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51

Effect of chronic treatment with neuroleptics on stress responsivity in an animal model for neurodevelopmental psychopathological disorders

J. Terpstra, C.C. Gispen-De Wied, B. Fabriek, M.H. Broekhoven, H. Spierenburg, R.S. Kahn, J.M. Van Ree, V.M. Wiegant

Journal:

Schizophrenia Research

Year:

2003

Language:

english

File:

PDF, 249 KB

english, 2003

52

164 - Cortisol response to a psychosocial stressor in schizophrenia

Christine C. Gispen-de Wied, Lucres M.C. Jansen, Jeroen A. van der Linden, René S. Kahn

Journal:

Schizophrenia Research

Year:

1997

Language:

english

File:

PDF, 111 KB

english, 1997

53

616 - The partial NMDA agonist D-cycloserine stimulates LH secretion in healthy volunteers

Bart N.M. Van Berckel, Claudia Lipsch, Christine Gispen-de Wied, Herman J. Wynne, Rien A. Blankenstein, Jan M. van Ree, René S. Kahn

Journal:

Schizophrenia Research

Year:

1997

Language:

english

File:

PDF, 192 KB

english, 1997

54

736 - Second-trimester exposure to maternal stress is a possible risk factor for psychotic illness in the child

J.P. Selten, R. van Duursen, Y. van der Graaf, C. Gispen-de Wied, R.S. Kahn

Journal:

Schizophrenia Research

Year:

1997

Language:

english

File:

PDF, 118 KB

english, 1997

55

No increase in abnormalities in the clinical neuroradiological exam in schizophrenia

H.E. Hulshoff Pol, C.C. Gispen-de Wied, L.M. Ramos, J. Van der Linden, W. Cahn, J.P. Selten, C. Van Oel, W.F.C. Baare, W.G. Staal, W.P.Th.M. Mali, R.S. Kahn

Journal:

Schizophrenia Research

Year:

1998

Language:

english

File:

PDF, 100 KB

english, 1998

56

Psychotic illness after prenatal exposure to the 1953 Dutch Flood Disaster

Jean-Paul Selten, Yolanda van der Graaf, Rozemarijn van Duursen, Christien C Gispen-de Wied, René S Kahn

Journal:

Schizophrenia Research

Year:

1999

Language:

english

File:

PDF, 61 KB

english, 1999

57

Blunted cortisol response to a psychosocial stressor in schizophrenia

Lucres M.C. Jansen, Christine C. Gispen-de Wied, Petra J. Gademan, Rogier C.J. De Jonge, Jeroen A. van der Linden, René S. Kahn

Journal:

Schizophrenia Research

Year:

1998

Language:

english

File:

PDF, 125 KB

english, 1998

58

Maladaptation to stress in schizophrenia

C.C. Gispen-de Wied

Journal:

European Neuropsychopharmacology

Year:

2000

Language:

english

File:

PDF, 327 KB

english, 2000

59

Differentiation between autism and multiple complex developmentadisorder in the response to psychosocial stress

L.M.C. Jansen, C.C. Gispen-de Wied, H. Van Engeland

Journal:

European Neuropsychopharmacology

Year:

2000

Language:

english

File:

PDF, 207 KB

english, 2000

60

Attenuated stress responsiveness in an animal model for neurodevelopmental psychopathological disorders

Jeroen Terpstra, Christine C Gispen-De Wied, Mark H Broekhoven, Ank C Frankhuijzen, René S Kahn, Jan M van Ree, Victor M Wiegant

Journal:

European Neuropsychopharmacology

Year:

2003

Language:

english

File:

PDF, 232 KB

english, 2003

61

Factors influencing non-approval of new drugs in Europe

Putzeist, Michelle, Mantel-Teeuwisse, Aukje K., Aronsson, Bo, Rowland, Malcolm, Gispen-de Wied, Christine C., Vamvakas, Spiros, Hoes, Arno W., Leufkens, Hubert G. M., Eichler, Hans-Georg

Journal:

Nature Reviews Drug Discovery

Year:

2012

Language:

english

File:

PDF, 239 KB

english, 2012

62

From molecule to market access: Drug regulatory science as an upcoming discipline

Gispen-de Wied, Christine C., Leufkens, Hubertus G.M.

Journal:

European Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 367 KB

english, 2013

63

Stimulation and inhibition of the pituitary-adrenal axis in depressed patients and control subjects

Gispen-De Wied, C.C, Van Ree, J.M

Journal:

European Neuropsychopharmacology

Year:

1991

Language:

english

File:

PDF, 338 KB

english, 1991

64

Stimulation of the pituitary-adrenal system with graded doses of CRH and low dose vasopressin infusion in depressed patients and healthy subjects: a pilot study

Wied, C.C.Gispen-de, Kok, F.W., Koppeschaar, H.P.F., Wynne, H.J., Westenberg, H.G.M., Thijssen, J.H.H., van Ree, J.M.

