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51

Inhibitors of the Interactions between HIV-1 IN and the Cofactor LEDGF/p75

Dr. Laura De Luca, Dr. Stefania Ferro, Dr. Francesca Morreale, Dr. Sara De Grazia, Prof. Alba Chimirri

Journal:

Year:

2011

Language:

english

File:

PDF, 471 KB

english, 2011

52

ChemInform Abstract: Anti-HIV Agents. Part 4. Synthesis and in vitro Anti-HIV Activity of Novel 1-(2,6-Difluorophenyl)-1H,3H-Thiazolo(3,4-a)benzimidazoles.

A. CHIMIRRI, S. GRASSO, C. MOLICA, A.-M. MONFORTE, P. MONFORTE, M. ZAPPALA, R. SCOPELLITI

Journal:

Year:

1996

File:

PDF, 32 KB

1996

53

2-(2,6-Dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors

A Rao, J Balzarini, A Carbone, A Chimirri, E De Clercq, A.M Monforte, P Monforte, C Pannecouque, M Zappalà

Journal:

Antiviral Research

Year:

2004

Language:

english

File:

PDF, 84 KB

english, 2004

54

Comparison of the α and β isomeric forms of the detergent n-dodecyl-D-maltoside for solubilizing photosynthetic complexes from pea thylakoid membranes

Cristina Pagliano, Simone Barera, Fabiana Chimirri, Guido Saracco, James Barber

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2012

Language:

english

File:

PDF, 1.16 MB

english, 2012

55

Insight into the Fundamental Interactions between LEDGF Binding Site Inhibitors and Integrase Combining Docking and Molecular Dynamics Simulations

De Luca, Laura, Morreale, Francesca, Chimirri, Alba

Journal:

Journal of Chemical Information and Modeling

Year:

2012

Language:

english

File:

PDF, 1.92 MB

english, 2012

56

Pharmacophore-Based Design of HIV-1 Integrase Strand-Transfer Inhibitors

Barreca, Maria Letizia, Ferro, Stefania, Rao, Angela, De Luca, Laura, Zappalà, Maria, Monforte, Anna-Maria, Debyser, Zeger, Witvrouw, Myriam, Chimirri, Alba

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 239 KB

english, 2005

57

Preclinical Evaluation of 1H-Benzylindole Derivatives as Novel Human Immunodeficiency Virus Integrase Strand Transfer Inhibitors

Hombrouck, A., Van Remoortel, B., Michiels, M., Noppe, W., Christ, F., Eneroth, A., Sahlberg, B. L., Benkestock, K., Vrang, L., Johansson, N. G., Barreca, M. L., De Luca, L., Ferro, S., Chimirri, A.,

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2008

Language:

english

File:

PDF, 279 KB

english, 2008

58

Quinolones potentiate cefazolin-induced seizures in DBA/2 mice.

De Sarro, A, Zappala, M, Chimirri, A, Grasso, S, De Sarro, G B

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1993

Language:

english

File:

PDF, 1.23 MB

english, 1993

59

ChemInform Abstract: Compounds with Potential Antitumor Activity. Part 7. Synthesis and Antitumor Activity of 1-Aryl-N,N′-di(1,3,4-thiadiazol-2-yl)methylenediamines.

CHIMIRRI, A., GRASSO, S., MONFORTE, P., FENECH, G., ZAPPALA, M., MONFORTE, A.-M.

Journal:

Year:

1989

File:

PDF, 108 KB

1989

60

13C NMR study of tetrahydrothiazolo-[3,2-d][1,4]benzodiazepin-3[2H]-ones

M. Zappalá, G. Romeo, S. Grasso, A. Chimirri, A. M. Mon-Forte

Journal:

Magnetic Resonance in Chemistry

Year:

1989

Language:

english

File:

PDF, 262 KB

english, 1989

61

Comparative molecular field analysis (CoMFA) and docking studies of non-nucleoside HIV-1 RT inhibitors (NNIs)

M.L. Barreca, A. Carotti, A. Carrieri, A. Chimirri, A.M. Monforte, M. Pellegrini Calace, A. Rao

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 706 KB

english, 1999

62

Synthesis of new 2,3-diaryl-1,3-thiazolidin-4-ones as anti-HIV agents

Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappalà

Journal:

Year:

2004

Language:

english

File:

PDF, 160 KB

english, 2004

63

Comparative anticonvulsant activity of some 2,3-benzodiazepine derivatives in rodents

Giovambattista De Sarro, Guido Ferreri, Pietro Gareri, Emilio Russo, Angela De Sarro, Rosaria Gitto, Alba Chimirri

