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1

Enzymatic conversion of lignin into renewable chemicals

Bugg, Timothy DH, Rahmanpour, Rahman

Journal:

Current Opinion in Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.38 MB

english, 2015

2

Dioxygenase enzymes: catalytic mechanisms and chemical models

Timothy D.H. Bugg

Journal:

Year:

2003

Language:

english

File:

PDF, 1.55 MB

english, 2003

3

Lignocellulose degradation mechanisms across the Tree of Life

Cragg, Simon M, Beckham, Gregg T, Bruce, Neil C, Bugg, Timothy DH, Distel, Daniel L, Dupree, Paul, Etxabe, Amaia Green, Goodell, Barry S, Jellison, Jody, McGeehan, John E, McQueen-Mason, Simon J, Schn

Journal:

Current Opinion in Chemical Biology

Year:

2015

Language:

english

File:

PDF, 3.15 MB

english, 2015

4

Delignification and Enhanced Gas Release from Soil Containing Lignocellulose by Treatment with Bacterial Lignin Degraders

Rashid, Goran M.M., Duran-Pena, Maria Jesus, Rahmanpour, Rahman, Sapsford, Devin, Bugg, Timothy D.H.

Journal:

Journal of Applied Microbiology

Year:

2017

Language:

english

File:

PDF, 794 KB

english, 2017

5

Dioxygenase Enzymes: Catalytic Mechanisms and Chemical Models

Timothy D. H. Bugg

Journal:

Year:

2003

File:

PDF, 50 KB

2003

6

ChemInform Abstract: Antimicrobial Nucleoside Antibiotics Targeting Cell Wall Assembly: Recent Advances in Structure—Function Studies and Nucleoside Biosynthesis

Michael Winn, Rebecca J. M. Goss, Ken-ichi Kimura, Timothy D. H. Bugg

Journal:

Year:

2010

File:

PDF, 16 KB

2010

7

Oxygenases: mechanisms and structural motifs for O2 activation

Timothy D.H Bugg

Journal:

Current Opinion in Chemical Biology

Year:

2001

Language:

english

File:

PDF, 118 KB

english, 2001

8

10.1038/46052

Bestor, Timothy H., Xu, Guo-Liang, Bourc'his, Déborah, Hsieh, Chih-Lin, Tommerup, Niels, Bugge, Merete, Hulten, Maj, Qu, Xiaoyan, Russo, James J., Viegas-Péquignot, Evani

Journal:

Year:

1999

Language:

english

File:

PDF, 253 KB

english, 1999

9

Pathways for degradation of lignin in bacteria and fungi

Bugg, Timothy D. H., Ahmad, Mark, Hardiman, Elizabeth M., Rahmanpour, Rahman

Journal:

Natural Product Reports

Year:

2011

Language:

english

File:

PDF, 648 KB

english, 2011

10

Development of novel assays for lignin degradation: comparative analysis of bacterial and fungal lignin degraders

Ahmad, Mark, Taylor, Charles R., Pink, David, Burton, Kerry, Eastwood, Daniel, Bending, Gary D., Bugg, Timothy D. H.

Journal:

Molecular BioSystems

Year:

2010

Language:

english

File:

PDF, 694 KB

english, 2010

11

Antimicrobial nucleoside antibiotics targeting cell wall assembly: Recent advances in structure–function studies and nucleoside biosynthesis

Goss, Rebecca J. M., Kimura, Ken-ichi, Bugg, Timothy D. H., Winn, Michael

Journal:

Natural Product Reports

Year:

2010

Language:

english

File:

PDF, 778 KB

english, 2010

12

Bacterial cell wall assembly: still an attractive antibacterial target

Timothy D.H. Bugg, Darren Braddick, Christopher G. Dowson, David I. Roper

Journal:

Trends in Biotechnology

Year:

2011

Language:

english

File:

PDF, 639 KB

english, 2011

13

Regiospecific Ester Hydrolysis by Orange Peel Esterase - An Undergraduate Experiment.

Bugg, Timothy D.H., Lewin, Andrew M., Catlin, Eric R.

