activities, and their molecular targets
Zhao, Min
,
Tang, Yuqian
,
Xie, Jingwen
,
Zhao, Zhongxiang
,
Cui, Hui
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 2.26 MB
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2021
4
Amphiphilic desmuramyl peptides for the rational design of new vaccine adjuvants: Synthesis, in vitro modulation of inflammatory response and molecular docking studies
Khan, Farooq-Ahmad
,
Nasim, Nourina
,
Wang, Yan
,
Alhazmi, Alaa
,
Sanam, Mehar
,
Ul-Haq, Zaheer
,
Yalamati, Damayanthi
,
Ulanova, Marina
,
Jiang, Zi-Hua
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 2.05 MB
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2021
5
A red-light-activated sulfonamide porphycene for highly efficient photodynamic therapy against hypoxic tumor
Wang, Yuzhi
,
Pan, Zhaohai
,
Cheng, Xiao-Lan
,
Zhang, Kai
,
Zhang, Xin
,
Qin, Yao
,
Fan, Jiaojiao
,
Yan, Ting
,
Han, Tao
,
Shiu, Kwok Keung
,
Hau, Sam Chun-Kit
,
Mak, Nai-Ki
,
Kwong, Daniel W.J.
,
Liu, Xiaona
,
Li,
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 6.78 MB
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2021
6
The discovery of potent small molecule activators of human STING
Pryde, David C.
,
Middya, Sandip
,
Banerjee, Monali
,
Shrivastava, Ritesh
,
Basu, Sourav
,
Ghosh, Rajib
,
Yadav, Dharmendra B.
,
Surya, Arjun
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 2.81 MB
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2021
7
Squaric acid analogues in medicinal chemistry
Chasák, Jan
,
Šlachtová, Veronika
,
Urban, Milan
,
BrulÃková, Lucie
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 959 KB
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2021
8
Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation
Pecnard, Shannon
,
Provot, Olivier
,
Levaique, Hélène
,
Bignon, Jérome
,
Askenatzis, Laurie
,
Saller, Francois
,
Borgel, Delphine
,
Michallet, Sophie
,
Laisne, Marie-Catherine
,
Lafanechère, Laurence
,
Alam
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 4.16 MB
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2021
9
Design and synthesis of 3-(4-pyridyl)-5-(4-sulfamido-phenyl)-1,2,4-oxadiazole derivatives as novel GSK-3β inhibitors and evaluation of their potential as multifunctional anti-Alzheimer agents
Wang, Min
,
Liu, Tongtong
,
Chen, Shiming
,
Wu, Mingfei
,
Han, Jianfei
,
Li, Zeng
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 2.73 MB
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2021
10
Anti-tuberculosis activity and its structure-activity relationship (SAR) studies of oxadiazole derivatives: A key review
Verma, Santosh Kumar
,
Verma, Rameshwari
,
Verma, Shekhar
,
Vaishnav, Yogesh
,
Tiwari, S.P.
,
Rakesh, K.P.
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 1.64 MB
Your tags:
2021
11
Mercaptoacetamide: A promising zinc-binding group for the discovery of selective histone deacetylase 6 inhibitors
Tavares, MaurÃcio T.
,
Kozikowski, Alan P.
,
Shen, Sida
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 2.83 MB
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2021
12
Novel 3-substituted coumarins as selective human carbonic anhydrase IX and XII inhibitors: Synthesis, biological and molecular dynamics analysis
Abdelrahman, Mohamed A.
,
Ibrahim, Hany S.
,
Nocentini, Alessio
,
Eldehna, Wagdy M.
,
Bonardi, Alessandro
,
Abdel-Aziz, Hatem A.
,
Gratteri, Paola
,
Abou-Seri, Sahar M.
,
Supuran, Claudiu T.