Journal:

Pharmacology Biochemistry and Behavior

Year:

2003

Language:

english

File:

PDF, 280 KB

english, 2003

64

Diketoacid chelating ligands as dual inhibitors of HIV-1 integration process

Rogolino, Dominga, Carcelli, Mauro, Compari, Carlotta, De Luca, Laura, Ferro, Stefania, Fisicaro, Emilia, Rispoli, Gabriele, Neamati, Nouri, Debyser, Zeger, Christ, Frauke, Chimirri, Alba

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 210 KB

english, 2014

65

Identification of 3,4-Dihydroisoquinoline-2(1 H )-sulfonamides as Potent Carbonic Anhydrase Inhibitors: Synthesis, Biological Evaluation, and Enzyme−Ligand X-ray Studies

Gitto, Rosaria, Agnello, Stefano, Ferro, Stefania, De Luca, Laura, Vullo, Daniela, Brynda, Jiri, Mader, Pavel, Supuran, Claudiu T., Chimirri, Alba

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 3.79 MB

english, 2010

66

Vertigo/dizziness as a Drugs′ adverse reaction

De Sarro, Giovambattista, Mazzitello, Carmela, Mumoli, Laura, Palleria, Caterina, Aiello, Rossana, Altomonte, Mariolina, Chimirri, Serafina, Citraro, Rita

Journal:

Journal of Pharmacology and Pharmacotherapeutics

Year:

2013

Language:

english

File:

PDF, 633 KB

english, 2013

67

Specifying the Ethics of Teleogenetic Collaboration for Research with Children and Other Vital Forces: a Critical Inquiry into Dialectical Praxis Psychology via Posthumanist Theorizing

Chimirri, Niklas A.

Journal:

Year:

2019

Language:

english

File:

PDF, 551 KB

english, 2019

68

ChemInform Abstract: Synthesis and Anticonvulsant Properties of 2,3,3a,4-Tetrahydro-1H-pyrrolo[1,2-a]benzimidazol-1-one Derivatives.

Alba Chimirri, Angela De Sarro, Giovambattista De Sarro, Rosaria Gitto, Maria Zappala

Journal:

Year:

2002

File:

PDF, 26 KB

2002

69

Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains

Maria Letizia Barreca, Angela Rao, Laura De Luca, Nunzio Iraci, Anna-Maria Monforte, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Alba Chimirri

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 371 KB

english, 2007

70

Discovery of a Novel and Highly Potent Noncompetitive AMPA Receptor Antagonist

Gitto, Rosaria, Barreca, Maria Letizia, De Luca, Laura, De Sarro, Giovambattista, Ferreri, Guido, Quartarone, Silvana, Russo, Emilio, Constanti, Andrew, Chimirri, Alba

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 75 KB

english, 2003

71

GYKI 52466 and related 2,3-benzodiazepines as anticonvulsant agents in DBA/2 mice

Giovambattista De Sarro, Alba Chimirri, Angela De Sarro, Rosaria Gitto, Silvana Grasso, Piero Giusti, Astrid G. Chapman

Journal:

European Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 1.09 MB

english, 1995

72

AMPA receptor antagonists

Chimirri, Alba, Gitto, Rosaria, Zappalà, Maria

Journal:

Expert Opinion on Therapeutic Patents

Year:

1999

Language:

english

File:

PDF, 140 KB

english, 1999

73

Synthesis and Biological Activity of Novel 1H,3H-Thiazolo[3,4-a]Benzimidazoles: Non-nucleoside Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors

Chimirri, A., Grasso, S., Monforte, P., Rao, A., Zappala, M., Monforte, A., Pannecouque, C., Witvrouw, M., Balzarini, J., De Clercq, E.

Journal:

Antiviral Chemistry & Chemotherapy

Year:

1999

Language:

english

File:

PDF, 225 KB

english, 1999

74

Synthesis, Biological Activity, Pharmacokinetic Properties and Molecular Modelling Studies of Novel 1H,3H-Oxazolo[3,4-a]Benzimidazoles: Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

Chimirri, A., Monforte, P., Rao, A., Zappala, M., Monforte, A., De Sarro, G., Pannecouque, C., Witvrouw, M., Balzarini, J., De Clercq, E.

Journal:

Antiviral Chemistry & Chemotherapy

Year:

2001

Language:

english

File:

PDF, 229 KB

english, 2001

75

ChemInform Abstract: Synthesis and Stereochemistry of Tetrahydrothiazolo(3,2-d)(1,4)benzodiazepin-3(2H)-ones.