Journal:

Journal of Chemical Education

Year:

1997

Language:

english

File:

PDF, 170 KB

english, 1997

14

Identification of vancomycin resistance protein VanA as a D-alanine:D-alanine ligase of altered substrate specificity

Bugg, Timothy D. H., Dutka-Malen, Sylvie, Arthur, Michel, Courvalin, Patrice, Walsh, Christopher T.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.57 MB

english, 1991

15

Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA

Bugg, Timothy D. H., Wright, Gerard D., Dutka-Malen, Sylvie, Arthur, Michel, Courvalin, Patrice, Walsh, Christopher T.

Journal:

Year:

1991

Language:

english

File:

PDF, 2.06 MB

english, 1991

16

Periodic root branching in Arabidopsis requires synthesis of an uncharacterized carotenoid derivative

Van Norman, Jaimie M., Zhang, Jingyuan, Cazzonelli, Christopher I., Pogson, Barry J., Harrison, Peter J., Bugg, Timothy D. H., Chan, Kai Xun, Thompson, Andrew J., Benfey, Philip N.

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 1.58 MB

english, 2014

17

Enzymatic Breakdown of Poly-γ- d -glutamic Acid in Bacillus licheniformis : Identification of a Polyglutamyl γ-Hydrolase Enzyme

King, Elizabeth C., Blacker, A. John, Bugg, Timothy D. H.

Journal:

Biomacromolecules

Year:

2000

Language:

english

File:

PDF, 240 KB

english, 2000

18

Extradiol Oxidative Cleavage of Catechols by Ferrous and Ferric Complexes of 1,4,7-Triazacyclononane: Insight into the Mechanism of the Extradiol Catechol Dioxygenases

Lin, Gang, Reid, Gillian, Bugg, Timothy D. H.

Journal:

Journal of the American Chemical Society

Year:

2001

Language:

english

File:

PDF, 169 KB

english, 2001

19

Enzymatic cleavage of aromatic rings: mechanistic aspects of the catechol dioxygenases and later enzymes of bacterial oxidative cleavage pathways

D. H. Bugg, Timothy, J. Winfield, Christopher

Journal:

Natural Product Reports

Year:

1998

Language:

english

File:

PDF, 648 KB

english, 1998

20

Identification of a Novel Inhibition Site in Translocase MraY Based upon the Site of Interaction with Lysis Protein E from Bacteriophage ϕX174

Rodolis, Maria T., Mihalyi, Agnes, O'Reilly, Amy, Slikas, Justinas, Roper, David I., Hancock, Robert E. W., Bugg, Timothy D. H.

Journal:

Year:

2014

Language:

english

File:

PDF, 828 KB

english, 2014

21

Characterisation of Dyp-type peroxidases from Pseudomonas fluorescens Pf-5: Oxidation of Mn(II) and polymeric lignin by Dyp1B

Rahmanpour, Rahman, Bugg, Timothy D.H.

Journal:

Archives of Biochemistry and Biophysics

Year:

2015

Language:

english

File:

PDF, 914 KB

english, 2015

22

Chemical intervention in bacterial lignin degradation pathways: Development of selective inhibitors for intradiol and extradiol catechol dioxygenases

Sainsbury, Paul D., Mineyeva, Yelena, Mycroft, Zoe, Bugg, Timothy D.H.

Journal:

Bioorganic Chemistry

Year:

2015

Language:

english

File:

PDF, 1.51 MB

english, 2015

23

Bacterial SBP56 identified as a Cu-dependent methanethiol oxidase widely distributed in the biosphere

Eyice, Özge, Myronova, Nataliia, Pol, Arjan, Carrión, Ornella, Todd, Jonathan D, Smith, Tom J, Gurman, Stephen J, Cuthbertson, Adam, Mazard, Sophie, Mennink-Kersten, Monique ASH, Bugg, Timothy DH, And

Journal:

The ISME Journal

Year:

2018

Language:

english

File:

PDF, 1.35 MB

english, 2018

24

Covalent modification in aqueous solution of poly-γ-D-glutamic acid from bacillus licheniformis

Elizabeth C. King, William J. Watkins, A. John Blacker, Timothy D. H. Bugg

Journal:

