Checler, F: search on Z-Library

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51

Glioma tumor grade correlates with parkin depletion in mutant p53-linked tumors and results from loss of function of p53 transcriptional activity

Viotti, J, Duplan, E, Caillava, C, Condat, J, Goiran, T, Giordano, C, Marie, Y, Idbaih, A, Delattre, J-Y, Honnorat, J, Checler, F, Alves da Costa, C

Journal:

Year:

2014

Language:

english

File:

PDF, 2.81 MB

english, 2014

52

Melatonin stimulates the nonamyloidogenic processing of β APP through the positive transcriptional regulation of ADAM10 and ADAM17

Shukla, Mayuri, Htoo, Htut Htut, Wintachai, Phitchayapak, Hernandez, Jean-Francois, Dubois, Claire, Postina, Rolf, Xu, Huaxi, Checler, Frédéric, Smith, Duncan R., Govitrapong, Piyarat, Vincent, Bruno

Journal:

Journal of Pineal Research

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

53

TMP21 Transmembrane Domain Regulates -Secretase Cleavage

Pardossi-Piquard, R., Bohm, C., Chen, F., Kanemoto, S., Checler, F., Schmitt-Ulms, G., St. George-Hyslop, P., Fraser, P. E.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 2.70 MB

english, 2009

54

The Disintegrin ADAM9 Indirectly Contributes to the Physiological Processing of Cellular Prion by Modulating ADAM10 Activity

Cisse, M. A., Sunyach, C., Lefranc-Jullien, S., Postina, R., Vincent, B., Checler, F.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 1.38 MB

english, 2005

55

Protein Kinase A Phosphorylation of the Proteasome: A Contribution to the α-Secretase Pathway in Human Cells

Philippe Marambaud, Sherwin Wilk, Frederic Checler

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 454 KB

english, 1996

56

Amyloid-β42 is preferentially accumulated in muscle fibers of patients with sporadic inclusion-body myositis

Gaetano Vattemi, Anna Nogalska, W. King Engel, Carla D’Agostino, Frederic Checler, Valerie Askanas

Journal:

Acta Neuropathologica

Year:

2009

Language:

english

File:

PDF, 374 KB

english, 2009

57

Amyloid-lowering isocoumarins are not direct inhibitors of γ-secretase

Petit, Agnes, Dumanchin-Njock, Cécile, Andrau, David, da Costa, Cristine Alves, Checler, Frédéric

Journal:

Nature Cell Biology

Year:

2002

Language:

english

File:

PDF, 465 KB

english, 2002

58

Nuclear Factor- B Regulates APP and - and -Secretases Differently at Physiological and Supraphysiological A Concentrations

Chami, L., Buggia-Prevot, V., Duplan, E., Delprete, D., Chami, M., Peyron, J.-F., Checler, F.

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 2.41 MB

english, 2012

59

Purification and characterization of human endopeptidase 3.4.24.16. Comparison with the porcine counterpart indicates a unique cleavage site on neurotensin

B. Vincent, J.P. Vincent, F. Checler

Journal:

Year:

1996

Language:

english

File:

PDF, 782 KB

english, 1996

60

Rat kidney endopeptidase 24.16 : Purification, physico-chemical characteristics and differential specificity towards opiates, tachykinins and neurotensin-related peptides

Hélène BARELLI, Jean-Pierre VINCENT, Frédéric CHECLER

Journal:

Year:

1993

Language:

english

File:

PDF, 1.35 MB

english, 1993

61

Presenilin 2 Deficiency Causes a Mild Pulmonary Phenotype and no Changes in Amyloid Precursor Protein Processing but Enhances the Embryonic Lethal Phenotype of Presenilin 1 Deficiency

An Herreman, Dieter Hartmann, Wim Annaert, Paul Saftig, Katleen Craessaerts, Lutgarde Serneels, Lieve Umans, Vincent Schrijvers, Frederic Checler, Hugo Vanderstichele, Veerle Baekelandt, Ralf Dressel,

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.62 MB

english, 1999

62

Cerebrospinal Aβ11-x and 17-x levels as indicators of mild cognitive impairment and patients’ stratification in Alzheimer’s disease

Abraham, J-D, Promé, S, Salvetat, N, Rubrecht, L, Cobo, S, du Paty, E, Galéa, P, Mathieu-Dupas, E, Ranaldi, S, Caillava, C, Crémer, G-A, Rieunier, F, Robert, P, Molina, F, Laune, D, Checler, F, Fareh,

Journal:

Translational Psychiatry

Year:

2013

Language:

english

File:

PDF, 515 KB

english, 2013

63

The -Secretase-derived N-terminal Product of Cellular Prion, N1, Displays Neuroprotective Function in Vitro and in Vivo

Guillot-Sestier, M.-V., Sunyach, C., Druon, C., Scarzello, S., Checler, F.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 2.93 MB

english, 2009

64

Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons

Alves da Costa, C., Paitel, E., Mattson, M. P., Amson, R., Telerman, A., Ancolio, K., Checler, F.