ZAPPALA, M., CHIMIRRI, A., GRASSO, S., ROMEO, G., MONFORTE, A. M.

Journal:

Year:

1989

File:

PDF, 113 KB

1989

76

ChemInform Abstract: Synthesis and Stereochemistry of Novel (1,2,4)Oxadiazolo(4,5-a)(1,5)benzodiazepine Derivatives.

CHIMIRRI, A., GRASSO, S., OTTANA, R., ROMEO, G., ZAPPALA, M.

Journal:

Year:

1990

File:

PDF, 129 KB

1990

77

Synthesis and anti-HIV Activity of 2,3-Diaryl-1,3-thiazolidin-4-(thi)one Derivatives.

Angela Rao, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappala

Journal:

Year:

2003

File:

PDF, 139 KB

2003

78

Synthesis and Anticonvulsant Activity of N-3 Substituted 2,3-Benzodiazepines.

Silvana Quartarone, Roberta Caruso, Valerie Orlando, Emilio Russo, Giovambattista De Sarro, Alba Chimirri

Journal:

Year:

2004

File:

PDF, 61 KB

2004

79

Induced-Fit Docking Approach Provides Insight into the Binding Mode and Mechanism of Action of HIV-1 Integrase Inhibitors

Maria Letizia Barreca, Nunzio Iraci, Laura De Luca, Alba Chimirri

Journal:

Year:

2009

Language:

english

File:

PDF, 891 KB

english, 2009

80

Identification of Potent and Selective Human Carbonic Anhydrase VII (hCA VII) Inhibitors

Rosaria Gitto, Stefano Agnello, Stefania Ferro, Daniela Vullo, Claudiu T. Supuran, Alba Chimirri

Journal:

Year:

2010

Language:

english

File:

PDF, 203 KB

english, 2010

81

Determination of a potent non-competitive AMPA receptor antagonist in rat brain

M. Rizzo, D. Ventrice, F. Casale, G. De Sarro, R. Gitto, A. Chimirri

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 232 KB

english, 2007

82

Determination of 2,3-benzodiazepine derivatives in rat plasma by high-performance liquid chromatography

M Rizzo, G De Sarro, R Gitto, M Zappalà, A Chimirri

Journal:

Journal of Chromatography A

Year:

1999

Language:

english

File:

PDF, 196 KB

english, 1999

83

Pharmacophore Modeling as an Efficient Tool in the Discovery of Novel Noncompetitive AMPA Receptor Antagonists

Barreca, M.L., Gitto, R., Quartarone, S., De Luca, L., De Sarro, G., Chimirri, A.

Journal:

Journal of Chemical Information and Modeling

Year:

2003

Language:

english

File:

PDF, 196 KB

english, 2003

84

Enantiomeric resolution of anti-HIV agents on a cellulose derivative chiral stationary phase

P. Ficarra, R. Ficarra, A. Chimirri, G. Romeo, S. Tommasini, M. L. Calabrò, D. Costantino, A. M. Monforte, M. Carulli

Journal:

Chromatographia

Year:

1994

Language:

english

File:

PDF, 380 KB

english, 1994

85

Synthesis and biological profile of new 1,2,3,4-tetrahydroisoquinolines as selective carbonic anhydrase inhibitors

Rosaria Gitto, Francesca Maria Damiano, Laura De Luca, Stefania Ferro, Daniela Vullo, Claudiu T. Supuran, Alba Chimirri

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 265 KB

english, 2011

86

Selective induction of apoptosis in multidrug resistant HL60R cells by the thiazolobenzoimidazole derivative 1-(2,6-difluorophenyl)-1H,3H-thiazolo [3,4-a] benzimidazole (TBZ)

S Grimaudo, M Tolomeo, A Chimirri, M Zappala, R.A Gancitano, N D’Alessandro

Journal:

European Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 580 KB

english, 1998

87

Synthesis and Biological Characterization of 3-Substituted 1 H -Indoles as Ligands of GluN2B-Containing N -Methyl- d -aspartate Receptors. Part 2

Gitto, Rosaria, De Luca, Laura, Ferro, Stefania, Buemi, Maria R., Russo, Emilio, De Sarro, Giovambattista, Chisari, Mariangela, Ciranna, Lucia, Chimirri, Alba

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 395 KB

english, 2012

88

ChemInform Abstract: An Unexpected Reaction between 2,3-Dihydro-2,2,4-trimethyl-1H-1,5-benzodiazepine and Mercaptoacetic Acid.

