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1

Evidence-based clinical practice update: practice guidelines for anterior cruciate ligament rehabilitation based on a systematic review and multidisciplinary consensus

van Melick, Nicky, van Cingel, Robert E H, Brooijmans, Frans, Neeter, Camille, van Tienen, Tony, Hullegie, Wim, Nijhuis-van der Sanden, Maria W G

Journal:

British Journal of Sports Medicine

Year:

2016

Language:

english

File:

PDF, 564 KB

english, 2016

2

Late Proterozoic extensional collapse in the Arabian-Nubian Shield

BLASBAND, B., WHITE, S., BROOIJMANS, P., DE BOORDER, H., VISSER, W.

Journal:

Journal of the Geological Society

Year:

2000

Language:

english

File:

PDF, 621 KB

english, 2000

3

A radiation-hard dual channel 4-bit pipeline for a 12-bit 40 MS/s ADC prototype with extended dynamic range for the ATLAS Liquid Argon Calorimeter readout electronics upgrade at the CERN LHC

Kuppambatti, J, Ban, J, Andeen, T, Kinget, P, Brooijmans, G

Journal:

Journal of Instrumentation

Year:

2013

Language:

english

File:

PDF, 1.58 MB

english, 2013

4

4-Substituted-7-azaindoles bearing a ureidobenzofuranone moiety as potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR)

Hwei-Ru Tsou, Gloria MacEwan, Gary Birnberg, Nan Zhang, Natasja Brooijmans, Lourdes Toral-Barza, Irwin Hollander, Semiramis Ayral-Kaloustian, Ker Yu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.71 MB

english, 2010

5

Discovery of 3,6-dihydro-2H-pyran as a morpholine replacement in 6-aryl-1H-pyrazolo[3,4-d]pyrimidines and 2-arylthieno[3,2-d]pyrimidines: ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR)

Joshua Kaplan, Jeroen C. Verheijen, Natasja Brooijmans, Lourdes Toral-Barza, Irwin Hollander, Ker Yu, Arie Zask

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 675 KB

english, 2010

6

Discovery and optimization of 2-(4-substituted-pyrrolo[2,3-b]pyridin-3-yl)methylene-4-hydroxybenzofuran-3(2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR)

Hwei-Ru Tsou, Gloria MacEwan, Gary Birnberg, George Grosu, Matthew G. Bursavich, Joel Bard, Natasja Brooijmans, Lourdes Toral-Barza, Irwin Hollander, Tarek S. Mansour, Semiramis Ayral-Kaloustian, Ker

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.24 MB

english, 2010

7

Synthesis and SAR of Novel 4-Morpholinopyrrolopyrimidine Derivatives as Potent Phosphatidylinositol 3-Kinase Inhibitors

Chen, Zecheng, Venkatesan, Aranapakam M., Dehnhardt, Christoph M., Ayral-Kaloustian, Semiramis, Brooijmans, Natasja, Mallon, Robert, Feldberg, Larry, Hollander, Irwin, Lucas, Judy, Yu, Ker, Kong, Fang

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.14 MB

english, 2010

8

[IEEE 2008 IEEE Nuclear Science Symposium and Medical Imaging conference (2008 NSS/MIC) - Dresden, Germany (2008.10.19-2008.10.25)] 2008 IEEE Nuclear Science Symposium Conference Record - Performance of the SiGe HBT 8HP and 8WL technologies after high dose/fluence radiation exposure

Rice, J. S., Ullan, M., Brooijmans, G., Cressler, J. D., Damiani, D., Diez, S., Gadfort, T., Grillo, A. A., Hackenburg, R., Hare, G., Jones, A., Kierstead, J., Kononenko, W., Mandic, I., Martinez-McKi

Year:

2008

Language:

english

File:

PDF, 3.21 MB

english, 2008

9

Network Structure in Acrylate Systems: Effect of Junction Topology on Cross-Link Density and Macroscopic Gel Properties