Journal:

Proceedings of the National Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 429 KB

english, 2002

65

6-Hydroxydopamine but not 1-methyl-4-phenylpyridinium abolishes -synuclein anti-apoptotic phenotype by inhibiting its proteasomal degradation and by promoting its aggregation.

Alves da Costa, C., Dunys, J., Brau, F., Wilk, S., Cappai, R., Checler, F.

Journal:

Journal of Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 631 KB

english, 2013

66

A novel parkin-mediated transcriptional function links p53 to familial Parkinson’s disease

Alves da Costa, Cristina, Checler, Frédéric

Journal:

Year:

2010

Language:

english

File:

PDF, 668 KB

english, 2010

67

APH1 Polar Transmembrane Residues Regulate the Assembly and Activity of Presenilin Complexes

Pardossi-Piquard, R., Yang, S.-P., Kanemoto, S., Gu, Y., Chen, F., Bohm, C., Sevalle, J., Li, T., Wong, P. C., Checler, F., Schmitt-Ulms, G., St. George-Hyslop, P., Fraser, P. E.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 2.26 MB

english, 2009

68

Cellular Prion and its Catabolites in the Brain: Production and Function

Guillot-Sestier, M.-V., Checler, F.

Journal:

Current Molecular Medicine

Year:

2012

Language:

english

File:

PDF, 728 KB

english, 2012

69

Direct α-synuclein promoter transactivation by the tumor suppressor p53

Duplan, Eric, Giordano, Cécile, Checler, Frédéric, Alves da Costa, Cristine

Journal:

Molecular Neurodegeneration

Year:

2016

Language:

english

File:

PDF, 1.12 MB

english, 2016

70

Intraneuronal accumulation of C99 contributes to synaptic alterations, apathy-like behavior, and spatial learning deficits in 3×TgAD and 2×TgAD mice

Bourgeois, Alexandre, Lauritzen, Inger, Lorivel, Thomas, Bauer, Charlotte, Checler, Frédéric, Pardossi-Piquard, Raphaëlle

Journal:

Neurobiology of Aging

Year:

2018

Language:

english

File:

PDF, 5.17 MB

english, 2018

71

Jurkat T cells express a functional neutral endopeptidase activity (CALLA) involved in T cell activation.

Mari, B., Checler, F., Ponzio, G., Peyron, J.F., Manie, S., Farahifar, D., Rossi, B., Auberger, P.

Journal:

The EMBO Journal

Year:

1992

Language:

english

File:

PDF, 2.31 MB

english, 1992

72

The Transcription Factor EB Reduces the Intraneuronal Accumulation of the Beta-Secretase-Derived APP Fragment C99 in Cellular and Mouse Alzheimerâs Disease Models

BÃ©cot, AnaÃ¯s, Pardossi-Piquard, RaphaÃ«lle, Bourgeois, Alexandre, Duplan, Eric, Xiao, Qingli, Diwan, Abhinav, Lee, Jin-Moo, Lauritzen, Inger, Checler, FrÃ©dÃ©ric

Journal:

Year:

2020

File:

PDF, 2.35 MB

2020

73

The multiple paradoxes of presenilins : MINI REVIEW

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 228 KB

english, 2001

74

Degradation of Neurotensin by Rat Brain Synaptic Membranes: Involvement of a Thermolysin-Like Metalloendopeptidase (Enkephalinase), Angiotensin-Converting Enzyme, and Other Unidentified Peptidases

Frederic Checler, Jean-Pierre Vincent, Patrick Kitabgi

Journal:

Journal of Neurochemistry

Year:

1983

Language:

english

File:

PDF, 973 KB

english, 1983

75

High-Affinity Receptor Sites and Rapid Proteolytic Inactivation of Neurotensin in Primary Cultured Neurons