CHIMIRRI, A., GRASSO, S., OTTANA, R., ROMEO, G., VALLE, G., ZAPPALA, M.

Journal:

Year:

1988

File:

PDF, 110 KB

1988

89

ChemInform Abstract: Compounds with Potential Antitumor Activity. Part 6. 2-Alkyl-3-(2-(1,3,4-thiadiazolyl))-4-thiazolidinones.

GRASSO, S., CHIMIRRI, A., MONFORTE, P., FENECH, G., ZAPPALA, M., MONFORTE, A. M.

Journal:

Year:

1989

File:

PDF, 109 KB

1989

90

ChemInform Abstract: Compounds with Potential Antitumor Activity. Part 5. 3-(2-(1,3,4-Thiadiazolyl))-4-thiazolidinones.

CHIMIRRI, A., GRASSO, S., MONFORTE, P., FENECH, G., ZAPPALA, M.

Journal:

Year:

1987

File:

PDF, 106 KB

1987

91

Theorizing Research Ethics for the Study of Psychological Phenomena from Within Relational Everyday Life

Hilppö, Jaakko, Chimirri, Niklas Alexander, Rajala, Antti

Journal:

Year:

2019

Language:

english

File:

PDF, 280 KB

english, 2019

92

ChemInform Abstract: Synthesis and Structural Features of New Cyclofunctionalized Benzimidazoles.

Alba Chimirri, Anna Maria Monforte, Pietro Monforte, Francesco Nicolo, Angela Rao, Maria Zappala

Journal:

Year:

2000

File:

PDF, 29 KB

2000

93

Optimization of a LC method for the enantioseparation of a non-competitive glutamate receptor antagonist, by experimental design methodology

P. Donato, R. Stancanelli, M.L. Calabrò, S. Tommasini, P. Cutroneo, M. Guardo, B. Pagano, A. Chimirri, P. Ficarra, R. Ficarra

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2006

Language:

english

File:

PDF, 822 KB

english, 2006

94

4-[1-(4-Fluorobenzyl)-4-hydroxy-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoic acid as a prototype to develop dual inhibitors of HIV-1 integration process

Laura De Luca, Rosaria Gitto, Frauke Christ, Stefania Ferro, Sara De Grazia, Francesca Morreale, Zeger Debyser, Alba Chimirri

Journal:

Antiviral Research

Year:

2011

Language:

english

File:

PDF, 517 KB

english, 2011

95

18 Synthesis and metabolic study of 1H,3H-oxazolo[3,4-a]benzimidazoles, a new class of non-nucleoside HIV-1 RT inhibitors

A. Chimirri, E. De Clercq, A.M. Monforte, P. Monforte, C. Pannecouque, A. Rao, M. Witvrouw, M. Zappalà

Journal:

Antiviral Research

Year:

2000

Language:

english

File:

PDF, 54 KB

english, 2000

96

Synthesis and anticonvulsant properties of 2,3,3a,4-tetrahydro-1H-pyrrolo[1,2-a]benzimidazol-1-ones

Chimirri, Alba, De Sarro, Angelina, De Sarro, Giovambattista, Grasso, Silvana, Trimarchi, Giuseppe R., Zappala, Maria

Journal:

Journal of Medicinal Chemistry

Year:

1989

Language:

english

File:

PDF, 404 KB

english, 1989

97

A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus

Lefebvre, David J., De Vleeschauwer, Annebel R., Goris, Nesya, Van Borm, Steven, Chimirri, Alba, Monforte, Anna Maria, Valdazo-Gonzalez, Begona, King, Donald P., Neyts, Johan, De Clercq, Kris

Journal:

Biochemical and Biophysical Research Communications

Year:

2014

Language:

english

File:

PDF, 381 KB

english, 2014

98

A Simple, One-Pot Synthesis of Novel 1 H , 3 H -Thiazolo-[3,4- a ]benzimidazoles

Chimirri, Alba, Grasso, Silvana, Monforte, Pietro, Romeo, Giovanni, Zappalà, Maria

Journal:

Year:

1988

File:

PDF, 131 KB

1988

99

Inhibition of the Interaction between HIV-1 Integrase and its Cofactor LEDGF/p75: A Promising Approach in Anti-Retroviral Therapy

De Luca, L., Ferro, S., Morreale, F., Chimirri, A.

Journal:

Mini Reviews in Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 930 KB

english, 2011

100

ChemInform Abstract: Thiazolobenzimidazoles

CHIMIRRI, A., GRASSO, S., ROMEO, G., ZAPPALA, M.

Journal:

Year:

1989

File:

PDF, 88 KB

1989

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