Volume 24

Growth Hormone & IGF Research

Volume 24

1

Impact of the growth hormone replacement on bone status in growth hormone deficient adults

Kužma, M., Kužmová, Z., Zelinková, Z., Killinger, Z., Vaňuga, P., Lazurová, I., Tomková, S., Payer, J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 565 KB

english, 2014

2

Effects of thyroid hormone on the GH signal transduction pathway

Ocaranza, Paula, Lammoglia, Juan Javier, Íñiguez, Germán, Román, Rossana, Cassorla, Fernando

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 361 KB

english, 2014

3

Effects of the regulation of follistatin mRNA expression by IGF-1 in duck (Anas platyrhynchos) skeletal muscle

Liu, Hehe, Li, Xinxin, Sun, Lingli, Wang, Haohan, Zhang, Rongping, Yang, Chao, Li, Liang, Wang, Jiwen, He, Hua, Krumm, Christopher

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 407 KB

english, 2014

4

Administration of growth hormone and nandrolone decanoate alters mRNA expression of the GABAB receptor subunits as well as of the GH receptor, IGF-1, and IGF-2 in rat brain

Grönbladh, Alfhild, Johansson, Jenny, Nyberg, Fred, Hallberg, Mathias

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 897 KB

english, 2014

5

Extrapituitary growth hormone synthesis in humans

Pérez-Ibave, Diana Cristina, Rodríguez-Sánchez, Iram Pablo, Garza-Rodríguez, María de Lourdes, Barrera-Saldaña, Hugo Alberto

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 435 KB

english, 2014

6

Effects of levothyroxine on growth hormone (gh) sensitivity in children with idiopathic short stature

García, Roberto J., Iñiguez, German, Gaete, Ximena, Linares, Jeannette, Ocaranza, Paula, Avila, Alejandra, Roman, Rossana, Cassorla, Fernando

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 308 KB

english, 2014

7

Effect of milk proteins on linear growth and IGF variables in overweight adolescents

Larnkjær, Anni, Arnberg, Karina, Michaelsen, Kim F., Jensen, Signe M., Mølgaard, Christian

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 408 KB

english, 2014

8

Investigation of IGF2, Hedgehog and fusion gene expression profiles in pediatric sarcomas

de Souza, Robson Ramos, Oliveira, Indhira Dias, del Giúdice Paniago, Mario, Yaoita, Fernando Hideki Kato, Caran, Eliana Maria Monteiro, Macedo, Carla Renata Pacheco Donato, Petrilli, Antonio Sergio, A

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 599 KB

english, 2014

9

Non-functioning pituitary macroadenomas: Benefit from early growth hormone substitution after surgery

Sauer, Nina, Flitsch, Jörg, Doeing, Inga, Dannheim, Viola, Burkhardt, Till, Aberle, Jens

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 391 KB

english, 2014

10

Expression levels of insulin-like growth factors 1 and 2 in head and neck squamous cell carcinoma

Zhi, Xu, Lamperska, Katarzyna, Golusinski, Paweł, Schork, Nicholas J., Luczewski, Lukasz, Golusinski, Wojciech, Masternak, Michal M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 453 KB

english, 2014

11

Exogenous IGF-1 promotes hair growth by stimulating cell proliferation and down regulating TGF-β1 in C57BL/6 mice in vivo

Li, Jingjie, Yang, Zhihong, Li, Zheng, Gu, Lijuan, Wang, Yunbo, Sung, Changkeun

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 1.24 MB

english, 2014

12

Radiometrical, hormonal and biological correlates of skeletal growth in the female rat from birth to senescence

del Pozo, Emilio, Janner, Marco, Mackenzie, Andrew R., Arampatzis, Spyridon, Dixon, Arnold K., Perrelet, Romain, Ruch, Walter, Lippuner, Kurt, Zapf, Juergen, Lamberts, Steven W., Mullis, Primus E.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 1.02 MB

english, 2014

13

Acknowledgement to reviewers - 2013

MurdacaGiuseppe.Murdaca@unige.it, Giuseppe

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 93 KB

english, 2014

14

Corrigendum to “Metabolic alterations in patients who develop traumatic brain injury (TBI)-induced hypopituitarism” [Growth Horm. IGF Res. 23 (4) (2013) 109–113]

Prodam, F., Gasco, V., Caputo, M., Zavattaro, M., Pagano, L., Marzullo, P., Belcastro, S., Busti, A., Perino, C., Grottoli, S., Ghigo, E., Aimaretti, G.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 124 KB

english, 2014

15

Insulin-like growth factor-1 (IGF-1) enhances developmental competence of cat embryos cultured singly by modulating the expression of its receptor (IGF-1R) and reducing developmental block

Thongkittidilok, Chommanart, Tharasanit, Theerawat, Sananmuang, Thanida, Buarpung, Sirirak, Techakumphu, Mongkol

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 472 KB

english, 2014

16

Association between growth hormone therapy and mortality, cancer and cardiovascular risk: Systematic review and meta-analysis

Deodati, Annalisa, Ferroli, Barbara Baldini, Cianfarani, Stefano

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 1.34 MB

english, 2014

17

Glucose homeostasis in adults with Prader–Willi syndrome during treatment with growth hormone: Results from a 12-month prospective study

Jørgensen, Anders Palmstrøm, Ueland, Thor, Sode-Carlsen, Rasmus, Schreiner, Thomas, Rabben, Kai Fredrik, Farholt, Stense, Høybye, Charlotte, Christiansen, Jens Sandahl, Bollerslev, Jens

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 348 KB

english, 2014

18

Transcriptional and epigenetic control of IGF1R gene expression: Implications in metabolism and cancer

Werner, Haim, Sarfstein, Rive

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 292 KB

english, 2014

19

Increased genome instability and oxidative DNA damage and their association with IGF-1 levels in patients with active acromegaly

Bayram, Fahri, Bitgen, Nazmiye, Donmez-Altuntas, Hamiyet, Cakir, Ilkay, Hamurcu, Zuhal, Sahin, Fatma, Simsek, Yasin, Baskol, Gulden

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 319 KB

english, 2014

20

The influence of age and exercise modality on growth hormone bioactivity in women

Gordon, Scott E., Kraemer, William J., Looney, David P., Flanagan, Shawn D., Comstock, Brett A., Hymer, Wesley C.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 718 KB

english, 2014

21

Discordance of IGF-1 and GH stimulation testing for altered GH secretion in obesity

Stanley, Takara L., Feldpausch, Meghan N., Murphy, Caitlin A., Grinspoon, Steven K., Makimura, Hideo

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 246 KB

english, 2014

22

Editorial Board

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 60 KB

english, 2014

23

GLP-1 infusion reduces IGFBP-1 serum level in humans

Skov, Jeppe, Frystyk, Jan, Christiansen, Jens Sandahl

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 358 KB

english, 2014

24

The growth hormone receptor exon 3 polymorphism is not associated with height or metabolic traits in healthy young adults