Journal of Polymer Science Part A: Polymer Chemistry

Year:

1998

Language:

english

File:

PDF, 119 KB

english, 1998

25

Antibiotic Action and Peptidoglycan Formation on Tethered Lipid Bilayer Membranes

Michael J. Spencelayh, Yaling Cheng, Richard J. Bushby, Timothy D. H. Bugg, Jian-jun Li, Peter J. F. Henderson, John O'Reilly, Stephen D. Evans

Journal:

Angewandte Chemie

Year:

2006

Language:

english

File:

PDF, 253 KB

english, 2006

26

Antibiotic Action and Peptidoglycan Formation on Tethered Lipid Bilayer Membranes

Michael J. Spencelayh, Yaling Cheng, Richard J. Bushby, Timothy D. H. Bugg, Jian-jun Li, Peter J. F. Henderson, John O'Reilly, Stephen D. Evans

Journal:

Angewandte Chemie International Edition

Year:

2006

Language:

english

File:

PDF, 254 KB

english, 2006

27

Directed Evolution of a Non-Heme-Iron-Dependent Extradiol Catechol Dioxygenase: Identification of Mutants with Intradiol Oxidative Cleavage Activity

Janne Schlosrich, Kirstin L. Eley, Patrick J. Crowley, Timothy D. H. Bugg

Journal:

Year:

2006

Language:

english

File:

PDF, 495 KB

english, 2006

28

Catalytic Promiscuity in the α/β-Hydrolase Superfamily: Hydroxamic Acid Formation, CC Bond Formation, Ester and Thioester Hydrolysis in the CC Hydrolase Family

Chen Li, Melanie Hassler, Timothy D. H. Bugg

Journal:

Year:

2008

Language:

english

File:

PDF, 358 KB

english, 2008

29

Biomimetic Formation of 2-Tropolones by Dioxygenase-Catalysed Ring Expansion of Substituted 2,4-Cyclohexadienones

Meite Xin, Timothy D. H. Bugg

Journal:

Year:

2010

Language:

english

File:

PDF, 274 KB

english, 2010

30

ChemInform Abstract: Role of the Enamide Linkage of Nucleoside Antibiotic Mureidomycin A: Synthesis and Reactivity of Enamide-Containing Analogues.

Caragh A. Gentle, Timothy D. H. Bugg

Journal:

Year:

1999

File:

PDF, 24 KB

1999

31

ChemInform Abstract: Structure—Function Studies on Nucleoside Antibiotic Mureidomycin A: Synthesis of 5′-Functionalized Uridine Models.

Caragh A. Gentle, Stephen A. Harrison, Masatoshi Inukai, Timothy D. H. Bugg

Journal:

Year:

1999

File:

PDF, 24 KB

1999

32

ChemInform Abstract: Use of Trityl Thiol for Stereoselective Thioester Synthesis: A New Preparation of (S)-Thiolactic Acid.

Ross L. Harding, Timothy D. H. Bugg

Journal:

Year:

2000

File:

PDF, 27 KB

2000

33

ChemInform Abstract: A Biomimetic Model Reaction for the Extradiol Catechol Dioxygenases.

Gang Lin, Gillian Reid, Timothy D. H. Bugg

Journal:

Year:

2000

File:

PDF, 26 KB

2000

34

ChemInform Abstract: Solving the Riddle of the Intradiol and Extradiol Catechol Dioxygenases: How Do Enzymes Control Hydroperoxide Rearrangements?

Timothy D. H. Bugg, Gang Lin

Journal:

Year:

2001

File:

PDF, 26 KB

2001

35

ChemInform Abstract: Extradiol Oxidative Cleavage of Catechols by Ferrous and Ferric Complexes of 1,4,7-Triazacyclononane: Insight into the Mechanism of the Extradiol Catechol Dioxygenases.

