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1

Rationally designed inhibitors as tools for comparing the mechanism of squalene-hopene cyclase with oxidosqualene cyclase

Franca Viola, Maurizio Ceruti, Luigi Cattel, Paola Milla, Karl Poralla, Gianni Balliano

Journal:

Year:

2000

Language:

english

File:

PDF, 624 KB

english, 2000

2

Vinyl sulfide derivatives of truncated oxidosqualene as selective inhibitors of oxidosqualene and squalene-hopene cyclases

Maurizio Ceruti, Gianni Balliano, Flavio Rocco, Paola Milla, Silvia Arpicco, Luigi Cattel, Franca Viola

Journal:

Year:

2001

Language:

english

File:

PDF, 127 KB

english, 2001

3

Synthesis and biological activity of new lodoacetamide derivatives on mutants of squalene-hopene cyclase

Maurizio Ceruti, Gianni Balliano, Flavio Rocco, Alexander Jenhart, Georg E. Schulz, Francesco Castelli, Paola Milla

Journal:

Year:

2005

Language:

english

File:

PDF, 194 KB

english, 2005

4

Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase ofTrypanosoma cruziexpressed inSaccharomyces cerevisiae

Simonetta Oliaro-Bosso, Maurizio Ceruti, Gianni Balliano, Paola Milla, Flavio Rocco, Franca Viola

Journal:

Year:

2005

Language:

english

File:

PDF, 197 KB

english, 2005

5

In vitro metabolism of 2-(5-ethylpyridin-2-yl)benzimidazole

O. Caputo, G. Grosa, G. Balliano, F. Rocco, G. Biglino

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

1988

Language:

english

File:

PDF, 523 KB

english, 1988

6

Kinetic and Crystallographic Studies on Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi in Complex with Iodoacetate

Guido, Rafael, Balliano, Tatiane, Andricopulo, Adriano, Oliva, Glaucius

Journal:

Letters in Drug Design & Discovery

Year:

2009

Language:

english

File:

PDF, 195 KB

english, 2009

7

Preparação e caracterização de nanocompósitos poliméricos baseados em quitosana e argilo minerais

Fiori, Ana Paula Santos de Melo, Gabiraba, Victor Parizio, Praxedes, Ana Paula Perdigão, Nunes, Marcelo Ramon da Silva, Balliano, Tatiane L., Silva, Rosanny Christhinny da, Tonholo, Josealdo, Ribeiro,

Journal:

Polímeros Ciência e Tecnologia

Year:

2014

File:

PDF, 1.75 MB

2014

8

Systematic analysis of yeast strains with possible defects in lipid metabolism

Daum, Günther, Tuller, Gabriele, Nemec, Tamara, Hrastnik, Cladia, Balliano, Gianni, Cattel, Luigi, Milla, Paola, Rocco, Flavio, Conzelmann, Aadreas, Vionnet, Christine, Kelly, Diane E., Kelly, Steven,

Journal:

Year:

1999

Language:

english

File:

PDF, 326 KB

english, 1999

9

Access of the Substrate to the Active Site of Yeast Oxidosqualene Cyclase: An Inhibition and Site-Directed Mutagenesis Approach

Simonetta Oliaro-Bosso, Tanja Schulz-Gasch, Gianni Balliano, Franca Viola

Journal:

Year:

2005

Language:

english

File:

PDF, 356 KB

english, 2005

10

Mechanism(s) of SWI/SNF-Induced Nucleosome Mobilization

Ning Liu, Angela Balliano, Prof. Dr. Jeffrey J. Hayes

Journal:

Year:

2011

Language:

english

File:

PDF, 571 KB

english, 2011

11

Synthesis of (E)- and (Z)-29-Methylidyne-2,3-oxidosqualene Derivatives as Inhibitors of Liver and Yeast Oxidosqualene Cyclase.

Maurizio Ceruti, Franca Viola, Gianni Balliano, Paola Milla, Giorgio Roma, Giancarlo Grossi, Flavio Rocco

Journal:

Year:

2002

File:

PDF, 31 KB

2002

12

Umbelliferone Aminoalkyl Derivatives, a New Class of Squalene-Hopene Cyclase Inhibitors.

Giancarlo Cravotto, Gianni Balliano, Silvia Tagliapietra, Giovanni Palmisano, Andrea Penoni

Journal:

Year:

2005

File:

PDF, 24 KB

2005

13

Novel Squalene-Hopene Cyclase Inhibitors Derived from Hydroxycoumarins and Hydroxyacetophenones.