Martins, Clarissa S., Fernandes-Rosa, Fabio L., Espineira, Aniette R., de Souza, Roberto Molina, de Castro, Margaret, Barbieri, Marco A., Bettiol, Heloisa, Jorge, Alexander L., Antonini, Sonir R.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 577 KB

english, 2014

25

Heat acclimation decreases the growth hormone response to acute constant-load exercise in the heat

Ööpik, Vahur, Timpmann, Saima, Kreegipuu, Kairi, Unt, Eve, Tamm, Maria

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 525 KB

english, 2014

26

IGFBP-3: A cell fate pivot in cancer and disease

Johnson, Michael A., Firth, Sue M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 508 KB

english, 2014

27

Editorial Board

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 58 KB

english, 2014

28

Circulating IGF-axis protein levels and their relation with levels of plasma adipocytokines and macronutrient consumption in women

Beasley, Jeannette M., Wedick, Nicole M., Rajpathak, Swapnil N., Xue, Xiaonan, Holmes, Michelle D., Gunter, Marc J., Wylie-Rosett, Judith, Rohan, Thomas E., Pollak, Michael, Kaplan, Robert C., Hu, Fra

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 387 KB

english, 2014

29

Corneal thickness in children with growth hormone deficiency: The effect of GH treatment

Ciresi, A., Morreale, R., Radellini, S., Cillino, S., Giordano, C.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 289 KB

english, 2014

30

Optimizing IGF-I for skeletal muscle therapeutics

Philippou, Anastassios, Barton, Elisabeth R.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 622 KB

english, 2014

31

hGH isoform differential immunoassays applied to blood samples from athletes: Decision limits for anti-doping testing

Hanley, James A., Saarela, Olli, Stephens, David A., Thalabard, Jean-Christophe

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 4.53 MB

english, 2014

32

PO2-8: Specific measurement of human growth hormone oligomers in blood and its possible clinical application

Wu, Z., Strasburger, C.J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 435 KB

english, 2014

33

PO2-5: Severe headache relieved by short-acting somatostatin analogue in a patient with Acromegaly resistant to longacting somatostatin analogues

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

34

GP4-4: SGA short stature bearing with a novel nonsense mutation (p.W1219X) in the IGF1R gene

Fujimoto, M., Kawashima, Y., Hamajima, T., Miyahara, N., Nishimura, R., Hanaki, K., Kanzaki, S.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 449 KB

english, 2014

35

OR6-2: IRS-1 promotes embryonic growth of zebrafish through IGF-IR signal-dependent and -independent mechanisms in response to developmental stages and environmental oxygen availability

Kamei, H., Sawada, R., Yoneyama, Y., Hakuno, F., Shimizu, T., Takahashi, S.-I.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 440 KB

english, 2014

36

Program at a Glance

Journal:

Growth Hormone & IGF Research

Year:

2014

File:

PDF, 526 KB

2014

37

SY1-5: Growth hormone replacement in adult growth hormone deficiency: long-term efficacy and safety

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 447 KB

english, 2014

38

OR4-1: Randomised controlled clinical trial contrasting current GH doses with dose based on IGF-I titration in children born small for gestational age (NESGAS)

Jensen, R.B., Thankamony, A., O’Connell, S.M., Kirk, J., Donaldson, M., Ivarsson, S.-A., Söder, O., Roche, E., Hoey, H., Dunger, D.B., Juul, A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 450 KB

english, 2014

39

OR2-4: Exogenous administration of protease-resistant, non matrixbinding IGFBP-2 inhibits tumour growth in a murine model of breast cancer

Soh, C.-L., McNeil, K., Owczarek, C.M., Hardy, M., Fabri, L.J., Pearse, M., Delaine, C.A., Forbes, B.E.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 437 KB

english, 2014

40

OR4-4: The causal role of IGFs and IGFBPs in prostate cancer: a Mendelian randomization study

Bonilla, C., Rowlands, M.-A., Lewis, S.J., Palmer, T., Gaunt, T.R., Davey Smith, G., Gunnell, D., Donovan, J.L., Hamdy, F.C., Neal, D.E., Lathrop, M., Martin, R.M., Holly, J.M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 444 KB

english, 2014

41

SY2-4: IGFBP-2 in Cancer: From The Matrix to The Inside Job

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 440 KB

english, 2014

42

PO4-1: Alpha-fetoprotein at birth: an early marker of circulating IGF-I in preterm infants

Kistner, A., Hellgren, G., Hansen Pupp, I., Ley, D., Löfqvist, C., Hellström, A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

43

OR4-3: Safety and effectiveness of Increlex® therapy in children enrolled in the Increlex Growth Forum Database (IGFD) in Europe: 4-year interim results

Bang, P., Polak, M., Woelfle, J., Sicsic, A., Lecanuet, S.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 463 KB

english, 2014

44

PO2-24: Elevated spontaneous trough GH levels are associated with Lipoprotein (a) in short prepubertal children with high waist-hip ratio

Decker, R., Andersson, B., Kriström, B., Nygren, A., Albertsson-Wikland, K.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

45

SY1-3: Dosing and Monitoring GH treatment in children born SGA

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 555 KB

english, 2014

46

SY2-5: The G protein estrogen receptor (GPER) is involved in IGF-I/insulin signaling in cancer cells

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 444 KB

english, 2014

47

OR1-5: Short-term low dose GH therapy improves insulin sensitivity but does not affect cortisol metabolism and ectopic fat accumulation in GH deficient adults

Yuen, K.C.J., Frystyk, J., Klopfenstein, B.J., Rooney, W.D., Purnell, J.Q.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 445 KB

english, 2014

48

PO2-4: Pregnancy in acromegaly patients treated with pegvisomant

Van der Lely, A.J., Gomez, R., Heissler, J.F., Åkerblad, A.-C., Jönsson, P., Camacho-Hübner, C., Kołtowska-Häggström, M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

49

PO3-2: Modulation of IGFBP1 protein expression by metformin

Ansurudeen, I., Brismar, K.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

50

GP2-1: IGF-I ameliorates hepatic fibrosis in mouse models of nonalcoholic steatohepatitis and cirrhosis via inhibiting the activity or hepatic stellate cells

Nishizawa, H., Iguchi, G., Fukuoka, H., Takahashi, M., Suda, K., Bando, H., Matsumoto, R., Takahashi, Y.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 447 KB

english, 2014

51

GP4-3: Epigenetic analyses of the insulin-like growth factor binding protein 1 gene in diabetes and diabetic nephropathy

Gu, T., Gu, H.F., Falhammar, H., Hilding, A., Sjöholm, L.K., Östenson, C.-G., Ekström, T.J., Brismar, K.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 449 KB

english, 2014

52

PO4-4: Cerebrospinal fluid and serum levels of growth hormone (GH), insulin-like-growth factor-I (IGF-1), insulin-like growth factor binding protein -3 (IGFBP-3) and ghrelin in patients with bacterial and tuberculous meningitis

