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1

New Model for Estimating Glomerular Filtration Rate in Patients With Cancer

Janowitz, Tobias, Williams, Edward H., Marshall, Andrea, Ainsworth, Nicola, Thomas, Peter B., Sammut, Stephen J., Shepherd, Scott, White, Jeff, Mark, Patrick B., Lynch, Andy G., Jodrell, Duncan I., Ta

Journal:

Journal of Clinical Oncology

Year:

2017

Language:

english

File:

PDF, 1.11 MB

english, 2017

2

Model selection and sample size adaptation: HYPAZ trial

Simon Bond, Adrian Mander, Duncan Jodrell, Joseph Cheryian

Journal:

Year:

2011

Language:

english

File:

PDF, 121 KB

english, 2011

3

A novel Phase I/IIa design for early phase oncology studies and its application in the evaluation of MK-0752 in pancreatic cancer

John Whitehead, Helene Thygesen, Thomas Jaki, Scot Davies, Sarah Halford, Helen Turner, Natalie Cook, Duncan Jodrell

Journal:

Statistics in Medicine

Year:

2012

Language:

english

File:

PDF, 638 KB

english, 2012

4

Loss of P53 Function Activates JAK2–STAT3 Signaling to Promote Pancreatic Tumor Growth, Stroma Modification, and Gemcitabine Resistance in Mice and is Associated With Patient Survival

Wörmann, Sonja M., Song, Liang, Ai, Jiaoyu, Diakopoulos, Kalliope N., Görgülü, Kivanc, Ruess, Dietrich, Campbell, Andrew, Doglioni, Claudio, Jodrell, Duncan, Neesse, Albrecht, Demir, Ekin I., Karpatha

Journal:

Gastroenterology

Year:

2016

Language:

english

File:

PDF, 19.63 MB

english, 2016

5

High-Performance Liquid Chromatographic Technique for the Simultaneous Determination of Lactone and Hydroxy Acid Forms of Camptothecin and SN-38 in Tissue Culture Media and Cancer Cells

Gary Boyd, John F. Smyth, Duncan I. Jodrell, Jeffrey Cummings

Journal:

Analytical Biochemistry

Year:

2001

Language:

english

File:

PDF, 97 KB

english, 2001

6

Validation of real-time reverse-transcription-polymerase chain reaction for quantification of capecitabine-metabolizing enzymes

Janet S. Macpherson, Duncan I. Jodrell, Sylvie M. Guichard

Journal:

Analytical Biochemistry

Year:

2006

Language:

english

File:

PDF, 511 KB

english, 2006

7

Simultaneous determination of capecitabine and its metabolites by HPLC and mass spectrometry for preclinical and clinical studies

Sylvie M. Guichard, Iain Mayer, Duncan I. Jodrell

Journal:

Journal of Chromatography B

Year:

2005

Language:

english

File:

PDF, 100 KB

english, 2005

8

Simultaneous determination of decitabine and vorinostat (Suberoylanalide hydroxamic acid, SAHA) by liquid chromatography tandem mass spectrometry for clinical studies

Katan Patel, Sylvie M. Guichard, Duncan I. Jodrell

Journal:

Journal of Chromatography B

Year:

2008

Language:

english

File:

PDF, 479 KB

english, 2008

9

Development of a gradient elution high-performance liquid chromatography assay with ultraviolet detection for the determination in plasma of the anticancer peptide [Arg6, d-Trp7,9, mePhe8]-substance P (6–11) (antagonist G), its major metabolites and a C-terminal pyrene-labelled conjugate

Jeffrey Cummings, Alexander J MacLellan, Margo Mark, Duncan I Jodrell

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1999

Language:

english

File:

PDF, 154 KB

english, 1999

10

ERβ isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates

Newton ACS Wong, Roger DG Malcomson, Duncan I Jodrell, Nigel P Groome, David J Harrison, Philippa TK Saunders

Journal:

The Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 310 KB

english, 2005

11

Phase II trial and pharmacokinetic assessment of intravenous melphalan in patients with advanced prostate cancer

David C. Smith, Duncan I. Jodrell, Merrill J. Egorin, Roy M. Ambinder, Eleanor G. Zuhowski, Willi Kreis, Peter G. Ellis, Donald L. Trump

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1993

Language:

english

File:

PDF, 701 KB

english, 1993

12

Factors influencing the cellular accumulation of SN-38 and camptothecin

Jeffrey Cummings, Gary Boyd, Janet S. Macpherson, Helga Wolf, Gillian Smith, John F. Smyth, Duncan I. Jodrell

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2002

Language:

english

File:

PDF, 134 KB

english, 2002

13

A phase I study of the trinuclear platinum compound, BBR

Charlie Gourley, James Cassidy, Chris Edwards, Leslie Samuel, Donald Bisset, Gabriella Camboni, Anne Young, Dorothy Boyle, Duncan Jodrell