Wu, Bing, Chassé, Walter, Peters, Ron, Brooijmans, Ton, Dias, Aylvin A., Heise, Andreas, Duxbury, Christopher J., Kentgens, Arno P. M., Brougham, Dermot F., Litvinov, Victor M.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.92 MB

english, 2016

10

Development of ATLAS Liquid Argon Calorimeter readout electronics for the HL-LHC

Journal:

Journal of Instrumentation

Year:

2017

File:

PDF, 816 KB

2017

11

ChemInform Abstract: Kinase Domain Mutations in Cancer: Implications for Small Molecule Drug Design Strategies

Jack A. Bikker, Natasja Brooijmans, Allan Wissner, Tarek S. Mansour

Journal:

Year:

2009

File:

PDF, 15 KB

2009

12

Novel purine and pyrazolo[3,4-d]pyrimidine inhibitors of PI3 kinase-α: Hit to lead studies

Adam M. Gilbert, Pawel Nowak, Natasja Brooijmans, Matthew G. Bursavich, Christoph Dehnhardt, Efren Delos Santos, Larry R. Feldberg, Irwin Hollander, Stephen Kim, Sabrina Lombardi, Kaapjoo Park, Aranap

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 327 KB

english, 2010

13

Evaluation of silicon-germanium (SiGe) bipolar technologies for use in an upgraded atlas detector

M. Ullán, J. Rice, G. Brooijmans, J.D. Cressler, D. Damiani, S. Díez, T. Gadfort, A.A. Grillo, R. Hackenburg, G. Hare, A. Jones, J. Kierstead, W. Kononenko, I. Mandić, F. Martinez-McKinney, J. Metcalf

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

2009

Language:

english

File:

PDF, 721 KB

english, 2009

14

5-Vinyl-3-pyridinecarbonitrile inhibitors of PKCθ: Optimization of enzymatic and functional activity

L. Nathan Tumey, Niala Bhagirath, Agnes Brennan, Natasja Brooijmans, Julie Lee, Xiaoke Yang, Diane H. Boschelli

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.41 MB

english, 2009

15

Novel benzofuran-3-one indole inhibitors of PI3 kinase-α and the mammalian target of rapamycin: Hit to lead studies

Matthew G. Bursavich, Natasja Brooijmans, Lawrence Feldberg, Irwin Hollander, Stephen Kim, Sabrina Lombardi, Kaapjoo Park, Robert Mallon, Adam M. Gilbert

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 513 KB

english, 2010

16

5-Ureidobenzofuranone indoles as potent and efficacious inhibitors of PI3 kinase-α and mTOR for the treatment of breast cancer

Nan Zhang, Semiramis Ayral-Kaloustian, James T. Anderson, Thai Nguyen, Sasmita Das, Aranapakam M. Venkatesan, Natasja Brooijmans, Judy Lucas, Ker Yu, Irwin Hollander, Robert Mallon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 467 KB

english, 2010

17

Determination of scanning efficiencies in experiments using nuclear emulsion sheets

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

2000

Language:

english

File:

PDF, 67 KB

english, 2000

18

The CHORUS scintillating fiber tracker and opto-electronic readout system

P. Annis, S. Aoki, G. Brooijmans, J. Brunner, J. Dupraz, J. Dupont, J.-P. Fabre, D. Favart, W. Flegel, D. Frekers, G. Grégoire, M. Gruwé, J. Herin, K. Hoepfner, M. Kobayashi, J. Konijn, T. Kozaki, P.

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

1998

Language:

english

File:

PDF, 635 KB

english, 1998

19

K/π production ratios from 450 GeV/c protons on beryllium

G Ambrosini, R Arsenescu, K Bernier, C Biino, M Bonesini, W Bonivento, K Borer, G Brooijmans, M.G Catanesi, G Collazuol, D Daniels, F Dittus, K Elsener, A Godley, A Grant, G Gregoire, A Guglielmi, S K

Journal:

Physics Letters B

Year:

1998

Language:

english

File:

PDF, 173 KB

english, 1998

20

Observation of neutrino induced diffractive Ds∗+ production and subsequent decay Ds∗+→Ds+→τ+→μ+

P. Annis, S. Aoki, A. Artamonov, E. Barbuto, A. di Bartolomeo, D. Bonekämper, C. Bozza, G. Brooijmans, J. Brunner, A. Bülte, S. Buontempo, A. Capone, F. Cassol, M.G. Catanesi, M. Chikawa, A. Cocco, D.