Akinci, A., Gungor, S., Yucel, G., Gungor, S., Ozerol, H.I.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

53

PO3-3: The hepatic expression of GHR and SOCS2 mRNA is increased before ovulation during the follicular phase in dairy cattle

Mense, K., Meyerholz, M., Knaack, H., Lietzau, M., Engelke, J., Hoedemarker, M., Piechotta, M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 455 KB

english, 2014

54

PO4-5: Insulin like growth factor-1 therapy in five patients with growth hormone insensitivity

Ersoy, B., Ozhan, B., Kızılay, D., Kiremitci, S.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

55

OR8-7: Insulin like growth factor-II (IGF-II) regulates mitochondrial phenotype, metabolism and DNA content to prevent apoptosis and to increase energy production efficiency promoting a more aggressive and chemoresistant breast cancer disease

Radhakrishnan, V.K., DeLeon, D.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

56

PO1-5: Socs 2 plays no major role in the increased expression of fibrotic genes in the remnant kidney

Assadi, M.H., Abu Hilal, R., Landau, D., Chen, Y., Medrano, J., Rabkin, R., Segev, Y.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 543 KB

english, 2014

57

OR2-5: Linkage of reproductive development, fat metabolism and lifespan by the RGD-motif of IGFBP-2 in female transgenic mice

Hoeflich, A., Spitschak, M., Ohde, D., Schindler, N., Brenmoehl, J., Langhammer, M., Bielohuby, M., Renner-Müller, I., Wanke, R., Metzger, F., Wolf, E., Zeissler, A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 440 KB

english, 2014

58

OR7-4: A phase 2, six-month dose-response study to investigate TransCon hGH, a long-acting hGH, in treatment naïve children with idiopathic growth hormone deficiency (IGHD)

Chatelain, P., Malievsky, O., Radziuk, K., Elsedfy, H., Mikhailova, E., Beckert, M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

59

OR6-4: Sustained IGF-II production is necessary for adult neurogenesis

Ziegler, A.N., Testai, J., Constancia, M., Sandovici, I., Wood, T.L., Levison, S.W.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

60

GP3-2: Rosiglitazone treatment: acromegaly patients do not differ from normal type 2 diabetics in their IGFBP-1 and Insulin dynamics with euglycemic glucose clamp

Tint, M.T., Khoo, C.M., Cunanan, E., Liew, S., Lee, K.O.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 456 KB

english, 2014

61

PO3-17: Hypermethylation and hypomethylation of IGF-II DMRO (Insulin like growth factors-II Differentially Methylated Region) correlated to increased or decreased expression of IGF-II in breast cancer cells and paired breast tissues of African American and Caucasian breast cancer patients

Radhakrishnan, V.K., De León, M.A., DeLeon, D.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

62

PO3-11: Porphyra yezoensis peptide stimulates the proliferation of IEC-6 cells by activating the insulin-like growth factor-I receptor signaling pathway

Nam, T.-J., Lee, M.-K., Kim, I.-H., Choi, Y.-H.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 441 KB

english, 2014

63

OR7-6: Safety and efficacy of ARX201: six month dose-ranging study of a novel long-acting pegylated growth hormone in young adults with growth hormone deficiency

Racz, K., Coculescu, M., Olyinik, V., Popa, M., Popovic, V., Radiuk, K., Senatorova, A.S., Vlasenko, M.V., Norman, T., Juhasz, M., Hoffman, A.R., Axelrod, D.W.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 444 KB

english, 2014

64

OR5-4: The choice of growth hormone receptor signalling pathway determines longevity

Chhabra, Y., Nelson, C.N., Plescher, M., Brooks, T., Waters, M.J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

65

OR2-1: Impaired mTORC1 activity up-regulates IGFBP-1 synthesis during dietary protein restriction

Takenaka, A., Hino, M., Takeuchi, K., Takahashi, S.-I.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 582 KB

english, 2014

66

PO2-22: Usability and safety of FlexPro® PenMate®, a growth hormone (GH) injection system, in patients, caregivers and healthcare professionals

Wen, Y., Korsholm, C.N., Klinck, R., Kappelgaard, A.-M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

67

PO4-7: Functional selectivity of the insulin-like growth factor type 1 receptor (IGF-1R) signaling: therapeutic implications for cancer treatment

Girnita, L., Crudden, C.J., Suleymanova, N., Oprea, I., Worrall, C., Girnita, A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

68

GP2-2: The deubiquitinating enzyme, USP9X positively regulates insulin-like growth factor (IGF)-dependent cell growth by inhibition of degradation of IGF-I receptor (IGF-IR) and insulin receptor substrate (IRS)-2 in prostate cancer cells

Furuta, H., Yoshihara, H., Fukushima, T., Saeki, Y.S., Ito, A., Worrall, C., Girnita, L., Tanaka, K., Yoshida, M., Asano, T., Chida, K., Hakuno, F., Takahashi, S.-I.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 448 KB

english, 2014

69

PO2-2: An evaluation of the safety and usability of FlexPro® 30 mg/3 mL, for the delivery of Norditropin® in patients requiring growth hormone (GH) therapy

Kappelgaard, A.-M., Wen, Y., Klinck, R., Qvist, M., Fuchs, G.S.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

70

PO3-9: Effects of endurance training on somatic growth in a rat model of chronic kidney disease (CKD)

Troib, A., Guterman, M., Landau, D., Rabkin, R., Segev, Y.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

71

OR7-2: The MOD-4023 story; a long acting GH from proof of concepts in animal models to growth hormone deficient populations clinical studies (adults and pediatric )

Hart, G., Hershkovitz, O., Koren, R., Amitzi, L., Fima, E.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 441 KB

english, 2014

72

OR3-6: Loss of acyl-ghrelin signalling in male ghrelin-O-acyltransferase knock-out mice results in reduced pulsatile growth hormone secretion and a derangement of GH pulse pattern

Xie, T.Y., Ngo, S.T., Veldhuis, J.D., Jeffery, P.L., Chopin, L.K., Tschöp, M., Trolle, V., Epelbaum, J., Steyn, F.J., Chen, C.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 448 KB

english, 2014

73

PO4-6: Serum levels of IGF-I and IGFBP-1 in Indian diabetic population

Tekle, M., Vasan, S., Brismar, K.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 455 KB

english, 2014

74

OR1-3: The molecular mechanism of dominantly inherited short stature caused by GH polymers

Wu, Z., Junnila, R., Strasburger, C.J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 608 KB

english, 2014

75

OR6-6: Dermal fibroblast secreted IGF-I protects skin keratinocytes against ultraviolet B radiation induced damage

Fernandez, T.L., Van Lonkhuyzen, D.R., Dawson, R., Kimlin, M., Upton, Z.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 453 KB

english, 2014

76

OR3-5: NPY neurons as a critical hypothalamic node for the control of GH release relative to food intake