Journal:

European Neuropsychopharmacology

Year:

1993

Language:

english

File:

PDF, 637 KB

english, 1993

65

The risk-based approach to ATMP development – Generally accepted by regulators but infrequently used by companies

Kooijman, M., van Meer, P.J.K., Gispen-de Wied, C.C., Moors, E.H.M., Hekkert, M.P., Schellekens, H.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2013

Language:

english

File:

PDF, 259 KB

english, 2013

66

Physical exercise and pituitary-adrenal function in children with autistic-like disorder: Relevance to schizophrenia

Gispen-de Wied, C.C., Jansen, L.M.C., van der Gaag, R.J., van Engeland, H.

Journal:

Schizophrenia Research

Year:

1996

Language:

english

File:

PDF, 89 KB

english, 1996

67

Cognition in schizophrenia: Summary Nice Consultation Meeting 2012

Nutt, David, Gispen-de Wied, Christine C, Arango, Celso, Keefe, Richard SE, Penadés, Rafael, Murphy, Declan G, Robbins, Trevor W, Sahakian, Barbara J

Journal:

European Neuropsychopharmacology

Year:

2013

Language:

english

File:

PDF, 408 KB

english, 2013

68

EU marketing authorization review of orphan and non-orphan drugs does not differ

Putzeist, M., Mantel-Teeuwisse, A.K., Llinares, J., Gispen-De Wied, C.C., Hoes, A.W., Leufkens, H.G.M.

Journal:

Drug Discovery Today

Year:

2013

Language:

english

File:

PDF, 243 KB

english, 2013

69

Stimulation of the pituitary-adrenal axis with a low dose [Arg8]-vasopressin in depressed patients and healthy subjects

Gispen-de Wied, Christine C., Westenberg, Herman G.M., Koppeschaar, Hans P.F., Thijssen, Jos H.H., van Ree, Jan M.

Journal:

European Neuropsychopharmacology

Year:

1992

Language:

english

File:

PDF, 706 KB

english, 1992

70

Differentiation between Autism and Multiple Complex Developmental Disorder in Response to Psychosocial Stress

Jansen, Lucres MC, Gispen-de Wied, Christine C, van der Gaag, Rutger-Jan, van Engeland, Herman

Journal:

Neuropsychopharmacology

Year:

2003

Language:

english

File:

PDF, 137 KB

english, 2003

71

The Distribution of Congenital Anomalies Within the VACTERL Association Among Tumor Necrosis Factor Antagonist-exposed Pregnancies Is Similar to the General Population

CRIJNS, H. J. M. J., JENTINK, J., GARNE, E., GISPEN-de WIED, C. C., STRAUS, S. M. J. M., de JONG-van den BERG, L. T. W.

Journal:

The Journal of Rheumatology

Year:

2011

Language:

english

File:

PDF, 142 KB

english, 2011

72

Immunogenicity of mAbs in non-human primates during nonclinical safety assessment

van Meer, Peter J.K., Kooijman, Marlous, Brinks, Vera, Gispen-de Wied, Christine C., Silva-Lima, Beatriz, Moors, Ellen H.M., Schellekens, Huub

Journal:

Year:

2013

Language:

english

File:

PDF, 165 KB

english, 2013

73

Contribution of animal studies to evaluate the similarity of biosimilars to reference products

van Meer, Peter J.K., Ebbers, Hans C., Kooijman, Marlous, Gispen-de Wied, Christine C., Silva-Lima, Beatriz, Moors, Ellen H.M., Schellekens, Huub

Journal:

Drug Discovery Today

Year:

2015

Language:

english

File:

PDF, 308 KB

english, 2015

74

Placebo response in antipsychotic trials of patients with acute mania

Welten, C.C.M., Koeter, M.W.J., Wohlfarth, T., Storosum, J.G., van den Brink, W., Gispen-de Wied, C.C., Leufkens, H.G.M., Denys, D.A.J.P.

Journal:

European Neuropsychopharmacology

Year:

2015

Language:

english

File:

PDF, 471 KB

english, 2015

75

Hyperglycemia and Diabetes in Patients With Schizophrenia or Schizoaffective Disorders

Cohen, D., Stolk, R. P., Grobbee, D. E., Gispen-de Wied, C. C.

Journal:

Year:

2006

Language:

english

File:

PDF, 104 KB

english, 2006

76

No effects of l-dopa and bromocriptine on psychophysiological parameters of human selective attention

Oranje, B., Gispen-de Wied, C. C., Westenberg, H. G. M., Kemner, C., Verbaten, M. N., Kahn, R. S.