Gang Lin, Gillian Reid, Timothy D. H. Bugg

Journal:

Year:

2001

File:

PDF, 26 KB

2001

36

ChemInform Abstract: The Development of Mechanistic Enzymology in the 20th Century

Timothy D. H. Bugg

Journal:

Year:

2001

File:

PDF, 25 KB

2001

37

Thioester Analogues of Peptidoglycan Fragment MurNAc-L-Ala-γ-D-Glu as Substrates for Peptidoglycan Hydrolase MurNAc-L-Ala Amidase.

Ross L. Harding, Joanne Henshaw, Joannah Tilling, Timothy D. H. Bugg

Journal:

Year:

2002

File:

PDF, 29 KB

2002

38

Recent Advances in Antimicrobial Nucleoside Antibiotics Targeting Cell Wall Biosynthesis

Ken-ichi Kimura, Timothy D. H. Bugg

Journal:

Year:

2003

File:

PDF, 4 KB

2003

39

Stereochemistry of the Reaction Catalyzed by 2-Hydroxy-6-keto-6-phenyl-hexa-2,4-dienoic Acid 5,6-Hydrolase (BphD).

Jian-Jun Li, Timothy D. H. Bugg

Journal:

Year:

2005

File:

PDF, 14 KB

2005

40

ChemInform Abstract: Pathways for Degradation of Lignin in Bacteria and Fungi

Timothy D. H. Bugg, Mark Ahmad, Elizabeth M. Hardiman, Rahman Rahmanpour

Journal:

Year:

2012

File:

PDF, 18 KB

2012

41

Diverse catalytic activities in the αβ-hydrolase family of enzymes: activation of H2O, HCN, H2O2, and O2

Timothy D.H. Bugg

Journal:

Bioorganic Chemistry

Year:

2004

Language:

english

File:

PDF, 1.70 MB

english, 2004

42

Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors

Elena Cressina, Adrian J. Lloyd, Gianfranco De Pascale, B. James Mok, Stephen Caddick, David I. Roper, Christopher G. Dowson, Timothy D.H. Bugg

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 931 KB

english, 2009

43

Inhibition of Escherichia coli glycosyltransferase MurG and Mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics

Amy E. Trunkfield, Sudagar S. Gurcha, Gurdyal S. Besra, Timothy D.H. Bugg

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 950 KB

english, 2010

44

Adenosine phosphonate inhibitors of lipid II: Alanyl tRNA ligase MurM from Streptococcus pneumoniae

Elena Cressina, Adrian J. Lloyd, Gianfranco De Pascale, David I. Roper, Christopher G. Dowson, Timothy D.H. Bugg

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 146 KB

english, 2007

45

Non-heme iron-dependent dioxygenases: unravelling catalytic mechanisms for complex enzymatic oxidations

Timothy DH Bugg, S Ramaswamy

Journal:

Current Opinion in Chemical Biology

Year:

2008

Language:

english

File:

PDF, 1.25 MB

english, 2008

46

The emerging role for bacteria in lignin degradation and bio-product formation

Timothy DH Bugg, Mark Ahmad, Elizabeth M Hardiman, Rahul Singh

Journal:

Current Opinion in Biotechnology

Year:

2011

Language:

english

File:

PDF, 580 KB

english, 2011

47

Use of trityl thiol for stereoselective thioester synthesis: a new preparation of (S)-thiolactic acid

Ross L Harding, Timothy D.H Bugg

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 71 KB

english, 2000

48

Specificity of E. Coli shikimate dehydrogenase towards analogues of 3-dehydroshikimic acid

Timothy D.H. Bugg, Chris Abell, John R. Coggins

Journal:

Tetrahedron Letters

Year:

1988

Language:

english

File:

PDF, 241 KB

english, 1988

49

Affinity labelling of E. Coli dehydroquinase

Timothy D.H. Bugg, Chris Abell, John R. Coggins

Journal:

Tetrahedron Letters

Year:

1988

Language:

english

File:

PDF, 232 KB

english, 1988

50

Biological Properties of N-Acyl and N-Haloacetyl Neuraminic Acids: Processing by Enzymes of Sialic Acid Metabolism, and Interaction with Influenza Virus

Andrew J Humphrey, Claire Fremann, Peter Critchley, Yanina Malykh, Roland Schauer, Timothy D.H Bugg

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 375 KB

english, 2002

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