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2004

Language:

english

File:

PDF, 235 KB

english, 2004

14

Stable XIAP knockdown clones of HCT116 colon cancer cells are more sensitive to TRAIL, taxanes and irradiation in vitro

Kate Connolly, Richard Mitter, Morwenna Muir, Duncan Jodrell, Sylvie Guichard

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 524 KB

english, 2009

15

Influence of the antacid Maalox on the pharmacokinetics of capecitabine in cancer patients

Bruno Reigner, Saly Clive, Jim Cassidy, Duncan Jodrell, Rainer Schulz, Timothy Goggin, Ludger Banken, Brigitte Roos, Masahiro Utoh, Thomas Mulligan, Erhard Weidekamm

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 114 KB

english, 1999

16

Bioequivalence of two tablet formulations of capecitabine and exploration of age, gender, body surface area, and creatinine clearance as factors influencing systemic exposure in cancer patients

Jim Cassidy, Chris Twelves, David Cameron, William Steward, Ken O'Byrne, Duncan Jodrell, Ludger Banken, Timothy Goggin, David Jones, Brigitte Roos, Erine Bush, Erhard Weidekamm, Bruno Reigner

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 185 KB

english, 1999

17

The impact of prognosis without treatment on doctors' and patients' resource allocation decisions and its relevance to new drug recommendation processes

D. Ross Camidge, James J. Oliver, Carolyn Skinner, Ben Attwood, Fiona Nussey, Duncan Jodrell, David J. Webb

Journal:

British Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 493 KB

english, 2008

18

Recent developments in adjuvant chemotherapy for colorectal cancer

GILLIAN H KNOWLES, DUNCAN I JODRELL

Journal:

European Journal of Cancer Care

Year:

1997

Language:

english

File:

PDF, 473 KB

english, 1997

19

Optimization of the Antitumor Activity of Sequence-specific Pyrrolobenzodiazepine Derivatives Based on their Affinity for ABC Transporters

Maciej Kaliszczak, Dyeison Antonow, Katan I. Patel, Philip Howard, Duncan I. Jodrell, David E. Thurston, Sylvie M. Guichard

Journal:

The AAPS Journal

Year:

2010

Language:

english

File:

PDF, 458 KB

english, 2010

20

Glucuronidation as a mechanism of intrinsic drug resistance in colon cancer cells: contribution of drug transport proteins

Jeffrey Cummings, Noam Zelcer, John D Allen, Denggao Yao, Gary Boyd, Mark Maliepaard, Thomas H Friedberg, John F Smyth, Duncan I Jodrell

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 204 KB

english, 2004

21

Predictive in vivo animal models and translation to clinical trials

Natalie Cook, Duncan I. Jodrell, David A. Tuveson

Journal:

Drug Discovery Today

Year:

2012

Language:

english

File:

PDF, 454 KB

english, 2012

22

Enhanced clearance of topoisomerase I inhibitors from human colon cancer cells by glucuronidation

Jeffrey Cummings, Gary Boyd, Brian T. Ethell, Janet S. Macpherson, Brian Burchell, John F. Smyth, Duncan I. Jodrell

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 134 KB

english, 2002

23

Cisplatin and carboplatin: a guide to administration

NORA LAWSON, DUNCAN JODRELL, ALASTAIR McMURRAY

Journal:

European Journal of Cancer Care

Year:

1993

Language:

english

File:

PDF, 387 KB

english, 1993

24

The biochemical pharmacology of the thymidylate synthase inhibitor, 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583)

Ann L. Jackman, David R. Newell, William Gibson, Duncan I. Jodrell, Gordon A. Taylor, Joel A. Bishop, Leslie R. Hughes, A. Hilary Calvert

Journal:

Biochemical Pharmacology

Year:

1991

Language:

english

File:

PDF, 1009 KB

english, 1991

25

The in vivo metabolic stability of dipeptide analogues of the quinazoline antifolate, ICI 198583, in mice

Duncan I. Jodrell, William Gibson, Graham M.F. Bisset, F.Thomas Boyle, Ian R. Judson, Ann L. Jackman

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 468 KB

english, 1993

26

Longitudinal quality of life and quality adjusted survival in a randomised controlled trial comparing six months of bolus fluorouracil/leucovorin vs. twelve weeks of protracted venous infusion fluorouracil as adjuvant chemotherapy for colorectal cancer

Ian Chau, Andrew R. Norman, David Cunningham, Tim Iveson, Mark Hill, Tamas Hickish, Fiona Lofts, Duncan Jodrell, Andrew Webb, Diana Tait, Paul J. Ross, Pat Shellito, Jacqueline R. Oates