Journal:

Physics Letters B

Year:

1998

Language:

english

File:

PDF, 187 KB

english, 1998

21

An enriched structural kinase database to enable kinome-wide structure-based analyses and drug discovery

Natasja Brooijmans, Yu-Wei Chang, Dominick Mobilio, Rajiah A. Denny, Christine Humblet

Journal:

Protein Science

Year:

2010

Language:

english

File:

PDF, 849 KB

english, 2010

22

A lead discovery strategy driven by a comprehensive analysis of proteases in the peptide substrate space

Sai Chetan K. Sukuru, Florian Nigsch, Jean Quancard, Martin Renatus, Rajiv Chopra, Natasja Brooijmans, Dmitri Mikhailov, Zhan Deng, Allen Cornett, Jeremy L. Jenkins, Ulrich Hommel, John W. Davies, Mei

Journal:

Protein Science

Year:

2010

Language:

english

File:

PDF, 1.19 MB

english, 2010

23

Stability of macromolecular complexes

Natasja Brooijmans, Kim A. Sharp, Irwin D. Kuntz

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2002

Language:

english

File:

PDF, 225 KB

english, 2002

24

Development and validation of a modular, extensible docking program: DOCK 5

Demetri T. Moustakas, P. Therese Lang, Scott Pegg, Eric Pettersen, Irwin D. Kuntz, Natasja Brooijmans, Robert C. Rizzo

Journal:

Journal of Computer-Aided Molecular Design

Year:

2006

Language:

english

File:

PDF, 877 KB

english, 2006

25

Chemical space sampling by different scoring functions and crystal structures

Natasja Brooijmans, Christine Humblet

Journal:

Journal of Computer-Aided Molecular Design

Year:

2010

Language:

english

File:

PDF, 658 KB

english, 2010

26

Performance and calibration of the CHORUS scintillating fiber tracker and opto-electronics readout system

P. Annis, S. Aoki, G. Brooijmans, J. Brunner, M. de Jong, J.-P. Fabre, R. Ferreira, W. Flegel, D. Frekers, G. Gregoire, M. Gruwé, J. Herin, K. Hoepfner, M. Kobayashi, J. Konijn, V. Lemaitre, P. Lender

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

1995

Language:

english

File:

PDF, 413 KB

english, 1995

27

Pion yield from 450 GeV/c protons on beryllium

G. Ambrosini, R. Arsenescu, K. Bernier, C. Biino, M. Bonesini, W. Bonivento, K. Borer, G. Brooijmans, M.G. Catanesi, G. Collazuol, D. Daniels, F. Dittus, K. Elsener, A. Godley, A. Grant, G. Gregoire,

Journal:

Physics Letters B

Year:

1998

Language:

english

File:

PDF, 167 KB

english, 1998

28

A Protein Relational Database and Protein Family Knowledge Bases to Facilitate Structure-Based Design Analyses

Dominick Mobilio, Gary Walker, Natasja Brooijmans, Ramaswamy Nilakantan, R. Aldrin Denny, Jason DeJoannis, Eric Feyfant, Rupesh K. Kowticwar, Jyoti Mankala, Satish Palli, Sairam Punyamantula, Maneesh

Journal:

Chemical Biology & Drug Design

Year:

2010

Language:

english

File:

PDF, 658 KB

english, 2010

29

Chemical Space Sampling in Virtual Screening by Different Crystal Structures

Natasja Brooijmans, Christine Humblet

Journal:

Chemical Biology & Drug Design

Year:

2010

Language:

english

File:

PDF, 197 KB

english, 2010

30

A Pan-African core complex in the Sinai, Egypt

B. Blasband, P. Brooijmans, P. Dirks, W. Visser, S. White

Journal:

Netherlands Journal of Geosciences – Geologie en Mijnbouw

Year:

1997

Language:

english

File:

PDF, 530 KB

english, 1997

31

Boosted objects: a probe of beyond the standard model physics

A. Abdesselam, A. Belyaev, E. Bergeaas Kuutmann, U. Bitenc, G. Brooijmans, J. Butterworth, P. Bruckman de Renstrom, D. Buarque Franzosi, R. Buckingham, B. Chapleau, M. Dasgupta, A. Davison, J. Dolen,

Journal:

The European Physical Journal C

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

32

Morpholine Derivatives Greatly Enhance the Selectivity of Mammalian Target of Rapamycin (mTOR) Inhibitors

Kaplan, Joshua, Verheijen, Jeroen C., Richard, David J., Curran, Kevin, Zask, Arie, Brooijmans, Natasja, Bennett, Eric M., Toral-Barza, Lourdes, Hollander, Irwin, Ayral-Kaloustian, Semiramis

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 2.13 MB

english, 2009

33

Kinase Domain Mutations in Cancer: Implications for Small Molecule Drug Design Strategies

Bikker, Jack A., Brooijmans, Natasja, Wissner, Allan, Mansour, Tarek S.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 2.12 MB

english, 2009

34

Identification of 2-oxatriazines as highly potent pan-PI3K/mTOR dual inhibitors

Christoph M. Dehnhardt, Aranapakam M. Venkatesan, Zecheng Chen, Efren Delos-Santos, Semiramis Ayral-Kaloustian, Natasja Brooijmans, Ker Yu, Irwin Hollander, Larry Feldberg, Judy Lucas, Robert Mallon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 561 KB

english, 2011

35

A structural informatics approach to mine kinase knowledge bases

Natasja Brooijmans, Dominick Mobilio, Gary Walker, Ramaswamy Nilakantan, Rajiah A. Denny, Eric Feyfant, David Diller, Jack Bikker, Christine Humblet

Journal:

Drug Discovery Today

Year:

2010

Language:

english

File:

PDF, 810 KB

english, 2010

36

Hydrocarbon-degrading bacteria: the oil-spill clean-up crew

Rob J. W. Brooijmans, Margreet I. Pastink, Roland J. Siezen

Journal:

Microbial Biotechnology

Year:

2009

Language:

english

File:

PDF, 692 KB

english, 2009

37

Genomics of microalgae, fuel for the future?

Rob J. W. Brooijmans, Roland J. Siezen

Journal:

Microbial Biotechnology

Year:

2010

Language:

english

File:

PDF, 1.04 MB

english, 2010

38

Geothermobarometric evidence for a metamorphic core complex in Sinai, Egypt

P Brooijmans, B Blasband, S.H White, W.J Visser, P Dirks

Journal:

Precambrian Research

Year:

2003

Language:

english

File:

PDF, 847 KB

english, 2003

39

Bis(morpholino-1,3,5-triazine) Derivatives: Potent Adenosine 5′-Triphosphate Competitive Phosphatidylinositol-3-kinase/Mammalian Target of Rapamycin Inhibitors: Discovery of Compound 26 (PKI-587), a Highly Efficacious Dual Inhibitor

Venkatesan, Aranapakam M., Dehnhardt, Christoph M., Delos Santos, Efren, Chen, Zecheng, Dos Santos, Osvaldo, Ayral-Kaloustian, Semiramis, Khafizova, Gulnaz, Brooijmans, Natasja, Mallon, Robert, Hollan

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 980 KB

english, 2010

40

Discovery of 4-Morpholino-6-aryl-1 H -pyrazolo[3,4- d ]pyrimidines as Highly Potent and Selective ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin (mTOR): Optimization of the 6-Aryl Substituent

Verheijen, Jeroen C., Richard, David J., Curran, Kevin, Kaplan, Joshua, Lefever, Mark, Nowak, Pawel, Malwitz, David J., Brooijmans, Natasja, Toral-Barza, Lourdes, Zhang, Wei-Guo, Lucas, Judy, Hollande

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 161 KB

english, 2009

41

Biased retrieval of chemical series in receptor-based virtual screening

Natasja Brooijmans, Jason B. Cross, Christine Humblet

Journal:

Journal of Computer-Aided Molecular Design

Year:

