Volume 41; Issue 1

Accounts of Chemical Research

Volume 41; Issue 1

1

Design of HIV Protease Inhibitors Targeting Protein Backbone: An Effective Strategy for Combating Drug Resistance

Ghosh, Arun K., Chapsal, Bruno D., Weber, Irene T., Mitsuya, Hiroaki

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 375 KB

english, 2008

2

Targeting Mitochondria

Hoye, Adam T., Davoren, Jennifer E., Wipf, Peter, Fink, Mitchell P., Kagan, Valerian E.

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 1.01 MB

english, 2008

3

Discovery and Development of Folic-Acid-Based Receptor Targeting for Imaging and Therapy of Cancer and Inflammatory Diseases

Low, Philip S., Henne, Walter A., Doorneweerd, Derek D.

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 1.33 MB

english, 2008

4

Function-Oriented Synthesis, Step Economy, and Drug Design

Wender, Paul A., Verma, Vishal A., Paxton, Thomas J., Pillow, Thomas H.

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 1.80 MB

english, 2008

5

Challenges in Modern Drug Discovery: A Case Study of Boceprevir, an HCV Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

Njoroge, F. George, Chen, Kevin X., Shih, Neng-Yang, Piwinski, John J.

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 1.06 MB

english, 2008

6

Complex Target SELEX

Shamah, Steven M., Healy, Judith M., Cload, Sharon T.

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 909 KB

english, 2008

7

Targeted Cancer Therapy: Conferring Specificity to Cytotoxic Drugs

Chari, Ravi V. J.

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 1.20 MB

english, 2008

8

Functionalized Carbon Nanotubes in Drug Design and Discovery

Prato, Maurizio, Kostarelos, Kostas, Bianco, Alberto

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 524 KB

english, 2008

9

Hybrid Molecules with a Dual Mode of Action: Dream or Reality? †

Meunier, Bernard

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 880 KB

english, 2008

10

Inhibitors of FabI, an Enzyme Drug Target in the Bacterial Fatty Acid Biosynthesis Pathway

Lu, Hao, Tonge, Peter J.

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 1019 KB

english, 2008

11

Evaluating Drug Efficacy and Toxicology in Three Dimensions: Using Synthetic Extracellular Matrices in Drug Discovery

Prestwich, Glenn D.

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 1.14 MB

english, 2008

12

Modern Molecular Approaches to Drug Design and Discovery

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 63 KB

english, 2008

13

Guided Molecular Missiles for Tumor-Targeting Chemotherapy—Case Studies Using the Second-Generation Taxoids as Warheads

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 1.91 MB

english, 2008

14

The Chemical Versatility of Natural-Product Assembly Lines

Walsh, Christopher T.

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 1.33 MB

english, 2008

15

Discovery and Combinatorial Synthesis of Fungal Metabolites Beauveriolides, Novel Antiatherosclerotic Agents

Tomoda, Hiroshi, Doi, Takayuki

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 888 KB

english, 2008

16

Editorial

Valentine, Joan Selverstone, Houk, Kendall N., Barbara, Paul F.

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 52 KB

english, 2008

17

Epothilones as Lead Structures for the Synthesis-Based Discovery of New Chemotypes for Microtubule Stabilization

Feyen, Fabian, Cachoux, Frédéric, Gertsch, Jürg, Wartmann, Markus, Altmann, Karl-Heinz

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 331 KB

english, 2008