Volume 56; Issue 1-2

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Il Farmaco
Volume 56; Issue 1-2

Il Farmaco

Volume 56; Issue 1-2

1

Microbial fermentation-derived inhibitors of efflux-pump-mediated drug resistance

May D. Lee, Jorge L. Galazzo, Andrew L. Staley, Julie C. Lee, Mark S. Warren, Hans Fuernkranz, Suzanne Chamberland, Olga Lomovskaya, George H. Miller

Journal:

Year:

2001

Language:

english

File:

PDF, 204 KB

english, 2001

2

Ligands for expression cloning and isolation of GABAB receptors

Wolfgang Froestl, Bernhard Bettler, Helmut Bittiger, Jakob Heid, Klemens Kaupmann, Stuart J. Mickel, Dietrich Strub

Journal:

Year:

2001

Language:

english

File:

PDF, 134 KB

english, 2001

3

Piperidine renin inhibitors: from leads to drug candidates

H.P. Märki, A. Binggeli, B. Bittner, V. Bohner-Lang, V. Breu, D. Bur, Ph. Coassolo, J.P. Clozel, A. D'Arcy, H. Doebeli, W. Fischli1, Ch. Funk, J. Foricher, T. Giller, F. Grüninger, A. Guenzi, R. Gülle

Journal:

Year:

2001

Language:

english

File:

PDF, 221 KB

english, 2001

4

A1 adenosine receptors and their ligands: overview and recent developments

Christa E Müller

Journal:

Year:

2001

Language:

english

File:

PDF, 140 KB

english, 2001

5

Metabotropic glutamate receptors: structure and new subtype-selective ligands

Roberto Pellicciari, Gabriele Costantino, Maura Marinozzi, Antonio Macchiarulo, Emidio Camaioni, Benedetto Natalini

Journal:

Year:

2001

Language:

english

File:

PDF, 116 KB

english, 2001

6

New developments in anti-HIV chemotherapy

Journal:

Year:

2001

Language:

english

File:

PDF, 114 KB

english, 2001

7

Discovery and characterization of non-competitive antagonists of group I metabotropic glutamate receptors

Fabrizio Gasparini, Philipp Floersheim, Peter Josef Flor, Micheline Heinrich, Werner Inderbitzin, David Ott, Adriana Pagano, Christine Stierlin, Natacha Stoehr, Ivo Vranesic, Rainer Kuhn

Journal:

Year:

2001

Language:

english

File:

PDF, 788 KB

english, 2001

8

A new class of cytotoxic DNA minor groove binders: α-halogenoacrylic derivatives of pyrrolecarbamoyl oligomers

Journal:

Year:

2001

Language:

english

File:

PDF, 194 KB

english, 2001

9

Molecular diversity: how we measure it? Has it lived up to its promise?

Yvonne C. Martin

Journal:

Year:

2001

Language:

english

File:

PDF, 55 KB

english, 2001

10

Lipoprotein-associated PLA2 inhibition — a novel, non-lipid lowering strategy for atherosclerosis therapy

Colin A Leach, Deirdre M.B Hickey, Robert J Ife, Colin H Macphee, Stephen A Smith, David G Tew

Journal:

Year:

2001

Language:

english

File:

PDF, 173 KB

english, 2001

11

Binding of polyamine-containing toxins in the vestibule of the nicotinic acetylcholine receptor ion channel

M.Gabriele Bixel, Michael Krauss, Christoph Weise, Maria L. Bolognesi, Michela Rosini, Peter N.R. Usherwood, Carlo Melchiorre, Ferdinand Hucho

Journal:

Year:

2001

Language:

english

File:

PDF, 65 KB

english, 2001

12

Novel bone antiresorptive agents that selectively inhibit the osteoclast V-H+-ATPase

Carlo Farina, Stefania Gagliardi, Guy Nadler, Marcel Morvan, Carlo Parini, Pietro Belfiore, Luciano Visentin, Maxine Gowen

Journal:

Year:

2001

Language:

english

File:

PDF, 223 KB

english, 2001

13

Characterisation of inter- and intra-molecular interactions of the dengue virus RNA dependent RNA polymerase as potential drug targets