Giancarlo Cravotto, Gianni Balliano, Silvia Tagliapietra, Simonetta Oliaro-Bosso, Gian Mario Nano

Journal:

Year:

2005

File:

PDF, 16 KB

2005

14

ChemInform Abstract: Mechanism(s) of SWI/SNF-Induced Nucleosome Mobilization

Ning Liu, Angela Balliano, Jeffrey J. Hayes

Journal:

Year:

2011

File:

PDF, 18 KB

2011

15

Inhibitory Effect of Umbelliferone Aminoalkyl Derivatives on Oxidosqualene Cyclases from S. cerevisiae, T. cruzi, P. carinii, H. sapiens, and A. thaliana: a Structure–Activity Study

Simonetta Oliaro-Bosso, Franca Viola, Silvia Taramino, Silvia Tagliapietra, Alessandro Barge, Giancarlo Cravotto, Gianni Balliano

Journal:

Year:

2007

Language:

english

File:

PDF, 157 KB

english, 2007

16

Stigmasta-7,E-24(28)-dien-3β-ol from Bryonia dioica roots

L. Cattel, G. Balliano, O. Caputo

Journal:

Year:

1979

Language:

english

File:

PDF, 151 KB

english, 1979

17

Biosynthesis of stigmasta-7, E-24(28)-dien-3β-ol and 24α-alkyl sterols in Bryonia dioica

L. Cattel, G. Balliano, O. Caputo, L. Delprino

Journal:

Year:

1980

Language:

english

File:

PDF, 228 KB

english, 1980

18

Cyclization of squalene-2,3-epoxide to 10α-cucurbita-5,24-dien-3β-ol by microsomes from Cucurbita maxima seedlings

Gianni Balliano, Otto Caputo, Franca Viola, Laura Delprino, Luigi Cattel

Journal:

Year:

1983

Language:

english

File:

PDF, 773 KB

english, 1983

19

Synthesis and biological activity of azasqualenes, bis-azasqualenes and derivatives

Maurizio Ceruti, Gianni Balliano, Franca Viola, Luigi Cattel, Nicolas Gerst, Francis Schuber

Journal:

European Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 1.11 MB

english, 1987

20

Synthesis of a squalenoid oxaziridine and other new classes of squalene derivatives, as inhibitors of sterol biosynthesis

Maurizio Ceruti, Franca Viola, Gianni Balliano, Giorgio Grosa, Otto Caputo, Nicolas Gerst, Francis Schuber, Luigi Cattel

Journal:

European Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 633 KB

english, 1988

21

Synthesis and biological activity of 19-azasqualene 2,3-epoxide as inhibitor of 2,3-oxidosqualene cyclase

M Ceruti, F Rocco, F Viola, G Balliano, G Grosa, F Dosio, L Cattel

Journal:

European Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 869 KB

english, 1993

22

Design, synthesis, and biological evaluation of new (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol ethers as inhibitors of human and Trypanosoma cruzi oxidosqualene cyclase

Ubaldina Galli, Simonetta Oliaro-Bosso, Silvia Taramino, Serena Venegoni, Emanuele Pastore, Gian Cesare Tron, Gianni Balliano, Franca Viola, Giovanni Sorba

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 152 KB

english, 2007

23

Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: A model for the development of novel antiparasitic agents

Gianni Balliano, Henrietta Dehmlow, Simonetta Oliaro-Bosso, Matilde Scaldaferri, Silvia Taramino, Franca Viola, Giulia Caron, Johannes Aebi, Jean Ackermann

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 228 KB

english, 2009

24

Conversion of Squalene to the Pentacarbocyclic Hopene

Dirk J Reinert, Gianni Balliano, Georg E Schulz

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 337 KB

english, 2004

25

Umbelliferone aminoalkyl derivatives, a new class of squalene-hopene cyclase inhibitors

Giancarlo Cravotto, Gianni Balliano, Silvia Tagliapietra, Giovanni Palmisano, Andrea Penoni

Journal:

European Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 317 KB

english, 2004

26

Topology of DNA: When manipulation supports the lack of ‘space-filling’ imagination

Gianni Balliano, Paola Milla

Journal:

Biochemical Education

Year:

1997

Language:

english

File:

PDF, 234 KB

english, 1997

27

Stereospecific syntheses of trans-vinyldioxidosqualene and β-hydroxysulfide derivatives, as potent and time-dependent 2,3-oxidosqualene cyclase inhibitors

