Volume 42; Issue 5

European Journal of Medicinal Chemistry

Volume 42; Issue 5

1

Synthesis of some new bioactive 3-amino-2-mercapto-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one derivatives

B.V. Ashalatha, B. Narayana, K.K. Vijaya Raj, N. Suchetha Kumari

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 261 KB

english, 2007

2

Synthesis, stereochemistry and antimicrobial evaluation of t(3)-benzyl-r(2),c(6)-diarylpiperidin-4-one and its derivatives

J. Jayabharathi, A. Manimekalai, T. Consalata Vani, M. Padmavathy

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 624 KB

english, 2007

3

Chemotherapy of leishmaniasis. Part V: Synthesis and in vitro bioevaluation of novel pyridinone derivatives

Susmita Pandey, S.N. Suryawanshi, Nishi, Neena Goyal, Suman Gupta

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 170 KB

english, 2007

4

Synthesis of novel diarylpyrimidine analogues of TMC278 and their antiviral activity against HIV-1 wild-type and mutant strains

Céline Mordant, Benoit Schmitt, Elisabeth Pasquier, Christophe Demestre, Laurence Queguiner, Chantal Masungi, Anik Peeters, Liesbeth Smeulders, Eva Bettens, Kurt Hertogs, Jan Heeres, Paul Lewi, Jerome

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 343 KB

english, 2007

5

ANN-QSAR model for selection of anticancer leads from structurally heterogeneous series of compounds

Humberto González-Díaz, Isis Bonet, Carmen Terán, Erik De Clercq, Rafael Bello, Maria M. García, Lourdes Santana, Eugenio Uriarte

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 206 KB

english, 2007

6

Optimisation of correlation weights of SMILES invariants for modelling oral quail toxicity

Andrey A. Toropov, Emilio Benfenati

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 232 KB

english, 2007

7

Synthesis and antigenotoxic activity of some naphtho[2,1-b]pyrano[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives

Fakher Chabchoub, Mehdi Messaâd, Hédi Ben Mansour, Leila Chekir-Ghedira, Mansour Salem

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 169 KB

english, 2007

8

Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling study

Alaa A.-M. Abdel-Aziz

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 837 KB

english, 2007

9

4-Methyl-1,2,3-selenadiazole-5-carboxylic acid amides: Antitumor action and cytotoxic effect correlation

Pavel Arsenyan, Kira Rubina, Irina Shestakova, Ilona Domracheva

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 626 KB

english, 2007

10

New 5-substituted thiazolo[3,2-b][1,2,4]triazol-6-ones: Synthesis and anticancer evaluation

Roman Lesyk, Olena Vladzimirska, Serhiy Holota, Lucjusz Zaprutko, Andrzej Gzella

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 256 KB

english, 2007

11

Impact on farnesyltransferase inhibition of 4-chlorophenyl moiety replacement in the Zarnestra® series

Patrick Angibaud, Laurence Mevellec, Christophe Meyer, Xavier Bourdrez, Patricia Lezouret, Isabelle Pilatte, Virginie Poncelet, Bruno Roux, Sophie Merillon, David W. End, Jacky Van Dun, Walter Wouters

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 606 KB

english, 2007

12

Glutamine vinyl ester proteasome inhibitors selective for trypsin-like (β2) subunit

Anna Baldisserotto, Mauro Marastoni, Claudio Trapella, Riccardo Gavioli, Valeria Ferretti, Loretta Pretto, Roberto Tomatis

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 281 KB

english, 2007

13

Synthetic 2′,5′-dimethoxychalcones as G2/M arrest-mediated apoptosis-inducing agents and inhibitors of nitric oxide production in rat macrophages

Bai-Luh Wei, Chi-Huang Teng, Jih-Pyang Wang, Shen-Jeu Won, Chun-Nan Lin

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 2.10 MB

english, 2007

14

Synthetic N-pyridinyl(methyl)-indol-3-ylpropanamides as new potential immunosuppressive agents

Delphine Carbonnelle, Morgane Lardic, Alexandra Dassonville, Elise Verron, Jean-Yves Petit, Muriel Duflos, François Lang

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 436 KB

english, 2007

15

Acid-catalyzed synthesis of oxathiolone fused chalcones. Comparison of their activity toward various microorganisms and human cancer cells line

Marek T. Konieczny, Wojciech Konieczny, Michał Sabisz, Andrzej Skladanowski, Roland Wakieć, Ewa Augustynowicz-Kopeć, Zofia Zwolska

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 163 KB

english, 2007

16

Robust fuzzy mappings for QSAR studies

Mohit Kumar, Kerstin Thurow, Norbert Stoll, Regina Stoll

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 576 KB

english, 2007

17

Type III collagen mimetic peptides designed with anti- or pro-aggregant activities on human platelets

Viviane Pires, Julien Pêcher, Sophie Da Nascimento, Pascal Maurice, Arnaud Bonnefoy, Alexandra Dassonville, Carole Amant, Françoise Fauvel-Lafève, Chantal Legrand, Jacques Rochette, Pascal Sonnet

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 319 KB

english, 2007

18

Metal complexes of retinoid derivatives with antiproliferative activity: Synthesis, characterization and DNA interaction studies

F. Bisceglie, M. Baldini, M. Belicchi-Ferrari, E. Buluggiu, M. Careri, G. Pelosi, S. Pinelli, P. Tarasconi

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 454 KB

english, 2007

19

Application of genetic algorithm-kernel partial least square as a novel nonlinear feature selection method: Activity of carbonic anhydrase II inhibitors

Mehdi Jalali-Heravi, Anahita Kyani

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 366 KB

english, 2007

20

Editorial board

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 39 KB

english, 2007

21

Graphical contents list

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 526 KB

english, 2007