Huang, L., Tan, H., Fogarty, M., Stark, R., Andrews, Z., Veldhuis, J., Herzog, H., Chen, C., Steyn, F.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 448 KB

english, 2014

77

OR7-1: A reversible albumin-binding GH derivative possesses a promising once-weekly treatment profile and is well tolerated in adult subjects with growth hormone deficiency

Højby Rasmussen, M., Janukonyté, J., Klose, M., Marina, D., Tanvig, M., Nielsen, L.F., Höybye, C., Andersen, M., Feldt-Rasmussen, U., Sandahl Christiansen, J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

78

PO3-19: IGF-1 receptor C terminal tail phosphorylation on Y1250 in cancer cells

O Shea, S.P., Fernández, I., Kelly, G.M., O’ Connor, R.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 458 KB

english, 2014

79

PO2-20: Safety evaluation of long-term recombinant growth hormone (rGH) treatment in paediatric patients: interim analysis of NordiNet® International Outcome Study (IOS)

Sävendahl, L., Pournara, E., Tønnes Pedersen, B., Blankenstein, O.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

80

PO4-8: Subclinical hypothyroidism is associated with low IGF-I levels and decreased growth velocity

Bellini, H., Maciel, L.M., Custodio, R.J., Milani, S.S., Paula, M.S., Antonini, S.R., Liberatori, R.D., Martinelli, C.E.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

81

PO2-25: Assessment of hydration based on bioelectrical impedance analysis (BIA) and arm muscle area (AMA) in treatment-naïve adult patients with growth hormone deficiency (GHD)

Jørgensen, J.O.L., Tønnes Pedersen, B., Pournara, E., Høybye, C.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 449 KB

english, 2014

82

OR2-3: The Cardin-Weintraub Motif present in IGFBP-2 is required for growth and function of the mouse brain

Schindler, N., Mayer, J., Kirschstein, T., Saenger, S., Gimsa, U., Brenmoehl, J., Ohde, D., Zeissler, A., Russo, V., Metzger, F., Hoeflich, A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 437 KB

english, 2014

83

Plenary Lectures

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 545 KB

english, 2014

84

SY2-1: Insulin-like growth factor 2 mRNA binding proteins (IMP/IGF2BP) as mRNA safe houses in cancer and development

Christiansen, J., Jønson, L., Vikesaa, J., Hansen, T.v.O., Nielsen, F.C.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 458 KB

english, 2014

85

OR1-4: Successful GH treatment for severe growth failure in pediatric patients with anorexia nervosa

Fjellestad-Paulsen, A., Bargiacchi, A., Doyen, C., Raverdy, C., Carel, J.-C., Le Heuzey, M.-F., Leger, J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 445 KB

english, 2014

86

PO2-12: Development and characterization of manufacturing process of MOD-4023, a long acting human growth hormon to support clinical and commercial supply

Hershkovitz, O., Moschovich, L., Yana Felikman, Y., Guy, R., Fima, E.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 446 KB

english, 2014

87

GP2-7: The IGF/IGFR pathway regulates axial patterning during early neural development in mammal

Takata, N., Sakakura, E., Kasukawa, T., Eiraku, M., Sasai, Y.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

88

PO2-26: Pharmacokinetic (PK) and pharmacodynamic (PD) modeling of MOD-4023 (a long-acting hGH-CTP) in adults and growth hormone (GH)-deficient children

Fisher, D., Koren, R., Amitzi, L., Hershkovitz, O., Hart, G.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 449 KB

english, 2014

89

PO3-18: Lipopolysaccharide (LPS) treatment increased the protein levels of GKAP42 (42-kDa cGMP-dependent protein kinase anchoring protein) followed by inhibition of insulinmediated glucose transporter (GLUT) 4 translocation to the plasma membrane and glucose uptake in adipocytes

Yu, B.-C., Ando, Y., Obata, Y., Takenaka, A., Chida, K., Hakuno, F., Takahashi, S.-I.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

90

OR4-2: Growth hormone is a more potent growth stimulating hormone than IGF-I: clinical perspective

Laron, Z., Kauli, R., Iluz, M., Samuel, K., Silbergeld, A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 450 KB

english, 2014

91

PO2-11: Evidence for truncated somatostatin receptor 5 modulation of therapy response to somatostatin analogues in two patients with acromegaly and severe headache

Marina, D., Burman, P., Klose, M., Casar-Borota, O., Luque, R.M., Castaño, J.P., Feldt-Rasmussen, U.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

92

PO3-7: Growth hormone addition to medium in HepG2 cell culture: influence on IGF-I and IGF-II production

Knaack, H., Mense, K., Piechotta, M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

93

OR5-5: Autocrine hGH stimulated miRNA 96-182-183 cluster promotes epithelial-mesenchymal transition and invasion in breast cancer

Zhang, W., Qian, P., Zhang, X., Zhang, M., Wang, H., Wu, M., Kong, X., Tan, S., Ding, K., Perry, J.K., Wu, Z., Cao, Y., Lobie, P.E., Zhu, T.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 437 KB

english, 2014

94

PO2-10: Growth hormone treatment: case studies in Dr Soetomo Hospital

Rochmah, N., Faizi, M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 435 KB

english, 2014

95

OR8-6: The anti-IGF signaling agents increase the efficacy of Trabectedin in Ewing sarcoma

Garofalo, C., Amaral, A.T., Uboldi, S., Mancarella, C., Frapolli, R., Manara, M.C., Ordóñez, J.L., Belfiore, A., Picci, P., Hassan, B., De Alava, E., D’Incalci, M., Scotlandi, K.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

96

PO3-8: Understanding and targeting the IGFBP-3/IGFBP-3R system in obesity related disorders: IGFBP-3R agonists as preventive and therapeutic interventions for obesity-induced IR and T2DM

Cai, Q., Oh, Y.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

97

PO4-3: Serum levels of insulin-like growth factor I (IGF-I) and insulin-like growth factor binding protein 3 (IGFBP-3) in women with cervical cancer

Cho, D.H., Kim, M.S.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

98

PO2-1: The pathogenesis of anti-PIT-1 antibody syndrome - the involvement of PIT-1-reactive cytotoxic T lymphocytes

Bando, H., Iguchi, G., Fukuoka, H., Matsumoto, R., Suda, K., Nishizawa, H., Takahashi, M., Tojo, K., Takahashi, Y.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 437 KB

english, 2014

99

GP4-6: Effects of GH/IGF-I axis on retinal vascular morphology: retinal vascular morphology in Laron syndrome

Sekeroglu, H.T., Kadayifcilar, S., Kasim, B., Arslan, U., Ozon, Z.A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

100

GP3-1: Growth hormone (GH) replacement has a beneficial effect on glycosylated haemoglobin (HbA1c) levels in adult patients with GH deficiency (GHD) enrolled in the NordiNet® International Outcome Study (IOS)