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 2.27 MB
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2021
13
Protease activated receptor 4 (PAR4) antagonists: Research progress on small molecules in the field of antiplatelet agents
Liu, Shangde
,
Li, Shanshan
,
Yuan, Duo
,
Wang, Enmao
,
Xie, Roujie
,
Zhang, Weiqi
,
Kong, Yi
,
Zhu, Xiong
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 2.96 MB
Your tags:
2021
14
Cytotoxic triterpenoidâsafirinium conjugates target the endoplasmic reticulum
Kraft, Oliver
,
Kozubek, Marie
,
Hoenke, Sophie
,
Serbian, Immo
,
Major, Daniel
,
Csuk, René
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 1.16 MB
Your tags:
2021
15
Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion
Bouzina, Abdeslem
,
Berredjem, Malika
,
Nocentini, Alessio
,
Bua, Silvia
,
Bouaziz, Zouhair
,
Jose, Joachim
,
Le Borgne, Marc
,
Marminon, Christelle
,
Gratteri, Paola
,
Supuran, Claudiu T.
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 1.34 MB
Your tags:
2021
16
Structure-guided modification of isoxazole-type FXR agonists: Identification of a potent and orally bioavailable FXR modulator
Luo, Guoshun
,
Lin, Xin
,
Li, Zhenbang
,
Xiao, Maoxu
,
Li, Xinyu
,
Zhang, Dayong
,
Xiang, Hua
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 1.65 MB
Your tags:
2021
17
Current development of CBP/p300 inhibitors in the last decade
He, Zhang-Xu
,
Wei, Bing-Fei
,
Zhang, Xin
,
Gong, Yun-Peng
,
Ma, Li-Ying
,
Zhao, Wen
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 8.60 MB
Your tags:
2021
18
Extension of furopyrimidine nucleosides with 5-alkynyl substituent: Synthesis, high fluorescence, and antiviral effect in the absence of free ribose hydroxyl groups
Kaczmarek, Renata
,
Twardy, Dylan J.
,
Olson, Trevor L.
,
KorczyÅski, Dariusz
,
Andrei, Graciela
,
Snoeck, Robert
,
Dolot, RafaÅ
,
Wheeler, Kraig A.
,
Dembinski, Roman
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 1010 KB
Your tags:
2021
19
Development of pyrene-based fluorescent ether lipid as inhibitor of SK3 ion channels
Bauduin, Alicia
,
Papin, Marion
,
Chantôme, Aurélie
,
Couthon, Hélène
,
Deschamps, Laure
,
Requejo-Isidro, Jose
,
Vandier, Christophe
,
Jaffrès, Paul-Alain
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 2.10 MB
Your tags:
2021
20
Synthesis, binding, and functional properties of tetrahydroisoquinolino-2-alkyl phenones as selective Ï2R/TMEM97 ligands
Xie, Xiao-Yang
,
Li, Yu-Yun
,
Ma, Wen-Hui
,
Chen, Ai-Fang
,
Sun, Yu-Tong
,
Lee, Ji Youn
,
Riad, Aladdin
,
Xu, Dao-Hua
,
Mach, Robert H.
,
Huang, Yun-Sheng
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 734 KB
Your tags:
2021
21
Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors
Granchi, Carlotta
,
Bononi, Giulia
,
Ferrisi, Rebecca
,
Gori, Eleonora
,
Mantini, Giulia
,
Glasmacher, Sandra
,
Poli, Giulio
,
Palazzolo, Stefano
,
Caligiuri, Isabella
,
Rizzolio, Flavio
,
Canzonieri, Vincenzo
,
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 4.20 MB
Your tags:
2021
22
Methionine aminopeptidases with short sequence inserts within the catalytic domain are differentially inhibited: Structural and biochemical studies of three proteins from Vibrio spp.
Pillalamarri, Vijaykumar
,
Reddy, Chilakala Gangi
,
Bala, Sandeep Chowdary
,
Jangam, Aruna
,
Kutty, Vinny Vinod
,
Addlagatta, Anthony
Journal:
European Journal of Medicinal Chemistry
Year:
2021
File:
PDF, 3.53 MB
Your tags:
2021
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