Journal:

Journal of Psychopharmacology

Year:

2006

Language:

english

File:

PDF, 149 KB

english, 2006

77

Haloperidol counteracts the ketamine-induced disruption of processing negativity, but not that of the P300 amplitude

Oranje, Bob, Gispen-de Wied, Christine C., Westenberg, Herman G. M., Kemner, Chantal, Verbaten, Marinus N., Kahn, René S.

Journal:

The International Journal of Neuropsychopharmacology

Year:

2009

Language:

english

File:

PDF, 145 KB

english, 2009

78

Efficacy of drug treatment for acute mania differs across geographic regions: An individual patient data meta-analysis of placebo-controlled studies

Welten, C. C., Koeter, M., Wohlfarth, T., Storosum, J., van den Brink, W., Gispen-de Wied, C., Leufkens, H., Denys, D.

Journal:

Journal of Psychopharmacology

Year:

2015

Language:

english

File:

PDF, 876 KB

english, 2015

79

Net gain analysis, an addition to responder analysis – The case of antipsychotic treatment of acute mania

Welten, C.C.M., Koeter, M.W.J., Wohlfarth, T.D., Storosum, J.G., van den Brink, W., Gispen-de Wied, C.C., Leufkens, H.G.M., Denys, D.A.J.P.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 554 KB

english, 2015

80

What regulatory science can bring for CNS drug development

Gispen-de Wied, Christine, Stoyanova-Beninska, Violeta

Journal:

European Neuropsychopharmacology

Year:

2015

Language:

english

File:

PDF, 298 KB

english, 2015

81

CNS biomarkers: Potential from a regulatory perspective

Isaac, Maria, Gispen-de Wied, Christine

Journal:

European Neuropsychopharmacology

Year:

2015

Language:

english

File:

PDF, 800 KB

english, 2015

82

Suicide Risk in Placebo-Controlled Trials of Treatment for Acute Manic Episode and Prevention of Manic-Depressive Episode

Storosum, Jitschak G., Wohlfarth, Tamar, Gispen-de Wied, Christine C., Linszen, Don H., Gersons, Berthold P.R., van Zwieten, Barbara J., van den Brink, Wim

Journal:

American Journal of Psychiatry

Year:

2005

Language:

english

File:

PDF, 95 KB

english, 2005

83

Effects of Typical and Atypical Antipsychotics on the Prepulse Inhibition of the Startle Reflex in Patients With Schizophrenia

Oranje, Bob, van Oel, Clarine J., Gispen-de Wied, Christine C., Verbaten, Marinus N., Kahn, René S.

Journal:

Journal of Clinical Psychopharmacology

Year:

2002

Language:

english

File:

PDF, 469 KB

english, 2002

84

HTR2C Gene Polymorphisms and the Metabolic Syndrome in Patients With Schizophrenia

Mulder, Hans, Cohen, Dan, Scheffer, Hans, Gispen-de Wied, Christine, Arends, Johan, Wilmink, Frederik W., Franke, Barbara, Egberts, Antoine C.G.

Journal:

Journal of Clinical Psychopharmacology

Year:

2009

Language:

english

File:

PDF, 152 KB

english, 2009

85

Letter to the Editor

STOROSUM, JITSCHAK G., WOHLFARTH, TAMAR, GISPEN-de WIED, CHRISTIEN C., LINSZEN, DON H., GERSONS, BETHOLD P.R., van ZWIETEN, BARBARA J., van den BRINK, WIM

Journal:

American Journal of Psychiatry

Year:

2006

Language:

english

File:

PDF, 56 KB

english, 2006

86

Prenatal Exposure to Famine and Brain Morphology in Schizophrenia

Hulshoff Pol, Hilleke E., Hoek, Hans W., Susser, Ezra, Brown, Alan S., Dingemans, Alexandra, Schnack, Hugo G., van Haren, Neeltje E.M., Pereira Ramos, Lino Moreira, Gispen-de Wied, Christine C., Kahn,

Journal:

American Journal of Psychiatry

Year:

2000

Language:

english

File:

PDF, 76 KB

english, 2000

87

Factors Contributing to the Efficacy-Effectiveness Gap in the Case of Orphan Drugs for Metabolic Diseases

Schuller, Y., Hollak, C. E. M., Gispen-de Wied, C. C., Stoyanova-Beninska, V., Biegstraaten, M.

Journal:

Year:

2017

Language:

english

File:

PDF, 478 KB

english, 2017

88

European regulatory use and impact of subgroup evaluation in marketing authorisation applications

Tanniou, Julien, Teerenstra, Steven, Hassan, Sagal, Elferink, Andre, van der Tweel, Ingeborg, Gispen-de Wied, Christine, Roes, Kit C.B.