Franca Viola, Gianni Balliano, Paola Milla, Luigi Cattel, Flavio Rocco, Maurizio Ceruti

Journal:

Bioorganic & Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 285 KB

english, 2000

28

Thiol-modifying inhibitors for understanding squalene cyclase function

Paola Milla, Alexander Lenhart, Giorgio Grosa, Franca Viola, Wilhelm A. Weihofen, Georg E. Schulz, Gianni Balliano

Journal:

Year:

2002

Language:

english

File:

PDF, 313 KB

english, 2002

29

Serine proteinase inhibition by the active site titrant N α-(N,N-dimethylcarbamoyl)-α-azaornithine p-nitrophenyl ester : A comparative study

Paolo Ascenzi, Gianni Balliano, Carlo Gallina, Fabio Polticelli, Martino Bolognesi

Journal:

Year:

2000

Language:

english

File:

PDF, 857 KB

english, 2000

30

Über einen Fall von primärer Tuberkulose der Samenkanälchen des Hodens und des Nebenhodens

Arturo Balliano

Journal:

Year:

1912

Language:

german

File:

PDF, 1.73 MB

german, 1912

31

Subcellular localization of oxidosqualene cyclases fromArabidopsis thaliana, Trypanosoma cruzi, andPneumocystis cariniiexpressed in yeast

P. Milla, F. Viola, S. Oliaro Bosso, F. Rocco, L. Cattel, B. M. Joubert, R. J. LeClair, S. P. T. Matsuda, G. Balliano

Journal:

Year:

2002

Language:

english

File:

PDF, 407 KB

english, 2002

32

Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases fromSaccharomyces cerevisiae, Tripanosoma cruzi, andPneumocystis carinii

Simonetta Oliaro-Bosso, Franca Viola, Seiichi Matsuda, Giancarlo Cravotto, Silvia Tagliapietra, Gianni Balliano

Journal:

Year:

2004

Language:

english

File:

PDF, 401 KB

english, 2004

33

19-Azasqualene-2,3-epoxide and itsN-oxide: Metabolic fate and inhibitory effect on sterol biosynthesis inSaccharomyces cerevisiae

Paola Milla, Franca Viola, Maurizio Ceruti, Flavio Rocco, Luigi Cattel, Gianni Balliano

Journal:

Year:

1999

Language:

english

File:

PDF, 572 KB

english, 1999

34

The transformation of 10α-cucurbita-5,24-dien-3β-ol into cucurbitacin C by seedlings of Cucumis sativus

Gianni Balliano, Otto Caputo, Franca Viola, Laura DelPrino, Luigi Cattel

Journal:

Year:

1983

Language:

english

File:

PDF, 461 KB

english, 1983

35

Inhibition of bovine β-trypsin, human α-thrombin and porcine pancreatic β-kallikrein-B by 4′,6-diamidino-2-phenylindole, 6-amidinoindole and benzamidine: a comparative thermodynamic and X-ray structural study

Elena Casale, Charles Collyer, Paolo Ascenzi, Gianni Balliano, Paola Milla, Franca Viola, Mauro Fasano, Enea Menegatti, Martino Bolognesi

Journal:

Biophysical Chemistry

Year:

1995

Language:

english

File:

PDF, 615 KB

english, 1995

36

Farnesyloxycoumarins, a new class of squalene-hopene cyclase inhibitors

Giancarlo Cravotto, Gianni Balliano, Bruna Robaldo, Simonetta Oliaro-Bosso, Stefano Chimichi, Marco Boccalini

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 170 KB

english, 2004

37

Studies towards the identification of putative bioactive conformation of potent vasodilator arylidene N-acylhydrazone derivatives

Arthur E. Kümmerle, Juliana M. Raimundo, Carla M. Leal, Givanildo S. da Silva, Tatiane L. Balliano, Mariano A. Pereira, Carlos A. de Simone, Roberto T. Sudo, Gisele Zapata-Sudo, Carlos A.M. Fraga, Eli

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 380 KB

english, 2009

38

Novel ruthenium complexes as potential drugs for Chagas's disease: enzyme inhibition and in vitro/in vivo trypanocidal activity

Jean Jerley Nogueira Silva, Paulo Marcos Matta Guedes, Aderson Zottis, Tatiane Luciano Balliano, Francisco Ordelei Nascimento Silva, Luiz Gonzaga França Lopes, Javier Ellena, Glaucius Oliva, Adriano D

