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1

EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib

Kobayashi, Susumu, Boggon, Titus J., Dayaram, Tajhal, Jänne, Pasi A., Kocher, Olivier, Meyerson, Matthew, Johnson, Bruce E., Eck, Michael J., Tenen, Daniel G., Halmos, Balázs

Journal:

Boston Medical and Surgical Journal

Year:

2005

Language:

english

File:

PDF, 256 KB

english, 2005

2

Tyrosine Phosphorylation of Mitochondrial Pyruvate Dehydrogenase Kinase 1 Is Important for Cancer Metabolism

Taro Hitosugi, Jun Fan, Tae-Wook Chung, Katherine Lythgoe, Xu Wang, Jianxin Xie, Qingyuan Ge, Ting-Lei Gu, Roberto D. Polakiewicz, Johannes L. Roesel, Georgia Z. Chen, Titus J. Boggon, Sagar Lonial, H

Journal:

Year:

2011

Language:

english

File:

PDF, 1.99 MB

english, 2011

3

The Thalamic Connections of the Parietal and Frontal Lobes of the Brain in the Monkey

Clark, W. E. L. G., Boggon, R. H.

Journal:

Philosophical Transactions Biological Sciences

Year:

1935

File:

PDF, 11.23 MB

1935

4

Implication of Tubby Proteins as Transcription Factors by Structure-Based Functional Analysis

Journal:

Year:

1999

Language:

english

File:

PDF, 1.05 MB

english, 1999

5

The Thalamic Connections of the Parietal and Frontal Lobes of the Brain in the Monkey

W. E. Le Gros Clark and R. H. Boggon

Journal:

Philosophical Transactions of the Royal Society of London Series B Biological Sciences (1934-1990)

Year:

1935

Language:

english

File:

PDF, 8.82 MB

english, 1935

6

Structure and Clinical Relevance of the Epidermal Growth Factor Receptor in Human Cancer

Kumar, A., Petri, E. T., Halmos, B., Boggon, T. J.

Journal:

Journal of Clinical Oncology

Year:

2008

Language:

english

File:

PDF, 642 KB

english, 2008

7

Structure and vascular function of MEKK3–cerebral cavernous malformations 2 complex

Fisher, Oriana S., Deng, Hanqiang, Liu, Dou, Zhang, Ya, Wei, Rong, Deng, Yong, Zhang, Fan, Louvi, Angeliki, Turk, Benjamin E., Boggon, Titus J., Su, Bing

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 2.28 MB

english, 2015

8

Polyorchidism

R. Hodgson Boggon

Journal:

British Journal of Surgery

Year:

1933

Language:

english

File:

PDF, 691 KB

english, 1933

9

Carcinoma of the male urethra

R. Hodgson Boggon

Journal:

British Journal of Surgery

Year:

1933

Language:

english

File:

PDF, 357 KB

english, 1933

10

Structure and regulation of Src family kinases

Boggon, Titus J, Eck, Michael J

Journal:

Year:

2004

Language:

english

File:

PDF, 348 KB

english, 2004

11

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

Ross L. Levine, Martha Wadleigh, Jan Cools, Benjamin L. Ebert, Gerlinde Wernig, Brian J.P. Huntly, Titus J. Boggon, Iwona Wlodarska, Jennifer J. Clark, Sandra Moore, Jennifer Adelsperger, Sumin Koo, J

Journal:

Year:

2005

Language:

english

File:

PDF, 459 KB

english, 2005

12

Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

Cai-Hong Yun, Titus J. Boggon, Yiqun Li, Michele S. Woo, Heidi Greulich, Matthew Meyerson, Michael J. Eck

Journal:

Year:

2007

Language:

english

File:

PDF, 944 KB

english, 2007

13

Identification of Driver and Passenger Mutations of FLT3 by High-Throughput DNA Sequence Analysis and Functional Assessment of Candidate Alleles

Stefan Fröhling, Claudia Scholl, Ross L. Levine, Marc Loriaux, Titus J. Boggon, Olivier A. Bernard, Roland Berger, Hartmut Döhner, Konstanze Döhner, Benjamin L. Ebert, Sewit Teckie, Todd R. Golub, Jin

Journal:

Year:

2007

Language:

english

File:

PDF, 1.07 MB

english, 2007

14

Screening for phasing atoms in protein crystallography

Titus J Boggon, Lawrence Shapiro

Journal:

Year:

2000

Language:

english

File:

PDF, 492 KB

english, 2000

15

JAK3: A two-faced player in hematological disorders

Melanie G. Cornejo, Titus J. Boggon, Thomas Mercher

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2009

Language:

english

File:

PDF, 438 KB

english, 2009

16

Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase

Brian P. Chiswell, Amy L. Stiegler, Ziba Razinia, Elina Nalibotski, Titus J. Boggon, David A. Calderwood

Journal:

Journal of Structural Biology

Year:

2010

Language:

english

File:

PDF, 2.11 MB

english, 2010

17

Calcium Induced Conformational Changes In The Cytoplasmic Tail Of Polycystin-2

Petri, Edward T., Celic, Andjelka S., Boggon, Titus J., Ehrlich, Barbara E.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 45 KB

english, 2009

18

PCV23 Clopidodgrel and Statin Prescribing Patterns in ACS Patients – an Observational Study Using Linked Secondary and Primary Care Data in a UK Population 2003-2009

R. Boggon, K.A. Fox, A. Begg, K. Ray, A. Timmis, H. Hemingway, C.E. Emmas, T. Van staa

Journal:

Value in Health

Year:

2011

Language:

english

File:

PDF, 60 KB

english, 2011

19

PCV100 Resource Use in Patients with Acute Coronary Syndrome - an Observational Study Across Secondary and Primary Care in a UK Population

R. Boggon, K.A. Fox, A. Begg, K. Ray, A. Timmis, H. Hemingway, C.E. Emmas, T. Van staa

Journal:

Value in Health

Year:

2011

Language:

english

File:

PDF, 60 KB

english, 2011

20

Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth

Hitosugi, T., Kang, S., Vander Heiden, M. G., Chung, T.-W., Elf, S., Lythgoe, K., Dong, S., Lonial, S., Wang, X., Chen, G. Z., Xie, J., Gu, T.-L., Polakiewicz, R. D., Roesel, J. L., Boggon, T. J., Khu

Journal:

Science Signaling

Year:

2009

Language:

english

File:

PDF, 904 KB

english, 2009

21

Mechanism for KRIT1 Release of ICAP1-Mediated Suppression of Integrin Activation

Liu, Weizhi, Draheim, Kyle M., Zhang, Rong, Calderwood, David A., Boggon, Titus J.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.72 MB

english, 2013

22

Variability of antibiotic prescribing in patients with chronic obstructive pulmonary disease exacerbations: a cohort study

Rachael Boggon, Richard Hubbard, Liam Smeeth, Martin Gulliford…

Journal:

BMC Pulmonary Medicine

Year:

2013

Language:

english

File:

PDF, 183 KB

english, 2013

23

Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal region

Reshetnyak, A. V., Nelson, B., Shi, X., Boggon, T. J., Pavlenco, A., Mandel-Bausch, E. M., Tome, F., Suzuki, Y., Sidhu, S. S., Lax, I., Schlessinger, J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 1.15 MB

english, 2013

24

A Network of Interactions Enables CCM3 and STK24 to Coordinate UNC13D-Driven Vesicle Exocytosis in Neutrophils

Zhang, Yong, Tang, Wenwen, Zhang, Haifeng, Niu, Xiaofeng, Xu, Yingke, Zhang, Jiasheng, Gao, Kun, Pan, Weijun, Boggon, Titus J., Toomre, Derek, Min, Wang, Wu, Dianqing

Journal:

Developmental Cell

Year:

2013

Language:

english

File:

PDF, 2.36 MB

english, 2013

25

Signaling pathways and the cerebral cavernous malformations proteins: lessons from structural biology

Fisher, Oriana S., Boggon, Titus J.