Journal:

Drug Discovery Today

Year:

2017

Language:

english

File:

PDF, 178 KB

english, 2017

89

Autism and autistic-like disorders: the hypothalamic-pituita-ry-adrenal system as a model for research

Jansen, L.M.C., Wied, C.C. Gispen-De, Engeland, H. Van

Journal:

Acta Neuropsychiatrica

Year:

1995

File:

PDF, 1.11 MB

1995

90

Regulatory Scientific Advice on Non-Inferiority Drug Trials

Wangge, Grace, Putzeist, Michelle, Knol, Mirjam J., Klungel, Olaf H., Gispen-De Wied, Christine C., de Boer, Antonius, Hoes, Arno W., Leufkens, Hubert G., Mantel-Teeuwisse, Aukje K., Mintzes, Barbara

Journal:

Year:

2013

Language:

english

File:

PDF, 531 KB

english, 2013

91

Dose-Finding Studies Among Orphan Drugs Approved in the EU: A Retrospective Analysis

Schuller, Yvonne, Gispen-de Wied, Christine, Hollak, Carla E. M., Leufkens, Hubertus G. M., Stoyanova-Beninska, Violeta

Journal:

Journal of Clinical Pharmacology

Year:

2018

Language:

english

File:

PDF, 246 KB

english, 2018

92

Commentary on ‘Gender differences in clinical registration trials; is there a real problem?’ by Labots et al .

Gispen-de Wied, Christine, de Boer, Anthonius

Journal:

British Journal of Clinical Pharmacology

Year:

2018

Language:

english

File:

PDF, 92 KB

english, 2018

93

Ethics in clinical trial regulation: ethically relevant issues from EMA inspection reports

Bernabe, RDLC, van Thiel, GJMW, Breekveldt, NS, Gispen-de Wied, CC, van Delden, JJM

Journal:

Current Medical Research and Opinion

Year:

2018

Language:

english

File:

PDF, 796 KB

english, 2018

94

Drug Shortages From the Perspectives of Authorities and Pharmacy Practice in the Netherlands: An Observational Study

Postma, Doerine J., De Smet, Peter A. G. M., Gispen-de Wied, Christine C., Leufkens, Hubert G. M., Mantel-Teeuwisse, Aukje K.

Journal:

Frontiers in Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.89 MB

english, 2018

95

Regulatory and Health Technology Assessment Considerations for Disease-Modifying Drugs in Alzheimer’s Disease

Bouvy, Jacoline C., Jonsson, Pall, O’Rourke, Diana, Chadha, Antonella Santuccione, Hedberg, Niklas, Makady, Amr, Xoxi, Entela, Wied, Christine Gispen-de, Schiel, Anja, Long, Raj, Gallacher, John

Journal:

Year:

2018

Language:

english

File:

PDF, 808 KB

english, 2018

96

Baseline imbalances and clinical outcomes of atypical antipsychotics in dementia: A meta-epidemiological study of randomized trials

Hulshof, Tessa A., Zuidema, Sytse U., van Meer, Peter J.K., Gispen-de Wied, Christine C., Luijendijk, Hendrika J.

Journal:

International Journal of Methods in Psychiatric Research

Year:

2018

Language:

english

File:

PDF, 377 KB

english, 2018

97

A standardised framework to identify optimal animal models for efficacy assessment in drug development

S. Ferreira, Guilherme, Veening-Griffioen, Désirée H., Boon, Wouter P. C., Moors, Ellen H. M., Gispen-de Wied, Christine C., Schellekens, Huub, van Meer, Peter J. K., Macleod, Malcolm R.

Journal:

Year:

2019

Language:

english

File:

PDF, 945 KB

english, 2019

98

Are some animal models more equal than others? A case study on the translational value of animal models of efficacy for Alzheimer'’s disease

Veening-Griffioen, Désirée H., Ferreira, Guilherme S., van Meer, Peter J.K., Boon, Wouter P.C., Gispen-de Wied, Christine C., Moors, Ellen H.M., Schellekens, Huub

Journal:

European Journal of Pharmacology

Year:

2019

Language:

english

File:

PDF, 860 KB

english, 2019

99

Are some animal models more equal than others? A case study on the translational value of animal models of efficacy for Alzheimer'’s disease

Veening-Griffioen, Désirée H., Ferreira, Guilherme S., van Meer, Peter J.K., Boon, Wouter P.C., Gispen-de Wied, Christine C., Moors, Ellen H.M., Schellekens, Huub

Journal:

European Journal of Pharmacology

Year:

2019

File:

PDF, 860 KB

2019

100

Determination of dexamethasone in saliva

Thijssen, J H, Gispen-de Wied, C C, van Heeswijk, G M, Veeman, W

Journal:

Clinical Chemistry

Year:

1996

File:

PDF, 790 KB

1996

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