Weber, M.M., Tønnes Pedersen, B., Pournara, E., Christiansen, J.S.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 444 KB

english, 2014

101

PO2-21: Growth hormone deficiency amongst nasopharyngeal cancer survivors

Ratnasingam, J., Karim, N., Paramasivam, S., Ibrahim, L., Lim, L.L., Jalaludin, A., Tan, A., Vethakkan, S., Chan, S.P.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

102

OR8-5: Novel mechanisms by which Nedd4-IRS-2 complexes enhance IGF-I signals, and their roles in IGF-I action in prostate cancer cell proliferation

Fukushima, T., Yoshihara, H., Furuta, H., Hakuno, F., Saeki, Y., Nakatsu, Y., Kamata, H., Asano, T., Takahashi, S.-I.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 459 KB

english, 2014

103

Author index

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 598 KB

english, 2014

104

OR8-3: Role of deubiquitinase USP7 in signalling through IGF-1R

Worrall, C., Suleymanova, N., Yoshihara, H., Hakuno, F., Takahashi, S.-I., Girnita, A., Girnita, L.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 448 KB

english, 2014

105

PO2-6: Autocrine human growth hormone (hGH) promotes metabolic reprogramming in breast cancer cells to adapt to available glucose

Banerjee, A., Pandey, V.K., Lau, A.Y.C., Lobie, P.E.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 435 KB

english, 2014

106

PO2-9: Growth without growth hormone

Rochmah, N., Faizi, M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 446 KB

english, 2014

107

OR1-1: GH treatment modulates mortality in adult onset GH deficiency and a discordant socio-economic status is apparent

Stochholm, K., Berglund, A., Gravholt, C., Christiansen, J.S.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 563 KB

english, 2014

108

OR8-2: Insulin-like growth factor receptor inhibition in mammary epithelium enhances Wnt1- mediated tumors, canonical Wnt signaling and IGF-II/insulin-receptor A expression

Wood, T.L., Rota, L.M., Albanito, L., Shin, M.E., Goyeneche, C.L., Shushanov, S., Gallagher, E.J., Leroith, D., Lazzarino, D.A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 460 KB

english, 2014

109

OR8-1: Insulin receptor substrate (IRS)-1 interacts with protein arginine methyltransferase 5 (PRMT5), emerging as a novel regulator of alternative pre-mRNA splicing

Ozoe, A., Narita, Y., Fukushima, T., Kataoka, N., Ito, A., Yoshida, M., Chida, K., Asano, T., Hakuno, F., Takahashi, S.-I.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 449 KB

english, 2014

110

GP1-3: Role of growth hormone (GH) signaling pathways in the development of atherosclerosis

Ishikawa, M., Toyomura, J., Kuboki, K., Morita, T., Tominaga, N., Hirose, T., Minami, S., Yoshino, G.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 527 KB

english, 2014

111

OR4-5: IGF bioactivity in sera and pleural effusions from patients suspected of lung cancer

Espelund, U., Hjortebjerg, R., Folkersen, B., Rasmussen, T.R., Oxvig, C., Frystyk, J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 444 KB

english, 2014

112

PO2-23: Growth and puberty of children with congenital isolated growth hormone deficiency

Smuel, K., Kauli, R., Laron, Z.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

113

PO2-3: Multiple doses of a reversible albumin-binding growth hormone derivative demonstrate no differences in PK and PD between Japanese and non-Asian subjects

Højby Rasmussen, M., Olsen, M.W.B., Alifrangis, L., Klim, S., Suntum, M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

114

OR3-4: GH activated signal transducer and activator of transcription 5 is required for induction of beige fat in inguinal white adipose tissue

Nelson, C.N., Ieremia, M., Constantin, L., List, E.O., Kopchick, J.J., Waters, M.J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 642 KB

english, 2014

115

GP4-1: Loss of PI 3-kinase-binding protein PI3KAP/XB130 suppresses thyroid function and induces enlargement of thyroid glands in mice

Yamanaka, D., Hakuno, F., Minami, S., Hashimoto, K., Suzuki, K., Chida, K., Takahashi, S.-I.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

116

GP3-4: Discordance of post-surgical nadir GH during OGTT and serum IGF-I levels in patients with acromegaly

Fukuda, I., Hizuka, N., Muraoka, T., Amano, K., Kawamata, T., Okada, Y., Ichihara, A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

117

OR5-2: Rabbits are a suitable animal model for the pre-clinical development of growth hormone agonists and antagonists

Bielohuby, M., Zarkesh-Esfahani, S.H., Manolopoulou, J., Khorasgani, M.T., Aghili, Z.S., Wilkinson, I.R., Ross, R.J., Bidlingmaier, M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 448 KB

english, 2014

118

PO4-2: Variations in growth in relation to IGF-I levels in children born very preterm and target height influences from birth to 3-years of age

Kistner, A., Hellgren, G., Niklasson, A., Sigurdsson, J., Löfqvist, C., Hellström, A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 455 KB

english, 2014

119

OR7-7: Pasireotide LAR provides superior efficacy over octreotide LAR and lanreotide ATG in patients with inadequately controlled acromegaly: a phase III, multicenter, randomized study (PAOLA)

Fleseriu, M., Gadelha, M., Bronstein, M.D., Brue, T., Coculescu, M., Guitelman, M., Pronin, V., Raverot, G., Shimon, I., Fleck, J., Aout, M., Pedroncelli, A.M., Colao, A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 462 KB

english, 2014

120

PO3-15: Regulation of IGF-1 at the transcription level by IGFBP-1

Ansurudeen, I., Brismar, K.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

121

OR8-4: A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies

Sun, J., Li, W., Sun, Y., Wang, H., Cui, J., Wang, G., Wei, Z., Hoffman, A., Hu, J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 448 KB

english, 2014

122

PO3-5: Developing predictive determinants of IGF/INS targeted therapies in ovarian cancer patient tumors and primary tumorgrafts

Becker, M., Hou, X., Haluska, P.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 444 KB

english, 2014

123

PO2-16: IGF-1 as nutritional marker

Kim, J.H., Lee, J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

124

PO2-15: Insulin tolerance test and GHRH plus arginine in the reassessment of pituitary function at adult height achievement

Di Iorgi, N., Salerno, M.C., Cappa, M., Loche, S., Radetti, G., Capaldo, D., Allegri, A., Napoli, F., Calcagno, A., Iovovich, O.B., Noli, S., Parodi, S., Maghnie, M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

125

OR6-1: Dicarba modification of insulin peptides results in lower mitogenic activity signaled via IGF-1R and IR than insulin

Ong, S.C., van Lierop, B., Delaine, C., Andrikopoulos, S., Robinson, A., Forbes, B.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 440 KB

english, 2014

126

SY1-7: Abuse of growth hormone

Strasburger, C.J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 447 KB

english, 2014

127

OR6-5: Sexual dimorphism of insulin like growth factor I in exercise

Munive Herrera, V.A., Torres Aleman, I.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