Subhash G. Vasudevan, Magnus Johansson, Andrew J. Brooks, Lyndon E. Llewellyn, David A. Jans

Journal:

Year:

2001

Language:

english

File:

PDF, 156 KB

english, 2001

14

Allosteric modulation of G protein-coupled receptors

Ad IJzerman, Angeliki Kourounakis, Pieter van der Klein

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Year:

2001

Language:

english

File:

PDF, 80 KB

english, 2001

15

Applications of NMR screening in the pharmaceutical industry

Michael Shapiro

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Year:

2001

Language:

english

File:

PDF, 130 KB

english, 2001

16

Discovery of gemifloxacin (Factive, LB20304a): a quinolone of new a generation

Chang Yong Hong

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Year:

2001

Language:

english

File:

PDF, 92 KB

english, 2001

17

Prediction of drug toxicity

Mark T.D. Cronin

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Year:

2001

Language:

english

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PDF, 56 KB

english, 2001

18

The continuing evolution of the drug discovery process in the pharmaceutical industry

Emiliangelo Ratti, David Trist

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Year:

2001

Language:

english

File:

PDF, 147 KB

english, 2001

19

Selective δ opioid receptor agonists for inflammatory and neuropathic pain

Giulio Dondio, Silvano Ronzoni, Carlo Farina, Davide Graziani, Carlo Parini, Paola Petrillo, Giuseppe A.M Giardina

Journal:

Year:

2001

Language:

english

File:

PDF, 80 KB

english, 2001

20

Analogues of polyamine alkaloids and their synthetic advantages

Yi Li, Kasim Popaj, Martin Lochner, Herve Geneste, Roberta Budriesi, Alberto Chiarini, Carlo Melchiorre, Manfred Hesse

Journal:

Year:

2001

Language:

english

File:

PDF, 135 KB

english, 2001

21

Specific κ opioid receptor agonists

Giuseppe Ronsisvalle, Agostino Marrazzo, Lorella Pasquinucci, Orazio Prezzavento, Maria Pappalardo, Franco Vittorio

Journal:

Year:

2001

Language:

english

File:

PDF, 123 KB

english, 2001

22

Structurally related nucleotides as selective agonists and antagonists at P2Y1 receptors

Kenneth A. Jacobson, Stefano Moro, Carsten Hoffmann, Yong-Chul Kim, Hak Sung Kim, R.Gnana Ravi, T.Kendall Harden, José L. Boyer

Journal:

Year:

2001

Language:

english

File:

PDF, 160 KB

english, 2001

23

Selective adenosine A2A receptor antagonists

Ennio Ongini, Angela Monopoli, Barbara Cacciari, Pier Giovanni Baraldi

Journal:

Year:

2001

Language:

english

File:

PDF, 87 KB

english, 2001

24

Structure-based design of non-peptide HIV protease inhibitors

Arun K. Ghosh, Dongwoo Shin, Lisa Swanson, K. Krishnan, Hanna Cho, Khaja Azhar Hussain, D.Eric Walters, Louis Holland, Jim Buthod

Journal:

Year:

2001

Language:

english

File:

PDF, 98 KB

english, 2001

25

The 4-anilinoquinazoline class of inhibitors of the erbB family of receptor tyrosine kinases

William A. Denny

Journal:

Year:

2001

Language:

english

File:

PDF, 143 KB

english, 2001

26

Disease-modifying anti-osteoarthritic drugs: current therapies and new prospects around protease inhibition

Guillaume De Nanteuil, Bernard Portevin, Alain Benoist

Journal:

Year:

2001

Language:

english

File:

PDF, 136 KB

english, 2001

27

Physicochemical properties in pharmacokinetic lead optimization

Stefanie D. Krämer, Heidi Wunderli-Allenspach

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Year:

2001

Language:

english

File:

PDF, 107 KB

english, 2001

28

Recent advances in the field of quinolones

Makoto Takemura, Isao Hayakawa

Journal:

Year:

2001

Language:

english

File:

PDF, 111 KB

english, 2001

29

Preface

Giuseppe Ronsisvalle

Journal:

Year:

2001

Language:

english

File:

PDF, 33 KB

english, 2001