Frédéric Checler, Jean Mazella, Patrick Kitabgi, Jean-Pierre Vincent

Journal:

Journal of Neurochemistry

Year:

1986

Language:

english

File:

PDF, 690 KB

english, 1986

76

Neurotensin and neuromedin N undergo distinct catabolic processes in murine astrocytes and primary cultured neurons

Bruno VINCENT, Jean-Pierre VINCENT, Frédéric CHECLER

Journal:

Year:

1994

Language:

english

File:

PDF, 1.03 MB

english, 1994

77

Behavioral Disturbances without Amyloid Deposits in Mice Overexpressing Human Amyloid Precursor Protein with Flemish (A692G) or Dutch (E693Q) Mutation

Samir Kumar-Singh, Ilse Dewachter, Dieder Moechars, Ursula Lübke, Chris De Jonghe, Chantal Ceuterick, Frédéric Checler, Asha Naidu, Barbara Cordell, Patrick Cras, Christine Van Broeckhoven, Fred Van L

Journal:

Neurobiology of Disease

Year:

2000

Language:

english

File:

PDF, 417 KB

english, 2000

78

S2-02-03: Regulation of Aicd Generation

Frederic Checler

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 55 KB

english, 2008

79

Neuropeptide-hydrolysing activities in synaptosomal fractions from dog ileum myenteric, deep muscular and submucous plexi. Their participation in neurotensin inactivation

Barelli, Hélène, Ahmad, Sultan, Kostka, Peter, Fox, Jo-Ann E.T., Daniel, Edwin E., Vincent, Jean-Pierre, Checler, Frédéric

Journal:

Year:

1989

Language:

english

File:

PDF, 686 KB

english, 1989

80

P3-213

Dunys, Julie, Kawarai, Toshitaka, St. George-Hyslop, Peter, Alves da Costa, Cristine, Checler, Frédéric

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

81

P3-238

Sévalle, Jean, Eyral, Erwan, Hernandez, Jean-François, Martinez, Jean, Checler, Frédéric

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

82

Primary Cultured Neurons Devoid of Cellular Prion Display Lower Responsiveness to Staurosporine through the Control of p53 at Both Transcriptional and Post-transcriptional Levels

Paitel, E., Sunyach, C., Alves da Costa, C., Bourdon, J.-C., Vincent, B., Checler, F.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 766 KB

english, 2004

83

The transcription factor X-box binding protein-1 in neurodegenerative diseases

Dunys, Julie, Duplan, Eric, Checler, Frédéric

Journal:

Molecular Neurodegeneration

Year:

2014

Language:

english

File:

PDF, 381 KB

english, 2014

84

Early Phenotypic Changes in Transgenic Mice That Overexpress Different Mutants of Amyloid Precursor Protein in Brain

Moechars, D., Dewachter, I., Lorent, K., Reverse, D., Baekelandt, V., Naidu, A., Tesseur, I., Spittaels, K., Haute, C. V. D., Checler, F., Godaux, E., Cordell, B., Van Leuven, F.

Journal:

Journal of Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 1.25 MB

english, 1999

85

p53-dependent Aph-1 and Pen-2 Anti-apoptotic Phenotype Requires the Integrity of the -Secretase Complex but Is Independent of Its Activity

Dunys, J., Kawarai, T., Sevalle, J., Dolcini, V., George-Hyslop, P. St., Da Costa, C. A., Checler, F.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 645 KB

english, 2007

86

The extracellular regulated kinase-1 (ERK1) controls regulated -secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein.

Cisse, M., Duplan, E., Guillot-Sestier, M.-V., Rumigny, J., Bauer, C., Pages, G., Orzechowski, H.-D., Slack, B. E., Checler, F., Vincent, B.

Journal:

Journal of Biological Chemistry

Year:

2013

Language:

english

File:

PDF, 622 KB

english, 2013

87

Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription

Duplan, E., Sevalle, J., Viotti, J., Goiran, T., Bauer, C., Renbaum, P., Levy-Lahad, E., Gautier, C. A., Corti, O., Leroudier, N., Checler, F., Alves da Costa, C.