128

OR7-3: Safety and efficacy results of a 6 month, randomized, multicenter trial of a novel long-acting rhGH (VRS-317) in naïve to treatment, pre-pubertal children with GH deficiency

Bright, G.M., Moore, W.V., Nguyen, H.Q., Kletter, G.B., Miller, B.S., Van Meter, Q., Humphriss, E., Cleland, J.L.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 459 KB

english, 2014

129

GP1-4: Mortality in patients with non-functioning pituitary adenoma with and without growth hormone replacement therapy. A case-controlled study in more than 400 patients

Trimpou, P., Johannsson, G., Andersson, E., Nilsson, A.G., Olsson, D.S.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 448 KB

english, 2014

130

GP2-4: Insulin-like growth factor binding protein (IGFBP)-1 and its RGD domain: favorable in vivo actions in glucose regulation

Haywood, N., Yuldasheva, N., Aziz, A., Smith, J., Cordell, P., Kearney, M., Wheatcroft, S.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 448 KB

english, 2014

131

Associate Editors

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 453 KB

english, 2014

132

PO3-1: Molecular, biochemical, histological, and phylogenetic characterizations of insulin-like peptides and insulin/insulinlike growth factor (IGF)-I receptors in rotifers

Ozaki, Y., Kaneko, G., Hakuno, F., Takahashi, S.-I., Mark Welch, D.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

133

GP4-5: Circulating levels of insulin-like growth factor-1(IGF-I)/insulin-like growth factor binding protein-3 (IGFBP-3) in obese patients: the state of type 2 diabetes

Kim, M.S., Kim, S.-Y., Lee, D.-Y.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 461 KB

english, 2014

134

PO2-17: Soluble alpha-Klotho and vitamin D in acromegaly

Bolanowski, M., Jawiarczyk-Przybyłowska, A., Kolackov, K.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

135

GP2-5: Hyperglycaemia induces chemo-resistance of breast cancer cells via regulating IGFBP-2/oestrogen receptor (ERa) interactions: role of ERa phosphorylation

Zeng, L., Holly, J.M., Arshad, A., Bahl, A., Hathwar, S., Perks, C.M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 448 KB

english, 2014

136

OR4-6: The expression of insulin-like growth factor type 1 receptor (IGF1R) is increased in obese children

Ricco, R.C., Custodio, R.J., Atique, P.V., Liberatore, R.D., Ricco, R.G., Martinelli, C.E.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 461 KB

english, 2014

137

PO3-16: Altered mouse adipose tissue IGF-1 expression influences glucose control

Trost, J., Alcaniz Rolli, J., Brockmann, G.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

138

PO4-9: Complex tissue-specific epigenotypes in Russell Silver syndrome with 11p15 ICR1 hypomethylation: major consequences for the diagnosis

Azzi, S., Blaise, A., Steunou, V., Thibaud, N., Le Bouc, Y., Netchine, I.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 457 KB

english, 2014

139

PO5-2: Serum prolactin level in chronic kidney disease

Vasilkova, O., Szhmailik, M., Zekenova, K., Mokhort, T.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 438 KB

english, 2014

140

PO3-13: ADLib® system: a versatile antibody discovery platform

Hashimoto, S., Uchiki, T., Moriyama, S., Sasakura, Y., Tsuji, T., Konakahara, S., Nakazaki, Y., Hani, T., Asagoshi, K., Sawada, A., Takaiwa, A., Yabuki, T., Murakami, K.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

141

PO3-6: Serum concentrations of IGF-I and IGF-II proceed in a reciprocal manner during a physiological cycle and maternal IGFBP-4 concentration was lower in pregnant than in not pregnant dairy heifers during early pregnancy

Meyerholz, M., Mense, K., Linden, M., Knaack, H., Wirthgen, E., Hoeflich, A., Lietzau, M., Richard, C., Raliou, M., Sandra, O., Hoedemarker, M., Piechotta, M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 444 KB

english, 2014

142

PO3-14: Activated STAT3 as a possible resistance mechanism to the anti-tumour effects of an anti-IGF-II neutralising antibody in hepatocellular carcinoma

Greenall, S.A., Johns, T.G., Adams, T.E.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

143

OR3-2: GH enhances spine density in amygdalar neurons

Gisabella, B., Brophy, J., Goosens, K.A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 625 KB

english, 2014

144

GP3-3: The diagnostic accuracy of pegvisomant-primed glucagon stimulation test (PV-GST) compared to insulin tolerance (ITT) and glucagon stimulation (GST) tests in evaluating adult growth hormone (GH) reserve

Yuen, K.C.J., Frystyk, J., Rhoads, S.A., Legg, S.E., Bidlingmaier, M.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

145

PO3-10: Constitutive IRS1 expression causes cell competition, leading to defect in myogenic differentiation

Hakuno, F., Yoneyama, Y., Ozoe, A., Takahashi, S.-I.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 441 KB

english, 2014

146

GP4-2: Effects of heparin administration on the generation of IGFBP-4 fragments during PCI treatment of ST-elevation myocardial infarction patients

Hjortebjerg, R., Lindberg, S., Jensen, J.S., Oxvig, C., Bjerre, M., Frystyk, J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 461 KB

english, 2014

147

PO2-19: Growth hormone therapy in a child with Kearns Sayre syndrome and chronic kidney disease

Sng, A., Loke, K.Y., Lim, Y., Ho, C.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 455 KB

english, 2014

148

OR5-3: A GH antagonist fusion with GH binding protein is biologically active, shows delayed clearance and inhibits growth in a rabbit model

Wilkinson, I., Pradhananga, S., Sayers, J., Artymiuk, P., Phipps, M., Ross, R.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 460 KB

english, 2014

149

OR7-8: A phase II randomised, open-label, parallelgroup study of the safety, tolerability, pharmacokinetics and efficacy of two subcutaneous dosing regimens of ATL1103 in adult patients with acromegaly

Trainer, P.J., Newell-Price, J., Ayuk, J., Aylwin, S., Drake, W.M., Rees, A., Chanson, P., Brue, T., Webb, S.M., Fajardo, C., Aller, J., McCormack, A., Torpy, D.J., Tachas, G., Atley, L.M., Bidlingmai

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 449 KB

english, 2014

150

OR3-1: Spatial learning, memory and signaling cross-talk: genomic and behavioral analysis in wild type versus GH modified (bGH & GHA) mice

Basu, A., Kopchick, J.J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 714 KB

english, 2014

151

OR7-5: Safety, tolerability, pharmacokinetics and pharmacodynamics of TV-1106, a new long-acting treatment for growth hormone deficiency

CohenBarack, O., Sakov, A., Rasamoelisolo, M., Bassan, M., Brown, K., Spiegelstein, O.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

152

OR5-1: Mechanism of activation of JAK2 by growth hormone

Waters, M.J., Brooks, A.J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 448 KB

english, 2014

153

PO1-1: Analysis of chimeric mice using growth hormone receptor gene disrupted (GHRKO) derived bone-marrow to investigate the role of GH signaling in the infiltration of proinflammatory macrophages in adipose tissue