Journal:

Cellular and Molecular Life Sciences

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

26

Structural studies of cerebral cavernous malformations 2 (CCM2) reveal a folded helical domain at its C-terminus

Fisher, Oriana S., Zhang, Rong, Li, Xiaofeng, Murphy, James W., Demeler, Borries, Boggon, Titus J.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.38 MB

english, 2013

27

Polycystin-2 Contains an Unpaired EF-hand Motif which May Serve as a Ca2+-Sensitive Regulator of Polycystin-2 Channel Activity

Celic, Andjelka, Petri, Edward T., Hodsdon, Michael E., Boggon, Titus J., Ehrlich, Barbara E.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 54 KB

english, 2010

28

Pseudosubstrate Regulation of the Type II P21-Activated Kinases (PAKs)

Boggon, Titus J.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 53 KB

english, 2013

29

PROGNOSIS

Wallace, CuthbertS., Maybury, B.C., Robinson, R.H.O.B., Williams, B.W., Boggon, R.H.

Journal:

Year:

1935

Language:

english

File:

PDF, 221 KB

english, 1935

30

Mineralocorticoid Receptor Phosphorylation Regulates Ligand Binding and Renal Response to Volume Depletion and Hyperkalemia

Shibata, Shigeru, Rinehart, Jesse, Zhang, Junhui, Moeckel, Gilbert, Castañeda-Bueno, María, Stiegler, Amy L., Boggon, Titus J., Gamba, Gerardo, Lifton, Richard P.

Journal:

Cell Metabolism

Year:

2013

Language:

english

File:

PDF, 2.43 MB

english, 2013

31

FOUR CASES OF ANTHRAX TREATED WITH SCLAVO'S SERUM

Journal:

Year:

1927

Language:

english

File:

PDF, 476 KB

english, 1927

32

Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity

Chen, Catherine, Ha, Byung Hak, Thévenin, Anastasia F., Lou, Hua Jane, Zhang, Rong, Yip, Kevin Y., Peterson, Jeffrey R., Gerstein, Mark, Kim, Philip M., Filippakopoulos, Panagis, Knapp, Stefan, Boggon

Journal:

Year:

2014

Language:

english

File:

PDF, 783 KB

english, 2014

33

THE MECHANICS OF APPENDICITIS

Williams, B.W., Boggon, R.H.

Journal:

Year:

1934

Language:

english

File:

PDF, 364 KB

english, 1934

34

Structure-guided studies of the SHP-1/JAK1 interaction provide new insights into phosphatase catalytic domain substrate recognition

Alicea-Velázquez, Nilda L., Jakoncic, Jean, Boggon, Titus J.

Journal:

Journal of Structural Biology

Year:

2013

Language:

english

File:

PDF, 1.66 MB

english, 2013

35

RUPTURE OF OVARIAN BLOOD-CYSTS SIMULATING ACUTE APPENDICITIS

Hodgson Boggon, R., Wrigley, A.J.

Journal:

Year:

1931

Language:

english

File:

PDF, 561 KB

english, 1931

36

THE BARIUM ENEMA IN THE DIAGNOSIS OF INTUSSUSCEPTION

Hodgson Boggon, R.

Journal:

Year:

1932

Language:

english

File:

PDF, 615 KB

english, 1932

37

POST PARTUM AVULSION OF THE UTERUS: A CASE OF RECOVERY

Journal:

Year:

1927

Language:

english

File:

PDF, 404 KB

english, 1927

38

Marangoni and Interfacial Phenomena in Materials Processing || Protein Crystal Movements and Fluid Flows during Microgravity Growth

Titus J. Boggon, Naomi E. Chayen, Edward H. Snell, Jun Dong, Peter Lautenschlager, Lothar Potthast, D. Peter Siddons, Vivian Stojanoff, Elspeth Gordon, Andrew W. Thompson, Peter F. Zagalsky, Ru-Chang

Journal:

Philosophical Transactions Mathematical Physical & Engineering Sciences

Year:

1998

Language:

english

File:

PDF, 2.97 MB

english, 1998

39

Global Analysis of Human Nonreceptor Tyrosine Kinase Specificity Using High-Density Peptide Microarrays

Deng, Yang, Alicea-Velázquez, Nilda L., Bannwarth, Ludovic, Lehtonen, Soili I., Boggon, Titus J., Cheng, Heung-Chin, Hytönen, Vesa P., Turk, Benjamin E.