2010

Language:

english

File:

PDF, 344 KB

english, 2010

42

Heme and menaquinone induced electron transport in lactic acid bacteria

Rob Brooijmans, Bart Smit, Filipe Santos, Jan van Riel, Willem M de Vos, Jeroen Hugenholtz

Journal:

Microbial Cell Factories

Year:

2009

Language:

english

File:

PDF, 1.61 MB

english, 2009

43

Jet substructure at the Tevatron and LHC: new results, new tools, new benchmarks

Altheimer, A, Arora, S, Asquith, L, Brooijmans, G, Butterworth, J, Campanelli, M, Chapleau, B, Cholakian, A E, Chou, J P, Dasgupta, M, Davison, A, Dolen, J, Ellis, S D, Essig, R, Fan, J J, Field, R, F

Journal:

Journal of Physics G Nuclear and Particle Physics

Year:

2012

Language:

english

File:

PDF, 2.29 MB

english, 2012

44

Molecular Recognition and Docking Algorithms

Brooijmans, Natasja, Kuntz, Irwin D.

Journal:

Annual Review of Biophysics and Biomolecular Structure

Year:

2003

Language:

english

File:

PDF, 278 KB

english, 2003

45

Lead Optimization of N-3-Substituted 7-Morpholinotriazolopyrimidines as Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitors: Discovery of PKI-402

Dehnhardt, Christoph M., Venkatesan, Aranapakam M., Delos Santos, Efren, Chen, Zecheng, Santos, Osvaldo, Ayral-Kaloustian, Semiramis, Brooijmans, Natasja, Mallon, Robert, Hollander, Irwin, Feldberg, L

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 3.79 MB

english, 2010

46

Discovery of Potent and Selective Inhibitors of the Mammalian Target of Rapamycin (mTOR) Kinase

Nowak, Pawel, Cole, Derek C., Brooijmans, Natasja, Bursavich, Matthew G., Curran, Kevin J., Ellingboe, John W., Gibbons, James J., Hollander, Irwin, Hu, YongBo, Kaplan, Joshua, Malwitz, David J., Tora

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.90 MB

english, 2009

47

Endotoxin-induced fetal growth retardation in the pregnant guinea pig

Beckmann, Ilse, Meisel-Mikolajczyk, Felicja, Leszczynski, Piotr, Brooijmans, Miriam, Wallenburg, Henk C.S.

Journal:

American Journal of Obstetrics and Gynecology

Year:

1993

Language:

english

File:

PDF, 718 KB

english, 1993

48

[IEEE 2007 15th IEEE-NPSS Real-Time Conference - Batavia, IL, USA (2007.04.29-2007.05.4)] 2007 15th IEEE-NPSS Real-Time Conference - The DZERO Level 3 DAQ System: Operation and Upgrades

Garcia-Bellido, Aran, Bose, Tulika, Brooijmans, Gustaaf, Chapin, Doug, Cutts, David, Fuess, Stuart, Gadfort, Thomas, Haas, Andrew, Lee, William, Rechenmacher, Ron, Snyder, Scott, Watts, Gordon, Xie, Y

Year:

2007

Language:

english

File:

PDF, 849 KB

english, 2007

49

ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin: Design and Synthesis of Highly Potent and Selective Pyrazolopyrimidines

Zask, Arie, Verheijen, Jeroen C., Curran, Kevin, Kaplan, Joshua, Richard, David J., Nowak, Pawel, Malwitz, David J., Brooijmans, Natasja, Bard, Joel, Svenson, Kristine, Lucas, Judy, Toral-Barza, Lourd

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.32 MB

english, 2009

50

The DZERO level 3 data acquisition system

Angstadt, R., Brooijmans, G., Chapin, D., Clements, M., Cutts, D., Haas, A., Hauser, R., Johnson, M., Kulyavtsev, A., Mattingly, S.E.K., Mulders, M., Padley, P., Petravick, D., Rechenmacher, R., Snyde

Journal:

IEEE Transactions on Nuclear Science

Year:

2004

Language:

english

File:

PDF, 103 KB

english, 2004

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