Herpy, J., Okada, S., Benencia, F., Kopchick, J.J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 527 KB

english, 2014

154

GP4-7: ProIGF-II not matureIGF-II promotes estrogen independent breast cancer growth and metastasis in a SCID and Nude mouse model: differential signallng mechanisms thru IGF and Insulin receptors and phosphorylation/activation of estrogen and progesterone receptors

Jian, T., Kalla-Singh, S., Radhakrishnan, V.K., De León, M.A., DeLeon, D.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 454 KB

english, 2014

155

PO2-13: Human growth hormone and human prolactin possess autocrine roles in hepatocellular carcinoma

Zhang, M., Kong, X., Wu, Z., Yan, Y., Pandey, V., Wu, W., Lu, X., Zhang, W., Li, G., Tan, S., Zhang, D., Perry, J.K., Lobie, P.E., Zhu, T.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 435 KB

english, 2014

156

OR5-6: Amplified stem/progenitor cells in a mouse model of prostate tumorigenesis induced by autocrine prolactin

Sackmann Sala, L., Mosquera-Garrote, N., Chiche, A., Pourmir, I., Boutillon, F., Goffin, V.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 451 KB

english, 2014

157

GP1-1: Growth hormone targets expression of specific lipolytic genes to promote lipolysis of white adipose tissue

Law, Y.Y., Romero, C., Radovick, S.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 555 KB

english, 2014

158

PO2-14: Genetic markers of insulin resistance are associated with growth hormone response in short SGA children - the North European SGA study (NESGAS)

Jensen, R.B., Thankamony, A., Day, F., Kirk, J., Donaldson, M., Ivarsson, S.-A., Söder, O., Roche, E., Hoey, H., Juul, A., Ong, K.K., Dunger, D.B.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 435 KB

english, 2014

159

GP2-3: The role of the insulin receptor in breast cancer progression

Rostoker, R., Abelson, S., Bitton-Worms, K., Genkin, I., Ben-Shmuel, S., Caspi, A., Tzukerman, M., LeRoith, D.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 458 KB

english, 2014

160

SY1-6: Growth hormone and sarcopenia - future aspects

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 447 KB

english, 2014

161

OR6-3: Early postnatal nutritional programming of growth involves GHRH neurons axon growth stimulation by leptin & IGF-I

Decourtye, L., Mire, E., Clemessy, M., Heurtier, V., Godefroy, D., Cong, R., Ledent, T., Robinson, I., Reaux-Le Goazigo, A., Mollard, P., Meaney, M., Garel, S., Le Bouc, Y., Kappeler, L.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 509 KB

english, 2014

162

PO3-12: Balancing the IGF-1R-Mdm2-p53 axis as novel therapeutic strategy in skin melanoma

Girnita, A., Worall, C., Candrea, E., Takahashi, S.-I., Girnita, L.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 441 KB

english, 2014

163

GP3-6: Mixed effects PK/PD modelling of NNC0195-0092 - a noncovalent albumin binding growth hormone derivative in the hypophysectomised rat

Thygesen, P., Agersø, H., Fels, J.J., Johansen, N.L.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

164

OR8-8: Serum IGF-I measured longitudinally during pre-school years - relation to gender, body size, and nutrition such as essential fatty acids and vitamin D

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 445 KB

english, 2014

165

OR2-2: The mitochondrial peptide humanin has fasting mimetic activity leading to suppression of circulating IGF-I and increases in IGFBP-1 levels

Xiao, J., Wan, J., Mehta, H., Lue, Y.-H., Jia, Y., Swerdloff, R., Wang, C., Cohen, P.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 594 KB

english, 2014

166

GP1-2: Autocrine human growth hormone suppression of E-CADHERIN via p44/42 MAPK promotes epithelial-tomesenchymal transition (EMT) of colorectal carcinoma cells

Wang, J., Wu, Z., Pandey, V., Chen, Y., Zhu, T., Lobie, P.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 555 KB

english, 2014

167

GP2-6: Differential effects of IGFBP-6 on migration of two ovarian cancer cell lines

Bach, L., Yang, Z.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 459 KB

english, 2014

168

GP1-5: Presurgical somatostatin analogue versus direct surgery for newly-diagnosed acromegaly patients: a systematic review and meta-analysis, assessing clinical evidence using the GRADE system

Nunes, V.S., Correa, J.M., Puga, M.E., Silva, E.M., Boguszewski, C.L.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 448 KB

english, 2014

169

PO5-1: Clinical relevance of serum prolactin level in perimenopausal women with metabolic syndrome

Pchelin, I., Hudiakova, N., Shishkin, A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 438 KB

english, 2014

170

GP3-5: Thyroid hormone activation regulates exercise induced growth hormone release

Ignacio, D.L., Silvestre, D.H.S., Cavalcanti-de-Albuquerque, J.P., Neto, R.A.L., Ferreira, A.C.C., Carvalho, D.P., Werneck-de-Castro, J.P.S.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

171

PO3-4: IGF-1-regulated PDLIM2 protein is required for epithelial to mesenchymal transition (EMT) and transcription factor stability

Cox, O.T., Bowe, R.A., Tresse, E., O’Connor, R.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 444 KB

english, 2014

172

SY1-2: Dosing and Monitoring GH Treatment in GH Deficient Children

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 555 KB

english, 2014

173

OR1-2: Impairment of anaerobic capacity in adults with growth hormone deficiency

Chikani, V., Cuneo, R., Hickman, I., Ho, K.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 563 KB

english, 2014

174

GP1-6: Metabolic requirements to sustain NEFA and glucose homeostasis overrides the role of growth hormone in promoting rapid linear growth in hyperphagic MC4RKO mice

Tan, H.Y., Huang, L., Veldhuis, J.D., Cowley, M., Steyn, F.J., Chen, C.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 444 KB

english, 2014

175

PO2-7: Assessing the impact of storage flexibility on daily life for patients and caregivers taking/administering growth hormone (GH)

Kappelgaard, A.-M., Metzinger, C.P., Signer-Romero, K., Schnabel, D.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 435 KB

english, 2014

176

SY2-2: The IRS proteins: determinants of IGF-1R signaling and tumor metabolism

Shaw, L., Landis, J., Zhu, S., Janusis, J., Mercado-Matos, J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 440 KB

english, 2014

177

OR3-3: Liver-specific (LiGHRKO) and fat-specific (FaGHRKO) growth hormone receptor gene disrupted mice demonstrate paradoxical longevity and provide evidence for GH stimulated liver/adipose tissue-crosstalk

List, E.O., Berryman, D.E., Jara, A., Ikeno, Y., Miller, R.A., Kopchick, J.J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 625 KB

english, 2014

178

OR2-6: Cyclic glycine-proline is a regulator that dynamically controls IGF-1 homeostasis through altering IGF-1 binding to IGFBP3