Journal:

European Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 218 KB

english, 2005

27

Gene expression predicts differential capecitabine metabolism, impacting on both pharmacokinetics and antitumour activity

Sylvie M. Guichard, Janet S. Macpherson, Iain Mayer, Eilidh Reid, Morwenna Muir, Michael Dodds, Susan Alexander, Duncan I. Jodrell

Journal:

European Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 195 KB

english, 2008

28

Developing and piloting a nurse-led model of follow-up in the multidisciplinary management of colorectal cancer

Gillian Knowles, Linda Sherwood, Malcom G. Dunlop, Gail Dean, Duncan Jodrell, Catriona McLean, Elizabeth Preston

Journal:

European Journal of Oncology Nursing

Year:

2007

Language:

english

File:

PDF, 275 KB

english, 2007

29

The perceived information needs of patients receiving adjuvant chemotherapy for surgically resected colorectal cancer

Gillian Knowles, Alison Tierney, Duncan Jodrell, Ann Cull

Journal:

European Journal of Oncology Nursing

Year:

1999

File:

PDF, 1.38 MB

1999

30

Adaptive designs for dual-agent phase I dose-escalation studies

Harrington, Jennifer A., Wheeler, Graham M., Sweeting, Michael J., Mander, Adrian P., Jodrell, Duncan I.

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2013

Language:

english

File:

PDF, 498 KB

english, 2013

31

Inhibition of Cancer Cell Growth by Ruthenium(II) Arene Complexes

Morris, Robert E., Aird, Rhona E., del Socorro Murdoch, Piedad, Chen, Haimei, Cummings, Jeff, Hughes, Nathan D., Parsons, Simon, Parkin, Andrew, Boyd, Gary, Jodrell, Duncan I., Sadler, Peter J.

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 109 KB

english, 2001

32

Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD

Ubhi, Baljit K., Cheng, Kian Kai, Dong, Jiyang, Janowitz, Tobias, Jodrell, Duncan, Tal-Singer, Ruth, MacNee, William, Lomas, David A., Riley, John H., Griffin, Julian L., Connor, Susan C.

Journal:

Molecular BioSystems

Year:

2012

Language:

english

File:

PDF, 1.97 MB

english, 2012

33

Tuning the Reactivity of Osmium(II) and Ruthenium(II) Arene Complexes under Physiological Conditions

Peacock, Anna F. A., Habtemariam, Abraha, Fernández, Rafael, Walland, Victoria, Fabbiani, Francesca P. A., Parsons, Simon, Aird, Rhona E., Jodrell, Duncan I., Sadler, Peter J.

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 277 KB

english, 2006

34

Capecitabine as Adjuvant Treatment for Stage III Colon Cancer

Twelves, Chris, Wong, Alfred, Nowacki, Marek P., Abt, Markus, Burris, Howard, Carrato, Alfredo, Cassidy, Jim, Cervantes, Andrés, Fagerberg, Jan, Georgoulias, Vassilis, Husseini, Fares, Jodrell, Duncan

Journal:

Boston Medical and Surgical Journal

Year:

2005

Language:

english

File:

PDF, 124 KB

english, 2005

35

Design, Synthesis, and Biological Evaluation of an Allosteric Inhibitor of HSET that Targets Cancer Cells with Supernumerary Centrosomes

Watts, Ciorsdaidh A., Richards, Frances M., Bender, Andreas, Bond, Peter J., Korb, Oliver, Kern, Oliver, Riddick, Michelle, Owen, Paul, Myers, Rebecca M., Raff, Jordan, Gergely, Fanni, Jodrell, Duncan

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 3.01 MB

english, 2013

36

The EGFR demonstrates linear signal transmission

Oyarzún, Diego A., Bramhall, Jo L., López-Caamal, Fernando, Richards, Frances M., Jodrell, Duncan I., Krippendorff, Ben-Fillippo

Journal:

Integrative Biology

Year:

2014

Language:

english

File:

PDF, 3.30 MB

english, 2014

37

Development of guidelines for gentamicin dosing

Thomson, A. H., Duncan, N., Silverstein, B., Alcock, S., Jodrell, D.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

1996

Language:

english

File:

PDF, 857 KB

english, 1996

38

The use of error-category mapping in pharmacokinetic model analysis of dynamic contrast-enhanced MRI data

Gill, Andrew B., Anandappa, Gayathri, Patterson, Andrew J., Priest, Andrew N., Graves, Martin J., Janowitz, Tobias, Jodrell, Duncan I., Eisen, Tim, Lomas, David J.

Journal:

Magnetic Resonance Imaging

Year:

2015

Language:

english

File:

PDF, 873 KB

english, 2015

39

Progress in pancreatic cancer: moving beyond gemcitabine?