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 743 KB

english, 2010

39

Lipids, pasta and palazzi: The 8th Yeast Lipid Conference, Torino, Italy, 10–12 May, 2007

Gianni Balliano, Günther Daum

Journal:

FEMS Yeast Research

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

40

The squalene-2,3-epoxide cyclase as a model for the development of new drugs

L. Cattel, M. Ceruti, F. Viola, L. Delprino, G. Balliano, A. Duriatti, P. Bouvier-Navé

Journal:

Year:

1986

Language:

english

File:

PDF, 787 KB

english, 1986

41

Conversion of cyclolaudenol to 24α- and 24β-ethylsterols in the cucurbitaceae

Gianni Balliano, Otto Caputo, Franca Viola, Laura Delprino, Luigi Cattel

Journal:

Year:

1983

Language:

english

File:

PDF, 250 KB

english, 1983

42

3-carboxy-4-nitrophenyl-dithio-1,1′,2-trisnorsqualene: A site-directed inactivator of yeast oxidosqualene cyclase

Gianni Balliano, Giorgio Grosa, Paola Milla, Franca Viola, Luigi Cattel

Journal:

Year:

1993

Language:

english

File:

PDF, 405 KB

english, 1993

43

2,3-oxidosqualene cyclase: From azasqualenes to new site-directed inhibitors

Luigi Cattel, Maurizio Ceruti, Gianni Balliano, Franca Viola, Giorgio Grosa, Flavio Rocco, Paola Brusa

Journal:

Year:

1995

Language:

english

File:

PDF, 1.09 MB

english, 1995

44

Inhibition of Bovine β-Trypsin by the Active-Site Titrant Nα-(N,N-Dimethylcarbamoyl)-α-Azaornithine p-Nitrophenyl Ester: A Kinetic and X-Ray Crystallographic Study

P. Ascenzi, G. Balliano, P. Milla, R. Ferraccioli, P. Sartori, K. Djinoviccarugo, M. Bolognesi

Journal:

Biochemical and Biophysical Research Communications

Year:

1995

File:

PDF, 352 KB

1995

45

N-Ethoxycarbonyl-D-phenylalanyl-L-prolyl-α-azalysinep-Nitrophenyl Ester: A Novel, High Selective and Optimal Chromogenic Active Site Titrant for Human and Bovine α-, β- and γ-Thrombin

Gianni Balliano, Paola Milla, Cesare Giordano, Carlo Gallina, Massimo Coletta, Enea Menegatti, Menico Rizzi, Martino Bolognesi, Paolo Ascenzi

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 113 KB

english, 1996

46

Human α-Thrombin Inhibition by the Active Site Titrant Nα-(N,N-dimethylcarbamoyl)-α-azalysine p-nitrophenyl ester: A Comparative Kinetic and X-ray Crystallographic Study

Marco Nardini, Alessandra Pesce, Menico Rizzi, Elena Casale, Raffaella Ferraccioli, Gianni Balliano, Paola Milla, Paolo Ascenzi, Martino Bolognesi

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 677 KB

english, 1996

47

Human α-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-d-phe-pro-α-azalys p-nitrophenyl ester and N-carbobenzoxy-pro-α-azalys p-nitrophenyl ester: A kinetic, thermodynamic and x-ray crystallographic study

Giuseppina De Simone, Gianni Balliano, Paola Milla, Carlo Gallina, Cesare Giordano, Cataldo Tarricone, Menico Rizzi, Martino Bolognesi, Paolo Ascenzi

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 362 KB

english, 1997

48

Characterization and partial purification of squalene-2,3-oxide cyclase from Saccharomyces cerevisiae

Gianni Balliano, Franca Viola, Maurizio Ceruti, Luigi Cattel

Journal:

Archives of Biochemistry and Biophysics

Year:

1992

Language:

english

File:

PDF, 868 KB

english, 1992

49

Inhibition of sterol biosynthesis in Saccharomyces cerevisiae by N,N-diethylazasqualene and derivatives

Gianni Balliano, Franca Viola, Maurizio Ceruti, Luigi Cattel

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1988

Language:

english

File:

PDF, 1007 KB

english, 1988

50

In vitro inhibition of animal and higher plants 2,3-oxidosqualene-sterol cyclases by 2-aza-2,3- dihydrosqualene and derivatives, and by other ammonium-containing molecules

Albert Duriatti, Pierrette Bouvier-Nave, Pierre Benveniste, Francis Schuber, Laura Delprino, Gianni Balliano, Luigi Cattel

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 1.21 MB

english, 1985

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