Guan, J., Gluckman, P., Yang, P., Wen, J., Krissansen, G., Sun, K., Zhou, Y., McMahon, C., Shorten, P., Wake, G., Phillips, G., Thomas, M.F., Moon, S., Liu, D.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 440 KB

english, 2014

179

Behavioural phenotyping of male growth hormone-releasing hormone (GHRH) knockout mice

Leone, Sheila, Shohreh, Rugia, Manippa, Fabio, Recinella, Lucia, Ferrante, Claudio, Orlando, Giustino, Salvatori, Roberto, Vacca, Michele, Brunetti, Luigi

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 496 KB

english, 2014

180

Autosomal recessive form of isolated growth hormone deficiency is more frequent than the autosomal dominant form in a Brazilian cohort

Lido, Andria C.V., França, Marcela M., Correa, Fernanda A., Otto, Aline P., Carvalho, Luciani R., Quedas, Elisangela P.S., Nishi, Mirian Y., Mendonca, Berenice B., Arnhold, Ivo J.P., Jorge, Alexander

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 999 KB

english, 2014

181

Impact of moderate interval exercise versus supine rest on the pharmacokinetics and pharmacodynamic profiles of subcutaneously administered growth hormone in adult growth hormone deficient patients

Janukonytė, J., Parkner, T., Lauritzen, T., Christiansen, J.S., Frystyk, J., Pedersen, H.S., Laursen, T.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 375 KB

english, 2014

182

Circulating asymmetric dimethylarginine and lipid profile in pre-pubertal children with growth hormone deficiency: Effect of 12-month growth hormone replacement therapy

De Marco, S., Marcovecchio, M.L., Caniglia, D., De Leonibus, C., Chiarelli, F., Mohn, A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 253 KB

english, 2014

183

Long-term effects of growth hormone replacement therapy on liver function in adult patients with growth hormone deficiency

Matsumoto, Ryusaku, Fukuoka, Hidenori, Iguchi, Genzo, Nishizawa, Hitoshi, Bando, Hironori, Suda, Kentaro, Takahashi, Michiko, Takahashi, Yutaka

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 618 KB

english, 2014

184

IGF-I sensitivity in Silver–Russell syndrome with IGF2/H19 hypomethylation

Iliev, D.I., Kannenberg, K., Weber, K., Binder, G.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 399 KB

english, 2014

185

Editorial Board

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 60 KB

english, 2014

186

Lactate activates the somatotropic axis in rats

Salgueiro, Rafael Barrera, Peliciari-Garcia, Rodrigo A., do Carmo Buonfiglio, Daniella, Peroni, Cibele Nunes, Nunes, Maria Tereza

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 306 KB

english, 2014

187

Mass spectrometric characterization of a biotechnologically produced full-length mechano growth factor (MGF) relevant for doping controls

Thevis, Mario, Thomas, Andreas, Geyer, Hans, Schänzer, Wilhelm

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 306 KB

english, 2014

188

IGF-I at 9 and 36months of age — relations with body composition and diet at 3years — the SKOT cohort

Ejlerskov, K.T., Larnkjaer, A., Pedersen, D., Ritz, C., Mølgaard, C., Michaelsen, K.F.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 336 KB

english, 2014

189

Motor and memory testing of long-lived pregnancy-associated plasma protein—A knock-out mice

Mason, Emily J., Grell, Jacquelyn A., West, Sally A., Conover, Cheryl A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 362 KB

english, 2014

190

Sexual dimorphism in growth and insulin-like growth factor-I in children with type 1 diabetes mellitus

Bizzarri, Carla, Benevento, Danila, Giannone, Germana, Bongiovanni, Marzia, Anziano, Marco, Patera, Ippolita Patrizia, Cappa, Marco, Cianfarani, Stefano

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 228 KB

english, 2014

191

Corneal endothelial cell density and morphology in patients with acromegaly

Hatipoglu, Esra, Arici, Ceyhun, Arslan, Osman Sevki, Dikkaya, Funda, Sultan, Pinar, Kadioglu, Pinar, Gundogdu, Sadi

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 293 KB

english, 2014

192

A novel gross indel in the growth hormone releasing hormone receptor gene of Indian IGHD patients

Kale, Shantanu, Budyal, Sweta, Kasaliwal, Rajeev, Shivane, Vyankatesh, Raghavan, Vijaya, Lila, Anurag, Bandgar, Tushar, Shah, Nalini

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 1.61 MB

english, 2014

193

Nanotopology potentiates growth hormone signalling and osteogenesis of mesenchymal stem cells

Wang, Jessie R., Ahmed, S. Faisal, Gadegaard, Nikolaj, Meek, R.M. Dominic, Dalby, Matthew J., Yarwood, Stephen J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 1.40 MB

english, 2014

194

Column chromatographic characterization of complex formation of pro-IGF-II isoforms with acid labile subunit and IGF-binding proteins associated with non-islet cell tumour induced hypoglycaemia

van Veggel, K.M., Huits, R.M.H.G., Donker, G.H., Lentjes, E.G.W.M., van Doorn, J.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 535 KB

english, 2014

195

Growth hormone replacement therapy in Costello syndrome

Triantafyllou, Panagiota, Christoforidis, Athanasios, Vargiami, Euthymia, Zafeiriou, Dimitrios I.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 876 KB

english, 2014

196

Pregnancy-associated plasma protein-A expression in human breast cancer

Mansfield, Aaron S., Visscher, Daniel W., Hart, Steven N., Wang, Chen, Goetz, Matthew P., Oxvig, Claus, Conover, Cheryl A.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 633 KB

english, 2014

197

The complex relationship between obesity and the somatropic axis: The long and winding road

Savastano, Silvia, Di Somma, Carolina, Barrea, Luigi, Colao, Annamaria

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 553 KB

english, 2014

198

Editor Emeritus

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 453 KB

english, 2014

199

Editorial Board

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 453 KB

english, 2014

200

Editor-in-Chief (Europe & RoW)

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 453 KB

english, 2014

201

Editor-in-Chief (The Americas)

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 523 KB

english, 2014

202

Editorial Board

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 57 KB

english, 2014

203

OR1-6: Combination medical therapy for acromegaly: the ACROSTUDY experience

Strasburger, C., Hey-Hadavi, J., Akerblad, A.-C., Mattsson, A.F., Koltowska-Häggström, M., Biller, B.M.K.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 595 KB

english, 2014

204

In memory of Francesco Maria Minuto

Ferone, Diego, Boschetti, Mara, Arvigo, Marica, Fazzuoli, Laura, Giusti, Massimo, del Monte, Patrizia

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 163 KB

english, 2014

205

Editorial Board

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 186 KB

english, 2014

206

Copyright

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 448 KB

english, 2014

207

SY1-4: Dosing and monitoring GH treatment in Turner syndrome

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 609 KB

english, 2014

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