Basu, Bristi, Jodrell, Duncan

Journal:

Expert Review of Anticancer Therapy

Year:

2012

Language:

english

File:

PDF, 625 KB

english, 2012

40

Combenefit: An interactive platform for the analysis and visualisation of drug combinations

Di Veroli, Giovanni Y., Fornari, Chiara, Wang, Dennis, Mollard, Séverine, Bramhall, Jo L., Richards, Frances M., Jodrell, Duncan I.

Journal:

Year:

2016

Language:

english

File:

PDF, 254 KB

english, 2016

41

Effects of nitric oxide manipulation on the disposition of platinum in an experimental glioma model

Malcolm, George P., Jodrell, Duncan I., MacLellan, Alexander, Swaroop, Gopal R., Kelly, Paul A. T., Whittle, Ian R.

Journal:

Year:

1998

Language:

english

File:

PDF, 192 KB

english, 1998

42

Understanding the complexity of porous graphitic carbon (PGC) chromatography: Modulation of mobile-stationary phase interactions overcomes loss of retention and reduces variability

Bapiro, Tashinga E., Richards, Frances M, Jodrell, Duncan I

Journal:

Analytical Chemistry

Year:

2016

Language:

english

File:

PDF, 494 KB

english, 2016

43

Gemcitabine delivery and stromal component analysis in primary murine pancreatic tumours and liver metastasis

Klein, Lukas, Hessmann, Elisabeth, Bapiro, Tashinga E., Frese, Kris, Richards, Frances M., Jodrell, Duncan I., Gress, Thomas M., Ellenrieder, Volker, Neesse, Albrecht

Journal:

Year:

2016

Language:

english

File:

PDF, 49 KB

english, 2016

44

MECHANISMS OF HYPERTENSION FOLLOWING VASCULAR ENDOTHELIAL GROWTH FACTOR INHIBITION: THE HYPAZ TRIAL

Yang, Lucy, McGeoch, Adam, Hubsch, Annette, Gajendragadkar, Parag, McEniery, Carmel, Mir, Fraz, Maki-Petaja, Kaisa, Ramenatte, Nicola, Anandappa, Gayathri, Bond, Simon, Wilkinson, Ian, Jodrell, Duncan

Journal:

Journal of the American College of Cardiology

Year:

2016

Language:

english

File:

PDF, 620 KB

english, 2016

45

Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity

Flint, Thomas R., Janowitz, Tobias, Connell, Claire M., Roberts, Edward W., Denton, Alice E., Coll, Anthony P., Jodrell, Duncan I., Fearon, Douglas T.

Journal:

Cell Metabolism

Year:

2016

Language:

english

File:

PDF, 3.46 MB

english, 2016

46

Quantitative FastFUCCI assay defines cell cycle dynamics at single-cell level

Koh, Siang-Boon, Mascalchi, Patrice, Rodriguez, Esther, Lin, Yao, Jodrell, Duncan I., Richards, Frances M., Lyons, Scott K.

Journal:

Journal of Cell Science

Year:

2016

Language:

english

File:

PDF, 4.73 MB

english, 2016

47

An automated fitting procedure and software for dose-response curves with multiphasic features

Veroli, Giovanni Y. Di, Fornari, Chiara, Goldlust, Ian, Mills, Graham, Koh, Siang Boon, Bramhall, Jo L, Richards, Frances M., Jodrell, Duncan I.

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

48

Comparison of Iterative-Two Stage and Bootstrap Sampling Approaches in the Development of a Population Pharmacokinetic Model

Sridhara, Rajeshwari, Eisenberger, Mario A., Reyno, Leonard M., Jodrell, Duncan I., Sinibaldi, Victoria J., Zubowski, Eleanor G., Egorin, Merrill J.

Journal:

IFAC Proceedings Volumes

Year:

1997

Language:

english

File:

PDF, 1.09 MB

english, 1997

49

Metabolic Reprogramming of Fibroblasts to Enhance Gemcitabine Availability in Murine Pancreatic Cancer

Patzak, Melanie S., Hessmann, Elisabeth, Kari, Vijayalakshmi, Richards, Frances M., Jodrell, Duncan I., Johnsen, Steven A., Ellenrieder, Volker, Neesse, Albrecht

Journal:

Year:

2017

Language:

english

File:

PDF, 50 KB

english, 2017

50

Cancer Immunotherapy Trials Underutilize Immune Response Monitoring

Connell, Claire M., Raby, Sophie E.M., Beh, Ian, Flint, Thomas R., Williams, Edward H., Fearon, Douglas T., Jodrell, Duncan I., Janowitz, Tobias

Journal:

Year:

2017

Language:

english

File:

PDF, 141 KB

english, 2017

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