Journal:

Journal of Proteome Research

Year:

2014

Language:

english

File:

PDF, 981 KB

english, 2014

40

Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation

Huet-Calderwood, C., Brahme, N. N., Kumar, N., Stiegler, A. L., Raghavan, S., Boggon, T. J., Calderwood, D. A.

Journal:

Journal of Cell Science

Year:

2014

Language:

english

File:

PDF, 3.29 MB

english, 2014

41

[IEEE 2014 IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) - Valencia, Spain (2014.6.1-2014.6.4)] IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) - Data quality in European primary care research databases. Report of a workshop held in London September 2013

Tate, A. Rosemary, Kalra, Dipak, Boggon, Rachael, Beloff, Natalia, Puri, Shivani, Williams, Tim

Year:

2014

Language:

english

File:

PDF, 336 KB

english, 2014

42

C-Cadherin Ectodomain Structure and Implications for Cell Adhesion Mechanisms

Journal:

Year:

2002

Language:

english

File:

PDF, 813 KB

english, 2002

43

Resource Utilization and Outcomes in Patients with Atrial Fibrillation

Rachael Boggon,Gregory Y. H. Lip…

Journal:

Applied Health Economics and Health Policy

Year:

2012

Language:

english

File:

PDF, 148 KB

english, 2012

44

Cancer recording and mortality in the General Practice Research Database and linked cancer registries

Boggon, Rachael, van Staa, Tjeerd P., Chapman, Michael, Gallagher, Arlene M., Hammad, Tarek A., Richards, Mike A.

Journal:

Pharmacoepidemiology and Drug Safety

Year:

2013

Language:

english

File:

PDF, 96 KB

english, 2013

45

Two Amino Acid Residues Confer Different Binding Affinities of Abelson Family Kinase Src Homology 2 Domains for Phosphorylated Cortactin

Gifford, Stacey M., Liu, Weizhi, Mader, Christopher C., Halo, Tiffany L., Machida, Kazuya, Boggon, Titus J., Koleske, Anthony J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.80 MB

english, 2014

46

Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors

Choi, Jaehyuk, Landrette, Sean F., Wang, Tiffany, Evans, Perry, Bacchiocchi, Antonella, Bjornson, Robert, Cheng, Elaine, Stiegler, Amy L., Gathiaka, Symon, Acevedo, Orlando, Boggon, Titus J., Krautham

Journal:

Pigment Cell & Melanoma Research

Year:

2014

Language:

english

File:

PDF, 7.42 MB

english, 2014

47

MERTK controls melanoma cell migration and survival and differentially regulates cell behavior relative to AXL

Tworkoski, Kathryn A., Platt, James T., Bacchiocchi, Antonella, Bosenberg, Marcus, Boggon, Titus J., Stern, David F.

Journal:

Pigment Cell & Melanoma Research

Year:

2013

Language:

english

File:

PDF, 7.88 MB

english, 2013

48

[IEEE 2014 IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) - Valencia, Spain (2014.6.1-2014.6.4)] IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) - A pragmatic approach for measuring data quality in primary care databases

Dungey, Sheena, Beloff, Natalia, Puri, Shivani, Boggon, Rachael, Williams, Tim, Tate, A. Rosemary

Year:

2014

Language:

english

File:

PDF, 916 KB

english, 2014

49

The Strength and Cooperativity of KIT Ectodomain Contacts Determine Normal Ligand-Dependent Stimulation or Oncogenic Activation in Cancer

Reshetnyak, Andrey V., Opatowsky, Yarden, Boggon, Titus J., Folta-Stogniew, Ewa, Tome, Francisco, Lax, Irit, Schlessinger, Joseph

Journal:

Year:

2015

Language:

english

File:

PDF, 2.56 MB

english, 2015

50

Glutamate Dehydrogenase 1 Signals through Antioxidant Glutathione Peroxidase 1 to Regulate Redox Homeostasis and Tumor Growth

Jin, Lingtao, Li, Dan, Alesi, Gina N., Fan, Jun, Kang, Hee-Bum, Lu, Zhou, Boggon, Titus J., Jin, Peng, Yi, Hong, Wright, Elizabeth R., Duong, Duc, Seyfried, Nicholas T., Egnatchik, Robert, DeBerardini

Journal:

Year:

2015

Language:

english

File:

PDF, 4.80 MB

english, 2015

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