Journal:

Journal of Molecular Cell Biology

Year:

2013

Language:

english

File:

PDF, 391 KB

english, 2013

88

p53 Is Regulated by and Regulates Members of the γ-Secretase Complex

Checler, Frédéric, Dunys, Julie, Pardossi-Piquard, Raphaelle, Alves da Costa, Cristine

Journal:

Neurodegenerative Diseases

Year:

2010

Language:

english

File:

PDF, 235 KB

english, 2010

89

Study on the Putative Contribution of Caspases and the Proteasome to the Degradation of Aph-1a and Pen-2

Dunys, Julie, Kawarai, Toshitaka, Giaime, Emilie, Wilk, Sherwin, Herrant, M., Auberger, P., St. George-Hyslop, Peter, Alves da Costa, Cristine, Checler, Fr&eacute, d&eacute, ric

Journal:

Neurodegenerative Diseases

Year:

2007

Language:

english

File:

PDF, 329 KB

english, 2007

90

Predicting survival in pulmonary hypertension with echocardiography: insights from a French single centre cohort

Moceri, P., Chiche, O., Baudouy, D., Checler, C., Sanfiorenzo, C., Leroy, S., Saady, R., Cerboni, P., Ferrari, E.

Journal:

European Heart Journal

Year:

2013

Language:

english

File:

PDF, 172 KB

english, 2013

91

Catabolism of endogenous and overexpressed APH1a and PEN2: evidence for artifactual involvement of the proteasome in the degradation of overexpressed proteins

Dunys, Julie, Kawarai, Toshitaka, Wilk, Sherwin, St. George-Hyslop, Peter, Alves Da Costa, Cristine, Checler, Frédéric

Journal:

Biochemical Journal

Year:

2006

Language:

english

File:

PDF, 511 KB

english, 2006

92

Fluorimetric assay of the neurotensin-degrading metalloendopeptidase, endopeptidase 24.16

Dauch, P, Barelli, H, Vincent, J P, Checler, F

Journal:

Biochemical Journal

Year:

1991

Language:

english

File:

PDF, 976 KB

english, 1991

93

Nuclear TP53: An unraveled function as transcriptional repressor of PINK1

Checler, Frédéric, Goiran, Thomas, Alves da Costa, Cristine

Journal:

Year:

2018

Language:

english

File:

PDF, 883 KB

english, 2018

94

α-Secretase-Derived Product of β-Amyloid Precursor Protein Is Decreased by Presenilin 1 Mutations Linked to Familial Alzheimer's Disease

Karine Ancolio, Philippe Marambaud, Pascale Dauch, Frédéric Checler

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 751 KB

english, 1997

95

10.1038/ncb1101-1030

Armogida, Marianna, Petit, Agnès, Vincent, Bruno, Scarzello, Sabine, da Costa, Cristine Alves, Checler, Frédéric

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 170 KB

english, 2001

96

Wild-Type and Mutated Nicastrins Do Not Display Aminopeptidase M- and B-like Activities

Anissa Fergani, G. Yu, Peter St. George-Hyslop, Frédéric Checler

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 56 KB

english, 2001

97

Vascular and parenchymal Aβ deposition in the aging dog: correlation with behavior

M.-A Colle, J.-J Hauw, F Crespeau, T Uchihara, H Akiyama, F Checler, P Pageat, C Duykaerts

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 487 KB

english, 2000

98

The beta-secretase-derived C-terminal fragment of APP (C99): a key determinant for intraneuronal pathology in the 3xTgAD mouse

Lauritzen, Inger, Pardossi-Piquard, Raphaelle, Druon, Charlotte, Brigham, Elizabeth, Abraham, Daniel, Ranaldi, Sébatien, Chami, Linda, Dunys, Julie, Checler, Fréderic

Journal:

Molecular Neurodegeneration

Year:

2013

Language:

english

File:

PDF, 66 KB

english, 2013

99

Parkin acts as a transcription factor modulating presenilin-1 and presenilin-2 promoter transactivations

Duplan, Eric, Sévalle, Jean, Viotti, Julien, Goiran, Thomas, Bauer, Charlotte, Renbaum, Paul, Levy-Lahad, Ephrat, Gautier, Clément A, Corti, Olga, Leroudier, Nathalie, Checler, Frédéric, da Costa, Cri

Journal:

Molecular Neurodegeneration

Year:

2013

Language:

english

File:

PDF, 87 KB

english, 2013

100

Aβ42 oligomers modulate β-secretase through an XBP-1s-dependent pathway involving HRD1

Gerakis, Yannis, Dunys, Julie, Bauer, Charlotte, Checler, Fréderic

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.64 MB

english, 2016

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